| MeSH term | MeSH ID | Detail |
|---|---|---|
| Peutz-Jeghers Syndrome | D010580 | 2 associated lipids |
| Smith-Lemli-Opitz Syndrome | D019082 | 7 associated lipids |
| Hypergammaglobulinemia | D006942 | 9 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
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All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wolda SL and Glomset JA | Evidence for modification of lamin B by a product of mevalonic acid. | 1988 | J. Biol. Chem. | pmid:3283116 |
| Eggens I et al. | Cytidine 5'-triphosphate-dependent dolichol kinase and dolichol phosphatase activities and levels of dolichyl phosphate in microsomal fractions from highly differentiated human hepatomas. | 1988 | Cancer Res. | pmid:2836054 |
| Hu ZY et al. | Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3479785 |
| Saucier SE et al. | Accumulation of regulatory oxysterols, 32-oxolanosterol and 32-hydroxylanosterol in mevalonate-treated cell cultures. | 1987 | J. Biol. Chem. | pmid:3654653 |
| Elmberger PG et al. | In vitro and in vivo synthesis of dolichol and other main mevalonate products in various organs of the rat. | 1987 | Eur. J. Biochem. | pmid:3665910 |
| Hasumi K et al. | Overaccumulation of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase in a compactin(ML-236B)-resistant mouse cell line with defects in the regulation of its activity. | 1987 | Eur. J. Biochem. | pmid:3569277 |
| Larsson O | Role of biosynthesis of cholesterol and isoprenoid derivatives in regulation of G1 progression and cell proliferation of 3T6 cells. | 1987 | J. Cell. Physiol. | pmid:3667703 |
| Langan TJ and Volpe JJ | Cell cycle-specific requirement for mevalonate, but not for cholesterol, for DNA synthesis in glial primary cultures. | 1987 | J. Neurochem. | pmid:3648095 |
| Larsson O and Johansson BM | Mevalonic acid products as mediators of cell proliferation in simian virus 40-transformed 3T3 cells. | 1987 | Cancer Res. | pmid:3040232 |
| Sagami H and Lennarz WJ | Glycoprotein synthesis in Drosophila Kc cells. Biosynthesis of dolichol-linked saccharides. | 1987 | J. Biol. Chem. | pmid:3680215 |
| Zamir LO and Devor KA | Kinetic pulse-labeling study of Fusarium culmorum. Biosynthetic intermediates and dead-end metabolites. | 1987 | J. Biol. Chem. | pmid:3680199 |
| Choi YS et al. | Effects of short-term cholestyramine feeding on cholesterol metabolism in differently aged rats. | 1987 | Mech. Ageing Dev. | pmid:3431166 |
| Popják G and Meenan A | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase: search for the enzyme's repressor derived from mevalonate. | 1987 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:2892200 |
| Langan TJ and Volpe JJ | Oligodendroglial differentiation in glial primary cultures: requirement for mevalonate. | 1987 | J. Neurochem. | pmid:3033149 |
| Field FJ et al. | Regulation of cholesterol esterification by micellar cholesterol in CaCo-2 cells. | 1987 | J. Lipid Res. | pmid:3655559 |
| Shiomi K et al. | Biosynthesis of napyradiomycins. | 1987 | J. Antibiot. | pmid:3429338 |
| Beg ZH et al. | Modulation of the enzymic activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase by multiple kinase systems involving reversible phosphorylation: a review. | 1987 | Metab. Clin. Exp. | pmid:3306282 |
| Tabacik C et al. | Regulation of cholesterol biosynthesis at a stage after the 3-hydroxy-3-methylglutaryl-CoA reductase step, in normal and leukemic (L2C) guinea pig lymphocytes. | 1987 | Biochim. Biophys. Acta | pmid:3651496 |
| Appelkvist EL | In vitro labeling of peroxisomal cholesterol with radioactive precursors. | 1987 | Biosci. Rep. | pmid:3449127 |
