| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hypergammaglobulinemia | D006942 | 9 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Peutz-Jeghers Syndrome | D010580 | 2 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Li Z et al. | Effect of temperature on postillumination isoprene emission in oak and poplar. | 2011 | Plant Physiol. | pmid:21177471 |
| Yu F et al. | Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis. | 2011 | Cell. Mol. Life Sci. | pmid:20730551 |
| Youn YN et al. | Impact of High-Dose Statin Pretreatment in Patients with Stable Angina during Off-Pump Coronary Artery Bypass. | 2011 | Korean J Thorac Cardiovasc Surg | pmid:22263153 |
| Odom AR | Five questions about non-mevalonate isoprenoid biosynthesis. | 2011 | PLoS Pathog. | pmid:22216001 |
| Rauthan M and Pilon M | The mevalonate pathway in C. elegans. | 2011 | Lipids Health Dis | pmid:22204706 |
| Barrero RA et al. | De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes. | 2011 | BMC Genomics | pmid:22151917 |
| Leszczynska A et al. | Different statins produce highly divergent changes in gene expression profiles of human hepatoma cells: a pilot study. | 2011 | Acta Biochim. Pol. | pmid:22132374 |
| Ramgolam VS and Markovic-Plese S | Regulation of suppressors of cytokine signaling as a therapeutic approach in autoimmune diseases, with an emphasis on multiple sclerosis. | 2011 | J Signal Transduct | pmid:22132325 |
| Cho SH et al. | Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller. | 2011 | Nutr Res Pract | pmid:22125678 |
| Tijerino A et al. | Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings. | 2011 | Toxins (Basel) | pmid:22069764 |
| Wang H et al. | Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism. | 2011 | J. Immunol. | pmid:22013129 |
| Ali OF et al. | Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. | 2011 | Respir. Res. | pmid:21999923 |
| Cheng G et al. | Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. | 2011 | Cancer Biol. Ther. | pmid:21799303 |
| Katuru R et al. | Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. | 2011 | Exp. Biol. Med. (Maywood) | pmid:21540247 |
| Peng LF et al. | Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. | 2011 | J. Infect. Dis. | pmid:21791663 |
| Bajgain P et al. | Transcriptome characterization and polymorphism detection between subspecies of big sagebrush (Artemisia tridentata). | 2011 | BMC Genomics | pmid:21767398 |
| Scheller EL et al. | Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production. | 2011 | J. Cell. Biochem. | pmid:21751240 |
| Sun S and McKenna CE | Farnesyl pyrophosphate synthase modulators: a patent review (2006 - 2010). | 2011 | Expert Opin Ther Pat | pmid:21702715 |
| Rizzo WB | The role of fatty aldehyde dehydrogenase in epidermal structure and function. | 2011 | Dermatoendocrinol | pmid:21695018 |
| Waldron J and Webster C | Liquid chromatography-tandem mass spectrometry method for the measurement of serum mevalonic acid: a novel marker of hydroxymethylglutaryl coenzyme A reductase inhibition by statins. | 2011 | Ann. Clin. Biochem. | pmid:21355014 |
| Tsang A et al. | Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulation. | 2011 | PLoS ONE | pmid:21694781 |
| Rossoni LV et al. | Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries. | 2011 | Clin. Sci. | pmid:21671887 |
| Maekawa T et al. | Chronic oral infection with Porphyromonas gingivalis accelerates atheroma formation by shifting the lipid profile. | 2011 | PLoS ONE | pmid:21625524 |
| Jeon JG et al. | Natural products in caries research: current (limited) knowledge, challenges and future perspective. | 2011 | Caries Res. | pmid:21576957 |
| Scheller EL et al. | Bisphosphonates inhibit expression of p63 by oral keratinocytes. | 2011 | J. Dent. Res. | pmid:21551338 |
| Kishi T | Mevalonate pathway is a novel target for hypertension. | 2011 | Circ. J. | pmid:21532185 |
| Sivy TL et al. | Evidence of isoprenoid precursor toxicity in Bacillus subtilis. | 2011 | Biosci. Biotechnol. Biochem. | pmid:22146731 |
| Song JX et al. | Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway. | 2011 | J. Cardiovasc. Pharmacol. | pmid:21052011 |
| Soliman SS et al. | Chemical inhibitors suggest endophytic fungal paclitaxel is derived from both mevalonate and non-mevalonate-like pathways. | 2011 | J. Nat. Prod. | pmid:22103292 |
| Ignea C et al. | Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. | 2011 | Microb. Cell Fact. | pmid:21276210 |
| Tuckow AP et al. | Simvastatin represses protein synthesis in the muscle-derived Câ‚‚Câ‚â‚‚ cell line with a concomitant reduction in eukaryotic initiation factor 2B expression. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:21224482 |
