Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Celiac Disease D002446 16 associated lipids
Biliary Fistula D001658 13 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Peutz-Jeghers Syndrome D010580 2 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Authors Title Published Journal PubMed Link
pmid:8025334
Giron MD et al. Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8022795
Correll CC et al. Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. 1994 J. Biol. Chem. pmid:8021239
Gebhardt R et al. Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells. 1994 Biochim. Biophys. Acta pmid:8011681
Hiser L et al. ERG10 from Saccharomyces cerevisiae encodes acetoacetyl-CoA thiolase. 1994 J. Biol. Chem. pmid:7989303
Sinensky M et al. Expression of prelamin A but not mature lamin A confers sensitivity of DNA biosynthesis to lovastatin on F9 teratocarcinoma cells. 1994 J. Cell. Sci. pmid:7983180
Mallat A et al. Effect of simvastatin, an inhibitor of hydroxy-methylglutaryl coenzyme A reductase, on the growth of human Ito cells. 1994 Hepatology pmid:7982659
Hrab RV et al. Prevention of fluvastatin-induced toxicity, mortality, and cardiac myopathy in pregnant rats by mevalonic acid supplementation. 1994 Teratology pmid:7974251
Ortiz JA et al. Transfection of the ketogenic mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase cDNA into Mev-1 cells corrects their auxotrophy for mevalonate. 1994 J. Biol. Chem. pmid:7961793
Russell-Jones DL et al. The effect of growth hormone replacement on serum lipids, lipoproteins, apolipoproteins and cholesterol precursors in adult growth hormone deficient patients. 1994 Clin. Endocrinol. (Oxf) pmid:7955441
Dimster-Denk D et al. Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiae. 1994 Mol. Biol. Cell pmid:7949422
pmid:7935024
pmid:7926659
Ness GC et al. Effect of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7 alpha hydroxylase. 1994 Arch. Biochem. Biophys. pmid:7911291
Camp LA and Hofmann SL Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras. 1993 J. Biol. Chem. pmid:7901201
Johnson KA et al. In vivo formation of 25-hydroxycholesterol from endogenous cholesterol after a single meal, dietary cholesterol challenge. 1994 J. Lipid Res. pmid:7897321
Herold G et al. Influence of cholesterol supply on cell growth and differentiation in cultured enterocytes (CaCo-2). 1995 Digestion pmid:7895934
Pérez-Sala D et al. Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease. 1995 J. Biol. Chem. pmid:7890761
Chiloeches A et al. Effects of lovastatin on adenylyl cyclase activity and G proteins in GH4C1 cells. 1995 FEBS Lett. pmid:7890038
Munro E et al. Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis. 1994 Eur. J. Clin. Invest. pmid:7890015
Masters BA et al. In vitro myotoxicity of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, pravastatin, lovastatin, and simvastatin, using neonatal rat skeletal myocytes. 1995 Toxicol. Appl. Pharmacol. pmid:7878672
pmid:7876919
Straka MS and Panini SR Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate. 1995 Arch. Biochem. Biophys. pmid:7872789
Pfohl M et al. Acute and chronic effects on cholesterol biosynthesis of LDL-apheresis with or without concomitant HMG-CoA reductase inhibitor therapy. 1994 J. Lipid Res. pmid:7868973
pmid:7851471
Soma MR et al. In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin. 1995 Cancer Res. pmid:7834630
Shipton CA et al. Isoprenylation of plant proteins in vivo. Isoprenylated proteins are abundant in the mitochondria and nuclei of spinach. 1995 J. Biol. Chem. pmid:7822281
Sekler MS and Simoni RD Mutation in the lumenal part of the membrane domain of HMG-CoA reductase alters its regulated degradation. 1995 Biochem. Biophys. Res. Commun. pmid:7818519
Ortiz MB et al. Mevalonate dependency of the early cell cycle mitogenic response to epidermal growth factor and prostaglandin F2 alpha in Swiss mouse 3T3 cells. 1995 J. Cell. Physiol. pmid:7814446
Cummings MH and Watts GF Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in cholesteryl ester storage disease. 1995 Clin. Chem. pmid:7813057
Thelin A et al. Effect of squalestatin 1 on the biosynthesis of the mevalonate pathway lipids. 1994 Biochim. Biophys. Acta pmid:7811707
Sagami H et al. A novel type of protein modification by isoprenoid-derived materials. Diphytanylglycerylated proteins in Halobacteria. 1995 J. Biol. Chem. pmid:7797461
Schootemeijer A et al. Relation between membrane fluidity and signal transduction in the human megakaryoblastic cell line MEG-01. 1995 Biochim. Biophys. Acta pmid:7794941
Crick DC et al. Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells. 1995 Biochem. Biophys. Res. Commun. pmid:7794274
Corsini A et al. Pharmacology of competitive inhibitors of HMG-CoA reductase. 1995 Pharmacol. Res. pmid:7784310
Re EB et al. Co-expression of native and introduced genes reveals cryptic regulation of HMG CoA reductase expression in Arabidopsis. 1995 Plant J. pmid:7773308
Aspbury RA et al. Lipid modification of signal-transducing polypeptides in the free-living nematode Caenorhabditis elegans. 1995 Biochem. Soc. Trans. pmid:7758740
Appelkvist EL et al. Regulation of coenzyme Q biosynthesis. 1994 Mol. Aspects Med. pmid:7752843
Dimster-Denk D et al. Control of RAS mRNA level by the mevalonate pathway. 1995 Mol. Biol. Cell pmid:7749195
Sasseville AM and Raymond Y Lamin A precursor is localized to intranuclear foci. 1995 J. Cell. Sci. pmid:7738105
Massey LK et al. Branched-chain amino acid catabolism in bacteria. 1976 Bacteriol Rev pmid:773366
Ishikawa S et al. Simvastatin inhibits the cellular signaling and proliferative action of arginine vasopressin in cultured rat glomerular mesangial cells. 1995 Endocrinology pmid:7720643
Cummings MH et al. Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in obesity: a stable isotope study. 1995 Clin. Sci. pmid:7720348
Cuthbert JA and Lipsky PE Suppression of the proliferation of Ras-transformed cells by fluoromevalonate, an inhibitor of mevalonate metabolism. 1995 Cancer Res. pmid:7712482
Lala A et al. The effects of insulin on plasma mevalonate concentrations in man. 1994 Ann. Nutr. Metab. pmid:7710260
pmid:7672316
Bernini F et al. HMG-CoA reductase inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages. 1995 Arterioscler. Thromb. Vasc. Biol. pmid:7670949
Doerner KC et al. Regulation of cholesterol 7 alpha-hydroxylase expression by sterols in primary rat hepatocyte cultures. 1995 J. Lipid Res. pmid:7665995
Inglese J Prenylation-dependent targeting of G-protein-coupled receptor kinases. 1995 Meth. Enzymol. pmid:7651147
pmid:7651146