| Burki E et al. | Endogenous sterol synthesis is not required for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by low density lipoprotein. | 1987 | J. Lipid Res. | pmid:3681144 |
| Ekström TJ et al. | The alpha-saturation and terminal events in dolichol biosynthesis. | 1987 | J. Biol. Chem. | pmid:3031061 |
| Marinier E et al. | Contribution of the shunt pathway of mevalonate metabolism to the regulation of cholesterol synthesis in rat liver. | 1987 | J. Biol. Chem. | pmid:3680279 |
| Feyereisen R and Farnsworth DE | Precursor supply for insect juvenile hormone III biosynthesis in a cockroach. | 1987 | J. Biol. Chem. | pmid:3818617 |
| Leijten L et al. | Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in mouse uterine epithelial cells. | 1987 | Biochem. J. | pmid:3032158 |
| Boogaard A et al. | Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in human hepatoma cell line Hep G2. Effects of inhibitors of cholesterol synthesis on enzyme activity. | 1987 | Biochem. J. | pmid:3036060 |
| Zamir LO et al. | Structure determination and biosynthesis of a novel metabolite of Fusarium culmorum, apotrichodiol. | 1987 | J. Biol. Chem. | pmid:3680200 |
| Trzaskos JM et al. | In situ accumulation of 3 beta-hydroxylanost-8-en-32-aldehyde in hepatocyte cultures. A putative regulator of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity. | 1987 | J. Biol. Chem. | pmid:3624256 |
| Rearick JI et al. | Human bronchial epithelial cells synthesize cholesterol sulfate during squamous differentiation in vitro. | 1987 | J. Cell. Physiol. | pmid:3480290 |
| Faust J and Krieger M | Expression of specific high capacity mevalonate transport in a Chinese hamster cell variant. | 1987 | J. Biol. Chem. | pmid:3643925 |
| Jensen E et al. | Cell-density-dependent uptake of chylomicron remnants in rat hepatocyte monolayers. Effects of compactin and mevalonic acid. | 1987 | Biochim. Biophys. Acta | pmid:3790613 |
| Tomoda H et al. | F-244 specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme A synthase. | 1987 | Biochim. Biophys. Acta | pmid:2891379 |
| Sablé-Amplis R et al. | Hepatic cholesterogenesis and cholesterol 7 alpha-hydroxylase activity in hamsters fed diets enriched with pectins and/or cholesterol. | 1987 | Ann. Nutr. Metab. | pmid:3827206 |
| Chiew YE et al. | Studies on pig liver mevalonate-5-diphosphate decarboxylase. | 1987 | Biochim. Biophys. Acta | pmid:2825791 |
| O'Neill HJ et al. | Identification of isoprenoid-type components in human expired air: a possible shunt pathway in sterol metabolism. | 1987 | Biomed. Chromatogr. | pmid:3147729 |
| Thompson SL et al. | Cholesterol synthesis in rat liver peroxisomes. Conversion of mevalonic acid to cholesterol. | 1987 | J. Biol. Chem. | pmid:3693362 |
| Havel C et al. | Isopentenoid synthesis in isolated embryonic Drosophila cells. Possible regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by shunted mevalonate carbon. | 1986 | J. Biol. Chem. | pmid:3733706 |
| Bruscalupi G et al. | Regulation of acyl CoA: cholesterol acyl transferase (ACAT) activity by mevalonate and cholesterol in isolated rat hepatocytes during perinatal development. | 1986 | Biosci. Rep. | pmid:3814768 |
| Borgford TJ et al. | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and lipid metabolism in a concanavalin A-resistant Chinese hamster ovary cell line. | 1986 | Arch. Biochem. Biophys. | pmid:3947077 |
| Ellsworth JL et al. | Very low and low density lipoprotein synthesis and secretion by the human hepatoma cell line Hep-G2: effects of free fatty acid. | 1986 | J. Lipid Res. | pmid:3021884 |
