Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Peutz-Jeghers Syndrome D010580 2 associated lipids
Smith-Lemli-Opitz Syndrome D019082 7 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Biliary Fistula D001658 13 associated lipids
Celiac Disease D002446 16 associated lipids
Xanthomatosis D014973 17 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

Download all related citations
Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
O'Brien DE and Rost WJ N-aralkyl-piperidyl carbanilates as hypocholesteremic agents. 1970 J Pharm Sci pmid:5416166
Cayen MN The effect of starvation and cholesterol feeding on intestinal cholesterol synthesis in the rat. 1969 Biochim. Biophys. Acta pmid:5364263
pmid:5362923
Van Aller RT et al. The mechanism of introduction of alkyl groups at carbon 24 of sterols. 3. The second one-carbon transfer and reduction. 1969 J. Biol. Chem. pmid:5361547
Hammond RK and White DC Formation of vitamin K2 isoprenologues by Staphylococcus aureus. 1969 J. Bacteriol. pmid:5354933
Ramm PJ and Caspi E The stereochemistry of tritium at carbon atoms 1, 7, and 15 in cholesterol derived from (3R,2R)-(2-3H)-mevalonic acid. 1969 J. Biol. Chem. pmid:5350956
De Matteis F Liver cholesterol metabolism following trauma. Evidence for increased rate of cholesterol synthesis and breakdown. 1969 Biochim. Biophys. Acta pmid:5349601
Goad LJ et al. Incorporation of (2-14C, (5r)-5-3H1) mevalonic acid into cholesterol by a rat liver homogenate and into beta-sitosterol and 28-isofucosterol by larix decidua leaves. 1969 Biochem. J. pmid:5348842
De Souza NJ et al. Studies on insect moulting hormones: biosynthesis of ponasterone A and ecdysterone from [2-14C] mevalonate in Taxus baccata. 1969 Biochem. J. pmid:5343810
Bolger LM et al. Incorporation of [2-14C] mevalonic acid into 28-isofucosterol by leaves of Pisum sativum. 1969 Biochem. J. pmid:5343809
Money T et al. Biosynthesis of the indole alkaloids. 1965 Proc. Natl. Acad. Sci. U.S.A. pmid:5222559
Ranganathan S et al. The biosynthesis of ubiquinone in isolated rat heart cells. 1979 Arch. Biochem. Biophys. pmid:518096
Goldfarb S and Pitot HC Improved assay of 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1971 J. Lipid Res. pmid:5164097
pmid:5160408
Baisted DJ Sterol and triterpene synthesis in the developing and germinating pea seed. 1971 Biochem. J. pmid:5158507
Ogura M et al. Studies on the cholesterol pool as the precursor of bile acids in the rat. 1971 J. Biochem. pmid:5144357
Chida N and Okamura T Increased cholesterol-biosynthesis in familial hypercholesterolemia. 1971 Tohoku J. Exp. Med. pmid:5140375
pmid:5135515
Yamasaki K et al. Isolation of 3 7 -dihydroxychol-5-en-24-oic acid, an intermediate of chenodeoxycholic acid biogenesis, from fistula bile of the rat and hen. 1971 J. Biochem. pmid:5134665
Díaz Zagoya JC et al. Studies on the regulation of cholesterol metabolism by the use of the structural analogue, diosgenin. 1971 Biochem. Pharmacol. pmid:5132893
Ramsey RB et al. Formation of methyl sterols in brain cholesterol biosynthesis. Sterol formation in vitro and in vivo in adult rat brain. 1971 J. Biol. Chem. pmid:5132663
Hornby GM and Boyd GS The origin of lanosta-7,24-dienol in rat skin. 1971 Biochem. J. pmid:5131739
Richards JB et al. Dolichol phosphates as acceptors of mannose from guanosine diphosphate mannose in liver systems. 1971 Biochem. J. pmid:5131017
Smith AG and Goad LJ Sterol biosynthesis in the starfish Asterias rubens and Henricia sanguinolenta. 1971 Biochem. J. pmid:5126917
Booth R et al. The effect of dietary cholesterol on cholesterol biosynthesis and other processes in mammalian liver. 1971 Biochem. J. pmid:5124798
