DiNicolantonio JJ |
CoQ10 and L-carnitine for statin myalgia? |
2012 |
Expert Rev Cardiovasc Ther |
pmid:23190071
|
Aliferis KA and Jabaji S |
FT-ICR/MS and GC-EI/MS metabolomics networking unravels global potato sprout's responses to Rhizoctonia solani infection. |
2012 |
PLoS ONE |
pmid:22880040
|
Zaidi N et al. |
ATP-citrate lyase: a key player in cancer metabolism. |
2012 |
Cancer Res. |
pmid:22787121
|
Matsuoka T et al. |
An ultrasensitive enzymatic method for measuring mevalonic acid in serum. |
2012 |
J. Lipid Res. |
pmid:22715156
|
Liu D et al. |
The genome of Ganoderma lucidum provides insights into triterpenes biosynthesis and wood degradation [corrected]. |
2012 |
PLoS ONE |
pmid:22567134
|
Yang J et al. |
Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. |
2012 |
PLoS ONE |
pmid:22558074
|
Shi Z and Ruvkun G |
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22396595
|
Thurnher M et al. |
Novel aspects of mevalonate pathway inhibitors as antitumor agents. |
2012 |
Clin. Cancer Res. |
pmid:22529099
|
Hong SY et al. |
Isoprene hydrocarbons production upon heterologous transformation of Saccharomyces cerevisiae. |
2012 |
J. Appl. Microbiol. |
pmid:22519412
|
Iwata A et al. |
Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells. |
2012 |
Clin. Exp. Immunol. |
pmid:22471285
|
Luvai A et al. |
Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease. |
2012 |
Clin Med Insights Cardiol |
pmid:22442638
|
Lachenmeier DW et al. |
NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements. |
2012 |
Chin Med |
pmid:22439629
|
Mosqueda J et al. |
Current advances in detection and treatment of babesiosis. |
2012 |
Curr. Med. Chem. |
pmid:22360483
|
Hyldgaard M et al. |
Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. |
2012 |
Front Microbiol |
pmid:22291693
|
Ma Y et al. |
Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. |
2012 |
J. Exp. Bot. |
pmid:22291132
|
Keizer HG |
The "Mevalonate hypothesis": a cholesterol-independent alternative for the etiology of atherosclerosis. |
2012 |
Lipids Health Dis |
pmid:23122424
|
Freed-Pastor WA et al. |
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. |
2012 |
Cell |
pmid:22265415
|
Angaman DM et al. |
Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts. |
2012 |
Plant Methods |
pmid:22243738
|
Yano K |
Lipid metabolic pathways as lung cancer therapeutic targets: a computational study. |
2012 |
Int. J. Mol. Med. |
pmid:22211244
|
Shimane M et al. |
Mevalonate-dependent enzymatic synthesis of amorphadiene driven by an ATP-regeneration system using polyphosphate kinase. |
2012 |
Biosci. Biotechnol. Biochem. |
pmid:22878192
|
Mans RA et al. |
Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. |
2012 |
Neuroscience |
pmid:22192838
|
Fu X et al. |
Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits. |
2012 |
J. Exp. Bot. |
pmid:21994170
|
Murphy LA et al. |
Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation. |
2012 |
Toxicol. Appl. Pharmacol. |
pmid:22361350
|
Zhou K et al. |
Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production. |
2012 |
PLoS ONE |
pmid:23133596
|
Fuhrmeister J et al. |
Prooxidative toxicity and selenoprotein suppression by cerivastatin in muscle cells. |
2012 |
Toxicol. Lett. |
pmid:23092657
|
Scalcinati G et al. |
Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae. |
2012 |
Microb. Cell Fact. |
pmid:22938570
|
Li X et al. |
Differential mRNA expression of seven genes involved in cholesterol metabolism and transport in the liver of atherosclerosis-susceptible and -resistant Japanese quail strains. |
2012 |
Genet. Sel. Evol. |
pmid:22682430
|
Baadhe RR et al. |
Development of petri net-based dynamic model for improved production of farnesyl pyrophosphate by integrating mevalonate and methylerythritol phosphate pathways in yeast. |
2012 |
Appl. Biochem. Biotechnol. |
pmid:22350871
|
Panicker SP et al. |
Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in cicatricial alopecia. |
2012 |
PLoS ONE |
pmid:22685570
|
Guo H et al. |
Rosuvastatin may modulate insulin signaling and inhibit atherogenesis beyond its plasma cholesterol-lowering effect in insulin-resistant mice. |
2012 |
Cardiovasc Drugs Ther |
pmid:22918601
|
Trapani L et al. |
3-hydroxy 3-methylglutaryl coenzyme A reductase inhibition impairs muscle regeneration. |
2012 |
J. Cell. Biochem. |
pmid:22274883
|
Nürenberg G and Volmer DA |
The analytical determination of isoprenoid intermediates from the mevalonate pathway. |
2012 |
Anal Bioanal Chem |
pmid:21789486
|
Garcia-Ruiz C et al. |
Statins and protein prenylation in cancer cell biology and therapy. |
