Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Biliary Fistula D001658 13 associated lipids
Body Weight D001835 333 associated lipids
Celiac Disease D002446 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 | Total 25

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
pmid:
Bell FP Biosynthesis of various sterols, sterol esters, and squalene from [14C]mevalonate by normal swine intima and media in vitro: a comparative study. 1976 Exp. Mol. Pathol. pmid:1001402
Yoshida T et al. Plasma levels of mevalonate and 7alpha-hydroxy-4-cholesten-3-one in chronic liver disease. 1999 J. Gastroenterol. Hepatol. pmid:10029296
Mutoh T et al. Involvement of tyrosine phosphorylation in HMG-CoA reductase inhibitor-induced cell death in L6 myoblasts. 1999 FEBS Lett. pmid:10037153
Vion-Dury J et al. Atlas of brain proton magnetic resonance spectra. Part II: Inherited metabolic encephalopathies. 1998 J Neuroradiol pmid:10048272
Bassa BV et al. Effect of inhibition of cholesterol synthetic pathway on the activation of Ras and MAP kinase in mesangial cells. 1999 Biochim. Biophys. Acta pmid:10082972
Choi JW and Jung SE Lovastatin-induced proliferation inhibition and apoptosis in C6 glial cells. 1999 J. Pharmacol. Exp. Ther. pmid:10087052
Parmryd I and Dallner G In vivo prenylation of rat proteins: modification of proteins with penta- and hexaprenyl groups. 1999 Arch. Biochem. Biophys. pmid:10190969
Niku-Paavola ML et al. New types of antimicrobial compounds produced by Lactobacillus plantarum. 1999 J. Appl. Microbiol. pmid:10200070
pmid:10216221
van beek E et al. The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates. 1999 J. Bone Miner. Res. pmid:10320520
pmid:10333388
Michikawa M and Yanagisawa K Inhibition of cholesterol production but not of nonsterol isoprenoid products induces neuronal cell death. 1999 J. Neurochem. pmid:10349836
Naoumova RP et al. Effect of inhibiting HMG-CoA reductase on 7 alpha-hydroxy-4-cholesten-3-one, a marker of bile acid synthesis: contrasting findings in patients with and without prior up-regulation of the latter pathway. 1999 Eur. J. Clin. Invest. pmid:10354197
Cenedella RJ et al. Lens epithelia contain a high-affinity, membrane steroid hormone-binding protein. 1999 Invest. Ophthalmol. Vis. Sci. pmid:10359327
Kikuchi A et al. Evidence for covalent attachment of diphytanylglyceryl phosphate to the cell-surface glycoprotein of Halobacterium halobium. 1999 J. Biol. Chem. pmid:10364251
pmid:10369261
Girgert R et al. Growth inhibition of neuroblastoma cells by lovastatin and L-ascorbic acid is based on different mechanisms. 1999 Cancer Lett. pmid:10374838
Rao S et al. Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10393901
Bifulco M et al. Inhibition of farnesylation blocks growth but not differentiation in FRTL-5 thyroid cells. 1999 Biochimie pmid:10401660
Rha SY et al. Modulation of biological phenotypes for tumor growth and metastasis by target-specific biological inhibitors in gastric cancer. 1999 Int. J. Mol. Med. pmid:10402490
pmid:10413074
Laufs U et al. 3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1). 1999 J. Biol. Chem. pmid:10419514
pmid:10423031
Ghosh PM et al. Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. 1999 Oncogene pmid:10435593
Vega GL et al. Effect of lifibrol on the metabolism of low density lipoproteins and cholesterol. 1999 J. Intern. Med. pmid:10447220
Bacurau RF et al. Metabolic response of macrophages to injury promoted by the activated complement system. 1999 Cell Biochem. Funct. pmid:10451538
Ginger ML et al. Elucidation of carbon sources used for the biosynthesis of fatty acids and sterols in the trypanosomatid Leishmania mexicana. 1999 Biochem. J. pmid:10455027
Sato R et al. Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription. 1999 J. Biol. Chem. pmid:10455139
pmid:10460692
Parmryd I et al. Protein prenylation in spinach chloroplasts. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10468564
Appelkvist EL et al. Synthesis of mevalonate pathway lipids in fibroblasts from Zellweger and X-linked ALD patients. 1999 Pediatr. Res. pmid:10473053
Agarwal B et al. Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells. 1999 Clin. Cancer Res. pmid:10473109
Jomaa H et al. Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. 1999 Science pmid:10477522
Koch T et al. Differential induction of plant volatile biosynthesis in the lima bean by early and late intermediates of the octadecanoid-signaling pathway. 1999 Plant Physiol. pmid:10482670
Ravid T et al. Impaired regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation in lovastatin-resistant cells. 1999 J. Biol. Chem. pmid:10506194
pmid:10527548
pmid:10527849
Gardner RG and Hampton RY A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes. 1999 J. Biol. Chem. pmid:10531376
Giordano W et al. Lovastatin inhibits the production of gibberellins but not sterol or carotenoid biosynthesis in Gibberella fujikuroi. 1999 Microbiology (Reading, Engl.) pmid:10537222
Shack S et al. Activation of the cholesterol pathway and Ras maturation in response to stress. 1999 Oncogene pmid:10557091
Kaul D and Kaur M Receptor-Ck regulates the expression of cyclin-dependent kinase inhibitors (p16; p27). 1999 Mol. Cell. Biochem. pmid:10569199
Lange BM and Croteau R Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10570138
Reszka AA et al. Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosis-promoting kinase. 1999 J. Biol. Chem. pmid:10574973
pmid:10591153
Kim DY et al. Expression and characterization of the HMG-CoA reductase of the thermophilic archaeon Sulfolobus solfataricus. 1999 Protein Expr. Purif. pmid:10600463
Keller RK and Fliesler SJ Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway. 1999 Biochem. Biophys. Res. Commun. pmid:10600541
Liu GC et al. Measurement of cholesterol synthesis in man by isotope kinetics of squalene. 1975 Proc. Natl. Acad. Sci. U.S.A. pmid:1060141
Elkin RG and Yan Z Relationship between inhibition of mevalonate biosynthesis and reduced fertility in laying hens. 1999 J. Reprod. Fertil. pmid:10615252
Kim SI et al. Lovastatin inhibits transforming growth factor-beta1 expression in diabetic rat glomeruli and cultured rat mesangial cells. 2000 J. Am. Soc. Nephrol. pmid:10616843