| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Smith-Lemli-Opitz Syndrome | D019082 | 7 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pomerantz KB et al. | G-protein-mediated signaling in cholesterol-enriched arterial smooth muscle cells. 2. Role of protein kinase C-delta in the regulation of eicosanoid production. | 1997 | Biochemistry | pmid:9235999 |
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| pmid:9226547 | ||||
| Flint OP et al. | HMG CoA reductase inhibitor-induced myotoxicity: pravastatin and lovastatin inhibit the geranylgeranylation of low-molecular-weight proteins in neonatal rat muscle cell culture. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9221829 |
| Flint OP et al. | Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9221828 |
| Lasa M et al. | Lovastatin decreases prolactin and growth hormone gene expression in GH4C1 cells through a cAMP dependent mechanism. | 1997 | Mol. Cell. Endocrinol. | pmid:9220025 |
| pmid:921298 | ||||
| Spencer TA et al. | Feasibility of an immunoassay for mevalonolactone. | 1997 | Bioorg. Med. Chem. | pmid:9208099 |
| Chan PC et al. | Lovastatin increases surface low density lipoprotein receptor expression by retarding the receptor internalization rate in proliferating lymphocytes. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9196047 |
| pmid:9191394 | ||||
| Raiteri M et al. | Pharmacological control of the mevalonate pathway: effect on arterial smooth muscle cell proliferation. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9190847 |
| Fuhrman B et al. | Hypocholesterolemic effect of lycopene and beta-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9168909 |
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| Amin D et al. | RPR 107393, a potent squalene synthase inhibitor and orally effective cholesterol-lowering agent: comparison with inhibitors of HMG-CoA reductase. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9152381 |
| Anouja F et al. | The cytotoxicity of the parvovirus minute virus of mice nonstructural protein NS1 is related to changes in the synthesis and phosphorylation of cell proteins. | 1997 | J. Virol. | pmid:9151861 |
| Herawati E and Ishizaki A | Optimization of the culture medium for growth and the kinetics of lactate fermentation by Pediococcus sp. ISK-1. | 1997 | Biosci. Biotechnol. Biochem. | pmid:9145518 |
| Padayatty SJ et al. | Lovastatin-induced apoptosis in prostate stromal cells. | 1997 | J. Clin. Endocrinol. Metab. | pmid:9141529 |
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| pmid:9089010 | ||||
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| Colli S et al. | Vastatins inhibit tissue factor in cultured human macrophages. A novel mechanism of protection against atherothrombosis. | 1997 | Arterioscler. Thromb. Vasc. Biol. | pmid:9081680 |
| pmid:9070894 | ||||
| Scoppola A et al. | Plasma mevalonate concentrations in uremic patients. | 1997 | Kidney Int. | pmid:9067929 |
| pmid:9056235 | ||||
| BeytÃa ED and Porter JW | Biochemistry of polyisoprenoid biosynthesis. | 1976 | Annu. Rev. Biochem. | pmid:9026 |
| Edwards PA et al. | Preferential uptake and utilization of mevalonolactone over mevalonate for sterol biosynthesis in isolated rat hepatocytes. | 1977 | Biochim. Biophys. Acta | pmid:901801 |
| Peffley DM and Gayen AK | Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level. | 1997 | Arch. Biochem. Biophys. | pmid:9016820 |
| Stout RW | The effect of insulin and glucose on sterol synthesis in cultured rat arterial smooth muscle cells. | 1977 | Atherosclerosis | pmid:901624 |
| Lichtenthaler HK et al. | Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate-independent pathway. | 1997 | FEBS Lett. | pmid:9009212 |
| pmid:900481 | ||||
| Chiloeches A et al. | Effect of mevalonate availability on the association of G-protein alpha-subunits with the plasma membrane in GH4C1 cells. | 1997 | FEBS Lett. | pmid:9003808 |
| Hirai A et al. | Geranylgeranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progression from G1 to S phase in growth-stimulated rat FRTL-5 cells. | 1997 | J. Biol. Chem. | pmid:8995216 |
| Spicer LJ et al. | Insulin-like growth factor I enhancement of steroidogenesis by bovine granulosa cells and thecal cells: dependence on de novo cholesterol synthesis. | 1996 | J. Endocrinol. | pmid:8994382 |
| Krisans SK | Cell compartmentalization of cholesterol biosynthesis. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8993542 |
| Shoda J et al. | Simultaneous determination of plasma mevalonate and 7alpha-hydroxy-4-cholesten-3-one levels in hyperlipoproteinemia: convenient indices for estimating hepatic defects of cholesterol and bile acid syntheses and biliary cholesterol supersaturation. | 1997 | Hepatology | pmid:8985259 |
| Sato-Suzuki I and Murota S | Simvastatin inhibits the division and induces neurite-like outgrowth in PC12 cells. | 1996 | Neurosci. Lett. | pmid:8977139 |
| Bandoh T et al. | Inhibitory effect of fluvastatin at doses insufficient to lower serum lipids on the catheter-induced thickening of intima in rabbit femoral artery. | 1996 | Eur. J. Pharmacol. | pmid:8960862 |
| pmid:8957210 | ||||
| pmid:8946387 | ||||
| Field H et al. | Characterisation of protein isoprenylation in procyclic form Trypanosoma brucei. | 1996 | Mol. Biochem. Parasitol. | pmid:8943151 |
| Goalstone ML and Draznin B | Effect of insulin on farnesyltransferase activity in 3T3-L1 adipocytes. | 1996 | J. Biol. Chem. | pmid:8910345 |
