| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Latruffe N et al. | Stimulation of protein kinase C activity by compactin in vascular smooth muscle cells. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7503722 |
| Ramsey RB et al. | The effect of non-ionic detergents and phospholipase A on enzymes involved in adult rat brain sterol biosynthesis from (2-14C)-mevalonic acid in vitro. | 1974 | Biochem. Biophys. Res. Commun. | pmid:4441393 |
| Hatanaka H et al. | Accumulation of a sterol intermediate during reaction in the presence of homocysteine with cell-free extract of yeast. | 1974 | Biochem. Biophys. Res. Commun. | pmid:4608604 |
| Mitropoulos KA and Gibbons GF | Effect of triarimol on cholesterol biosynthesis in rat-liver subcellular. | 1976 | Biochem. Biophys. Res. Commun. | pmid:962959 |
| Sekler MS and Simoni RD | Mutation in the lumenal part of the membrane domain of HMG-CoA reductase alters its regulated degradation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7818519 |
| Florin-Christensen M et al. | Occurrence of specific sterols in Pneumocystis carinii. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8292026 |
| Miquel K et al. | Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8780704 |
| Aiyar AS et al. | Biogenesis of ubiquinone in rats--an alternate origin of the benzoquinone moiety. | 1971 | Biochem. Biophys. Res. Commun. | pmid:5117559 |
| Barr RM and De Luca LM | The in vivo incorporation of mannose, retinol and mevalonic acid into phospholipids of hamster liver. | 1974 | Biochem. Biophys. Res. Commun. | pmid:4421270 |
| Dunnington DJ et al. | Stimulation of anchorage independent proliferation of human adrenocortical carcinoma cells by inhibition of cholesterol biosynthesis. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2590222 |
| Lee SK et al. | Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20043868 |
| Flach J et al. | The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10733934 |
| Ku EC | Regulation of fatty acid biosynthesis by intermediates of the cholesterol biosynthetic pathway. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8769113 |
| Polo MP and de Bravo MG | Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2. | 2006 | Biochem. Cell Biol. | pmid:16462894 |
| Polo MP et al. | Effect of ethanol on cell growth and cholesterol metabolism in cultured Hep G2 cells. | 2003 | Biochem. Cell Biol. | pmid:14663504 |
| Ellsworth JL et al. | Evidence for sterol-independent regulation of low-density lipoprotein receptor activity in Hep-G2 cells. | 1991 | Biochem. J. | pmid:1930137 |
| Henry A et al. | Dolichol biosynthesis in human malignant cells. | 1991 | Biochem. J. | pmid:1654890 |
| Smith AG and Goad LJ | Sterol biosynthesis by the sea urchin Echinus esculentus. | 1974 | Biochem. J. | pmid:4441383 |
| Rasmussen LM et al. | Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells. | 2001 | Biochem. J. | pmid:11716764 |
| Bolaños JP et al. | Inhibition of sterol but not fatty acid synthesis by valproate in developing rat brain in vivo. | 1990 | Biochem. J. | pmid:2264830 |
| Richards JB and Hemming FW | Dolichols, ubiquinones, geranylgeraniol and farnesol as the major metabolites of mevalonate in Phytophthora cactorum. | 1972 | Biochem. J. | pmid:4643705 |
| Wellburn AR and Hampp R | Uptake of mevalonate and acetate during plastid development. | 1976 | Biochem. J. | pmid:985424 |
| Gough DP and Hemming FW | The characterization and stereochemistry of biosynthesis of dolichols in rat liver. | 1970 | Biochem. J. | pmid:4319540 |
| Flint AP | The activity and kinetic properties of mevalonate kinase in superovulated rat ovary. | 1970 | Biochem. J. | pmid:4321929 |
| Azrolan NI and Coleman PS | A discoordinate increase in the cellular amount of 3-hydroxy-3-methylglutaryl-CoA reductase results in the loss of rate-limiting control over cholesterogenesis in a tumour cell-free system. | 1989 | Biochem. J. | pmid:2705993 |
