Saha RN and Pahan K |
Regulation of inducible nitric oxide synthase gene in glial cells. |
2006 May-Jun |
Antioxid. Redox Signal. |
pmid:16771683
|
Tamura G et al. |
Production of mevalonic acid by fermentation. |
1968 |
Appl Microbiol |
pmid:5664126
|
Baadhe RR et al. |
Development of petri net-based dynamic model for improved production of farnesyl pyrophosphate by integrating mevalonate and methylerythritol phosphate pathways in yeast. |
2012 |
Appl. Biochem. Biotechnol. |
pmid:22350871
|
Wang J et al. |
Engineering of a Highly Efficient Escherichia coli Strain for Mevalonate Fermentation through Chromosomal Integration. |
2016 |
Appl. Environ. Microbiol. |
pmid:27736790
|
Hagler WM et al. |
Biosynthesis of radiolabeled T-2 toxin by Fusarium tricinctum. |
1981 |
Appl. Environ. Microbiol. |
pmid:7235702
|
Rossoni L et al. |
The Putative mevalonate diphosphate decarboxylase from Picrophilus torridus is in reality a mevalonate-3-kinase with high potential for bioproduction of isobutene. |
2015 |
Appl. Environ. Microbiol. |
pmid:25636853
|
Rico J et al. |
Enhanced production of a plant monoterpene by overexpression of the 3-hydroxy-3-methylglutaryl coenzyme A reductase catalytic domain in Saccharomyces cerevisiae. |
2010 |
Appl. Environ. Microbiol. |
pmid:20675444
|
Withers ST et al. |
Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. |
2007 |
Appl. Environ. Microbiol. |
pmid:17693564
|
Yoon SH et al. |
Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. |
2007 |
Appl. Microbiol. Biotechnol. |
pmid:17115209
|
Morrone D et al. |
Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:19777230
|
Seker T et al. |
Analysis of acyl CoA ester intermediates of the mevalonate pathway in Saccharomyces cerevisiae. |
2005 |
Appl. Microbiol. Biotechnol. |
pmid:15448940
|
Panda T and Devi VA |
Regulation and degradation of HMGCo-A reductase. |
2004 |
Appl. Microbiol. Biotechnol. |
pmid:15558272
|
Guan Z et al. |
Metabolic engineering of Bacillus subtilis for terpenoid production. |
2015 |
Appl. Microbiol. Biotechnol. |
pmid:26373726
|
Tisch D and Schmoll M |
Light regulation of metabolic pathways in fungi. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:19915832
|
Kim YS et al. |
Increase of lycopene production by supplementing auxiliary carbon sources in metabolically engineered Escherichia coli. |
2011 |
Appl. Microbiol. Biotechnol. |
pmid:21246354
|
Zhuge B et al. |
Bioconversion of lovastatin to a novel statin by Amycolatopsis sp. |
2008 |
Appl. Microbiol. Biotechnol. |
pmid:18368405
|
Mokashi V et al. |
Supernatant protein factor stimulates HMG-CoA reductase in cell culture and in vitro. |
2005 |
Arch. Biochem. Biophys. |
pmid:15581604
|
Havel CM and Watson JA |
Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute, basal mevalonate synthesis rate determination. |
1992 |
Arch. Biochem. Biophys. |
pmid:1567218
|
TSAI SC et al. |
TESTICULAR STEROLS. 1. INCORPORATION OF MEVALONATE AND ACETATE INTO STEROLS BY TESTICULAR TISSUE FROM RATS. |
1964 |
Arch. Biochem. Biophys. |
pmid:14186739
|
Li G and Stahl PD |
Post-translational processing and membrane association of the two early endosome-associated rab GTP-binding proteins (rab4 and rab5). |
1993 |
Arch. Biochem. Biophys. |
pmid:8346922
|
Faust JR et al. |
Synthesis of ubiquinone and cholesterol in human fibroblasts: regulation of a branched pathway. |
1979 |
Arch. Biochem. Biophys. |
pmid:219777
|
Vaidya S et al. |
Massive production of farnesol-derived dicarboxylic acids in mice treated with the squalene synthase inhibitor zaragozic acid A. |
1998 |
Arch. Biochem. Biophys. |
pmid:9647670
|
Merola AJ et al. |
Effects of estrogens on cholesterol biosynthesis and tissue distribution in rats. |
1968 |
Arch. Biochem. Biophys. |
pmid:5642605
|
Bergstrom JD et al. |
Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase. |
2000 |
Arch. Biochem. Biophys. |
pmid:10620343
|
Peffley DM and Gayen AK |
Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level. |
1997 |
Arch. Biochem. Biophys. |
pmid:9016820
|
Borgford TJ et al. |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and lipid metabolism in a concanavalin A-resistant Chinese hamster ovary cell line. |
1986 |
Arch. Biochem. Biophys. |
pmid:3947077
|
Moir NJ et al. |
Effect of cholestyramine on the terminal reactions of sterol biosynthesis. |
1970 |
Arch. Biochem. Biophys. |
