Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Biliary Fistula D001658 13 associated lipids
Body Weight D001835 333 associated lipids
Celiac Disease D002446 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

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All references with Mevalonic acid

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HONG L and WRIGHT LD Paper chromatography of mevalonate and acetate. 1957 Biochim. Biophys. Acta pmid:13479486
GOODWIN TW Studies in carotenogenesis. 25. The incorporation of 14CO2, [2-14C] acetate and [2-14C]mevalonate into beta-carotene by illuminated etiolated maize seedings. 1958 Biochem. J. pmid:13607416
PARK RB and BONNER J Enzymatic synthesis of rubber from mevalonic acid. 1958 J. Biol. Chem. pmid:13563498
DE WAARD A and POPJAK G Studies on the biosynthesis of cholesterol. 9. Formation of phosphorylated derivatives of mevalonic acid in liver-enzyme preparations. 1959 Biochem. J. pmid:13815126
WITTING LA and PORTER JW Intermediates in the conversion of mevalonic acid to squalene by a rat liver enzyme system. 1959 J. Biol. Chem. pmid:13845505
NICHOLAS HJ and THOMAS BE Intracerebral incorporation of [2-14C]mevalonic acid into adult rat brain squalene and cholesterol. 1959 Biochim. Biophys. Acta pmid:13854106
MARKLEY K and GURIN S Decarboxylation of mevalonic acid and conversion to squalene; enzyme fractionation and cofactors. 1959 Biochim. Biophys. Acta pmid:13628647
RILLING HC and BLOCH K On the mechanism of squaiene biogenesis from mevalonic acid. 1959 J. Biol. Chem. pmid:13654391
GOSSELIN L and POPJAK G Studies on biosynthesis of cholesterol. 8. The effect of Mg2+ and Mn2+ ions and of adenosine triphosphate on enzymic activity of microsomes in sterol biosynthesis from mevalonic acid. 1959 Biochem. J. pmid:13651113
GARATTINI S et al. Lipid biosynthesis in vivo from acetate-1-C 14 and 2-C 14 and mevalonic-2-C 14 acid. 1959 Arch. Biochem. Biophys. pmid:13826357
KNAUSS HJ et al. The biosynthesis of mevalonic acid from 1-C14-acetate by a rat liver enzyme system. 1959 J. Biol. Chem. pmid:14410081
BLOCH K et al. Mevalonic acid pyrophosphate and isopentenylpyrophosphate. 1959 J. Biol. Chem. pmid:13801508
PURCELL AE et al. The incorporation of mevalonic acid into tomato carotenoids. 1959 J. Biol. Chem. pmid:13654323
DURR IF and RUDNEY H The reduction of beta-hydroxy-beta-methyl-glutaryl coenzyme A to mevalonic acid. 1960 J. Biol. Chem. pmid:13818862
BRAITHWAITE GD and GOODWIN TW Studies in carotenogenesis. 27. Incorporation of [2-14C] acetate, DL-[2-14C] mevalonate and C14-labelled carbon dioxide into carrotroot preparations. 1960 Biochem. J. pmid:13849153
BRAITHWAITE GD and GOODWIN TW Studies in carotenogenesis. 26. The incorporation of [C14] acetate, [C14] mevalonate and C14-labelled carbon dioxide into beta-carotene by the fungus Phycomyces blakesleeanus. 1960 Biochem. J. pmid:13849152
ELWOOD JC et al. Lipid metabolism in the diabetic rat. IV. Metabolism of acetate, acetoacetate, butyrate, and mevalonate in vitro. 1960 J. Biol. Chem. pmid:13820133
POPJAK G et al. Studies on the biosynthesis of cholesterol. XV. Mechanism of squalene biosynthesis from farnesyl pyrophosphate and from mevalonate. 1961 J. Biol. Chem. pmid:13737104
SHAH SN et al. The effect of growth hormone administration and dietary protein on the incorporation of sodium acetate-2-C14 and mevalonic acid-2-C14 into liver cholesterol. 1961 Arch. Biochem. Biophys. pmid:13750592
RAMASARMA T and RAMAKRISHNAN T Incorporation of [2-14C]mevalonic acid and [2-14C]acetic acid into lipids of mycobacteria. 1961 Biochem. J. pmid:14038591
SCHLESINGER MJ and COON MJ Reduction of mevaldic acid to mevalonic acid by a partially purified enzyme from liver. 1961 J. Biol. Chem. pmid:13747804
