| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ogunwobi OO and Beales IL | Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. | 2008 | Am. J. Gastroenterol. | pmid:18371146 |
| Kimura T et al. | Induction of scavenger receptor class B type I is critical for simvastatin enhancement of high-density lipoprotein-induced anti-inflammatory actions in endothelial cells. | 2008 | J. Immunol. | pmid:18981156 |
| Rekittke I et al. | Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. | 2008 | J. Am. Chem. Soc. | pmid:19035630 |
| Sharyo S et al. | Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway. | 2008 | Kidney Int. | pmid:18509318 |
| Kervizic G and Corcos L | Dynamical modeling of the cholesterol regulatory pathway with Boolean networks. | 2008 | BMC Syst Biol | pmid:19025648 |
| Udagawa H et al. | Increase of serum cholesterol levels by heat-moisture-treated high-amylose cornstarch in rats fed a high-cholesterol diet. | 2008 | Lipids | pmid:18509689 |
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| Cornish J et al. | Modulation of osteoclastogenesis by fatty acids. | 2008 | Endocrinology | pmid:18617622 |
| Okada K et al. | Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. | 2008 | Plant Cell Physiol. | pmid:18303110 |
| Lüdke SM et al. | Stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 2008 | J. Lipid Res. | pmid:18669481 |
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| Oliveira KA et al. | Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction. | 2008 | J. Bioenerg. Biomembr. | pmid:18679777 |
| Chana RS et al. | Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis. | 2008 | Am. J. Nephrol. | pmid:18535368 |
| Abumweis SS et al. | Plant sterols/stanols as cholesterol lowering agents: A meta-analysis of randomized controlled trials. | 2008 | Food Nutr Res | pmid:19109655 |
| Sapir-Mir M et al. | Peroxisomal localization of Arabidopsis isopentenyl diphosphate isomerases suggests that part of the plant isoprenoid mevalonic acid pathway is compartmentalized to peroxisomes. | 2008 | Plant Physiol. | pmid:18988695 |
| Sławińska A and Kandefer-Szerszeń M | [The anticancer properties of statins]. | 2008 | Postepy Hig Med Dosw (Online) | pmid:18688209 |
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| Journe F et al. | Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. | 2008 | Breast Cancer Res. Treat. | pmid:17333335 |
| Sando T et al. | Cloning and characterization of mevalonate pathway genes in a natural rubber producing plant, Hevea brasiliensis. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18685207 |
| Laezza C et al. | The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway. | 2008 | Endocr. Relat. Cancer | pmid:18676619 |
| Bate C et al. | Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells. | 2008 | BMC Biol. | pmid:18789130 |
| Habara K et al. | Pitavastatin up-regulates the induction of iNOS through enhanced stabilization of its mRNA in pro-inflammatory cytokine-stimulated hepatocytes. | 2008 | Nitric Oxide | pmid:17936042 |
| Fried LF | Effects of HMG-CoA reductase inhibitors (statins) on progression of kidney disease. | 2008 | Kidney Int. | pmid:18528321 |
| Skorupinska-Tudek K et al. | Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. | 2008 | J. Biol. Chem. | pmid:18502754 |
| Zhang X et al. | Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. | 2008 | J. Immunol. | pmid:18453621 |
| Aprigliano I et al. | Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells. | 2008 | Liver Int. | pmid:18339080 |
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| Burke LP and Kukoly CA | Statins induce lethal effects in acute myeloblastic leukemia [corrected] cells within 72 hours. | 2008 | Leuk. Lymphoma | pmid:18231920 |
| Glynn SA et al. | The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. | 2008 | BMC Cancer | pmid:18199328 |
| Galichet A et al. | Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. | 2008 | Plant Physiol. | pmid:18184738 |
| Kodaman PH and Duleba AJ | Statins in the treatment of polycystic ovary syndrome. | 2008 | Semin. Reprod. Med. | pmid:18181091 |
| Wilson GJ et al. | Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review. | 2008 | Nutr Metab (Lond) | pmid:18173841 |
| Mathew B and Biju R | Neuroprotective effects of garlic a review. | 2008 | Libyan J Med | pmid:21499478 |
| Yoshida T et al. | Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. | 2008 | Anal Chem Insights | pmid:19609389 |
| Saito A et al. | Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells. | 2008 | Melanoma Res. | pmid:18337644 |
| Baba TT et al. | Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway. | 2008 | J. Muscle Res. Cell. Motil. | pmid:18792797 |