pmid:4395692
|
Kabakoff BD et al. |
Relationships among dolichyl phosphate, glycoprotein synthesis, and cell culture growth. |
1990 |
Arch. Biochem. Biophys. |
pmid:2407191
|
Terabe K et al. |
Simvastatin inhibits CD44 fragmentation in chondrocytes. |
2016 |
Arch. Biochem. Biophys. |
pmid:27242325
|
Back P et al. |
Regulation of cholesterol biosynthesis in rat liver: diurnal changes of activity and influence of bile acids. |
1969 |
Arch. Biochem. Biophys. |
pmid:5810824
|
Meigs TE and Simoni RD |
Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase. |
1997 |
Arch. Biochem. Biophys. |
pmid:9281305
|
Krishnaiah KV et al. |
Effect of dietary cholesterol and ubiquinone on isoprene synthesis in rat liver. |
1967 |
Arch. Biochem. Biophys. |
pmid:6035059
|
Gonzalez R et al. |
Two major regulatory steps in cholesterol synthesis by human renal cancer cells. |
1979 |
Arch. Biochem. Biophys. |
pmid:485166
|
Beg ZH et al. |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts by reversible phosphorylation: modulation of enzymatic activity by low density lipoprotein, sterols, and mevalonolactone. |
1986 |
Arch. Biochem. Biophys. |
pmid:3004340
|
Miziorko HM |
Enzymes of the mevalonate pathway of isoprenoid biosynthesis. |
2011 |
Arch. Biochem. Biophys. |
pmid:20932952
|
Rilling HC et al. |
Differential prenylation of proteins as a function of mevalonate concentration in CHO cells. |
1993 |
Arch. Biochem. Biophys. |
pmid:8460935
|
FUMAGALLI R et al. |
Cholesterol synthesis in rat brain: differential incorporation of mevalonolactone-2-C14 and potassium mevalonate-2-C14. |
1962 |
Arch. Biochem. Biophys. |
pmid:13960261
|
Craig MC et al. |
Comparative effects of dietary regimens on the levels of enzymes regulating the synthesis of fatty acids and cholesterol in rat liver. |
1972 |
Arch. Biochem. Biophys. |
pmid:5044513
|
PORTMAN OW and SUGANO M |
THE HYDROLYSIS AND FATTY ACID EXCHANGE OF CHOLESTEROL ESTERS ADMINISTERED IN LIPOPROTEINS TO CEBUS MONKEYS. |
1963 |
Arch. Biochem. Biophys. |
pmid:14072510
|
Appelkvist EL et al. |
Presence of individual enzymes of cholesterol biosynthesis in rat liver peroxisomes. |
1990 |
Arch. Biochem. Biophys. |
pmid:2241153
|
Schulte AE et al. |
Purification and characterization of mevalonate kinase from suspension-cultured cells of Catharanthus roseus (L.) G. Don. |
2000 |
Arch. Biochem. Biophys. |
pmid:10860546
|
Adam KP et al. |
Involvement of the mevalonic acid pathway and the glyceraldehyde-pyruvate pathway in terpenoid biosynthesis of the liverworts Ricciocarpos natans and Conocephalum conicum. |
1998 |
Arch. Biochem. Biophys. |
pmid:9633614
|
Parmryd I and Dallner G |
In vivo prenylation of rat proteins: modification of proteins with penta- and hexaprenyl groups. |
1999 |
Arch. Biochem. Biophys. |
pmid:10190969
|
Skaff DA et al. |
Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds. |
2015 |
Arch. Biochem. Biophys. |
pmid:25499551
|
Shimizu S et al. |
Possible involvement of 3-hydroxymethylglutaryl-CoA reductase in determining the side-chain length of ubiquinone in rat heart. |
1991 |
Arch. Biochem. Biophys. |
pmid:1846516
|
GAYLOR JL |
Biosynthesis of skin sterols. V. Effect of arsenite inhibition and the accumulation of labeled lanosta-7, 24-dien-3 beta-ol in rat skin. |
1963 |
Arch. Biochem. Biophys. |
pmid:13946925
|
BEELER DA et al. |
The biosynthesis of squalene from mevalonic acid-2-C-14 and farnesyl pyrophosphate-4,8,12-C-14 by carrot and tomato enzymes. |
1963 |
Arch. Biochem. Biophys. |
pmid:13970235
|
Hulcher FH |
Inhibition of hepatic cholesterol biosynthesis by 3,5-dihydroxy-3,4,4-trimethylvaleric acid and its site of action. |
1971 |
Arch. Biochem. Biophys. |
pmid:5114913
|
Nepokroeff CM et al. |
Regulation of the diurnal rhythm of rat liver beta-hydroxy-beta-methylglutaryl coenzmye A reductase activity by insulin, glucagon, cyclic AMP and hydrocortisone. |
1974 |
Arch. Biochem. Biophys. |
pmid:4364764
|
Yamamoto T et al. |
Identification of regulatory sites in the biosynthesis of ubiquinone in the perfused rat heart. |
1989 |
Arch. Biochem. Biophys. |
pmid:2916849
|
Muroya H et al. |
Stimulation of hepatic cholesterol biosynthesis by dietary glucose, and its relation to cholesterol gallstone formation in the hamster. |
1968 |
Arch. Biochem. Biophys. |
pmid:5661591
|
GARATTINI S et al. |
Lipid biosynthesis in vivo from acetate-1-C 14 and 2-C 14 and mevalonic-2-C 14 acid. |