| Marrero PF et al. | Phosphorylation of HMG-CoA reductase induced by mevalonate accelerates its rate of degradation in isolated rat hepatocytes. | 1986 | FEBS Lett. | pmid:3512302 |
| Beg ZH et al. | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts by reversible phosphorylation: modulation of enzymatic activity by low density lipoprotein, sterols, and mevalonolactone. | 1986 | Arch. Biochem. Biophys. | pmid:3004340 |
| Cabrera JA et al. | Isoprenoid synthesis in Halobacterium halobium. Modulation of 3-hydroxy-3-methylglutaryl coenzyme a concentration in response to mevalonate availability. | 1986 | J. Biol. Chem. | pmid:3633268 |
| Rudney H and Sexton RC | Regulation of cholesterol biosynthesis. | 1986 | Annu. Rev. Nutr. | pmid:3524618 |
| Ekiel I et al. | Mevalonic acid is partially synthesized from amino acids in Halobacterium cutirubrum: a 13C nuclear magnetic resonance study. | 1986 | J. Bacteriol. | pmid:3700337 |
| Marco C et al. | Quantitative role of different embryonic tissues in mevalonate metabolism by sterol and nonsterol pathways. Relationship with enzyme activities of cholesterogenesis. | 1986 | Biochim. Biophys. Acta | pmid:3019412 |
| Marino M et al. | Enhanced production of dolichol, but not dolichyl phosphate, in the earliest stages of rat liver regeneration. | 1986 | Biosci. Rep. | pmid:3742013 |
| Pentchev PG et al. | The cholesterol storage disorder of the mutant BALB/c mouse. A primary genetic lesion closely linked to defective esterification of exogenously derived cholesterol and its relationship to human type C Niemann-Pick disease. | 1986 | J. Biol. Chem. | pmid:3949747 |
| Vuoristo M and Miettinen TA | Enhanced synthesis of cholesterol and its precursors in jejunal mucosa in coeliac disease. | 1986 | Gut | pmid:3957109 |
| Keller RK | The mechanism and regulation of dolichyl phosphate biosynthesis in rat liver. | 1986 | J. Biol. Chem. | pmid:3638306 |
| Herscovitz H et al. | Bile acid synthesis from HDL cholesterol and cholesterol ester by cultured chick embryo hepatocytes. | 1986 | Biochim. Biophys. Acta | pmid:3756203 |
| Cighetti G et al. | Effects of pantethine on cholesterol synthesis from mevalonate in isolated rat hepatocytes. | 1986 | Atherosclerosis | pmid:3707674 |
| Gupta A et al. | Modulation of regulatory oxysterol formation and low density lipoprotein suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity by ketoconazole. A role for cytochrome P-450 in the regulation of HMG-CoA reductase in rat intestinal epithelial cells. | 1986 | J. Biol. Chem. | pmid:3722155 |
| Hindy AM et al. | Sterol composition and biosynthesis in mouse salivary glands. | 1986 | Arch. Oral Biol. | pmid:3460541 |
| Larsson O and Zetterberg A | Effects of 25-hydroxycholesterol, cholesterol, and isoprenoid derivatives on the G1 progression in Swiss 3T3 cells. | 1986 | J. Cell. Physiol. | pmid:3760035 |
| Filipovic I and Buddecke E | Calmodulin antagonists stimulate LDL receptor synthesis in human skin fibroblasts. | 1986 | Biochim. Biophys. Acta | pmid:2418882 |
| Hoffmann G et al. | Mevalonic aciduria--an inborn error of cholesterol and nonsterol isoprene biosynthesis. | 1986 | N. Engl. J. Med. | pmid:3012338 |
| Nair N and Kurup CK | Investigations on the mechanism of the hypocholesterolemic action of diethylhexyl phthalate in rats. | 1986 | Biochem. Pharmacol. | pmid:3768033 |
| Golper TA et al. | The role of circulating mevalonate in nephrotic hypercholesterolemia in the rat. | 1986 | J. Lipid Res. | pmid:3794548 |
