| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ye J | Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus. | 2007 | PLoS Pathog. | pmid:17784784 |
| Saijonmaa O et al. | Atorvastatin inhibits angiotensin-converting enzyme induction in differentiating human macrophages. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17158648 |
| Honda A et al. | Highly sensitive assay of HMG-CoA reductase activity by LC-ESI-MS/MS. | 2007 | J. Lipid Res. | pmid:17272831 |
| Hao M et al. | Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic beta-cell dysfunction. | 2007 | Diabetes | pmid:17575085 |
| Bretón MartÃnez JR et al. | Mevalonic aciduria: report of two cases. | 2007 | J. Inherit. Metab. Dis. | pmid:17578678 |
| Ben-Tal Cohen E et al. | Statins decrease TNF-alpha-induced osteoprotegerin production by endothelial cells and smooth muscle cells in vitro. | 2007 | Biochem. Pharmacol. | pmid:17070781 |
| Igarashi J et al. | Statins induce S1P1 receptors and enhance endothelial nitric oxide production in response to high-density lipoproteins. | 2007 | Br. J. Pharmacol. | pmid:17220911 |
| Parsons RB et al. | A specific inhibitor of cholesterol biosynthesis, BM15.766, reduces the expression of beta-secretase and the production of amyloid-beta in vitro. | 2007 | J. Neurochem. | pmid:17472704 |
| Araki S et al. | Simvastatin enhances induction of inducible nitric oxide synthase in 3T3-L1 adipocytes. | 2007 | Free Radic. Res. | pmid:17729120 |
| Hargreaves IP | Coenzyme Q10 in phenylketonuria and mevalonic aciduria. | 2007 | Mitochondrion | pmid:17442628 |
| Kettawan A et al. | Protective effects of coenzyme q(10) on decreased oxidative stress resistance induced by simvastatin. | 2007 | J Clin Biochem Nutr | pmid:18398496 |
| Ferri N et al. | Simvastatin reduces MMP1 expression in human smooth muscle cells cultured on polymerized collagen by inhibiting Rac1 activation. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17303772 |
| Li M et al. | Inhibition of serotonin-induced mitogenesis, migration, and ERK MAPK nuclear translocation in vascular smooth muscle cells by atorvastatin. | 2007 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:17545489 |
| Ohyama K et al. | Chemical phenotypes of the hmg1 and hmg2 mutants of Arabidopsis demonstrate the in-planta role of HMG-CoA reductase in triterpene biosynthesis. | 2007 | Chem. Pharm. Bull. | pmid:17917299 |
| Muñoz-Bertomeu J et al. | Up-regulation of an N-terminal truncated 3-hydroxy-3-methylglutaryl CoA reductase enhances production of essential oils and sterols in transgenic Lavandula latifolia. | 2007 | Plant Biotechnol. J. | pmid:17714440 |
| Nakao T et al. | Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling. | 2007 | J. Pharmacol. Sci. | pmid:18057776 |
| Ali F et al. | Statin-mediated cytoprotection of human vascular endothelial cells: a role for Kruppel-like factor 2-dependent induction of heme oxygenase-1. | 2007 | J. Thromb. Haemost. | pmid:17927807 |
| Arkwright PD et al. | Mevalonic aciduria cured by bone marrow transplantation. | 2007 | N. Engl. J. Med. | pmid:17898110 |
| Zeiser R et al. | Preemptive HMG-CoA reductase inhibition provides graft-versus-host disease protection by Th-2 polarization while sparing graft-versus-leukemia activity. | 2007 | Blood | pmid:17827390 |
| Niknejad N et al. | Activation of the integrated stress response regulates lovastatin-induced apoptosis. | 2007 | J. Biol. Chem. | pmid:17699156 |
| Kotamraju S et al. | Statin-induced breast cancer cell death: role of inducible nitric oxide and arginase-dependent pathways. | 2007 | Cancer Res. | pmid:17671209 |
| Ostrowski SM et al. | Statins reduce amyloid-beta production through inhibition of protein isoprenylation. | 2007 | J. Biol. Chem. | pmid:17646164 |
| Hu WL et al. | Decreased C-reactive protein-induced resistin production in human monocytes by simvastatin. | 2007 | Cytokine | pmid:18023360 |
| Neven B et al. | Allogeneic bone marrow transplantation in mevalonic aciduria. | 2007 | N. Engl. J. Med. | pmid:17596604 |
| Wong WW et al. | Determinants of sensitivity to lovastatin-induced apoptosis in multiple myeloma. | 2007 | Mol. Cancer Ther. | pmid:17575117 |
| Kutrzeba L et al. | Biosynthesis of salvinorin A proceeds via the deoxyxylulose phosphate pathway. | 2007 | Phytochemistry | pmid:17574635 |
| Lopes AA et al. | Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae). | 2007 | Phytochemistry | pmid:17574633 |
| D'Amico L et al. | A mutation in zebrafish hmgcr1b reveals a role for isoprenoids in vertebrate heart-tube formation. | 2007 | Curr. Biol. | pmid:17276918 |
| Nodari S et al. | The combination of Ezetimibe and Statin: a new treatment for hypercholesterolemia. | 2007 | Heart Int | pmid:21977270 |
| Henriksson LM et al. | Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis. | 2007 | J. Biol. Chem. | pmid:17491006 |
