Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Celiac Disease D002446 16 associated lipids
Biliary Fistula D001658 13 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Peutz-Jeghers Syndrome D010580 2 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Authors Title Published Journal PubMed Link
Capra V and Rovati GE Rosuvastatin inhibits human airway smooth muscle cells mitogenic response to eicosanoid contractile agents. 2014 Pulm Pharmacol Ther pmid:23806820
Bentinger M et al. Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis. 2014 Biochim. Biophys. Acta pmid:24747199
Yuan J and Ching CB Combinatorial engineering of mevalonate pathway for improved amorpha-4,11-diene production in budding yeast. 2014 Biotechnol. Bioeng. pmid:24122315
Sorrentino G et al. Metabolic control of YAP and TAZ by the mevalonate pathway. 2014 Nat. Cell Biol. pmid:24658687
Al-Haidari AA et al. HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation. 2014 Biochem. Biophys. Res. Commun. pmid:24582560
Schwarz BH et al. Kinetic characterization of an oxidative, cooperative HMG-CoA reductase from Burkholderia cenocepacia. 2014 Biochim. Biophys. Acta pmid:24316250
Smith R et al. Simvastatin inhibits glucose metabolism and legumain activity in human myotubes. 2014 PLoS ONE pmid:24416446
Liu YP et al. Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators. 2014 J. Clin. Invest. pmid:24691443
Burgazli KM et al. The impact of statins on FGF-2-stimulated human umbilical vein endothelial cells. 2014 Postgrad Med pmid:24393759
Hamid PH et al. Differential inhibition of host cell cholesterol de novo biosynthesis and processing abrogates Eimeria bovis intracellular development. 2014 Parasitol. Res. pmid:25199551
Moise AR et al. Mechanistic aspects of carotenoid biosynthesis. 2014 Chem. Rev. pmid:24175570
Khandelwal VK et al. Oxidative stress plays an important role in zoledronic acid-induced autophagy. 2014 Physiol Res pmid:25669691
Warita K et al. Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. 2014 Sci Rep pmid:25534349
Yang J and Guo L Biosynthesis of β-carotene in engineered E. coli using the MEP and MVA pathways. 2014 Microb. Cell Fact. pmid:25403509
Larson-Casey JL et al. Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis. 2014 J. Biol. Chem. pmid:25378391
Shimabukuro-Vornhagen A et al. Inhibition of protein geranylgeranylation specifically interferes with CD40-dependent B cell activation, resulting in a reduced capacity to induce T cell immunity. 2014 J. Immunol. pmid:25311809
Rastogi S et al. De novo sequencing and comparative analysis of holy and sweet basil transcriptomes. 2014 BMC Genomics pmid:25015319
Fabris M et al. Tracking the sterol biosynthesis pathway of the diatom Phaeodactylum tricornutum. 2014 New Phytol. pmid:24996048
Pandyra A et al. Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop. 2014 Cancer Res. pmid:24994712
Kanugula AK et al. Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: intermediacy of nitric oxide and antioxidant defence mechanisms. 2014 FEBS J. pmid:24964743
Workalemahu G et al. Metabolic engineering of Salmonella vaccine bacteria to boost human Vγ2Vδ2 T cell immunity. 2014 J. Immunol. pmid:24943221
Ranji P et al. Loss of HMG-CoA reductase in C. elegans causes defects in protein prenylation and muscle mitochondria. 2014 PLoS ONE pmid:24918786
Vinokur JM et al. Evidence of a novel mevalonate pathway in archaea. 2014 Biochemistry pmid:24914732
Wang Y et al. 24S,25-Epoxycholesterol in mouse and rat brain. 2014 Biochem. Biophys. Res. Commun. pmid:24832732
Xiong M et al. Scalable production of mechanically tunable block polymers from sugar. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:24912182
