Bergstrom JD et al. |
Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase. |
2000 |
Arch. Biochem. Biophys. |
pmid:10620343
|
Szkopińska A et al. |
The regulation of activity of main mevalonic acid pathway enzymes: farnesyl diphosphate synthase, 3-hydroxy-3-methylglutaryl-CoA reductase, and squalene synthase in yeast Saccharomyces cerevisiae. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10623644
|
Aboushadi N et al. |
Characterization of peroxisomal 3-hydroxy-3-methylglutaryl coenzyme A reductase in UT2 cells: sterol biosynthesis, phosphorylation, degradation, and statin inhibition. |
2000 |
Biochemistry |
pmid:10625499
|
Wagner AH et al. |
Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation. |
2000 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:10634801
|
Lindenthal B and von Bergmann K |
Urinary excretion and serum concentration of mevalonic acid during acute intake of alcohol. |
2000 |
Metab. Clin. Exp. |
pmid:10647065
|
Kuzuyama T et al. |
Cloning and characterization of 1-deoxy-D-xylulose 5-phosphate synthase from Streptomyces sp. Strain CL190, which uses both the mevalonate and nonmevalonate pathways for isopentenyl diphosphate biosynthesis. |
2000 |
J. Bacteriol. |
pmid:10648511
|
Haratake A et al. |
Topical mevalonic acid stimulates de novo cholesterol synthesis and epidermal permeability barrier homeostasis in aged mice. |
2000 |
J. Invest. Dermatol. |
pmid:10651982
|
Cvejić JH and Rohmer M |
CO2 as main carbon source for isoprenoid biosynthesis via the mevalonate-independent methylerythritol 4-phosphate route in the marine diatoms Phaeodactylum tricornutum and Nitzschia ovalis. |
2000 |
Phytochemistry |
pmid:10656403
|
|
|
|
|
pmid:10665838
|
Hanley K et al. |
Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription. |
2000 |
J. Invest. Dermatol. |
pmid:10692116
|
Lambert M and Bui ND |
Dexamethasone-induced decrease in HMG-CoA reductase and protein-farnesyl transferase activities does not impair ras processing in AR 4-2J cells. |
1999 |
Mol. Cell. Biochem. |
pmid:10706000
|
|
|
|
|
pmid:10728920
|
Turunen M et al. |
Influence of peroxisome proliferator-activated receptor alpha on ubiquinone biosynthesis. |
2000 |
J. Mol. Biol. |
pmid:10731415
|
Flach J et al. |
The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10733934
|
Hashimoto F et al. |
Changes in isoprenoid lipid synthesis by gemfibrozil and clofibric acid in rat hepatocytes. |
2000 |
Biochem. Pharmacol. |
pmid:10736420
|
Coppens I et al. |
Toxoplasma gondii exploits host low-density lipoprotein receptor-mediated endocytosis for cholesterol acquisition. |
2000 |
J. Cell Biol. |
pmid:10747095
|
Tanaka T et al. |
Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition. |
2000 |
J. Neurosci. |
pmid:10751437
|
|
|
|
|
pmid:10774794
|
Woo JT et al. |
Compactin suppresses bone resorption by inhibiting the fusion of prefusion osteoclasts and disrupting the actin ring in osteoclasts. |
2000 |
J. Bone Miner. Res. |
pmid:10780857
|
Leonardsen L et al. |
Effect of inhibition of sterol delta 14-reductase on accumulation of meiosis-activating sterol and meiotic resumption in cumulus-enclosed mouse oocytes in vitro. |
2000 |
J. Reprod. Fertil. |
pmid:10793639
|
Tasevski V et al. |
Mitogenic effect of lithium in FRTL-5 cells can be reversed by blocking de novo cholesterol synthesis and subsequent signal transduction. |
2000 |
Thyroid |
pmid:10807058
|
|
|
|
|
pmid:10814523
|
RodrÃguez-Concepción M et al. |
Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. |
2000 |
FEBS Lett. |
pmid:10818234
|
Vishnuvardhan D and Beinfeld MC |
Lovastatin is a potent inhibitor of cholecystokinin secretion in endocrine tumor cells in culture. |
2000 |
Peptides |
pmid:10822111
|
Ashar HR et al. |
Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules. |
2000 |
J. Biol. Chem. |
pmid:10852915
|
|
|
|
|
pmid:10856525
|
Raal FJ et al. |
Inhibition of cholesterol synthesis by atorvastatin in homozygous familial hypercholesterolaemia. |
2000 |
Atherosclerosis |
pmid:10856535
|
Schulte AE et al. |
Purification and characterization of mevalonate kinase from suspension-cultured cells of Catharanthus roseus (L.) G. Don. |
2000 |
Arch. Biochem. Biophys. |
pmid:10860546
|
Montalvetti A et al. |
Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase. |
2000 |
Biochem. J. |
pmid:10861207
|
|
|
|
|
pmid:10872206
|
Stickney JT and Buss JE |
Murine guanylate-binding protein: incomplete geranylgeranyl isoprenoid modification of an interferon-gamma-inducible guanosine triphosphate-binding protein. |
2000 |
Mol. Biol. Cell |
pmid:10888661
|
Takagi M et al. |
A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190. |
2000 |
J. Bacteriol. |
pmid:10894721
|
Wilding EI et al. |
Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci. |
2000 |
J. Bacteriol. |
pmid:10894743
|
|
|
|
|
pmid:10896295
|
|
|
|
|
pmid:10896296
|
|
|
|
|
pmid:10899
|
|
|
|
|
pmid:10908155
|
|
|
|
|
pmid:10917872
|
Hirai N et al. |
Biosynthesis of abscisic acid by the non-mevalonate pathway in plants, and by the mevalonate pathway in fungi. |
2000 |
Biosci. Biotechnol. Biochem. |
pmid:10945263
|
Nilsson A |
Increased cholesterol-ester formation during forced cholesterol synthesis in rat hepatocytes. |
1975 |
Eur. J. Biochem. |
pmid:1097241
|
Itoh D et al. |
Nonequivalent labeling of the phytyl side chain of chlorophyll a in callus of the hornwort Anthoceros punctatus. |
2000 |
J. Nat. Prod. |
pmid:10978203
|
Ikeda U et al. |
Fluvastatin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cells. |
2000 |
Hypertension |
pmid:10988259
|
Shimizu I and Katsuki H |
Effect of temperature on ergosterol biosynthesis in yeast. |
1975 |
J. Biochem. |
pmid:1099086
|
Moreau JP et al. |
Biosynthesis of sterols by a yeast homogenate. Incorporation of mevalonic acid into cholesta-5,7,24-trien-3beta-ol and 5alpha-cholesta-7,24-dien-3beta-ol. |
1975 |
Eur. J. Biochem. |
pmid:1100393
|
Hernández-Perera O et al. |
Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells. |
2000 |
Circ. Res. |
pmid:11009568
|
Hausding M et al. |
Inhibition of small G proteins of the rho family by statins or clostridium difficile toxin B enhances cytokine-mediated induction of NO synthase II. |
2000 |
Br. J. Pharmacol. |
pmid:11015307
|
|
|
|
|
pmid:11035257
|
Smit A and Mushegian A |
Biosynthesis of isoprenoids via mevalonate in Archaea: the lost pathway. |
2000 |
Genome Res. |
pmid:11042147
|
|
|
|
|
pmid:11053993
|
|
|
|
|
pmid:11058703
|