| Dietzen DJ et al. | Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase blunts factor VIIa/tissue factor and prothrombinase activities via effects on membrane phosphatidylserine. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17185615 |
| Nakata S et al. | Statin treatment upregulates vascular neuronal nitric oxide synthase through Akt/NF-kappaB pathway. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17082483 |
| Loiseau L et al. | ErpA, an iron sulfur (Fe S) protein of the A-type essential for respiratory metabolism in Escherichia coli. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17698959 |
| Mönkkönen H et al. | Zoledronic acid-induced IPP/ApppI production in vivo. | 2007 | Life Sci. | pmid:17850825 |
| Withers ST et al. | Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. | 2007 | Appl. Environ. Microbiol. | pmid:17693564 |
| Buhaescu I and Izzedine H | Mevalonate pathway: a review of clinical and therapeutical implications. | 2007 | Clin. Biochem. | pmid:17467679 |
| März P et al. | Statins induce differentiation and cell death in neurons and astroglia. | 2007 | Glia | pmid:16998865 |
| Riganti C et al. | Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition. | 2007 | Am. J. Respir. Cell Mol. Biol. | pmid:17322126 |
| Habib A et al. | Modulation of COX-2 expression by statins in human monocytic cells. | 2007 | FASEB J. | pmid:17317725 |
| Pertusa M et al. | Transcriptional control of cholesterol biosynthesis in Schwann cells by axonal neuregulin 1. | 2007 | J. Biol. Chem. | pmid:17652086 |
| Jantzen F et al. | Isoprenoid depletion by statins antagonizes cytokine-induced down-regulation of endothelial nitric oxide expression and increases NO synthase activity in human umbilical vein endothelial cells. | 2007 | J. Physiol. Pharmacol. | pmid:17928646 |
| Nakajima H et al. | Induction of mitochondria-dependent apoptosis through the inhibition of mevalonate pathway in human breast cancer cells by YM529, a new third generation bisphosphonate. | 2007 | Cancer Lett. | pmid:17316980 |
| Takahashi HK et al. | Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction. | 2007 | Clin. Immunol. | pmid:17482516 |
| Bock O et al. | Common musculoskeletal adverse effects of oral treatment with once weekly alendronate and risedronate in patients with osteoporosis and ways for their prevention. | 2007 Apr-Jun | J Musculoskelet Neuronal Interact | pmid:17627083 |
| Matsunaga S et al. | Incadronate induces cell detachment and apoptosis in prostatic PC-3 cells. | 2007 Mar-Apr | Anticancer Res. | pmid:17465222 |
| Yoon SH et al. | Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. | 2007 May-Jun | Biotechnol. Prog. | pmid:17500531 |
| Lazzerini PE et al. | Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients. | 2007 Sep-Oct | Clin. Exp. Rheumatol. | pmid:18078616 |
| Ogunwobi OO and Beales IL | Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. | 2008 | Am. J. Gastroenterol. | pmid:18371146 |
| Kimura T et al. | Induction of scavenger receptor class B type I is critical for simvastatin enhancement of high-density lipoprotein-induced anti-inflammatory actions in endothelial cells. | 2008 | J. Immunol. | pmid:18981156 |
| Kotti T et al. | Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18685105 |
| Rekittke I et al. | Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. | 2008 | J. Am. Chem. Soc. | pmid:19035630 |
| Saito E et al. | 7-ketocholesterol, a major oxysterol, promotes pi-induced vascular calcification in cultured smooth muscle cells. | 2008 | J. Atheroscler. Thromb. | pmid:18603819 |
| Grigore L et al. | Combination therapy in cholesterol reduction: focus on ezetimibe and statins. | 2008 | Vasc Health Risk Manag | pmid:18561502 |
| Sharyo S et al. | Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway. | 2008 | Kidney Int. | pmid:18509318 |
| Kervizic G and Corcos L | Dynamical modeling of the cholesterol regulatory pathway with Boolean networks. | 2008 | BMC Syst Biol | pmid:19025648 |
| Tekle M et al. | Investigation of coenzyme Q biosynthesis in human fibroblast and HepG2 cells. | 2008 | J. Biochem. Biophys. Methods | pmid:17916383 |
| Cornish J et al. | Modulation of osteoclastogenesis by fatty acids. | 2008 | Endocrinology | pmid:18617622 |
| Okada K et al. | Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. | 2008 | Plant Cell Physiol. | pmid:18303110 |
| Lüdke SM et al. | Stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 2008 | J. Lipid Res. | pmid:18669481 |
| Winiarska M et al. | Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. | 2008 | PLoS Med. | pmid:18366248 |
| Oliveira KA et al. | Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction. | 2008 | J. Bioenerg. Biomembr. | pmid:18679777 |
| Abumweis SS et al. | Plant sterols/stanols as cholesterol lowering agents: A meta-analysis of randomized controlled trials. | 2008 | Food Nutr Res | pmid:19109655 |
| Sapir-Mir M et al. | Peroxisomal localization of Arabidopsis isopentenyl diphosphate isomerases suggests that part of the plant isoprenoid mevalonic acid pathway is compartmentalized to peroxisomes. | 2008 | Plant Physiol. | pmid:18988695 |