| Habeos IG et al. | Simvastatin activates Keap1/Nrf2 signaling in rat liver. | 2008 | J. Mol. Med. | pmid:18787804 |
| Osman L et al. | Atorvastatin accelerates extracellular nucleotide degradation in human endothelial cells. | 2008 | Mol. Cell. Biochem. | pmid:18158588 |
| Paintlia AS et al. | Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis. | 2008 | Mol. Pharmacol. | pmid:18239032 |
| Martin-Ventura JL et al. | LDL induces parathyroid hormone-related protein expression in vascular smooth muscle cells: Modulation by simvastatin. | 2008 | Atherosclerosis | pmid:18378243 |
| Baldi A and Dixit VK | Yield enhancement strategies for artemisinin production by suspension cultures of Artemisia annua. | 2008 | Bioresour. Technol. | pmid:17804216 |
| Park SY et al. | Inhibitory effect of simvastatin on the TNF-alpha- and angiotensin II-induced monocyte adhesion to endothelial cells is mediated through the suppression of geranylgeranyl isoprenoid-dependent ROS generation. | 2008 | Arch. Pharm. Res. | pmid:18365690 |
| Begley M et al. | Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection. | 2008 | Infect. Immun. | pmid:18765739 |
| Simonen M et al. | High-content assay to study protein prenylation. | 2008 | J Biomol Screen | pmid:18509097 |
| Tarhzaoui K et al. | Effect of rosuvastatin on capillary filtration of albumin and blood pressure in rats with streptozotocin-induced diabetes. | 2008 | Diabetes Res. Clin. Pract. | pmid:18406000 |
| Zhuge B et al. | Bioconversion of lovastatin to a novel statin by Amycolatopsis sp. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18368405 |
| Voynova NE et al. | Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. | 2008 | Arch. Biochem. Biophys. | pmid:18823933 |
| Pscheidt B and Glieder A | Yeast cell factories for fine chemical and API production. | 2008 | Microb. Cell Fact. | pmid:18684335 |
| Schwartz YSh et al. | Cholesterol-induced stimulation of postinflammatory liver fibrosis. | 2008 | Bull. Exp. Biol. Med. | pmid:19110552 |
| Yu F et al. | Isolation and functional characterization of a beta-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith. | 2008 | FEBS Lett. | pmid:18242187 |
| de Ruyck J and Wouters J | Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes. | 2008 | Curr. Protein Pept. Sci. | pmid:18393884 |
| Lazzerini PE et al. | Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients. | 2007 Sep-Oct | Clin. Exp. Rheumatol. | pmid:18078616 |
| Yoon SH et al. | Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. | 2007 May-Jun | Biotechnol. Prog. | pmid:17500531 |
| Matsunaga S et al. | Incadronate induces cell detachment and apoptosis in prostatic PC-3 cells. | 2007 Mar-Apr | Anticancer Res. | pmid:17465222 |
| Bock O et al. | Common musculoskeletal adverse effects of oral treatment with once weekly alendronate and risedronate in patients with osteoporosis and ways for their prevention. | 2007 Apr-Jun | J Musculoskelet Neuronal Interact | pmid:17627083 |
| Kuroda M et al. | Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus. | 2007 | J. Antimicrob. Chemother. | pmid:17242033 |
| Tanaka T et al. | Lipophilic statins suppress cytotoxicity by freshly isolated natural killer cells through modulation of granule exocytosis. | 2007 | Int. Immunol. | pmid:17182966 |
| Nishimoto T et al. | Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17599378 |
| Hao M et al. | Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic beta-cell dysfunction. | 2007 | Diabetes | pmid:17575085 |
| Parsons RB et al. | A specific inhibitor of cholesterol biosynthesis, BM15.766, reduces the expression of beta-secretase and the production of amyloid-beta in vitro. | 2007 | J. Neurochem. | pmid:17472704 |
| Araki S et al. | Simvastatin enhances induction of inducible nitric oxide synthase in 3T3-L1 adipocytes. | 2007 | Free Radic. Res. | pmid:17729120 |
| Haas D and Hoffmann GF | Mevalonate kinase deficiency and autoinflammatory disorders. | 2007 | N. Engl. J. Med. | pmid:17596600 |
| Hargreaves IP | Coenzyme Q10 in phenylketonuria and mevalonic aciduria. | 2007 | Mitochondrion | pmid:17442628 |
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| Jahangir T and Sultana S | Perillyl Alcohol Protects Against Fe-NTA-Induced Nephrotoxicity and Early Tumor Promotional Events in Rat Experimental Model. | 2007 | Evid Based Complement Alternat Med | pmid:18227911 |
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| Hunter WN | The non-mevalonate pathway of isoprenoid precursor biosynthesis. | 2007 | J. Biol. Chem. | pmid:17442674 |
| Takeda I et al. | Simvastatin inactivates beta1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells. | 2007 | Cancer Sci. | pmid:17428261 |
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