Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

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All references with Mevalonic acid

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Authors Title Published Journal PubMed Link
pmid:1308625
Bokoch GM and Prossnitz V Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells. 1992 J. Clin. Invest. pmid:1310693
Khosravi-Far R et al. Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct. 1992 J. Biol. Chem. pmid:1332953
HONG L and WRIGHT LD Paper chromatography of mevalonate and acetate. 1957 Biochim. Biophys. Acta pmid:13479486
Buchwald H Cholesterol inhibition, cancer, and chemotherapy. 1992 Lancet pmid:1349377
pmid:1353519
Sunazuka T et al. Synthesis of 1233A analogs and their inhibitory activity against hydroxymethylglutaryl coenzyme A synthase. 1992 J. Antibiot. pmid:1355474
PARK RB and BONNER J Enzymatic synthesis of rubber from mevalonic acid. 1958 J. Biol. Chem. pmid:13563498
GOODWIN TW Studies in carotenogenesis. 25. The incorporation of 14CO2, [2-14C] acetate and [2-14C]mevalonate into beta-carotene by illuminated etiolated maize seedings. 1958 Biochem. J. pmid:13607416
MARKLEY K and GURIN S Decarboxylation of mevalonic acid and conversion to squalene; enzyme fractionation and cofactors. 1959 Biochim. Biophys. Acta pmid:13628647
GOSSELIN L and POPJAK G Studies on biosynthesis of cholesterol. 8. The effect of Mg2+ and Mn2+ ions and of adenosine triphosphate on enzymic activity of microsomes in sterol biosynthesis from mevalonic acid. 1959 Biochem. J. pmid:13651113
PURCELL AE et al. The incorporation of mevalonic acid into tomato carotenoids. 1959 J. Biol. Chem. pmid:13654323
RILLING HC and BLOCH K On the mechanism of squaiene biogenesis from mevalonic acid. 1959 J. Biol. Chem. pmid:13654391
pmid:13727607
POPJAK G et al. Studies on the biosynthesis of cholesterol. XV. Mechanism of squalene biosynthesis from farnesyl pyrophosphate and from mevalonate. 1961 J. Biol. Chem. pmid:13737104
pmid:13739420
SCHLESINGER MJ and COON MJ Reduction of mevaldic acid to mevalonic acid by a partially purified enzyme from liver. 1961 J. Biol. Chem. pmid:13747804
SHAH SN et al. The effect of growth hormone administration and dietary protein on the incorporation of sodium acetate-2-C14 and mevalonic acid-2-C14 into liver cholesterol. 1961 Arch. Biochem. Biophys. pmid:13750592
TADA M and LYNEN F [On the biosynthesis of terpenes. XIV. On the determination of phosphomevalonic acid kinase and pyrophosphomevalonic acid decarboxylase in cell extracts]. 1961 J. Biochem. pmid:13774769
Schafer BL et al. Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria. 1992 J. Biol. Chem. pmid:1377680
pmid:13793365
BLOCH K et al. Mevalonic acid pyrophosphate and isopentenylpyrophosphate. 1959 J. Biol. Chem. pmid:13801508
DE WAARD A and POPJAK G Studies on the biosynthesis of cholesterol. 9. Formation of phosphorylated derivatives of mevalonic acid in liver-enzyme preparations. 1959 Biochem. J. pmid:13815126
DURR IF and RUDNEY H The reduction of beta-hydroxy-beta-methyl-glutaryl coenzyme A to mevalonic acid. 1960 J. Biol. Chem. pmid:13818862
ELWOOD JC et al. Lipid metabolism in the diabetic rat. IV. Metabolism of acetate, acetoacetate, butyrate, and mevalonate in vitro. 1960 J. Biol. Chem. pmid:13820133
GARATTINI S et al. Lipid biosynthesis in vivo from acetate-1-C 14 and 2-C 14 and mevalonic-2-C 14 acid. 1959 Arch. Biochem. Biophys. pmid:13826357
WITTING LA and PORTER JW Intermediates in the conversion of mevalonic acid to squalene by a rat liver enzyme system. 1959 J. Biol. Chem. pmid:13845505
BRAITHWAITE GD and GOODWIN TW Studies in carotenogenesis. 26. The incorporation of [C14] acetate, [C14] mevalonate and C14-labelled carbon dioxide into beta-carotene by the fungus Phycomyces blakesleeanus. 1960 Biochem. J. pmid:13849152
BRAITHWAITE GD and GOODWIN TW Studies in carotenogenesis. 27. Incorporation of [2-14C] acetate, DL-[2-14C] mevalonate and C14-labelled carbon dioxide into carrotroot preparations. 1960 Biochem. J. pmid:13849153
NICHOLAS HJ and THOMAS BE Intracerebral incorporation of [2-14C]mevalonic acid into adult rat brain squalene and cholesterol. 1959 Biochim. Biophys. Acta pmid:13854106
pmid:13874154
Manzi P et al. Seasonal commitment of HMGCoA reductase activity to vitellogenin production. 1992 Biosci. Rep. pmid:1391685
pmid:13921034
pmid:13921035
pmid:13921036
OHNOKI D et al. D5-Phosphomevalonic acid as the intermediate of the enzymatic synthesis of bacterial phytoene. 1962 J. Biochem. pmid:13939688
GAYLOR JL Biosynthesis of skin sterols. V. Effect of arsenite inhibition and the accumulation of labeled lanosta-7, 24-dien-3 beta-ol in rat skin. 1963 Arch. Biochem. Biophys. pmid:13946925
GOODMAN DS et al. Studies of cholesterol biosynthesis. V. The time course and pathway of the later stages of cholesterol biosynthesis in the livers of intact rats. 1963 J. Biol. Chem. pmid:13949089
FUMAGALLI R et al. Cholesterol synthesis in rat brain: differential incorporation of mevalonolactone-2-C14 and potassium mevalonate-2-C14. 1962 Arch. Biochem. Biophys. pmid:13960261
BEELER DA et al. The biosynthesis of squalene from mevalonic acid-2-C-14 and farnesyl pyrophosphate-4,8,12-C-14 by carrot and tomato enzymes. 1963 Arch. Biochem. Biophys. pmid:13970235
pmid:13970858
Adamson P et al. Post-translational modifications of p21rho proteins. 1992 J. Biol. Chem. pmid:1400319
pmid:14011505
BRODIE JD et al. The participation of malonyl coenzyme A in the biosynthesis of mevalonic acid. 1963 J. Biol. Chem. pmid:14015675
RAMASARMA T and RAMAKRISHNAN T Incorporation of [2-14C]mevalonic acid and [2-14C]acetic acid into lipids of mycobacteria. 1961 Biochem. J. pmid:14038591
pmid:14039712
pmid:14065977
PORTMAN OW and SUGANO M THE HYDROLYSIS AND FATTY ACID EXCHANGE OF CHOLESTEROL ESTERS ADMINISTERED IN LIPOPROTEINS TO CEBUS MONKEYS. 1963 Arch. Biochem. Biophys. pmid:14072510
DALY MM et al. CHOLESTEROL CONCENTRATION AND CHOLESTEROL SYNTHESIS IN AORTAS OF RATS WITH RENAL HYPERTENSION. 1963 J. Clin. Invest. pmid:14074354
TERNER C and KORSH G THE BIOSYNTHESIS OF GLYCERIDES IN HOMOGENATES OF NORMAL LACTATING MAMMARY GLAND AND OF MAMMARY TUMOR TISSUE OF THE MOUSE. 1963 Cancer Res. pmid:14079150