1959 |
Arch. Biochem. Biophys. |
pmid:13826357
|
SHAH SN et al. |
The effect of growth hormone administration and dietary protein on the incorporation of sodium acetate-2-C14 and mevalonic acid-2-C14 into liver cholesterol. |
1961 |
Arch. Biochem. Biophys. |
pmid:13750592
|
Edwards PA |
The influence of catecholamines and cyclic AMP on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and lipid biosynthesis in isolated rat hepatocytes. |
1975 |
Arch. Biochem. Biophys. |
pmid:169744
|
Straka MS and Panini SR |
Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate. |
1995 |
Arch. Biochem. Biophys. |
pmid:7872789
|
Giron MD et al. |
Isopentenoid synthesis in eukaryotic cells. An initiating role for post-translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. |
1993 |
Arch. Biochem. Biophys. |
pmid:8097083
|
Godinez MH et al. |
The biosynthesis of isoprenoid lipids including ubiquinone in muscle from normal and genetically dystrophic mice. |
1970 |
Arch. Biochem. Biophys. |
pmid:5460184
|
Gayen AK and Peffley DM |
The length of 5'-untranslated leader sequences influences distribution of 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in polysomes: effects of lovastatin, oxysterols, and mevalonate. |
1995 |
Arch. Biochem. Biophys. |
pmid:7574724
|
Ness GC et al. |
Effect of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7 alpha hydroxylase. |
1994 |
Arch. Biochem. Biophys. |
pmid:7911291
|
Jedlicki E et al. |
Stereospecificity of isopentenylpyrophosphate isomerase and prenyl transferase from pinus and citrus. |
1972 |
Arch. Biochem. Biophys. |
pmid:4635785
|
Howe EE et al. |
The hypolipemic properties of 5 beta-cholanic acid in the mouse and rat. |
1969 |
Arch. Biochem. Biophys. |
pmid:5773747
|
Jacobsohn GM and Frey MJ |
Sterol content and metabolism during early growth of Digitalis purpurea. |
1968 |
Arch. Biochem. Biophys. |
pmid:5698012
|
Keller RK et al. |
Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. |
1996 |
Arch. Biochem. Biophys. |
pmid:8645011
|
Kandutsch AA and Packie RM |
Comparison of the effects of some C27-, C21-, and C19-steroids upon hepatic sterol synthesis and hydroxymethylglutaryl-CoA reductase activity. |
1970 |
Arch. Biochem. Biophys. |
pmid:5460174
|
Voynova NE et al. |
Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. |
2008 |
Arch. Biochem. Biophys. |
pmid:18823933
|
Andres DA et al. |
Expression cloning of a novel farnesylated protein, RDJ2, encoding a DnaJ protein homologue. |
1997 |
Arch. Biochem. Biophys. |
pmid:9328291
|
Butterworth PH et al. |
In vivo incorporation of [2-14-C]-mevalonate into dolichol of rabbit and pig liver. |
1966 |
Arch. Biochem. Biophys. |
pmid:5944963
|
Ranganathan S et al. |
The biosynthesis of ubiquinone in isolated rat heart cells. |
1979 |
Arch. Biochem. Biophys. |
pmid:518096
|
Vögeli U and Chappell J |
Inhibition of a plant sesquiterpene cyclase by mevinolin. |
1991 |
Arch. Biochem. Biophys. |
pmid:1898013
|
SUGANO M and PORTMAN OW |
FATTY ACID SPECIFICITIES AND RATES OF CHOLESTEROL ESTERIFICATION IN VIVO AND IN VITRO. |
1964 |
Arch. Biochem. Biophys. |
pmid:14224844
|
Dugan RE et al. |
Regulation of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A reductase by the interplay of hormones. |
1974 |
Arch. Biochem. Biophys. |
pmid:4275665
|
Frenkel J et al. |
Increased urinary leukotriene E(4) during febrile attacks in the hyperimmunoglobulinaemia D and periodic fever syndrome. |
2001 |
Arch. Dis. Child. |
pmid:11466192
|
Raupp P et al. |
Novel genotype of mevalonic aciduria with fatalities in premature siblings. |
2004 |
Arch. Dis. Child. Fetal Neonatal Ed. |
pmid:14711867
|
Kuzina V et al. |
Relationships among the biosyntheses of ubiquinone, carotene, sterols, and triacylglycerols in Zygomycetes. |
2006 |
Arch. Microbiol. |
pmid:17009023
|
Hindy AM et al. |
Sterol composition and biosynthesis in mouse salivary glands. |
1986 |
Arch. Oral Biol. |
pmid:3460541
|
Park SY et al. |
Inhibitory effect of simvastatin on the TNF-alpha- and angiotensin II-induced monocyte adhesion to endothelial cells is mediated through the suppression of geranylgeranyl isoprenoid-dependent ROS generation. |
2008 |
Arch. Pharm. Res. |
pmid:18365690
|
Jarrell KF et al. |
S-layer glycoproteins and flagellins: reporters of archaeal posttranslational modifications. |
2010 |