| Wilton DC | The effect of excess mevalonic acid on ubiquinone and tetrahymanol biosynthesis in Tetrahymena pyriformis. | 1985 | Biochem. J. | pmid:3929773 |
| Wilton DC | The effect of cholesterol on ubiquinone and tetrahymanol biosynthesis in Tetrahymena pyriformis. | 1983 | Biochem. J. | pmid:6418144 |
| Charlton JM et al. | Incorporation of 2-[14C]mevalonic acid into phytoene by isolated chloroplasts. | 1967 | Biochem. J. | pmid:4383323 |
| Disch A et al. | Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714. | 1998 | Biochem. J. | pmid:9657979 |
| Swift IE and Milborrow BV | Retention of the 4-pro-R hydrogen atom of mevalonate at C-2,2' of bacterioruberin in Halobacterium halobium. | 1980 | Biochem. J. | pmid:7406867 |
| Burt VT et al. | The formation of menaquinone-4 (vitamin K) and its oxide in some marine invertebrates. | 1977 | Biochem. J. | pmid:849285 |
| Fang TY and Baisted DJ | 2,3-Oxidosqualene cyclase and cycloartenol-s-adenosylmethionine methyltransferase activities in vivo in the cotyledon and axis tissues of germinating pea seeds. | 1975 | Biochem. J. | pmid:1212194 |
| Swift IE and Milborrow BV | Stereochemistry of allene biosynthesis and the formation of the acetylenic carotenoid diadinoxanthin and peridinin (C37) from neoxanthin. | 1981 | Biochem. J. | pmid:7337715 |
| Jayaram M and Raman TS | Metabolism of ergosterol in the larva of the rice moth (Corcyra cephalonica St.). | 1972 | Biochem. J. | pmid:5085614 |
| Nave JF et al. | Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate. | 1985 | Biochem. J. | pmid:2986604 |
| Moshier SE and Chapman DJ | Biosynthetic studies on aromatic carotenoids. Biosynthesis of chlorobactene. | 1973 | Biochem. J. | pmid:4774401 |
| McDermott JC et al. | Carotenoid biosynthesis in a Flavobacterium sp.: stereochemistry of hydrogen elimination in the desaturation of phytoene to lycopene, rubixanthin and zeaxanthin. | 1973 | Biochem. J. | pmid:4762756 |
| Goodwin TW | Recent developments in the study of the biosynthesis of carotenoids. | 1972 | Biochem. J. | pmid:5085548 |
| Mitropoulos KA and Myant NB | Evidence that the oxidation of the side chain of cholesterol by liver mitochondria is stereospecific, and that the immediate product of cleavage is propionate. | 1965 | Biochem. J. | pmid:5881647 |
| Hornby GM and Boyd GS | The origin of lanosta-7,24-dienol in rat skin. | 1971 | Biochem. J. | pmid:5131739 |
| Richards JB et al. | Dolichol phosphates as acceptors of mannose from guanosine diphosphate mannose in liver systems. | 1971 | Biochem. J. | pmid:5131017 |
| Baisted DJ | Sterol and triterpene synthesis in the developing and germinating pea seed. | 1971 | Biochem. J. | pmid:5158507 |
| Skilleter DN and Kekwick RG | The enzymes forming isopentenyl pyrophosphate from 5-phosphomevalonate (mevalonate 5-phosphate) in the latex of Hevea brasiliensis. | 1971 | Biochem. J. | pmid:4333851 |
| Milborrow BV and Noddle RC | Conversion of 5-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-methylpenta-cis-2-trans-4-dienoic acid into abscisic acid in plants. | 1970 | Biochem. J. | pmid:5493506 |
| Green TR and Baisted DJ | Development of the squalene-synthesizing system during early stages of pea seed germination. | 1971 | Biochem. J. | pmid:4335540 |
| Bolger LM et al. | Biosynthesis of 24-ethylcholesta-5,22,25-trien-3-beta-ol, a new sterol from Clerodendrum campbellii. | 1970 | Biochem. J. | pmid:5472151 |
| Ginger ML et al. | Elucidation of carbon sources used for the biosynthesis of fatty acids and sterols in the trypanosomatid Leishmania mexicana. | 1999 | Biochem. J. | pmid:10455027 |
| Gough DP et al. | The characterization of undecaprenol of Lactobacillus plantarum. | 1970 | Biochem. J. | pmid:5472148 |