2012 |
Anticancer Agents Med Chem |
pmid:22413970
|
Wu S et al. |
Engineering triterpene metabolism in tobacco. |
2012 |
Planta |
pmid:22729821
|
Hu W et al. |
Statins synergize dexamethasone-induced adipocyte fatty acid binding protein expression in macrophages. |
2012 |
Atherosclerosis |
pmid:22503826
|
Henriquez MA et al. |
Effects of glucans and eicosapentaenoic acid on differential regulation of phenylpropanoid and mevalonic pathways during potato response to Phytophthora infestans. |
2012 |
Plant Physiol. Biochem. |
pmid:22922112
|
Song AA et al. |
Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production. |
2012 |
PLoS ONE |
pmid:23300671
|
Partow S et al. |
Reconstruction and evaluation of the synthetic bacterial MEP pathway in Saccharomyces cerevisiae. |
2012 |
PLoS ONE |
pmid:23285068
|
Yang D et al. |
Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots. |
2012 |
PLoS ONE |
pmid:23209548
|
Hussain MS et al. |
Current approaches toward production of secondary plant metabolites. |
2012 |
J Pharm Bioallied Sci |
pmid:22368394
|
Iguchi K |
[Effect of bisphosphonates on anticancer activity in prostate cancer cells]. |
2012 |
Yakugaku Zasshi |
pmid:23023419
|
Haines BE et al. |
Molecular modeling of the reaction pathway and hydride transfer reactions of HMG-CoA reductase. |
2012 |
Biochemistry |
pmid:22971202
|
Coscia M et al. |
Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells. |
2012 |
Blood |
pmid:22932792
|
Malenda A et al. |
Statins impair glucose uptake in tumor cells. |
2012 |
Neoplasia |
pmid:22577346
|
Garjani A et al. |
Ambivalent effects of atorvastatin on angiogenesis, epidermal cell proliferation and tumorgenesis in animal models. |
2012 |
Iran. Biomed. J. |
pmid:22801278
|
Ginestier C et al. |
p53 and cancer stem cells: the mevalonate connexion. |
2012 |
Cell Cycle |
pmid:22751434
|
Roy A et al. |
Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease. |
2012 |
PLoS ONE |
pmid:22723850
|
Ghavami S et al. |
Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts. |
2012 |
Cell Death Dis |
pmid:22717585
|
Ohsawa M et al. |
Effect of spinally administered simvastatin on the formalin-induced nociceptive response in mice. |
2012 |
J. Pharmacol. Sci. |
pmid:22510521
|
Khasnavis S and Pahan K |
Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. |
2012 |
J Neuroimmune Pharmacol |
pmid:21701815
|
Plée-Gautier E et al. |
Statins increase cytochrome P450 4F3-mediated eicosanoids production in human liver cells: a PXR dependent mechanism. |
2012 |
Biochem. Pharmacol. |
pmid:22634049
|
Paintlia AS et al. |
Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis. |
2012 |
Am. J. Pathol. |
pmid:22796435
|
Drabkin HA and Gemmill RM |
Cholesterol and the development of clear-cell renal carcinoma. |
2012 |
Curr Opin Pharmacol |
pmid:22939900
|
Rad SA et al. |
Type 2 IDI performs better than type 1 for improving lycopene production in metabolically engineered E. coli strains. |
2012 |
World J. Microbiol. Biotechnol. |
pmid:22806807
|
Campia I et al. |
Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes. |
2012 |
Biochem. J. |
pmid:22845468
|
Fatima T et al. |
Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. |
2012 |
PLoS ONE |
pmid:22558083
|
Zhang B et al. |
Interference in mevalonate pathway ameliorates homocysteine-induced endothelium-dysfunction. |
2012 |
Eur. J. Pharmacol. |
pmid:22796672
|
Conrado RJ et al. |
DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. |
2012 |
Nucleic Acids Res. |
pmid:22021385
|
Roullet JB et al. |
No evidence for mevalonate shunting in moderately affected children with Smith-Lemli-Opitz syndrome. |
2012 |
J. Inherit. Metab. Dis. |
pmid:22391996
|
Barta ML et al. |
Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. |
2012 |
Biochemistry |
pmid:22734632
|
Jiang Q et al. |
Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide. |
2012 |
Int. J. Cancer |
pmid:21400505
|
Yokota K et al. |
Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners. |
2011 Jan-Feb |
Clin. Exp. Rheumatol. |
pmid:21345291
|
Huang SH et al. |
Imaging of zebrafish in vivo with second-harmonic generation reveals shortened sarcomeres associated with myopathy induced by statin. |
2011 |
PLoS ONE |
pmid:21966365
|
Singh NK et al. |
12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation. |
2011 |
Blood |
pmid:21841162
|
Yu F et al. |
Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis. |
2011 |
Cell. Mol. Life Sci. |
pmid:20730551
|
Luo H et al. |
Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. |
2011 |
BMC Genomics |