TADA M and LYNEN F [On the biosynthesis of terpenes. XIV. On the determination of phosphomevalonic acid kinase and pyrophosphomevalonic acid decarboxylase in cell extracts]. 1961 J. Biochem. pmid:13774769
FUMAGALLI R et al. Cholesterol synthesis in rat brain: differential incorporation of mevalonolactone-2-C14 and potassium mevalonate-2-C14. 1962 Arch. Biochem. Biophys. pmid:13960261
OHNOKI D et al. D5-Phosphomevalonic acid as the intermediate of the enzymatic synthesis of bacterial phytoene. 1962 J. Biochem. pmid:13939688
NICHOLAS HJ Biosynthesis of sclareol, beta-sitosterol, and oleanolic acid from mevalonic acid-2-C-14. 1962 J. Biol. Chem. pmid:14479433
GOODMAN DS et al. Studies of cholesterol biosynthesis. V. The time course and pathway of the later stages of cholesterol biosynthesis in the livers of intact rats. 1963 J. Biol. Chem. pmid:13949089
DALY MM et al. CHOLESTEROL CONCENTRATION AND CHOLESTEROL SYNTHESIS IN AORTAS OF RATS WITH RENAL HYPERTENSION. 1963 J. Clin. Invest. pmid:14074354
PORTMAN OW and SUGANO M THE HYDROLYSIS AND FATTY ACID EXCHANGE OF CHOLESTEROL ESTERS ADMINISTERED IN LIPOPROTEINS TO CEBUS MONKEYS. 1963 Arch. Biochem. Biophys. pmid:14072510
GAYLOR JL Biosynthesis of skin sterols. V. Effect of arsenite inhibition and the accumulation of labeled lanosta-7, 24-dien-3 beta-ol in rat skin. 1963 Arch. Biochem. Biophys. pmid:13946925
BEELER DA et al. The biosynthesis of squalene from mevalonic acid-2-C-14 and farnesyl pyrophosphate-4,8,12-C-14 by carrot and tomato enzymes. 1963 Arch. Biochem. Biophys. pmid:13970235
BEHER WT et al. TIME COURSE OF FECAL STEROID-C14 EXCRETION IN VARIOUS RODENTS. 1963 Am. J. Physiol. pmid:14084977
TERNER C and KORSH G THE BIOSYNTHESIS OF GLYCERIDES IN HOMOGENATES OF NORMAL LACTATING MAMMARY GLAND AND OF MAMMARY TUMOR TISSUE OF THE MOUSE. 1963 Cancer Res. pmid:14079150
BRODIE JD et al. The participation of malonyl coenzyme A in the biosynthesis of mevalonic acid. 1963 J. Biol. Chem. pmid:14015675
Malathi P and Ganguly J Studies on metabolism of vitamin A. 8. Effect of ascorbate on isoprenoid metabolism in vitamin A-deficient rats. 1964 Biochem. J. pmid:5837438
TSAI SC et al. TESTICULAR STEROLS. 1. INCORPORATION OF MEVALONATE AND ACETATE INTO STEROLS BY TESTICULAR TISSUE FROM RATS. 1964 Arch. Biochem. Biophys. pmid:14186739
MEROLA AJ and ARNOLD A ESTRONE INHIBITION OF CHOLESTEROL BIOSYNTHESIS AT THE MEVALONIC ACID STAGE. 1964 Science pmid:14169718
BAILEY JM LIPID METABOLISM IN CULTURED CELLS. 3. CHOLESTEROL EXCRETION PROCESS. 1964 Am. J. Physiol. pmid:14251922
Caravaca J and May MD The isolation and properties of an active peroxidase from hepatocatalase. 1964 Biochem. Biophys. Res. Commun. pmid:4380864
SHEFER S et al. BIOSYNTHESIS OF 5-ALPHA-CHOLESTAN-3-BETA-OL IN THE RABBIT AND GUINEA PIG. 1964 J. Biol. Chem. pmid:14213342
DURR IF and SHWAYRI AN METABOLISM OF MEVALONIC ACID BY LACTOBACILLUS PLANTARUM. 1964 J. Bacteriol. pmid:14203352
Joshi VC et al. Biosynthetic relationship between ubichromenol and ubiquinone. 1964 Biochem. J. pmid:5838088
BRODIE JD et al. ENZYME-BOUND INTERMEDIATES IN THE BIOSYNTHESIS OF MEVALONIC AND PALMITIC AICDS. 1964 J. Biol. Chem. pmid:14189864
GOODMAN DS and SHIRATORI T IN VIVO TURNOVER OF DIFFERENT CHOLESTEROL ESTERS IN RAT LIVER AND PLASMA. 1964 J. Lipid Res. pmid:14221103
AARONSON S A ROLE FOR A STEROL AND A STEROL PRECURSOR IN THE BACTERIUM RHODOPSEUDOMONAS PALUSTRIS. 1964 J. Gen. Microbiol. pmid:14247747
GOODMAN DS THE IN VIVO TURNOVER OF INDIVIDUAL CHOLESTEROL ESTERS IN HUMAN PLASMA LIPOPROTEINS. 1964 J. Clin. Invest. pmid:14223916
