Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Martín D et al. Inhibition of vitellogenin production by allatostatin in the German cockroach. 1996 Mol. Cell. Endocrinol. pmid:8892320
Honda A et al. Effect of YM 9429, a potent teratogen, on cholesterol biosynthesis in cultured cells and rat liver microsomes. 1996 Steroids pmid:8883221
Kurakata S et al. Effects of different inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, pravastatin sodium and simvastatin, on sterol synthesis and immunological functions in human lymphocytes in vitro. 1996 Immunopharmacology pmid:8880225
Parmryd I and Dallner G Organization of isoprenoid biosynthesis. 1996 Biochem. Soc. Trans. pmid:8878825
Jones PJ et al. Dietary cholesterol feeding suppresses human cholesterol synthesis measured by deuterium incorporation and urinary mevalonic acid levels. 1996 Arterioscler. Thromb. Vasc. Biol. pmid:8857917
pmid:8835365
Reimann FM et al. Reduced cholesterol esterification in CaCo-2 cells by indirect action of pravastatin. 1996 Atherosclerosis pmid:8831928
Satoh T et al. The effects of pravastatin, an HMG-CoA reductase inhibitor, on cell viability and DNA production of rat hepatocytes. 1996 Life Sci. pmid:8831797
Nantais DE et al. Prenylation of an interferon-gamma-induced GTP-binding protein: the human guanylate binding protein, huGBP1. 1996 J. Leukoc. Biol. pmid:8830800
Knöss W and Reuter B Biosynthesis of [14C]geranylgeranyldiphosphate by a prenyl transferase system from a mutant strain of Gibberella fujikuroi. 1996 Anal. Biochem. pmid:8811910
McGee TP et al. Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis. 1996 J. Biol. Chem. pmid:8810339
Naoumova RP et al. Plasma mevalonic acid, an index of cholesterol synthesis in vivo, and responsiveness to HMG-CoA reductase inhibitors in familial hypercholesterolaemia. 1996 Atherosclerosis pmid:8808497
pmid:8807496
Taylor GW et al. Excursions in biomedical mass spectrometry. 1996 Br J Clin Pharmacol pmid:8807152
pmid:8793275
Andersson M et al. Age-dependent modifications in the metabolism of mevalonate pathway lipids in rat brain. 1995 Mech. Ageing Dev. pmid:8789251
Miquel K et al. Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells. 1996 Biochem. Biophys. Res. Commun. pmid:8780704
Domenech CE et al. Separate compartments for the production of sterols, carotenoids and gibberellins in Gibberella fujikuroi. 1996 Eur. J. Biochem. pmid:8774718
Nishio E et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor impairs cell p4fferentiation in cultured adipogenic cells (3T3-L1). 1996 Eur. J. Pharmacol. pmid:8773465
Feillet C et al. Comparative effects of simvastatin and pravastatin on cholesterol synthesis in patients with primary hypercholesterolemia. 1995 Atherosclerosis pmid:8770319
Guyton JR et al. Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants. 1995 Atherosclerosis pmid:8770318
Ku EC Regulation of fatty acid biosynthesis by intermediates of the cholesterol biosynthetic pathway. 1996 Biochem. Biophys. Res. Commun. pmid:8769113
Dimster-Denk D and Rine J Transcriptional regulation of a sterol-biosynthetic enzyme by sterol levels in Saccharomyces cerevisiae. 1996 Mol. Cell. Biol. pmid:8754796
Velázquez OC et al. Butyrate inhibits seeding and growth of colorectal metastases to the liver in mice. 1996 Surgery pmid:8751616
pmid:8750242
pmid:8747489
Sliwowski JK et al. The in vivo biosynthesis of cholesterol from (3RS,2R) [2-14C,2-3H]mevalonic acid in the brains of rats on normal and protein deficient diets. The stereochemistry of tritium atoms at C-7 and C-15. 1977 J. Neurochem. pmid:874493
Lakshmanan MR and Veech RL Measurement of rate of rat liver sterol synthesis in vivo using tritiated water. 1977 J. Biol. Chem. pmid:873910
Hebbachi AM and Gibbons GF Retention of orotic acid effect on very low density lipoproteins secretion in cultured hepatocytes. 1996 Biochem. Soc. Trans. pmid:8736835
Goto S et al. Species specificity in the blood cholesterol-lowering effect of YM-16638. 1996 Br. J. Pharmacol. pmid:8733592
Naoumova RP et al. Acute hyperinsulinaemia decreases cholesterol synthesis less in subjects with non-insulin-dependent diabetes mellitus than in non-diabetic subjects. 1996 Eur. J. Clin. Invest. pmid:8732493
Thompson GR et al. Role of cholesterol in regulating apolipoprotein B secretion by the liver. 1996 J. Lipid Res. pmid:8728309
Scoppola A et al. Effects of insulin on cholesterol synthesis in type II diabetes patients. 1995 Diabetes Care pmid:8721938
Brown GR et al. Synthesis and activity of a novel series of 3-biarylquinuclidine squalene synthase inhibitors. 1996 J. Med. Chem. pmid:8709131
pmid:8702422
Fogelman AM et al. Cholesterol biosynthesis in human lymphocytes, monocytes, and granulocytes. 1977 Biochem. Biophys. Res. Commun. pmid:869944
pmid:8692019
Konrad M and Merz WE Long-term effect of cyclic AMP on N-glycosylation is caused by an increase in the activity of the cis-prenyltransferase. 1996 Biochem. J. pmid:8687403
Carlberg M et al. Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth. 1996 J. Biol. Chem. pmid:8663239
Rostas JA et al. Selective labelling of two phases of axonal transport of cholesterol in the chick optic system. 1979 J. Neurochem. pmid:86598
Grönroos E et al. Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho. 1996 Biochem. J. pmid:8645211
Keller RK et al. Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. 1996 Arch. Biochem. Biophys. pmid:8645011
Carlberg M and Larsson O Stimulatory effect of PDGF on HMG-CoA reductase activity and N-linked glycosylation contributes to increased expression of IGF-1 receptors in human fibroblasts. 1996 Exp. Cell Res. pmid:8635486
James G et al. Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8633088
McTaggart F et al. Inhibition of squalene synthase of rat liver by novel 3' substituted quinuclidines. 1996 Biochem. Pharmacol. pmid:8630089
Alaei P et al. Inhibition of protein prenylation down-regulates signalling by inflammatory mediators in human keratinocytes. 1996 Biochem. Biophys. Res. Commun. pmid:8630058
Meigs TE et al. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo. 1996 J. Biol. Chem. pmid:8626470
pmid:8617335
Faas FH et al. Unsaturated fatty acyl-CoA inhibition of cholesterol synthesis in vitro. 1977 Biochim. Biophys. Acta pmid:861236
Veerkamp JH et al. Effects of HMG-CoA reductase inhibitors on growth and differentiation of cultured rat skeletal muscle cells. 1996 Biochim. Biophys. Acta pmid:8611662