Frier BM and Saudek CD Cholesterol metabolism in diabetes: the effect of insulin on the kinetics of plasma squalene. 1979 J. Clin. Endocrinol. Metab. pmid:511973
Aiyar AS et al. Biogenesis of ubiquinone in rats--an alternate origin of the benzoquinone moiety. 1971 Biochem. Biophys. Res. Commun. pmid:5117559
Hulcher FH Inhibition of hepatic cholesterol biosynthesis by 3,5-dihydroxy-3,4,4-trimethylvaleric acid and its site of action. 1971 Arch. Biochem. Biophys. pmid:5114913
Johnson DF and Daly JW Biosynthesis of cholesterol and cholesterol acetate in dendrobatid arrow poison frogs. 1971 Biochem. Pharmacol. pmid:5114496
Goodfellow RD et al. Dietary sterol effects on mevalonate kinase activity in axenic and non-axenic Sarcophaga bullata (Diptera). 1971 J. Insect Physiol. pmid:5111035
Mosbach EH et al. Bile acid synthesis in the isolated, perfused rabbit liver. 1971 J. Clin. Invest. pmid:5097576
pmid:5094244
Ramsey RB et al. The biosynthesis of cholesterol and other sterols by brain tissue. Distribution in subcellular fractions as a function of time after intracerebral injection of [2-14C]-mevalonic acid. 1971 J. Neurochem. pmid:5092868
Menkes JH Lipid metabolism in brain tissue explants. 1971 J. Neurochem. pmid:5092865
Robbers JE et al. Physiological studies on ergot: further studies on the induction of alkaloid synthesis by tryptophan and its inhibition by phosphate. 1972 J. Bacteriol. pmid:5086659
Jayaram M and Raman TS Metabolism of ergosterol in the larva of the rice moth (Corcyra cephalonica St.). 1972 Biochem. J. pmid:5085614
Rodwell VW Cholesterol regulation of hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase. 1972 Biochem. J. pmid:5085556
Goodwin TW Recent developments in the study of the biosynthesis of carotenoids. 1972 Biochem. J. pmid:5085548
Atkin SD et al. The role of cytochrome P-450 in cholesterol biogenesis and catabolism. 1972 Biochem. J. pmid:5084788
Ortiz de Montellano PR et al. Regulation of sterol biosynthesis and lysis of cultured hepatoma cells: inhibition of lanosterol demethylation by hydroxysterols. 1979 Biochem. Biophys. Res. Commun. pmid:508352
Ray PH et al. Consequences of glycerol deprivation on the synthesis of membrane components in a glycerol auxotroph of Staphylococcus aureus. 1972 J. Bacteriol. pmid:5079070
Rao GS and Ramasarma T ATP in the regulation of cholesterol biosynthesis- a supra-energetic role. 1972 Biochem. Biophys. Res. Commun. pmid:5077855
Durr IF and Habbal MZ The biosynthesis of C 55 polyprenols by a cell-free preparation of Lactobacillus plantarum. 1972 Biochem. J. pmid:5076663
Shefer S et al. Diurnal variation of HMG CoA reductase activity in rat intestine. 1972 J. Lipid Res. pmid:5075502
Gibbons GF and Mitropoulos KA Inhibition of cholesterol biosynthesis by carbon monoxide: accumulation of lanosterol and 24,25-dihydrolanosterol. 1972 Biochem. J. pmid:5073750
Barr RM and Hemming FW Polyprenol phosphate as an acceptor of mannose from guanosine diphosphate mannose in Aspergillus niger. 1972 Biochem. J. pmid:5073732
Barr RM and Hemming FW Polyprenols of Aspergillus niger. Their characterization, biosynthesis and subcellular distribution. 1972 Biochem. J. pmid:5073731
Beg ZH and Lupien PJ In vitro and in vivo inhibition of hepatic cholesterol synthesis by 3-hydroxy-3-methylglutaric acid. 1972 Biochim. Biophys. Acta pmid:5061662
Lefevre AF et al. Effect of ethanol on cholesterol and bile acid metabolism. 1972 J. Lipid Res. pmid:5059198
Hickman PE et al. Effect of adrenalectomy on the diurnal variation of hepatic cholesterogenesis in the rat. 1972 J. Lipid Res. pmid:5059193
McNamara DJ et al. Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase. Developmental pattern. 1972 J. Biol. Chem. pmid:5057084