SUGANO M and PORTMAN OW FATTY ACID SPECIFICITIES AND RATES OF CHOLESTEROL ESTERIFICATION IN VIVO AND IN VITRO. 1964 Arch. Biochem. Biophys. pmid:14224844
Teal SW and Gamble W Effect of p-chlorophenoxyisobutyric acid, ethyl p-chlorophenoxyisobutyrate, and Atromid on the synthesis of nonsaponifiable material and cholesterol in the bovine aorta. 1965 Biochem. Pharmacol. pmid:5840738
DIPLOCK AT et al. VITAMIN A AND ISOPRENOID SYNTHESIS IN THE RAT. 1965 Biochem. J. pmid:14333548
GOODWIN TW and WILLIAMS RJ A MECHANISM FOR THE CYCLIZATION OF AN ACYCLIC PRECURSOR TO FORM BETA-CAROTENE. 1965 Biochem. J. pmid:14342248
HELLIG HR and SAVARD K BIOSYNTHESIS OF PROGESTERONE, STEROLS, AND SQUALENE FROM ACETATE-1-14-C AND MEVALONATE-2-14-C BY THE BOVINE CORPUS LUTEUM IN VITRO. 1965 J. Biol. Chem. pmid:14299614
FIMOGNARI GM and RODWELL VW CHOLESTEROL BIOSYNTHESIS: MEVALONATE SYNTHESIS INHIBITED BY BILE SALTS. 1965 Science pmid:14245778
Stone KJ and Hemming FW The incorporation of [2-14C, 4R-3H1] mevalonate and [2-14C, 4S-3H1] mevalonate into squalene, ubiquinone and ergosterol of Aspergillus fumigatus Fresenius. 1965 Biochem. J. pmid:4284430
Niemiro R and Fumagalli R Studies on the inhibitory mechanism of some hypocholesterolemic agents on 7-dehydrocholesterol delta-7-bond reductase activity. 1965 Biochim. Biophys. Acta pmid:4284414
SHEFER S et al. BIOSYNTHESIS OF 5-ALPHA-CHOLESTAN-3-BETA-OL IN RAT AND GUINEA PIG LIVER IN VITRO. 1965 J. Lipid Res. pmid:14280469
Mitropoulos KA and Myant NB Evidence that the oxidation of the side chain of cholesterol by liver mitochondria is stereospecific, and that the immediate product of cleavage is propionate. 1965 Biochem. J. pmid:5881647
KRITCHEVSKY D et al. STUDIES ON THE BIOSYNTHESIS OF LIPIDS IN THE BABOON. BIOSYNTHESIS AND TRANSPORT OF CHOLESTEROL. 1965 Clin. Chim. Acta pmid:14287064
AZARNOFF DL et al. STUDIES WITH ETHYL CHLOROPHENOXYISOBUTYRATE (CLOFIBRATE). 1965 Metab. Clin. Exp. pmid:14327272
Hsu RY et al. The purification and properties of the fatty acid synthetase of pigeon liver. 1965 J. Biol. Chem. pmid:4378857
Williamson IP and Kekwick RG The formation of 5-phosphomevalonate by mevalonate kinase in Hevea brasiliensis latex. 1965 Biochem. J. pmid:5862423
Money T et al. Biosynthesis of the indole alkaloids. 1965 Proc. Natl. Acad. Sci. U.S.A. pmid:5222559
GRAEBE JE et al. BIOSYNTHESIS OF GIBBERELLINS. I. THE BIOSYNTHESIS OF (-)-KAUREN-19-OL, AND TRANS-GERANYLGERANIOL IN ENDOSPERM NUCELLUS OF ECHINOCYSTIS MACROCARPA GREENE. 1965 J. Biol. Chem. pmid:14289357
SMITH PF and HENRIKSON CV COMPARATIVE BIOSYNTHESIS OF MEVALONIC ACID BY MYCOPLASMA. 1965 J. Bacteriol. pmid:14255655
Goodwin TW and Williams RJ A mechanism for the biosynthesis of alpha-carotene. 1965 Biochem. J. pmid:5881648
Cornforth JW et al. Studies on the biosynthesis of cholesterol. XX. Steric course of decarboxylation of 5-pyrophosphomevalonate and of the carbon to carbon bond formation in the biosynthesis of farnesyl pyrophosphate. 1966 J. Biol. Chem. pmid:4288360
Gold PH and Olson RE Studies on coenzyme Q. The biosynthesis of coenzyme Q9 in rat tissue slices. 1966 J. Biol. Chem. pmid:5919683
Gould RG and Swyryd EA Sites of control of hepatic cholesterol biosynthesis. 1966 J. Lipid Res. pmid:5971049
Ockner RK and Laster L Biosynthesis of delta-7-cholesten-3-beta-ol, delta-5,7-cholestadien-3-beta-ol, and delta-5-cholesten-3-beta-ol by guinea pig intestinal mucosa in vitro. 1966 J. Lipid Res. pmid:5971571
Ogilvie JW and Kaplan BH The inhibition of sterol biosynthesis in rat liver homogenates by bile. 1966 J. Biol. Chem. pmid:5926178
Henrikson CV and Smith PF Conversion of mevalonic acid to gamma, gamma-dimethylallyl pyrophosphate by Mycoplasma. 1966 J. Bacteriol. pmid:4288495