pmid:22369100
|
Nes WD |
Biosynthesis of cholesterol and other sterols. |
2011 |
Chem. Rev. |
pmid:21902244
|
Tijerino A et al. |
Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings. |
2011 |
Toxins (Basel) |
pmid:22069764
|
Wang H et al. |
Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism. |
2011 |
J. Immunol. |
pmid:22013129
|
Ali OF et al. |
Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. |
2011 |
Respir. Res. |
pmid:21999923
|
Bergman P et al. |
Studies on the antibacterial effects of statins--in vitro and in vivo. |
2011 |
PLoS ONE |
pmid:21912631
|
Emma F et al. |
Renal mitochondrial cytopathies. |
2011 |
Int J Nephrol |
pmid:21811680
|
Katuru R et al. |
Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. |
2011 |
Exp. Biol. Med. (Maywood) |
pmid:21540247
|
Waldron J and Webster C |
Liquid chromatography-tandem mass spectrometry method for the measurement of serum mevalonic acid: a novel marker of hydroxymethylglutaryl coenzyme A reductase inhibition by statins. |
2011 |
Ann. Clin. Biochem. |
pmid:21355014
|
Jeon JG et al. |
Natural products in caries research: current (limited) knowledge, challenges and future perspective. |
2011 |
Caries Res. |
pmid:21576957
|
Scheller EL et al. |
Bisphosphonates inhibit expression of p63 by oral keratinocytes. |
2011 |
J. Dent. Res. |
pmid:21551338
|
Kishi T |
Mevalonate pathway is a novel target for hypertension. |
2011 |
Circ. J. |
pmid:21532185
|
Sakamoto K et al. |
Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes. |
2011 |
BMC Musculoskelet Disord |
pmid:21524281
|
Han J et al. |
Alteration of enzyme expressions in mevalonate pathway: possible role for cardiovascular remodeling in spontaneously hypertensive rats. |
2011 |
Circ. J. |
pmid:21467659
|
Siddals KW et al. |
Apposite insulin-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization. |
2011 |
J. Biol. Chem. |
pmid:21454560
|
Mongélard G et al. |
Measurement of carbon flux through the MEP pathway for isoprenoid synthesis by (31)P-NMR spectroscopy after specific inhibition of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate reductase. Effect of light and temperature. |
2011 |
Plant Cell Environ. |
pmid:21443577
|
Zhang B et al. |
A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. |
2011 |
Biochemistry |
pmid:21438569
|
Kim RH et al. |
Bisphosphonates induce senescence in normal human oral keratinocytes. |
2011 |
J. Dent. Res. |
pmid:21427353
|
Kyathanahalli CN and Kowluru A |
A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGEâ‚‚. |
2011 |
Biochem. Pharmacol. |
pmid:21406184
|
Kim KH et al. |
Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants. |
2011 |
Drug Metab. Dispos. |
pmid:20962060
|
Miziorko HM |
Enzymes of the mevalonate pathway of isoprenoid biosynthesis. |
2011 |
Arch. Biochem. Biophys. |
pmid:20932952
|
Tsuyuki R et al. |
Enhancement of trichothecene production in Fusarium graminearum by cobalt chloride. |
2011 |
J. Agric. Food Chem. |
pmid:21299216
|
Li YY et al. |
Zoledronic acid induces cell-cycle prolongation in murine lung cancer cells by perturbing cyclin and Ras expression. |
2011 |
Anticancer Drugs |
pmid:20926944
|
Nilsson S et al. |
Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells. |
2011 |
Cancer Lett. |
pmid:21356574
|
Liu Q et al. |
Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana. |
2011 |
PLoS ONE |
pmid:21858047
|
Jouneau S et al. |
Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. |
2011 |
PLoS ONE |
pmid:21826199
|
Sakai H and Heike T |
[Hyperimmunoglobulinemia D and periodic fever syndrome]. |
2011 |
Nihon Rinsho Meneki Gakkai Kaishi |
pmid:22041426
|
Issat T et al. |
Antitumor effects of the combination of cholesterol reducing drugs. |
2011 |
Oncol. Rep. |
pmid:21491092
|
Goto T et al. |
Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. |
2011 |
Biochem. J. |
pmid:21605082
|
Duke SO and Dayan FE |
Modes of action of microbially-produced phytotoxins. |
2011 |
Toxins (Basel) |
pmid:22069756
|
Musso A et al. |
Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survival. |
2011 |
Haematologica |
pmid:20884711
|
Schaafsma D et al. |
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. |
2011 |
Respir. Res. |
pmid:21864337
|
Simkin AJ et al. |
Peroxisomal localisation of the final steps of the mevalonic acid pathway in planta. |
2011 |
Planta |
pmid:21655959
|
Barta ML et al. |
Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. |
2011 |
J. Biol. Chem. |
pmid:21561869
|
Yanae M et al. |
Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. |
2011 |
J. Exp. Clin. Cancer Res. |
pmid:21831290
|