| Olson RJ et al. | Alterations in cholesterol and fatty acid biosynthesis in rat liver homogenates by aryloxy acids. | 1974 | Biochem. J. | pmid:4441387 |
| Atkin SD et al. | The isolation of 2,3-oxidosqualene from the liver of rats treated with 1-dodecylimidazole, a novel hypocholesterolaemic agent. | 1972 | Biochem. J. | pmid:4655417 |
| De Souza NJ et al. | Studies on insect moulting hormones: biosynthesis of ponasterone A and ecdysterone from [2-14C] mevalonate in Taxus baccata. | 1969 | Biochem. J. | pmid:5343810 |
| Bolger LM et al. | Incorporation of [2-14C] mevalonic acid into 28-isofucosterol by leaves of Pisum sativum. | 1969 | Biochem. J. | pmid:5343809 |
| Hepper CM and Audley BG | Th biosynthesis of rubber from beta-hydroxy-beta-methylgluarylcoenzyme A in Hevea brasiliensis latex. | 1969 | Biochem. J. | pmid:4390212 |
| Buggy MJ et al. | Stereochemistry of phytoene biosynthesis by isolated chloroplasts. | 1969 | Biochem. J. | pmid:4309532 |
| Robinson DR and Ryback G | Incorporation of tritium from [(4R)-4-3H]mevalonate into abscisic acid. | 1969 | Biochem. J. | pmid:5821014 |
| Rees HH et al. | Studies in phytosterol biosynthesis. Mechanism of biosynthesis of cycloartenol. | 1968 | Biochem. J. | pmid:4297048 |
| West CA | Gibberellins and their biosynthesis. | 1969 | Biochem. J. | pmid:5810062 |
| Francis MJ and Allcock C | Monoterpene beta-D-glucosides in roses: isolation and formation from DL-2-14C mevalonate. | 1969 | Biochem. J. | pmid:5807204 |
| Reid WW | Effect of SKF7997 and SKF525 on diterpene and sterol biosynthesis in Gibberella fujikori from [2-14C] mevalonate. | 1969 | Biochem. J. | pmid:5807203 |
| Gray JC and Kekwick RG | Mevalonate kinase from etiolated cotyledons of French beans. | 1969 | Biochem. J. | pmid:5807202 |
| Goto T et al. | Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. | 2011 | Biochem. J. | pmid:21605082 |
| Austin DG et al. | Trisporic acid biosynthesis and carotenogenesis in Blakesleea trispora. | 1969 | Biochem. J. | pmid:5807198 |
| Hill HM and Rogers LJ | Conversion of lycopene into beta-carotene by chloroplasts of higher plants. | 1969 | Biochem. J. | pmid:5807194 |
| Cornforth JW and Cornforth RH | Chemistry of mevalonic acid. | 1969 | Biochem. J. | pmid:5807184 |
| Rudney H | The biosynthesis of terpenoid quinones. | 1969 | Biochem. J. | pmid:4308944 |
| Liuzzi A and Foppen FH | Sterol-like compound from sensory ganglia. Effect of a nerve growth factor and insulin on its biosynthesis. | 1968 | Biochem. J. | pmid:5641875 |
| Williams RJ et al. | The biosynthesis of cyclic carotenes. | 1967 | Biochem. J. | pmid:6060456 |
| Wieckowski S and Goodwin TW | Incorporation of DL-[2-14C]mevalonic acid lactone into beta-carotene and the phytol side chain of chlorophyll in cotyledons of four species of pine seedlings. | 1967 | Biochem. J. | pmid:6060454 |
| Gough DP and Hemming FW | The stereochemistry of betulaprenol biosynthesis. | 1967 | Biochem. J. | pmid:6056617 |
| Atkin SD et al. | The role of cytochrome P-450 in cholesterol biogenesis and catabolism. | 1972 | Biochem. J. | pmid:5084788 |
| Williams RJ et al. | The stereospecific biosynthesis of phytoene and polyunsaturated carotenes. | 1967 | Biochem. J. | pmid:6049923 |
| Rodwell VW | Cholesterol regulation of hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1972 | Biochem. J. | pmid:5085556 |
| Rees HH et al. | The biosynthesis of beta-amyrin. Mechanism of squalene cyclization. | 1968 | Biochem. J. | pmid:5639923 |
| Rogers LJ et al. | Mevalonate-kinase isoenzymes in plant cells. | 1966 | Biochem. J. | pmid:5968528 |
| Goad LJ and Goodwin TW | The biosynthesis of sterols in higher plants. | 1966 | Biochem. J. | pmid:5964970 |
| Rees HH et al. | The stereospecific biosynthesis of plant sterols and alpha- and beta-amyrin. | 1966 | Biochem. J. | pmid:5964969 |
