Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Peutz-Jeghers Syndrome D010580 2 associated lipids
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Biliary Fistula D001658 13 associated lipids
Celiac Disease D002446 16 associated lipids
Xanthomatosis D014973 17 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Shamburek RD et al. Intracellular trafficking of the free cholesterol derived from LDL cholesteryl ester is defective in vivo in Niemann-Pick C disease: insights on normal metabolism of HDL and LDL gained from the NP-C mutation. 1997 J. Lipid Res. pmid:9458266
Natarajan R et al. Molecular cloning of the promoter for rat hepatic neutral cholesterol ester hydrolase: evidence for transcriptional regulation by sterols. 1998 Biochem. Biophys. Res. Commun. pmid:9480812
Lange BM et al. A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9482845
Ellsworth JL and Starr JR Inhibition of acyl coenzyme A:cholesterol acyltransferase blocks esterification but not uptake of cholesterol in Caco-2 cells. 1998 Metab. Clin. Exp. pmid:9500571
Sul D and Kaneshiro ES Ubiquinone synthesis by Pneumocystis carinii: incorporation of radiolabeled polyprenyl chain and benzoquinone ring precursors. 1997 Nov-Dec J. Eukaryot. Microbiol. pmid:9508445
Rosenthal RS and Rodwell VW Purification and characterization of the heteromeric transcriptional activator MvaT of the Pseudomonas mevalonii mvaAB operon. 1998 Protein Sci. pmid:9514272
Kalra VK and Blankenhorn DH Abnormal activation of sterol synthesis in lymphocytes of atherosclerotic-susceptible pigeons and heterozygous familial hypercholesterolemic patients. 1976 Biochim. Biophys. Acta pmid:952994
Disch A et al. Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. 1998 Biochem. J. pmid:9531505
Laufs U et al. Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. 1998 Circulation pmid:9537338
Gopalaswamy UV and Aiyar AS Actinomycin D-induced enhancement of ubiquinone biosynthesis in rat. 1976 Chem. Biol. Interact. pmid:954142
Luckman SP et al. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. 1998 J. Bone Miner. Res. pmid:9556058
Kaur M et al. Receptor-Ck-dependent regulation of genes involved in the cell cycle. 1998 Mol. Cell. Biochem. pmid:9562250
Coutant KD et al. Fluvastatin enhances receptor-stimulated intracellular Ca2+ release in human keratinocytes. 1998 Biochem. Biophys. Res. Commun. pmid:9571146
Visioli F et al. Ethanol enhances cholesterol synthesis and secretion in human hepatomal cells. 1998 Alcohol pmid:9590514
Orihara N et al. Studies on the biosynthesis of terpenoidal compounds produced by actinomycetes. 2. Biosynthesis of carquinostatin B via the non-mevalonate pathway in Streptomyces exfoliatus. 1997 J. Antibiot. pmid:9592576
Singh I et al. Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy. 1998 FEBS Lett. pmid:9600263
Rubins JB et al. Lovastatin induces apoptosis in malignant mesothelioma cells. 1998 Am. J. Respir. Crit. Care Med. pmid:9603146
Crick DC et al. Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. 1998 J. Neurochem. pmid:9603204
Melnykovych G et al. Inhibition of cholesterol biosynthesis in HeLa cells by glucocorticoids. 1976 Biochem. Biophys. Res. Commun. pmid:962938
Mitropoulos KA and Gibbons GF Effect of triarimol on cholesterol biosynthesis in rat-liver subcellular. 1976 Biochem. Biophys. Res. Commun. pmid:962959