Archaea |
pmid:20721273
|
Harada-Shiba M et al. |
Siblings with normal LDL receptor activity and severe hypercholesterolemia. |
1992 |
Arterioscler. Thromb. |
pmid:1525122
|
Wagner AH et al. |
3-hydroxy-3-methylglutaryl coenzyme A reductase-independent inhibition of CD40 expression by atorvastatin in human endothelial cells. |
2002 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12426205
|
Kwiterovich PO and Motevalli M |
Differential effect of genistein on the stimulation of cholesterol production by basic protein II in normal and hyperapoB fibroblasts. |
1998 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:9445257
|
Ichiki T et al. |
Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11742861
|
Diomede L et al. |
In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11498461
|
Yasunari K et al. |
HMG-CoA reductase inhibitors prevent migration of human coronary smooth muscle cells through suppression of increase in oxidative stress. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11397700
|
MartÃnez-González J et al. |
3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: balance between transcriptional and posttranscriptional regulation. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11348878
|
Loregger A et al. |
Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis. |
2017 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:28882874
|
O'Neill FH et al. |
Determinants of variable response to statin treatment in patients with refractory familial hypercholesterolemia. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11348882
|
Sakamoto K et al. |
Fluvastatin prevents vascular hyperplasia by inhibiting phenotype modulation and proliferation through extracellular signal-regulated kinase 1 and 2 and p38 mitogen-activated protein kinase inactivation in organ-cultured artery. |
2005 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15591221
|
Dubuc G et al. |
Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15178557
|
Wagner AH et al. |
Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation. |
2000 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:10634801
|
Dje N'Guessan P et al. |
Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. |
2009 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:19122173
|
Colli S et al. |
Vastatins inhibit tissue factor in cultured human macrophages. A novel mechanism of protection against atherothrombosis. |
1997 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:9081680
|
Jones PJ et al. |
Dietary cholesterol feeding suppresses human cholesterol synthesis measured by deuterium incorporation and urinary mevalonic acid levels. |
1996 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:8857917
|
Ferri N et al. |
Simvastatin reduces MMP1 expression in human smooth muscle cells cultured on polymerized collagen by inhibiting Rac1 activation. |
2007 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17303772
|
Dietzen DJ et al. |
Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase blunts factor VIIa/tissue factor and prothrombinase activities via effects on membrane phosphatidylserine. |
2007 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17185615
|
Nakata S et al. |
Statin treatment upregulates vascular neuronal nitric oxide synthase through Akt/NF-kappaB pathway. |
2007 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17082483
|
Goto D et al. |
Upregulation of low density lipoprotein receptor by gemfibrozil, a hypolipidemic agent, in human hepatoma cells through stabilization of mRNA transcripts. |
1997 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:9409246
|
Wu B et al. |
Paradoxical effects of statins on aortic valve myofibroblasts and osteoblasts: implications for end-stage valvular heart disease. |
2005 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15618546
|
Kwiterovich PO and Motevalli M |
Inhibition of protein tyrosine kinase alters the effect of serum basic protein I on triacylglycerols and cholesterol differently in normal and hyperapoB fibroblasts. |
1995 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:7627714
|
Bernini F et al. |
HMG-CoA reductase inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages. |
1995 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:7670949
|
Luan Z et al. |
Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12663370
|