Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Biliary Fistula D001658 13 associated lipids
Body Weight D001835 333 associated lipids
Celiac Disease D002446 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Kandoussi A et al. HMG-CoA reductase inhibition and PPAR- alpha activation both inhibit cyclosporin A induced endothelin-1 secretion in cultured endothelial cells. 2002 Clin. Sci. pmid:12193060
Fahien LA and MacDonald MJ The succinate mechanism of insulin release. 2002 Diabetes pmid:12196457
Miyazaki A et al. Effects of pravastatin sodium on mevalonate metabolism in common marmosets. 2002 J. Biochem. pmid:12204108
pmid:12208479
Kasahara H et al. Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of gibberellins in Arabidopsis. 2002 J. Biol. Chem. pmid:12228237
Amin R et al. Inhibition of glucose- and calcium-induced insulin secretion from betaTC3 cells by novel inhibitors of protein isoprenylation. 2002 J. Pharmacol. Exp. Ther. pmid:12235236
Miyashita Y et al. Oxysterol-induced apoptosis of vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitor, pravastatin. 2002 J. Atheroscler. Thromb. pmid:12238640
pmid:12352324
Kuzuyama T Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units. 2002 Biosci. Biotechnol. Biochem. pmid:12353619
Pappu AS et al. Feedback inhibition of the cholesterol biosynthetic pathway in patients with Smith-Lemli-Opitz syndrome as demonstrated by urinary mevalonate excretion. 2002 J. Lipid Res. pmid:12364550
Hümbelin M et al. Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens. 2002 Gene pmid:12384294
Stamatakis K et al. Isoprenylation of RhoB is necessary for its degradation. A novel determinant in the complex regulation of RhoB expression by the mevalonate pathway. 2002 J. Biol. Chem. pmid:12384510
Frenkel J et al. Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome. 2002 Arthritis Rheum. pmid:12384940
Mason JC et al. Statin-induced expression of decay-accelerating factor protects vascular endothelium against complement-mediated injury. 2002 Circ. Res. pmid:12386146
Carnesecchi S et al. Perturbation by geraniol of cell membrane permeability and signal transduction pathways in human colon cancer cells. 2002 J. Pharmacol. Exp. Ther. pmid:12388655
Nishikimi T et al. Cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, inhibits cardiac myocyte hypertrophy induced by endothelin. 2002 Eur. J. Pharmacol. pmid:12398901
Ropero S et al. Cholesterol cell content modulates GTPase activity of G proteins in GH4C1 cell membranes. 2003 Cell. Signal. pmid:12401528
Parhami F et al. Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells. 2002 J. Bone Miner. Res. pmid:12412807
Wagner AH et al. 3-hydroxy-3-methylglutaryl coenzyme A reductase-independent inhibition of CD40 expression by atorvastatin in human endothelial cells. 2002 Arterioscler. Thromb. Vasc. Biol. pmid:12426205
Holstein SA et al. Isoprenoids influence expression of Ras and Ras-related proteins. 2002 Biochemistry pmid:12427032
Rodríguez-Concepción M and Boronat A Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics. 2002 Plant Physiol. pmid:12427975
Wang W et al. Cerivastatin enhances the cytotoxicity of 5-fluorouracil on chemosensitive and resistant colorectal cancer cell lines. 2002 FEBS Lett. pmid:12435585
pmid:12444096
Martin PD et al. Pharmacodynamic effects and pharmacokinetics of a new HMG-CoA reductase inhibitor, rosuvastatin, after morning or evening administration in healthy volunteers. 2002 Br J Clin Pharmacol pmid:12445025
Nagata N et al. Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway. 2002 Planta pmid:12447549
Phillips GT and Clifford KH Stereochemistry of a methyl-group rearrangement during the biosynthesis of lanosterol. 1976 Eur. J. Biochem. pmid:1245185
Arkwright PD et al. Hyper IgD syndrome (HIDS) associated with in vitro evidence of defective monocyte TNFRSF1A shedding and partial response to TNF receptor blockade with etanercept. 2002 Clin. Exp. Immunol. pmid:12452839
pmid:12467639
Naidu A et al. Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins. 2002 Brain Res. pmid:12468034
Choi M et al. Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA. 2003 Kidney Int. pmid:12472772
Alla S et al. [Mevalonolactone: a volatile compound produced by Psammotettix alienus (Dhb)]. 2002 C. R. Biol. pmid:12481687
pmid:12492458
pmid:12499535
pmid:12503192
pmid:12504097
pmid:12509999
Kalinowski L et al. Cerivastatin potentiates nitric oxide release and enos expression through inhibition of isoprenoids synthesis. 2002 J. Physiol. Pharmacol. pmid:12512694
Flores-Sánchez IJ et al. Biosynthesis of sterols and triterpenes in cell suspension cultures of Uncaria tomentosa. 2002 Plant Cell Physiol. pmid:12514247
Miyazawa Y et al. Amyloplast formation in cultured tobacco BY-2 cells requires a high cytokinin content. 2002 Plant Cell Physiol. pmid:12514251
Peffley DM and Gayen AK Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme a reductase synthesis at the post-transcriptional level. 2003 J. Nutr. pmid:12514264
Kreck M et al. Biogenetic studies in Syringa vulgaris L.: synthesis and bioconversion of deuterium-labeled precursors into lilac aldehydes and lilac alcohols. 2003 J. Agric. Food Chem. pmid:12517111
Wiss O Influence of a lipogenic diet on the cholesterol synthesis in rats in vivo. 1976 Biochem. Biophys. Res. Commun. pmid:1252232
Kuzuyama T et al. Detection of the mevalonate pathway in Streptomyces species using the 3-hydroxy-3-methylglutaryl coenzyme A reductase gene. 2002 J. Antibiot. pmid:12523826
pmid:12525568
pmid:12528472
Shimada Y et al. Organ-specific expression of brassinosteroid-biosynthetic genes and distribution of endogenous brassinosteroids in Arabidopsis. 2003 Plant Physiol. pmid:12529536
Sever N et al. Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain. 2003 Mol. Cell pmid:12535518
Gober HJ et al. Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells. 2003 J. Exp. Med. pmid:12538656
pmid:12543573
pmid:12563048