| Tsubaki M et al. | Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma. | 2011 | Cytokine | pmid:21292498 |
| Sawai S and Saito K | Triterpenoid biosynthesis and engineering in plants. | 2011 | Front Plant Sci | pmid:22639586 |
| Kim KH et al. | Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants. | 2011 | Drug Metab. Dispos. | pmid:20962060 |
| Miziorko HM | Enzymes of the mevalonate pathway of isoprenoid biosynthesis. | 2011 | Arch. Biochem. Biophys. | pmid:20932952 |
| Hong C et al. | Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target. | 2011 | J. Lipid Res. | pmid:21187453 |
| Nishikawa Y et al. | Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages. | 2011 | J. Vet. Med. Sci. | pmid:21187676 |
| Tsuyuki R et al. | Enhancement of trichothecene production in Fusarium graminearum by cobalt chloride. | 2011 | J. Agric. Food Chem. | pmid:21299216 |
| Li YY et al. | Zoledronic acid induces cell-cycle prolongation in murine lung cancer cells by perturbing cyclin and Ras expression. | 2011 | Anticancer Drugs | pmid:20926944 |
| Nilsson S et al. | Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells. | 2011 | Cancer Lett. | pmid:21356574 |
| Murtola TJ et al. | Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL. | 2011 | Eur. J. Pharmacol. | pmid:22040920 |
| Sakai H and Heike T | [Hyperimmunoglobulinemia D and periodic fever syndrome]. | 2011 | Nihon Rinsho Meneki Gakkai Kaishi | pmid:22041426 |
| Issat T et al. | Antitumor effects of the combination of cholesterol reducing drugs. | 2011 | Oncol. Rep. | pmid:21491092 |
| Varman AM et al. | Statistics-based model for prediction of chemical biosynthesis yield from Saccharomyces cerevisiae. | 2011 | Microb. Cell Fact. | pmid:21689458 |
| Goto T et al. | Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. | 2011 | Biochem. J. | pmid:21605082 |
| Clastre M et al. | Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. | 2011 | Plant Signal Behav | pmid:22080790 |
| Castella B et al. | Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells. | 2011 | J. Immunol. | pmid:21753152 |
| Okada K | The biosynthesis of isoprenoids and the mechanisms regulating it in plants. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21737944 |
| Kim YS et al. | Increase of lycopene production by supplementing auxiliary carbon sources in metabolically engineered Escherichia coli. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21246354 |
| Duke SO and Dayan FE | Modes of action of microbially-produced phytotoxins. | 2011 | Toxins (Basel) | pmid:22069756 |
| Kindt E et al. | The validation of a simple LC/MS/MS method for determining the level of mevalonic acid in human plasma. | 2011 | Biomed. Chromatogr. | pmid:21110384 |
| Banfi C et al. | Statins prevent tissue factor induction by protease-activated receptors 1 and 2 in human umbilical vein endothelial cells in vitro. | 2011 | J. Thromb. Haemost. | pmid:21605334 |
| Martinez-Moya P et al. | Proteomic analysis of the carotenogenic yeast Xanthophyllomyces dendrorhous. | 2011 | BMC Microbiol. | pmid:21669001 |
| Musso A et al. | Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survival. | 2011 | Haematologica | pmid:20884711 |
| Jang HJ et al. | Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. | 2011 | Microb. Cell Fact. | pmid:21801353 |
| Leichner GS et al. | Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. | 2011 | J. Biol. Chem. | pmid:21778231 |
| Simkin AJ et al. | Peroxisomal localisation of the final steps of the mevalonic acid pathway in planta. | 2011 | Planta | pmid:21655959 |
| Barta ML et al. | Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. | 2011 | J. Biol. Chem. | pmid:21561869 |
| Vallianou I et al. | Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. | 2011 | PLoS ONE | pmid:22073134 |
| Kaneko M et al. | Effect of farnesol on mevalonate pathway of Staphylococcus aureus. | 2011 | J. Antibiot. | pmid:21772307 |
| Maki KC et al. | Effects of soy protein on lipoprotein lipids and fecal bile acid excretion in men and women with moderate hypercholesterolemia. | 2010 Nov-Dec | J Clin Lipidol | pmid:21122701 |
| Camps D | [Controversies regarding the use of statins in the acute coronary syndrome]. | 2010 Aug-Sep | Med Intensiva | pmid:20538377 |
| Omar SH | Oleuropein in olive and its pharmacological effects. | 2010 Apr-Jun | Sci Pharm | pmid:21179340 |
| Morrone D et al. | Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19777230 |
| Fukunaga M et al. | Mast cell death induced by 24(S),25-epoxycholesterol. | 2010 | Exp. Cell Res. | pmid:20854813 |
| Bouvier-Navé P et al. | Involvement of the phospholipid sterol acyltransferase1 in plant sterol homeostasis and leaf senescence. | 2010 | Plant Physiol. | pmid:19923239 |
| Honour JW | Steroid assays in paediatric endocrinology. | 2010 | J Clin Res Pediatr Endocrinol | pmid:21274330 |