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| pmid:8907210 | ||||
| Lindenthal B et al. | Urinary excretion of mevalonic acid as an indicator of cholesterol synthesis. | 1996 | J. Lipid Res. | pmid:8906596 |
| pmid:8902853 | ||||
| Ramsey RB and Fredericks M | Effect of hypocholesterolemic agents on central nervous system cholesterol biosynthesis. I. Zuclomiphene. | 1977 | Biochem. Pharmacol. | pmid:889582 |
| MartÃn D et al. | Inhibition of vitellogenin production by allatostatin in the German cockroach. | 1996 | Mol. Cell. Endocrinol. | pmid:8892320 |
| Honda A et al. | Effect of YM 9429, a potent teratogen, on cholesterol biosynthesis in cultured cells and rat liver microsomes. | 1996 | Steroids | pmid:8883221 |
| Kurakata S et al. | Effects of different inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, pravastatin sodium and simvastatin, on sterol synthesis and immunological functions in human lymphocytes in vitro. | 1996 | Immunopharmacology | pmid:8880225 |
| Parmryd I and Dallner G | Organization of isoprenoid biosynthesis. | 1996 | Biochem. Soc. Trans. | pmid:8878825 |
| Jones PJ et al. | Dietary cholesterol feeding suppresses human cholesterol synthesis measured by deuterium incorporation and urinary mevalonic acid levels. | 1996 | Arterioscler. Thromb. Vasc. Biol. | pmid:8857917 |
| pmid:8835365 | ||||
| Reimann FM et al. | Reduced cholesterol esterification in CaCo-2 cells by indirect action of pravastatin. | 1996 | Atherosclerosis | pmid:8831928 |
| Satoh T et al. | The effects of pravastatin, an HMG-CoA reductase inhibitor, on cell viability and DNA production of rat hepatocytes. | 1996 | Life Sci. | pmid:8831797 |
| Nantais DE et al. | Prenylation of an interferon-gamma-induced GTP-binding protein: the human guanylate binding protein, huGBP1. | 1996 | J. Leukoc. Biol. | pmid:8830800 |
| Knöss W and Reuter B | Biosynthesis of [14C]geranylgeranyldiphosphate by a prenyl transferase system from a mutant strain of Gibberella fujikuroi. | 1996 | Anal. Biochem. | pmid:8811910 |
| McGee TP et al. | Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis. | 1996 | J. Biol. Chem. | pmid:8810339 |
| Naoumova RP et al. | Plasma mevalonic acid, an index of cholesterol synthesis in vivo, and responsiveness to HMG-CoA reductase inhibitors in familial hypercholesterolaemia. | 1996 | Atherosclerosis | pmid:8808497 |
| pmid:8807496 | ||||
| Taylor GW et al. | Excursions in biomedical mass spectrometry. | 1996 | Br J Clin Pharmacol | pmid:8807152 |
| pmid:8793275 | ||||
| Andersson M et al. | Age-dependent modifications in the metabolism of mevalonate pathway lipids in rat brain. | 1995 | Mech. Ageing Dev. | pmid:8789251 |
| Miquel K et al. | Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8780704 |
| Domenech CE et al. | Separate compartments for the production of sterols, carotenoids and gibberellins in Gibberella fujikuroi. | 1996 | Eur. J. Biochem. | pmid:8774718 |
| Nishio E et al. | 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor impairs cell p4fferentiation in cultured adipogenic cells (3T3-L1). | 1996 | Eur. J. Pharmacol. | pmid:8773465 |
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| Guyton JR et al. | Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants. | 1995 | Atherosclerosis | pmid:8770318 |
| Ku EC | Regulation of fatty acid biosynthesis by intermediates of the cholesterol biosynthetic pathway. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8769113 |
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| pmid:8750242 | ||||
| pmid:8747489 | ||||
| Sliwowski JK et al. | The in vivo biosynthesis of cholesterol from (3RS,2R) [2-14C,2-3H]mevalonic acid in the brains of rats on normal and protein deficient diets. The stereochemistry of tritium atoms at C-7 and C-15. | 1977 | J. Neurochem. | pmid:874493 |
| Lakshmanan MR and Veech RL | Measurement of rate of rat liver sterol synthesis in vivo using tritiated water. | 1977 | J. Biol. Chem. | pmid:873910 |
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| pmid:8702422 | ||||
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| pmid:8692019 | ||||
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| Carlberg M et al. | Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth. | 1996 | J. Biol. Chem. | pmid:8663239 |
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| Keller RK et al. | Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. | 1996 | Arch. Biochem. Biophys. | pmid:8645011 |
| Carlberg M and Larsson O | Stimulatory effect of PDGF on HMG-CoA reductase activity and N-linked glycosylation contributes to increased expression of IGF-1 receptors in human fibroblasts. | 1996 | Exp. Cell Res. | pmid:8635486 |
| James G et al. | Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8633088 |
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| Alaei P et al. | Inhibition of protein prenylation down-regulates signalling by inflammatory mediators in human keratinocytes. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8630058 |
| Meigs TE et al. | Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo. | 1996 | J. Biol. Chem. | pmid:8626470 |
| pmid:8617335 | ||||
| Faas FH et al. | Unsaturated fatty acyl-CoA inhibition of cholesterol synthesis in vitro. | 1977 | Biochim. Biophys. Acta | pmid:861236 |
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