Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Authors Title Published Journal PubMed Link
Chen Y et al. Mevalonate inhibits acid sphingomyelinase activity, increases sphingomyelin levels and inhibits cell proliferation of HepG2 and Caco-2 cells. 2015 Lipids Health Dis pmid:26493087
Laezza C et al. p53 regulates the mevalonate pathway in human glioblastoma multiforme. 2015 Cell Death Dis pmid:26469958
Rondini EA et al. Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat Hepatocytes. 2015 J. Pharmacol. Exp. Ther. pmid:26427720
Guan Z et al. Metabolic engineering of Bacillus subtilis for terpenoid production. 2015 Appl. Microbiol. Biotechnol. pmid:26373726
Pandyra AA et al. Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death. 2015 Oncotarget pmid:26353928
Kuo KK et al. Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss. 2015 J. Lipid Res. pmid:26351364
Kain V et al. Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism. 2015 Sci Rep pmid:26345110
Henry LK et al. Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:26216978
Matsuo S et al. Single-dose rosuvastatin ameliorates lung ischemia-reperfusion injury via upregulation of endothelial nitric oxide synthase and inhibition of macrophage infiltration in rats with pulmonary hypertension. 2015 J. Thorac. Cardiovasc. Surg. pmid:25454916
Vinokur JM et al. Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. 2015 Protein Sci. pmid:25422158
Greife A et al. Establishment and characterization of a bladder cancer cell line with enhanced doxorubicin resistance by mevalonate pathway activation. 2015 Tumour Biol. pmid:25566959
Burgazli KM et al. The impact of statins on FGF-2-stimulated human umbilical vein endothelial cells. 2014 Postgrad Med pmid:24393759
Moise AR et al. Mechanistic aspects of carotenoid biosynthesis. 2014 Chem. Rev. pmid:24175570
Jiang P et al. In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells. 2014 Br. J. Cancer pmid:25093497
Sivanandhan G et al. Enhanced biosynthesis of withanolides by elicitation and precursor feeding in cell suspension culture of Withania somnifera (L.) Dunal in shake-flask culture and bioreactor. 2014 PLoS ONE pmid:25089711
Rastogi S et al. De novo sequencing and comparative analysis of holy and sweet basil transcriptomes. 2014 BMC Genomics pmid:25015319
Fabris M et al. Tracking the sterol biosynthesis pathway of the diatom Phaeodactylum tricornutum. 2014 New Phytol. pmid:24996048
Pandyra A et al. Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop. 2014 Cancer Res. pmid:24994712
Li J et al. De novo synthesis of steroids and oxysterols in adipocytes. 2014 J. Biol. Chem. pmid:24280213
González-Caballero N et al. Expression of the mevalonate pathway enzymes in the Lutzomyia longipalpis (Diptera: Psychodidae) sex pheromone gland demonstrated by an integrated proteomic approach. 2014 J Proteomics pmid:24185139