| Head BP et al. | Loss of caveolin-1 accelerates neurodegeneration and aging. | 2010 | PLoS ONE | pmid:21203469 |
| Guella G et al. | Structures, biological activities and phylogenetic relationships of terpenoids from marine ciliates of the genus Euplotes. | 2010 | Mar Drugs | pmid:20714425 |
| Jana S and Shekhawat GS | Anethum graveolens: An Indian traditional medicinal herb and spice. | 2010 | Pharmacogn Rev | pmid:22228959 |
| Zheng Z et al. | Improvement of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial reactive oxygen species pathway mediated by peroxisome proliferator-activated receptor gamma coactivator 1alpha. | 2010 | Diabetes | pmid:20566666 |
| Liu Q et al. | Dynamics of lamin-A processing following precursor accumulation. | 2010 | PLoS ONE | pmid:20526372 |
| Aoyama T et al. | Pharmacokinetic/pharmacodynamic modeling and simulation of rosuvastatin using an extension of the indirect response model by incorporating a circadian rhythm. | 2010 | Biol. Pharm. Bull. | pmid:20522984 |
| Jameson JM et al. | A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes. | 2010 | Cell. Immunol. | pmid:20483407 |
| Hughes M et al. | Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP. | 2010 | J. Neurochem. | pmid:20477946 |
| Targett-Adams P et al. | Lipid metabolism and HCV infection. | 2010 | Viruses | pmid:21994676 |
| Snoeren TA et al. | The herbivore-induced plant volatile methyl salicylate negatively affects attraction of the parasitoid Diadegma semiclausum. | 2010 | J. Chem. Ecol. | pmid:20407809 |
| Lefurgy ST et al. | Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae. | 2010 | J. Biol. Chem. | pmid:20404339 |
| Clendening JW et al. | Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma. | 2010 | Blood | pmid:20360469 |
| Yang Z et al. | Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. | 2010 | Int. J. Cancer | pmid:19626588 |
| Domoki F et al. | Rosuvastatin induces delayed preconditioning against L-glutamate excitotoxicity in cultured cortical neurons. | 2010 | Neurochem. Int. | pmid:19931334 |
| De Leo L et al. | Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches. | 2010 | Pharmacol. Res. | pmid:20206266 |
| Tisch D and Schmoll M | Light regulation of metabolic pathways in fungi. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19915832 |
| Coscia M et al. | Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. | 2010 | J. Cell. Mol. Med. | pmid:19818098 |
| Kojima Y et al. | Pitavastatin decreases the expression of endothelial lipase both in vitro and in vivo. | 2010 | Cardiovasc. Res. | pmid:20045866 |
| Liu YJ et al. | Simvastatin ameliorates rat cerebrovascular remodeling during hypertension via inhibition of volume-regulated chloride channel. | 2010 | Hypertension | pmid:20644009 |
| Kones R | Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective. | 2010 | Drug Des Devel Ther | pmid:21267417 |
| Hooff GP et al. | Isoprenoids, small GTPases and Alzheimer's disease. | 2010 | Biochim. Biophys. Acta | pmid:20382260 |
| Mitrofan LM et al. | Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells. | 2010 | J. Biol. Chem. | pmid:19875454 |
| Rossi J et al. | Laminar shear stress prevents simvastatin-induced adhesion molecule expression in cytokine activated endothelial cells. | 2010 | Eur. J. Pharmacol. | pmid:20863785 |
| Quist-Paulsen P | Statins and inflammation: an update. | 2010 | Curr. Opin. Cardiol. | pmid:20421792 |
| Kassan M et al. | In vitro antioxidant activity of pravastatin provides vascular protection. | 2010 | Eur. J. Pharmacol. | pmid:20044990 |
| Kocsis GF et al. | Expression of genes related to oxidative/nitrosative stress in mouse hearts: effect of preconditioning and cholesterol diet. | 2010 | Med. Sci. Monit. | pmid:20037483 |
| Endo A | A historical perspective on the discovery of statins. | 2010 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:20467214 |
| Hooff GP et al. | Modulation of cholesterol, farnesylpyrophosphate, and geranylgeranylpyrophosphate in neuroblastoma SH-SY5Y-APP695 cells: impact on amyloid beta-protein production. | 2010 | Mol. Neurobiol. | pmid:20405344 |
| Woo IS et al. | Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells. | 2010 | Neurosci. Lett. | pmid:20298756 |
| Asadollahi MA et al. | Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae. | 2010 | Biotechnol. Bioeng. | pmid:20091767 |
| Lee SK et al. | Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20043868 |
| Huang M et al. | Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03. | 2010 | Plant Physiol. | pmid:20463089 |
| Weerasinghe S and Samantha Dassanayake R | Simulation of structural and functional properties of mevalonate diphosphate decarboxylase (MVD). | 2010 | J Mol Model | pmid:19653015 |