Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Leukemia D007938 74 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Nishimura M et al. Collagen secretion and growth of mesangial cells require geranylgeranylpyrophosphate. 1999 Kidney Int. pmid:9987076
pmid:9920100
pmid:990276
pmid:9882513
Fisher JE et al. Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:9874784
pmid:9872842
Petras SF et al. HMG-CoA reductase regulation: use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator production in cultured IM-9 cells. 1999 J. Lipid Res. pmid:9869647
Holleran AL et al. Effect of tamoxifen on cholesterol synthesis in HepG2 cells and cultured rat hepatocytes. 1998 Metab. Clin. Exp. pmid:9867082
Melichar B et al. Growth inhibitory effects of aromatic fatty acids on ovarian tumor cell lines. 1998 Clin. Cancer Res. pmid:9865922
Wellburn AR and Hampp R Uptake of mevalonate and acetate during plastid development. 1976 Biochem. J. pmid:985424
Shipman CM et al. The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway. 1998 Cancer Res. pmid:9850051
Disch A and Rohmer M On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts. 1998 FEMS Microbiol. Lett. pmid:9835029
Lamb DC et al. A sterol biosynthetic pathway in Mycobacterium. 1998 FEBS Lett. pmid:9804188
Schedin S et al. Alterations in the biosynthesis of cholesterol, dolichol and dolichyl-P in the genetic cholesterol homeostasis disorder, Niemann-Pick type C disease. 1998 Biochim. Biophys. Acta pmid:9795206
Naoumova RP et al. Cholesterol synthesis is increased in mixed hyperlipidaemia. 1998 Biochim. Biophys. Acta pmid:9795192
Michikawa M and Yanagisawa K Apolipoprotein E4 induces neuronal cell death under conditions of suppressed de novo cholesterol synthesis. 1998 J. Neurosci. Res. pmid:9778150
Ogura M et al. Further studies on the possible compartmentation of the precursor pool of cholesterol for the biosynthesis of cholic acid in the rat. 1976 J. Biochem. pmid:977552
Coxon FP et al. Protein synthesis is required for caspase activation and induction of apoptosis by bisphosphonate drugs. 1998 Mol. Pharmacol. pmid:9765505
Hiramatsu M et al. Enzyme immunoassay of urinary mevalonic acid and its clinical application. 1998 Clin. Chem. pmid:9761249
Aboushadi N and Krisans SK Analysis of isoprenoid biosynthesis in peroxisomal-deficient Pex2 CHO cell lines. 1998 J. Lipid Res. pmid:9741690