| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee MH et al. | Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation. | 2007 | Stem Cells | pmid:17464088 |
| Haratake A et al. | Acceleration of de novo cholesterol synthesis in the epidermis influences desquamation of the stratum corneum in aged mice. | 2006 | Skin Pharmacol Physiol | pmid:16778459 |
| Kodaman PH and Duleba AJ | Statins in the treatment of polycystic ovary syndrome. | 2008 | Semin. Reprod. Med. | pmid:18181091 |
| Bellosta S et al. | Statins effect on smooth muscle cell proliferation. | 2004 | Semin Vasc Med | pmid:15861311 |
| Cornforth JW | Asymmetry and enzyme action. | 1976 | Science | pmid:935862 |
| Edmond J et al. | Mevalonate metabolism: role of kidneys. | 1976 | Science | pmid:935865 |
| Farnsworth CC et al. | Identification of geranylgeranyl-modified proteins in HeLa cells. | 1990 | Science | pmid:2296721 |
| MEROLA AJ and ARNOLD A | ESTRONE INHIBITION OF CHOLESTEROL BIOSYNTHESIS AT THE MEVALONIC ACID STAGE. | 1964 | Science | pmid:14169718 |
| FIMOGNARI GM and RODWELL VW | CHOLESTEROL BIOSYNTHESIS: MEVALONATE SYNTHESIS INHIBITED BY BILE SALTS. | 1965 | Science | pmid:14245778 |
| Graebe JE | Isoprenoid biosynthesis in a cell-free system from pea shoots. | 1967 | Science | pmid:4381746 |
| Yi P et al. | The mevalonate pathway controls heart formation in Drosophila by isoprenylation of Ggamma1. | 2006 | Science | pmid:16857902 |
| Galli G et al. | Sterol precursors of cholesterol in adult human brain. | 1968 | Science | pmid:5700071 |
| Jomaa H et al. | Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. | 1999 | Science | pmid:10477522 |
| Matsumoto Y et al. | A critical role of mevalonate for peptidoglycan synthesis in Staphylococcus aureus. | 2016 | Sci Rep | pmid:26961421 |
| Pina ES et al. | Mevalonate-derived quinonemethide triterpenoid from in vitro roots of Peritassa laevigata and their localization in root tissue by MALDI imaging. | 2016 | Sci Rep | pmid:26943243 |
| Kain V et al. | Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism. | 2015 | Sci Rep | pmid:26345110 |
| Warita K et al. | Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. | 2014 | Sci Rep | pmid:25534349 |
| Omar SH | Oleuropein in olive and its pharmacological effects. | 2010 Apr-Jun | Sci Pharm | pmid:21179340 |
| Feitosa AO et al. | Lethality of cytochalasin B and other compounds isolated from fungus Aspergillus sp. (Trichocomaceae) endophyte of Bauhinia guianensis (Fabaceae). | 2016 Jul - Sep | Rev. Argent. Microbiol. | pmid:27567521 |
| Ali OF et al. | Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. | 2011 | Respir. Res. | pmid:21999923 |
| Schaafsma D et al. | Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. | 2011 | Respir. Res. | pmid:21864337 |
| Capra V and Rovati GE | Rosuvastatin inhibits human airway smooth muscle cells mitogenic response to eicosanoid contractile agents. | 2014 | Pulm Pharmacol Ther | pmid:23806820 |
| Olson AL et al. | Substrate induced structural and dynamics changes in human phosphomevalonate kinase and implications for mechanism. | 2009 | Proteins | pmid:18798562 |
| Vinokur JM et al. | Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. | 2015 | Protein Sci. | pmid:25422158 |
| Korman TP et al. | A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates. | 2014 | Protein Sci. | pmid:24623472 |
| Rosenthal RS and Rodwell VW | Purification and characterization of the heteromeric transcriptional activator MvaT of the Pseudomonas mevalonii mvaAB operon. | 1998 | Protein Sci. | pmid:9514272 |
| Andreassi JL et al. | Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate. | 2007 | Protein Sci. | pmid:17400916 |
| Hedl M and Rodwell VW | Inhibition of the class II HMG-CoA reductase of Pseudomonas mevalonii. | 2004 | Protein Sci. | pmid:15152097 |
| Hedl M and Rodwell VW | Enterococcus faecalis mevalonate kinase. | 2004 | Protein Sci. | pmid:14767074 |
| Kim DY et al. | Expression and characterization of the HMG-CoA reductase of the thermophilic archaeon Sulfolobus solfataricus. | 1999 | Protein Expr. Purif. | pmid:10600463 |
| Yildirim FI et al. | Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS. | 2015 | Prostaglandins Other Lipid Mediat. | pmid:26201058 |
| Kabara JJ | A critical review of brain cholesterol metabolism. | 1973 | Prog. Brain Res. | pmid:4608424 |
| Popják G and Meenan A | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase: search for the enzyme's repressor derived from mevalonate. | 1987 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:2892200 |
| Cornforth J | Symmetry of squalene epoxidation in vivo. | 1977 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:22855 |
| Forman BM et al. | The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9380679 |
| Arebalo RE et al. | In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: immunotitration of the enzyme after short-term mevalonate or cholesterol feeding. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6948302 |
| Epstein WW et al. | Quantitation of prenylcysteines by a selective cleavage reaction. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1946384 |
| Parker TS et al. | Mevalonic acid in human plasma: relationship of concentration and circadian rhythm to cholesterol synthesis rates in man. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6953446 |
| Lange BM and Croteau R | Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570138 |
| Rauthan M et al. | The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23530189 |
| Yasmin S et al. | Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22106303 |
| Larson RA et al. | Neutrophils are required for the DNA synthetic response of human lymphocytes to mevalonic acid: evidence suggesting that a nonsterol product of mevalonate is involved. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6953445 |
| Kinsella BT et al. | Posttranslational modification of Ha-ras p21 by farnesyl versus geranylgeranyl isoprenoids is determined by the COOH-terminal amino acid. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1924354 |
| Casey PJ et al. | p21ras is modified by a farnesyl isoprenoid. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2682646 |
| Kawata M et al. | Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2123345 |
| Wang Z et al. | Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24367099 |
| Hecht S et al. | Studies on the nonmevalonate pathway to terpenes: the role of the GcpE (IspG) protein. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11752431 |
| Kaneda K et al. | An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11158573 |
| Takahashi S et al. | A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9707569 |
| James G et al. | Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8633088 |