Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

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All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
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Domoki F et al. Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons. 2009 Am. J. Physiol., Cell Physiol. pmid:18971391
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Riganti C et al. Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition. 2007 Am. J. Respir. Cell Mol. Biol. pmid:17322126
Zeki AA et al. Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond. 2009 Am. J. Respir. Crit. Care Med. pmid:19608720
Rubins JB et al. Lovastatin induces apoptosis in malignant mesothelioma cells. 1998 Am. J. Respir. Crit. Care Med. pmid:9603146
Nürenberg G and Volmer DA The analytical determination of isoprenoid intermediates from the mevalonate pathway. 2012 Anal Bioanal Chem pmid:21789486
Yoshida T et al. Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. 2008 Anal Chem Insights pmid:19609389
Wang CZ and Miziorko HM Methodology for synthesis and isolation of 5-phosphomevalonic acid. 2003 Anal. Biochem. pmid:14511696
Gerber R et al. Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS. 2004 Anal. Biochem. pmid:15136164
Ong KK et al. Assay of 3-hydroxy-3-methylglutaryl CoA reductase activity using anionic-exchange column chromatography. 1991 Anal. Biochem. pmid:1776669
Krieger M The use of amphotericin B to detect inhibitors of cellular cholesterol biosynthesis. 1983 Anal. Biochem. pmid:6559041
McCaskill D and Croteau R Procedures for the isolation and quantification of the intermediates of the mevalonic acid pathway. 1993 Anal. Biochem. pmid:8297005
Knöss W and Reuter B Biosynthesis of [14C]geranylgeranyldiphosphate by a prenyl transferase system from a mutant strain of Gibberella fujikuroi. 1996 Anal. Biochem. pmid:8811910
Raschke M et al. A high-performance liquid chromatography method for the analysis of intermediates of the deoxyxylulose phosphate pathway. 2004 Anal. Biochem. pmid:15556562
Birnberg PR et al. An improved enzymatic synthesis of labeled gibberellin A12-aldehyde and gibberellin A12. 1986 Anal. Biochem. pmid:3754395
Loker E et al. Phenobarbital-induced proliferation of smooth endoplasmic reticulum after administration of triparanol. 1970 Anat. Rec. pmid:5506924
Waldron J and Webster C Liquid chromatography-tandem mass spectrometry method for the measurement of serum mevalonic acid: a novel marker of hydroxymethylglutaryl coenzyme A reductase inhibition by statins. 2011 Ann. Clin. Biochem. pmid:21355014
Dempsey ME Inhibition of lipid biosynthesis. 1968 Ann. N. Y. Acad. Sci. pmid:4385358
Krisans SK Cell compartmentalization of cholesterol biosynthesis. 1996 Ann. N. Y. Acad. Sci. pmid:8993542
Aguilera JA et al. Postnatal development of the sterol and nonsterol mevalonate metabolism in chick liver and kidneys. Effect of cholesterol feeding. 1984 Ann. Nutr. Metab. pmid:6517527
Lala A et al. The effects of insulin on plasma mevalonate concentrations in man. 1994 Ann. Nutr. Metab. pmid:7710260
Sablé-Amplis R et al. Hepatic cholesterogenesis and cholesterol 7 alpha-hydroxylase activity in hamsters fed diets enriched with pectins and/or cholesterol. 1987 Ann. Nutr. Metab. pmid:3827206
Barter MJ et al. Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation. 2010 Ann. Rheum. Dis. pmid:20693272
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Rudney H and Sexton RC Regulation of cholesterol biosynthesis. 1986 Annu. Rev. Nutr. pmid:3524618
Garcia-Ruiz C et al. Statins and protein prenylation in cancer cell biology and therapy. 2012 Anticancer Agents Med Chem pmid:22413970
Li YY et al. Zoledronic acid induces cell-cycle prolongation in murine lung cancer cells by perturbing cyclin and Ras expression. 2011 Anticancer Drugs pmid:20926944
Björkhem-Bergman L et al. Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation. 2010 Anticancer Res. pmid:20530415
Matsunaga S et al. Incadronate induces cell detachment and apoptosis in prostatic PC-3 cells. 2007 Mar-Apr Anticancer Res. pmid:17465222
Caruso MG and Notarnicola M Biochemical changes of mevalonate pathway in human colorectal cancer. 2005 Sep-Oct Anticancer Res. pmid:16101154
Martín-Navarro CM et al. Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and application of statins as a novel effective therapeutic approach against Acanthamoeba infections. 2013 Antimicrob. Agents Chemother. pmid:23114753
Yu W et al. The mevalonate auxotrophic mutant of Staphylococcus aureus can adapt to mevalonate depletion. 2013 Antimicrob. Agents Chemother. pmid:23959312
Ryder NS Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent. 1985 Antimicrob. Agents Chemother. pmid:4039119
Ryder NS et al. Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans. 1984 Antimicrob. Agents Chemother. pmid:6375557