Rivera-Perez C et al. Metabolic analysis reveals changes in the mevalonate and juvenile hormone synthesis pathways linked to the mosquito reproductive physiology. 2014 Insect Biochem. Mol. Biol. pmid:24833260
Song AA et al. Engineering the lactococcal mevalonate pathway for increased sesquiterpene production. 2014 FEMS Microbiol. Lett. pmid:24828482
Tricarico PM et al. Block of the mevalonate pathway triggers oxidative and inflammatory molecular mechanisms modulated by exogenous isoprenoid compounds. 2014 Int J Mol Sci pmid:24758928
Azami Y et al. (R)-mevalonate 3-phosphate is an intermediate of the mevalonate pathway in Thermoplasma acidophilum. 2014 J. Biol. Chem. pmid:24755225
Zheng X et al. Triterpenoid saponin biosynthetic pathway profiling and candidate gene mining of the Ilex asprella root using RNA-Seq. 2014 Int J Mol Sci pmid:24722569
Liu Y et al. Caenorhabditis elegans pathways that surveil and defend mitochondria. 2014 Nature pmid:24695221
Piłsyk S et al. Overexpression of erg20 gene encoding farnesyl pyrophosphate synthase has contrasting effects on activity of enzymes of the dolichyl and sterol branches of mevalonate pathway in Trichoderma reesei. 2014 Gene pmid:24793581
Ghavami S et al. Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins. 2014 Biochim. Biophys. Acta pmid:24637330
Korman TP et al. A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates. 2014 Protein Sci. pmid:24623472
Yeganeh B et al. Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease. 2014 Pharmacol. Ther. pmid:24582968
Rojo-Arreola L et al. Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis. 2014 PLoS ONE pmid:24489942
Vannice JC et al. Identification in Haloferax volcanii of phosphomevalonate decarboxylase and isopentenyl phosphate kinase as catalysts of the terminal enzyme reactions in an archaeal alternate mevalonate pathway. 2014 J. Bacteriol. pmid:24375100
Wang Z et al. Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:24367099
González-Caballero N et al. Expression of the mevalonate pathway enzymes in the Lutzomyia longipalpis (Diptera: Psychodidae) sex pheromone gland demonstrated by an integrated proteomic approach. 2014 J Proteomics pmid:24185139
Pampalakis G et al. The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway. 2014 Oncotarget pmid:24158494
Bentley FK et al. Heterologous expression of the mevalonic acid pathway in cyanobacteria enhances endogenous carbon partitioning to isoprene. 2014 Mol Plant pmid:24157609
Fu Z et al. Exometabolome analysis reveals hypoxia at the up-scaling of a Saccharomyces cerevisiae high-cell density fed-batch biopharmaceutical process. 2014 Microb. Cell Fact. pmid:24593159
Zelcer N et al. The E3 ubiquitin ligase MARCH6 degrades squalene monooxygenase and affects 3-hydroxy-3-methyl-glutaryl coenzyme A reductase and the cholesterol synthesis pathway. 2014 Mol. Cell. Biol. pmid:24449766
Kiser PD et al. Chemistry of the retinoid (visual) cycle. 2014 Chem. Rev. pmid:23905688
Rachner TD et al. Dickkopf-1 is regulated by the mevalonate pathway in breast cancer. 2014 Breast Cancer Res. pmid:24528599
Qi XF et al. HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway. 2013 Cell Death Dis pmid:23449454
Tyurin M Gene replacement and elimination using λRed- and FLP-based tool to re-direct carbon flux in acetogen biocatalyst during continuous CO₂/H₂ blend fermentation. 2013 J. Ind. Microbiol. Biotechnol. pmid:23649912
Chen B et al. Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction. 2013 Cell. Physiol. Biochem. pmid:24356578
Dellas N et al. Discovery of a metabolic alternative to the classical mevalonate pathway. 2013 Elife pmid:24327557
Lesma E et al. Chromatin remodeling by rosuvastatin normalizes TSC2-/meth cell phenotype through the expression of tuberin. 2013 J. Pharmacol. Exp. Ther. pmid:23426956