| Birnberg PR et al. | An improved enzymatic synthesis of labeled gibberellin A12-aldehyde and gibberellin A12. | 1986 | Anal. Biochem. | pmid:3754395 |
| Berger R et al. | Mevalonic aciduria: an inborn error of cholesterol biosynthesis? | 1985 | Clin. Chim. Acta | pmid:4053401 |
| Gillies PJ and Lee KP | Effects of hexafluoroacetone on Leydig cell steroidogenesis and spermatogenesis in the rat. | 1985 | Exp. Mol. Pathol. | pmid:3922783 |
| Saucier SE et al. | Identification of regulatory oxysterols, 24(S),25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts. | 1985 | J. Biol. Chem. | pmid:4055791 |
| Stone BG et al. | Regulation of rat biliary cholesterol secretion by agents that alter intrahepatic cholesterol metabolism. Evidence for a distinct biliary precursor pool. | 1985 | J. Clin. Invest. | pmid:4056052 |
| Peffley D and Sinensky M | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis by a non-sterol mevalonate-derived product in Mev-1 cells. Apparent translational control. | 1985 | J. Biol. Chem. | pmid:4019518 |
| Sherban DG et al. | Rat liver 3-hydroxy-3-methylglutaryl-CoA reductase. Catalysis of the reverse reaction and two half-reactions. | 1985 | J. Biol. Chem. | pmid:2413027 |
| Sinensky M and Logel J | Defective macromolecule biosynthesis and cell-cycle progression in a mammalian cell starved for mevalonate. | 1985 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2582409 |
| Wilton DC | The effect of excess mevalonic acid on ubiquinone and tetrahymanol biosynthesis in Tetrahymena pyriformis. | 1985 | Biochem. J. | pmid:3929773 |
| Okada K et al. | Effect of 4-(4'-chlorobenzyloxy)benzyl nicotinate (KCD-232) on cholesterol metabolism in rats. | 1985 | Biochem. Pharmacol. | pmid:4038342 |
| Patel DD and Knight BL | The effect of mevalonate on 3-hydroxy-3-methylglutaryl-CoA reductase activity and the absolute rate of cholesterol biosynthesis in human monocyte-derived macrophages. | 1985 | Eur. J. Biochem. | pmid:4065145 |
| Nave JF et al. | Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate. | 1985 | Biochem. J. | pmid:2986604 |
| Maltese WA and Aprille JR | Relation of mevalonate synthesis to mitochondrial ubiquinone content and respiratory function in cultured neuroblastoma cells. | 1985 | J. Biol. Chem. | pmid:3850088 |
| Goad LJ et al. | Sterols of ketoconazole-inhibited Leishmania mexicana mexicana promastigotes. | 1985 | Mol. Biochem. Parasitol. | pmid:4033689 |
| Maltese WA and Sheridan KM | Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis. | 1985 | J. Cell. Physiol. | pmid:3851809 |
| McNamara DJ et al. | Role of the kidneys in the metabolism of plasma mevalonate. Studies in humans and in rhesus monkeys. | 1985 | J. Clin. Invest. | pmid:4019781 |
| Ryder NS | Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent. | 1985 | Antimicrob. Agents Chemother. | pmid:4039119 |
| Goad LJ et al. | Effect of the allylamine antifungal drug SF 86-327 on the growth and sterol synthesis of Leishmania mexicana mexicana promastigotes. | 1985 | Biochem. Pharmacol. | pmid:4052119 |
| Watson JA et al. | Isoprenoid synthesis in isolated embryonic Drosophila cells. Sterol-independent regulatory signal molecule is distal to isopentenyl 1-pyrophosphates. | 1985 | J. Biol. Chem. | pmid:4055772 |
| Rilling HC | The mechanism of the condensation reactions of cholesterol biosynthesis. Fourth Morton lecture. | 1985 | Biochem. Soc. Trans. | pmid:4092833 |
| Gill JF et al. | Mevalonate utilization in Pseudomonas sp. M. Purification and characterization of an inducible 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1985 | J. Biol. Chem. | pmid:4019479 |
