Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Refsum Disease D012035 19 associated lipids
Thrombosis D013927 49 associated lipids
Xanthomatosis D014973 17 associated lipids
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

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All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Ogunwobi OO and Beales IL Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. 2008 Am. J. Gastroenterol. pmid:18371146
Kimura T et al. Induction of scavenger receptor class B type I is critical for simvastatin enhancement of high-density lipoprotein-induced anti-inflammatory actions in endothelial cells. 2008 J. Immunol. pmid:18981156
Kotti T et al. Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18685105
Rekittke I et al. Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. 2008 J. Am. Chem. Soc. pmid:19035630
Saito E et al. 7-ketocholesterol, a major oxysterol, promotes pi-induced vascular calcification in cultured smooth muscle cells. 2008 J. Atheroscler. Thromb. pmid:18603819
Grigore L et al. Combination therapy in cholesterol reduction: focus on ezetimibe and statins. 2008 Vasc Health Risk Manag pmid:18561502
Sharyo S et al. Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway. 2008 Kidney Int. pmid:18509318
Kervizic G and Corcos L Dynamical modeling of the cholesterol regulatory pathway with Boolean networks. 2008 BMC Syst Biol pmid:19025648
Tekle M et al. Investigation of coenzyme Q biosynthesis in human fibroblast and HepG2 cells. 2008 J. Biochem. Biophys. Methods pmid:17916383
Cornish J et al. Modulation of osteoclastogenesis by fatty acids. 2008 Endocrinology pmid:18617622
Okada K et al. Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. 2008 Plant Cell Physiol. pmid:18303110
Lüdke SM et al. Stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. 2008 J. Lipid Res. pmid:18669481
Winiarska M et al. Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. 2008 PLoS Med. pmid:18366248
Oliveira KA et al. Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction. 2008 J. Bioenerg. Biomembr. pmid:18679777
Sapir-Mir M et al. Peroxisomal localization of Arabidopsis isopentenyl diphosphate isomerases suggests that part of the plant isoprenoid mevalonic acid pathway is compartmentalized to peroxisomes. 2008 Plant Physiol. pmid:18988695
Sławińska A and Kandefer-Szerszeń M [The anticancer properties of statins]. 2008 Postepy Hig Med Dosw (Online) pmid:18688209
Acharjee S and Welty FK Atorvastatin and cardiovascular risk in the elderly--patient considerations. 2008 Clin Interv Aging pmid:18686752
Journe F et al. Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. 2008 Breast Cancer Res. Treat. pmid:17333335
Sando T et al. Cloning and characterization of mevalonate pathway genes in a natural rubber producing plant, Hevea brasiliensis. 2008 Biosci. Biotechnol. Biochem. pmid:18685207
Laezza C et al. The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway. 2008 Endocr. Relat. Cancer pmid:18676619
Bate C et al. Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells. 2008 BMC Biol. pmid:18789130
Kistowska M et al. Dysregulation of the host mevalonate pathway during early bacterial infection activates human TCR gamma delta cells. 2008 Eur. J. Immunol. pmid:18624305
Matsuda T et al. Simvastatin inhibits catecholamine secretion and synthesis induced by acetylcholine via blocking Na+ and Ca2+ influx in bovine adrenal medullary cells. 2008 J. Pharmacol. Exp. Ther. pmid:18593956
Habara K et al. Pitavastatin up-regulates the induction of iNOS through enhanced stabilization of its mRNA in pro-inflammatory cytokine-stimulated hepatocytes. 2008 Nitric Oxide pmid:17936042
Fried LF Effects of HMG-CoA reductase inhibitors (statins) on progression of kidney disease. 2008 Kidney Int. pmid:18528321
Skorupinska-Tudek K et al. Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. 2008 J. Biol. Chem. pmid:18502754
Zhang X et al. Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. 2008 J. Immunol. pmid:18453621
Aprigliano I et al. Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells. 2008 Liver Int. pmid:18339080
Glynn SA et al. The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. 2008 BMC Cancer pmid:18199328
Galichet A et al. Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. 2008 Plant Physiol. pmid:18184738
Kodaman PH and Duleba AJ Statins in the treatment of polycystic ovary syndrome. 2008 Semin. Reprod. Med. pmid:18181091
Wilson GJ et al. Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review. 2008 Nutr Metab (Lond) pmid:18173841
Mathew B and Biju R Neuroprotective effects of garlic a review. 2008 Libyan J Med pmid:21499478
Yoshida T et al. Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. 2008 Anal Chem Insights pmid:19609389
Saito A et al. Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells. 2008 Melanoma Res. pmid:18337644
Baba TT et al. Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway. 2008 J. Muscle Res. Cell. Motil. pmid:18792797
Habeos IG et al. Simvastatin activates Keap1/Nrf2 signaling in rat liver. 2008 J. Mol. Med. pmid:18787804
Osman L et al. Atorvastatin accelerates extracellular nucleotide degradation in human endothelial cells. 2008 Mol. Cell. Biochem. pmid:18158588
Martin-Ventura JL et al. LDL induces parathyroid hormone-related protein expression in vascular smooth muscle cells: Modulation by simvastatin. 2008 Atherosclerosis pmid:18378243
Baldi A and Dixit VK Yield enhancement strategies for artemisinin production by suspension cultures of Artemisia annua. 2008 Bioresour. Technol. pmid:17804216
Park SY et al. Inhibitory effect of simvastatin on the TNF-alpha- and angiotensin II-induced monocyte adhesion to endothelial cells is mediated through the suppression of geranylgeranyl isoprenoid-dependent ROS generation. 2008 Arch. Pharm. Res. pmid:18365690
Begley M et al. Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection. 2008 Infect. Immun. pmid:18765739
Tarhzaoui K et al. Effect of rosuvastatin on capillary filtration of albumin and blood pressure in rats with streptozotocin-induced diabetes. 2008 Diabetes Res. Clin. Pract. pmid:18406000
Zhuge B et al. Bioconversion of lovastatin to a novel statin by Amycolatopsis sp. 2008 Appl. Microbiol. Biotechnol. pmid:18368405
Kaliszewski P et al. Rsp5p ubiquitin ligase and the transcriptional activators Spt23p and Mga2p are involved in co-regulation of biosynthesis of end products of the mevalonate pathway and triacylglycerol in yeast Saccharomyces cerevisiae. 2008 Biochim. Biophys. Acta pmid:18771750
Voynova NE et al. Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. 2008 Arch. Biochem. Biophys. pmid:18823933
Pscheidt B and Glieder A Yeast cell factories for fine chemical and API production. 2008 Microb. Cell Fact. pmid:18684335
Schwartz YSh et al. Cholesterol-induced stimulation of postinflammatory liver fibrosis. 2008 Bull. Exp. Biol. Med. pmid:19110552
Liang YJ et al. Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products. 2008 Cardiology pmid:18057884
de Ruyck J and Wouters J Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes. 2008 Curr. Protein Pept. Sci. pmid:18393884