| Rogers LJ et al. | Intracellular localization of mevalonate-activating enzymes in plant cells. | 1966 | Biochem. J. | pmid:5947149 |
| Treharne KJ et al. | Incorporation of [14C] carbon dioxide and [2-14C] mevalonic acid into terpenoids of higher plants during chloroplast development. | 1966 | Biochem. J. | pmid:5965341 |
| Fears R | The contribution of the cholesterol biosynthetic pathway to intermediary metabolism and cell function. | 1981 | Biochem. J. | pmid:7039614 |
| Thorne KJ and Kodicek E | The structure of bactoprenol, a lipid formed by lactobacilli from mevalonic acid. | 1966 | Biochem. J. | pmid:5965329 |
| Overton KH and Roberts FM | Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata. | 1974 | Biochem. J. | pmid:4468823 |
| Molowa DT and Cimis GM | Co-ordinate regulation of low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase and synthase gene expression in HepG2 cells. | 1989 | Biochem. J. | pmid:2569863 |
| Shama Bhat C and Ramasarma T | Inhibition of rat liver mevalonate pyrophosphate decarboxylase and mevalonate phosphate kinase by phenyl and phenolic compounds. | 1979 | Biochem. J. | pmid:226078 |
| Gavigan SJ and Knight BL | The effects of low-density lipoprotein and cholesterol on acyl-coenzyme A: cholesterol acyltransferase activity in membranes from cultured human fibroblasts. | 1983 | Biochem. J. | pmid:6651782 |
| Campos N et al. | Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. | 2001 | Biochem. J. | pmid:11115399 |
| Milborrow BV | Stereochemical aspects of the formation of double bonds in abscisic acid. | 1972 | Biochem. J. | pmid:4643698 |
| RAMASARMA T and RAMAKRISHNAN T | Incorporation of [2-14C]mevalonic acid and [2-14C]acetic acid into lipids of mycobacteria. | 1961 | Biochem. J. | pmid:14038591 |
| BRAITHWAITE GD and GOODWIN TW | Studies in carotenogenesis. 27. Incorporation of [2-14C] acetate, DL-[2-14C] mevalonate and C14-labelled carbon dioxide into carrotroot preparations. | 1960 | Biochem. J. | pmid:13849153 |
| BRAITHWAITE GD and GOODWIN TW | Studies in carotenogenesis. 26. The incorporation of [C14] acetate, [C14] mevalonate and C14-labelled carbon dioxide into beta-carotene by the fungus Phycomyces blakesleeanus. | 1960 | Biochem. J. | pmid:13849152 |
| Knöss W et al. | Biosynthesis of the labdane diterpene marrubiin in Marrubium vulgare via a non-mevalonate pathway. | 1997 | Biochem. J. | pmid:9291117 |
| Disch A et al. | Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. | 1998 | Biochem. J. | pmid:9531505 |
| Goad LJ | Sterol biosynthesis. | 1969 | Biochem. J. | pmid:5807186 |
| Percy-Robb IW and Boyd GS | The synthesis of bile acids in perfused rat liver subjected to chronic biliary drainage. | 1970 | Biochem. J. | pmid:5472179 |
| Goad LJ et al. | Incorporation of (2-14C, (5r)-5-3H1) mevalonic acid into cholesterol by a rat liver homogenate and into beta-sitosterol and 28-isofucosterol by larix decidua leaves. | 1969 | Biochem. J. | pmid:5348842 |
| Wade DP et al. | Independent regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and chylomicron remnant receptor activities in rat liver. | 1984 | Biochem. J. | pmid:6324750 |
| Thorne KJ | Incorporation of radioactive mevalonate into C50 and C55 phenols by Streptococcus mutans. | 1973 | Biochem. J. | pmid:4772282 |
| Derksen A et al. | Non-human primate platelets and arterial tissue cannot convert preformed [14C]lanosterol into[14C]cholesterol in vivo. | 1976 | Biochem. J. | pmid:822845 |
| Goodwin TW and Williams RJ | A mechanism for the biosynthesis of alpha-carotene. | 1965 | Biochem. J. | pmid:5881648 |
| Scharf SS and Simpson KL | Attempts to detect lycopersene formation in yeast. | 1968 | Biochem. J. | pmid:5753091 |
| Booth R et al. | The effect of dietary cholesterol on cholesterol biosynthesis and other processes in mammalian liver. | 1971 | Biochem. J. | pmid:5124798 |