Craig MC et al. Comparative effects of dietary regimens on the levels of enzymes regulating the synthesis of fatty acids and cholesterol in rat liver. 1972 Arch. Biochem. Biophys. pmid:5044513
Avigan J et al. In vitro biosynthesis of lipids, proteins and deoxyribonucleic acid in aortic tissue and in culture aortic cells. 1972 Biochim. Biophys. Acta pmid:5041430
Ramsey RB et al. Formation of methyl sterols in brain cholesterol biosynthesis. Sterol formation in vitro in actively myelinating rat brain. 1972 J. Biol. Chem. pmid:5030627
Ramsey RB et al. The biosynthesis of cholesterol and other sterols by brain tissue. Distribution in subcellular fractions as a function of time after intracerebral injection of (2- 14 C)mevalonic acid into 30-day-old rat brain: a period of transition. 1972 J. Neurochem. pmid:5019590
Hardman R and Fazli FR Labelled steroidal sapogenins and hydrocarbons from Trigonella foenumgraecum by acetate, mevalonate and cholesterol feeds to seeds. 1972 Planta Med. pmid:5018497
Ayaki Y and Yamasaki Identification of 3 , 7 -dihydroxychol-5-enoic acid in fistula bile of the rat given cholesterol-4- 14 C and DL-mevalonate-2- 14 C. 1972 J. Biochem. pmid:5015370
Rose HG Origin of cholesteryl esters in the blood of cholesterolfed rabbits: relative contributions of serum lecithin-cholesterol acyltransferase and hepatic ester synthesis. 1972 Biochim. Biophys. Acta pmid:5012982
Kandutsch AA and Saucier SE Sterol and fatty acid synthesis in developing brains of three myelin-deficient mouse mutants. 1972 Biochim. Biophys. Acta pmid:5012453
Streuli RA et al. Inhibition of human lymphocyte E-rosette formation by oxygenated sterols. 1979 J. Immunol. pmid:501096
Ramsey RB et al. The biosynthesis of cholesterol and other sterols by brain tissue. Distribution in subcellular fractions as a function of time after intracerebral injection into developing brain of (2- 14 C)mevalonic. 1972 J. Neurochem. pmid:5009889
Thorne KJ and Barker DC The bactoprenol content of plasma and mesosome membranes from Lactobacillus casei. 1971 Biochem. J. pmid:5001951
Lofland HB et al. Atherosclerosis in Cebus monkeys. II. Arterial metabolism. 1968 Exp. Mol. Pathol. pmid:4969998
Dietschy JM The role of bile salts in controlling the rate of intestinal cholesterogenesis. 1968 J. Clin. Invest. pmid:4966200
pmid:4920874
Marshall JD and Heiniger HJ High affinity Concanavalin A binding to sterol-depleted L cells. 1979 J. Cell. Physiol. pmid:489673
Ness GC et al. Stimulation of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity in allylamine-fed rats. 1974 Mar-Apr Atherosclerosis pmid:4855897
Heller RA and Gould RG Reversible cold inactivation of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase from rat liver. 1974 J. Biol. Chem. pmid:4854147
pmid:4852485
Gonzalez R et al. Two major regulatory steps in cholesterol synthesis by human renal cancer cells. 1979 Arch. Biochem. Biophys. pmid:485166
Kuramoto T et al. Studies on the conversion of mevalonate into bile acids and bile alcohols in toad and the stereospecific hydroxylation at carbon atom 26 during bile alcohol biogenesis. 1974 J. Biochem. pmid:4847218
Gonzalez R et al. Studies of sterol synthesis, synthesis regulation and transport in cultured human kidney. 1974 Exp. Cell Res. pmid:4841900
Phillips GT and Ross FP Stereochemistry of C-1,2-dehydrogenation during cholesterol degradation by Mycobacterium phlei. 1974 Eur. J. Biochem. pmid:4838683
Sérougne C and Chevallier F Microscopic radioautography of adult rat brain cholesterol. Problem of the blood-brain barrier. 1974 Exp. Neurol. pmid:4834203
Mayberry WR et al. Heptose-containing pentaglycosyl diglyceride among the lipids of Acholeplasma modicum. 1974 J. Bacteriol. pmid:4829931