| Sławińska A and Kandefer-Szerszeń M | [The anticancer properties of statins]. | 2008 | Postepy Hig Med Dosw (Online) | pmid:18688209 |
| Acharjee S and Welty FK | Atorvastatin and cardiovascular risk in the elderly--patient considerations. | 2008 | Clin Interv Aging | pmid:18686752 |
| Journe F et al. | Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. | 2008 | Breast Cancer Res. Treat. | pmid:17333335 |
| Sando T et al. | Cloning and characterization of mevalonate pathway genes in a natural rubber producing plant, Hevea brasiliensis. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18685207 |
| Laezza C et al. | The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway. | 2008 | Endocr. Relat. Cancer | pmid:18676619 |
| Bate C et al. | Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells. | 2008 | BMC Biol. | pmid:18789130 |
| Kistowska M et al. | Dysregulation of the host mevalonate pathway during early bacterial infection activates human TCR gamma delta cells. | 2008 | Eur. J. Immunol. | pmid:18624305 |
| Matsuda T et al. | Simvastatin inhibits catecholamine secretion and synthesis induced by acetylcholine via blocking Na+ and Ca2+ influx in bovine adrenal medullary cells. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18593956 |
| Habara K et al. | Pitavastatin up-regulates the induction of iNOS through enhanced stabilization of its mRNA in pro-inflammatory cytokine-stimulated hepatocytes. | 2008 | Nitric Oxide | pmid:17936042 |
| Fried LF | Effects of HMG-CoA reductase inhibitors (statins) on progression of kidney disease. | 2008 | Kidney Int. | pmid:18528321 |
| Skorupinska-Tudek K et al. | Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. | 2008 | J. Biol. Chem. | pmid:18502754 |
| Zhang X et al. | Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. | 2008 | J. Immunol. | pmid:18453621 |
| Aprigliano I et al. | Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells. | 2008 | Liver Int. | pmid:18339080 |
| Burke LP and Kukoly CA | Statins induce lethal effects in acute myeloblastic leukemia [corrected] cells within 72 hours. | 2008 | Leuk. Lymphoma | pmid:18231920 |
| Glynn SA et al. | The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. | 2008 | BMC Cancer | pmid:18199328 |
| Galichet A et al. | Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. | 2008 | Plant Physiol. | pmid:18184738 |
| Kodaman PH and Duleba AJ | Statins in the treatment of polycystic ovary syndrome. | 2008 | Semin. Reprod. Med. | pmid:18181091 |
| Wilson GJ et al. | Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review. | 2008 | Nutr Metab (Lond) | pmid:18173841 |
| Mathew B and Biju R | Neuroprotective effects of garlic a review. | 2008 | Libyan J Med | pmid:21499478 |
| Yoshida T et al. | Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. | 2008 | Anal Chem Insights | pmid:19609389 |
| Saito A et al. | Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells. | 2008 | Melanoma Res. | pmid:18337644 |
| Baba TT et al. | Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway. | 2008 | J. Muscle Res. Cell. Motil. | pmid:18792797 |
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| Martin-Ventura JL et al. | LDL induces parathyroid hormone-related protein expression in vascular smooth muscle cells: Modulation by simvastatin. | 2008 | Atherosclerosis | pmid:18378243 |
| Park SY et al. | Inhibitory effect of simvastatin on the TNF-alpha- and angiotensin II-induced monocyte adhesion to endothelial cells is mediated through the suppression of geranylgeranyl isoprenoid-dependent ROS generation. | 2008 | Arch. Pharm. Res. | pmid:18365690 |
| Begley M et al. | Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection. | 2008 | Infect. Immun. | pmid:18765739 |
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| Tarhzaoui K et al. | Effect of rosuvastatin on capillary filtration of albumin and blood pressure in rats with streptozotocin-induced diabetes. | 2008 | Diabetes Res. Clin. Pract. | pmid:18406000 |
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| Kaliszewski P et al. | Rsp5p ubiquitin ligase and the transcriptional activators Spt23p and Mga2p are involved in co-regulation of biosynthesis of end products of the mevalonate pathway and triacylglycerol in yeast Saccharomyces cerevisiae. | 2008 | Biochim. Biophys. Acta | pmid:18771750 |
| Voynova NE et al. | Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. | 2008 | Arch. Biochem. Biophys. | pmid:18823933 |
| Pscheidt B and Glieder A | Yeast cell factories for fine chemical and API production. | 2008 | Microb. Cell Fact. | pmid:18684335 |
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| Liang YJ et al. | Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products. | 2008 | Cardiology | pmid:18057884 |
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