| Clarke CF et al. | Transcriptional regulation of the 3-hydroxy-3-methylglutaryl coenzyme A reductase gene in rat liver. | 1985 | J. Biol. Chem. | pmid:3850901 |
| Lee CS and O'Sullivan WJ | Improved procedures for the synthesis of phosphomevalonate and for the assay and purification of pig liver phosphomevalonate kinase. | 1985 | Biochim. Biophys. Acta | pmid:2983770 |
| Haro D et al. | Rat liver HMG CoA reductase, a glycoprotein of the endoplasmic reticulum, is in equilibrium between monomeric and dimeric forms. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3933506 |
| Herscovitz H and Tietz A | The availability of different sources of cholesterol for bile acid synthesis by cultured chick embryo hepatocytes. | 1985 | Biochim. Biophys. Acta | pmid:4041475 |
| Steen G et al. | Isoprenoid biosynthesis in multiple sclerosis. | 1985 | Acta Neurol. Scand. | pmid:4061053 |
| Popják G et al. | Role of mevalonate in regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured cells and their cytoplasts. | 1985 | J. Lipid Res. | pmid:2411835 |
| Lee CS and O'Sullivan WJ | The interaction of phosphorothioate analogues of ATP with phosphomevalonate kinase. Kinetic and 31P NMR studies. | 1985 | J. Biol. Chem. | pmid:2997186 |
| Deneris ES et al. | Acid-catalyzed formation of isoprene from a mevalonate-derived product using a rat liver cytosolic fraction. | 1985 | J. Biol. Chem. | pmid:3968076 |
| Weinstock SB et al. | The shunt pathway of mevalonate metabolism in the isolated perfused rat liver. | 1984 | J. Biol. Chem. | pmid:6430893 |
| Larson RA and Yachnin S | Mevalonic acid induces DNA synthesis in chronic lymphocytic leukemia cells. | 1984 | Blood | pmid:6610447 |
| Cuthbert JA and Lipsky PE | Modulation of human lymphocyte responses by low density lipoproteins (LDL): enhancement but not immunosuppression is mediated by LDL receptors. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6087331 |
| Herold G et al. | Cholesterol synthesis and esterification in cultured intestinal mucosa. Evidence for compartmentation. | 1984 | Biochim. Biophys. Acta | pmid:6567470 |
| Wilson JS et al. | Chronic ethanol feeding causes accumulation of serum cholesterol in rat pancreas. | 1984 | Exp. Mol. Pathol. | pmid:6510504 |
| Kreuz K and Kleinig H | Synthesis of prenyl lipids in cells of spinach leaf. Compartmentation of enzymes for formation of isopentenyl diphosphate. | 1984 | Eur. J. Biochem. | pmid:6086332 |
| Ryder NS et al. | Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans. | 1984 | Antimicrob. Agents Chemother. | pmid:6375557 |
| Panini SR et al. | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by oxysterol by-products of cholesterol biosynthesis. Possible mediators of low density lipoprotein action. | 1984 | J. Biol. Chem. | pmid:6736025 |
| Deneris ES et al. | In vitro biosynthesis of isoprene from mevalonate utilizing a rat liver cytosolic fraction. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6487307 |
| Wade DP et al. | Independent regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and chylomicron remnant receptor activities in rat liver. | 1984 | Biochem. J. | pmid:6324750 |
| Jeng I et al. | Insensitivity of ubiquinone biosynthesis in glioblastoma cells to an epileptogenic drug, U18666A. | 1984 | J. Neurochem. | pmid:6567656 |
| Yousef IM and Tuchweber B | Effect of lithocholic acid on cholesterol synthesis and transport in the rat liver. | 1984 | Biochim. Biophys. Acta | pmid:6509080 |
| Heacock AM et al. | Cholesterol synthesis and nerve regeneration. | 1984 | J. Neurochem. | pmid:6699648 |