Edwards PA and Gould RG Dependence of the circadian rhythm of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A on ribonucleic acid synthesis. A possible second site of inhibition by dietary cholesterol. 1974 J. Biol. Chem. pmid:4828326
Tint GS and Salen G Transformation of 5 alpha-cholest-7-en-3 beta-ol to cholesterol and cholestanol in cerebrotendinous xanthomatosis. 1974 J. Lipid Res. pmid:4827915
Barter PJ Production of plasma esterified cholesterol in lean, normotriglyceridemic humans. 1974 J. Lipid Res. pmid:4827913
Sodhi HS and Kudchodkar BJ A physiological method for labelling plasma lipoproteins with radioactive cholesterol. 1974 Clin. Chim. Acta pmid:4826522
Martin HG and Thorne KJ Synthesis of radioactive dolichol from (4S-3H)mevalonate in the regenerating rat liver. 1974 Biochem. J. pmid:4822733
Takashima K et al. Effect of eritadenine on cholesterol metabolism in the rat. 1974 Biochem. Pharmacol. pmid:4813355
Nicolau G et al. Determination of hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity in man. 1974 J. Lipid Res. pmid:4811219
Taddeini L et al. Acceleration of hepatic sterol synthesis after a single dose of the porphyrogenic chemical allylisopropylacetamide. 1974 J. Lipid Res. pmid:4811218
Raskin P and Siperstein MD Mevalonate metabolism by renal tissue in vitro. 1974 J. Lipid Res. pmid:4811213
Edmond J Ketone bodies as precursors of sterols and fatty acids in the developing rat. 1974 J. Biol. Chem. pmid:4809632
Edmond J and Popják G Transfer of carbon atoms from mevalonate to n-fatty acids. 1974 J. Biol. Chem. pmid:4809631
Merry AH et al. Oestrogen-stimulated cholesterol and lipid synthesis in Xenopus laevis liver. 1973 Biochem. Soc. Trans. pmid:4802550
Kandutsch AA and Chen HW Inhibition of sterol synthesis in cultured mouse cells by 7alpha-hydroxycholesterol, 7beta-hydroxycholesterol, and 7-ketocholesterol. 1973 J. Biol. Chem. pmid:4797016
Moshier SE and Chapman DJ Biosynthetic studies on aromatic carotenoids. Biosynthesis of chlorobactene. 1973 Biochem. J. pmid:4774401
Thorne KJ Incorporation of radioactive mevalonate into C50 and C55 phenols by Streptococcus mutans. 1973 Biochem. J. pmid:4772282
McDermott JC et al. Carotenoid biosynthesis in a Flavobacterium sp.: stereochemistry of hydrogen elimination in the desaturation of phytoene to lycopene, rubixanthin and zeaxanthin. 1973 Biochem. J. pmid:4762756
Collignon-Thiennot F et al. [Demonstration of 2 pathways for cholesterol synthesis in the mollusk: patella Patella vulgata L., (Gasteropoda, Prosobranches, Archeogasteropoda)]. 1973 Biochimie pmid:4754188
Ranganathan S and Ramasarma T Inhibition of the biosynthesis of sterols by phenyl and phenolic compounds in rat liver. 1973 Biochem. J. pmid:4749274
Goodwin CD and Margolis S Specific activation of in vitro cholesterol biosynthesis by preincubation of rat liver homogenates. 1973 J. Biol. Chem. pmid:4745786
Thorne KJ Identification of prenol intermediates of wall biosynthesis in growing cells of Lactobacillus plantarum. 1973 J. Bacteriol. pmid:4745415
Sérougne-Gautheron C and Chevallier F Time course of biosynthetic cholesterol in the adult rat brain. 1973 Biochim. Biophys. Acta pmid:4741912
Gibbons GF and Mitropoulos KA The effect of carbon monoxide on the nature of the accumulated 4,4-dimethyl sterol precursors of cholesterol during its biosynthesis from (2-14C)mevalonic acid in vitro. 1973 Biochem. J. pmid:4724584
Gray JC and Kekwick RG Mevalonate kinase in green leaves and etiolated cotyledons of the french bean Phaseolus vulgaris. 1973 Biochem. J. pmid:4723778
Bassett RA et al. Biosynthesis of ergotamine by Claviceps purpurea (Fr.) Tul. 1973 Biochem. J. pmid:4723222
Bojesen I and Roepstorff P Identification of C sterols produced by rat renal inner medulla in vitro. 1973 Biochim. Biophys. Acta pmid:4722467