Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Bergstrom JD et al. | Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase. | 2000 | Arch. Biochem. Biophys. | pmid:10620343 |
Szkopińska A et al. | The regulation of activity of main mevalonic acid pathway enzymes: farnesyl diphosphate synthase, 3-hydroxy-3-methylglutaryl-CoA reductase, and squalene synthase in yeast Saccharomyces cerevisiae. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10623644 |
Aboushadi N et al. | Characterization of peroxisomal 3-hydroxy-3-methylglutaryl coenzyme A reductase in UT2 cells: sterol biosynthesis, phosphorylation, degradation, and statin inhibition. | 2000 | Biochemistry | pmid:10625499 |
Wagner AH et al. | Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation. | 2000 | Arterioscler. Thromb. Vasc. Biol. | pmid:10634801 |
Lindenthal B and von Bergmann K | Urinary excretion and serum concentration of mevalonic acid during acute intake of alcohol. | 2000 | Metab. Clin. Exp. | pmid:10647065 |
Kuzuyama T et al. | Cloning and characterization of 1-deoxy-D-xylulose 5-phosphate synthase from Streptomyces sp. Strain CL190, which uses both the mevalonate and nonmevalonate pathways for isopentenyl diphosphate biosynthesis. | 2000 | J. Bacteriol. | pmid:10648511 |
Haratake A et al. | Topical mevalonic acid stimulates de novo cholesterol synthesis and epidermal permeability barrier homeostasis in aged mice. | 2000 | J. Invest. Dermatol. | pmid:10651982 |
Cvejić JH and Rohmer M | CO2 as main carbon source for isoprenoid biosynthesis via the mevalonate-independent methylerythritol 4-phosphate route in the marine diatoms Phaeodactylum tricornutum and Nitzschia ovalis. | 2000 | Phytochemistry | pmid:10656403 |
pmid:10665838 | ||||
Hanley K et al. | Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription. | 2000 | J. Invest. Dermatol. | pmid:10692116 |
Lambert M and Bui ND | Dexamethasone-induced decrease in HMG-CoA reductase and protein-farnesyl transferase activities does not impair ras processing in AR 4-2J cells. | 1999 | Mol. Cell. Biochem. | pmid:10706000 |
pmid:10728920 | ||||
Turunen M et al. | Influence of peroxisome proliferator-activated receptor alpha on ubiquinone biosynthesis. | 2000 | J. Mol. Biol. | pmid:10731415 |
Flach J et al. | The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10733934 |
Hashimoto F et al. | Changes in isoprenoid lipid synthesis by gemfibrozil and clofibric acid in rat hepatocytes. | 2000 | Biochem. Pharmacol. | pmid:10736420 |
Coppens I et al. | Toxoplasma gondii exploits host low-density lipoprotein receptor-mediated endocytosis for cholesterol acquisition. | 2000 | J. Cell Biol. | pmid:10747095 |
Tanaka T et al. | Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition. | 2000 | J. Neurosci. | pmid:10751437 |
pmid:10774794 | ||||
Woo JT et al. | Compactin suppresses bone resorption by inhibiting the fusion of prefusion osteoclasts and disrupting the actin ring in osteoclasts. | 2000 | J. Bone Miner. Res. | pmid:10780857 |
Leonardsen L et al. | Effect of inhibition of sterol delta 14-reductase on accumulation of meiosis-activating sterol and meiotic resumption in cumulus-enclosed mouse oocytes in vitro. | 2000 | J. Reprod. Fertil. | pmid:10793639 |
Tasevski V et al. | Mitogenic effect of lithium in FRTL-5 cells can be reversed by blocking de novo cholesterol synthesis and subsequent signal transduction. | 2000 | Thyroid | pmid:10807058 |
pmid:10814523 | ||||
RodrÃguez-Concepción M et al. | Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. | 2000 | FEBS Lett. | pmid:10818234 |
Vishnuvardhan D and Beinfeld MC | Lovastatin is a potent inhibitor of cholecystokinin secretion in endocrine tumor cells in culture. | 2000 | Peptides | pmid:10822111 |
Ashar HR et al. | Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules. | 2000 | J. Biol. Chem. | pmid:10852915 |
pmid:10856525 | ||||
Raal FJ et al. | Inhibition of cholesterol synthesis by atorvastatin in homozygous familial hypercholesterolaemia. | 2000 | Atherosclerosis | pmid:10856535 |
Schulte AE et al. | Purification and characterization of mevalonate kinase from suspension-cultured cells of Catharanthus roseus (L.) G. Don. | 2000 | Arch. Biochem. Biophys. | pmid:10860546 |
Montalvetti A et al. | Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase. | 2000 | Biochem. J. | pmid:10861207 |
pmid:10872206 | ||||
Stickney JT and Buss JE | Murine guanylate-binding protein: incomplete geranylgeranyl isoprenoid modification of an interferon-gamma-inducible guanosine triphosphate-binding protein. | 2000 | Mol. Biol. Cell | pmid:10888661 |
Takagi M et al. | A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190. | 2000 | J. Bacteriol. | pmid:10894721 |
Wilding EI et al. | Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci. | 2000 | J. Bacteriol. | pmid:10894743 |
pmid:10896295 | ||||
pmid:10896296 | ||||
pmid:10899 | ||||
pmid:10908155 | ||||
pmid:10917872 | ||||
Hirai N et al. | Biosynthesis of abscisic acid by the non-mevalonate pathway in plants, and by the mevalonate pathway in fungi. | 2000 | Biosci. Biotechnol. Biochem. | pmid:10945263 |
Nilsson A | Increased cholesterol-ester formation during forced cholesterol synthesis in rat hepatocytes. | 1975 | Eur. J. Biochem. | pmid:1097241 |
Itoh D et al. | Nonequivalent labeling of the phytyl side chain of chlorophyll a in callus of the hornwort Anthoceros punctatus. | 2000 | J. Nat. Prod. | pmid:10978203 |
Ikeda U et al. | Fluvastatin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cells. | 2000 | Hypertension | pmid:10988259 |
Shimizu I and Katsuki H | Effect of temperature on ergosterol biosynthesis in yeast. | 1975 | J. Biochem. | pmid:1099086 |
Moreau JP et al. | Biosynthesis of sterols by a yeast homogenate. Incorporation of mevalonic acid into cholesta-5,7,24-trien-3beta-ol and 5alpha-cholesta-7,24-dien-3beta-ol. | 1975 | Eur. J. Biochem. | pmid:1100393 |
Hernández-Perera O et al. | Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells. | 2000 | Circ. Res. | pmid:11009568 |
Hausding M et al. | Inhibition of small G proteins of the rho family by statins or clostridium difficile toxin B enhances cytokine-mediated induction of NO synthase II. | 2000 | Br. J. Pharmacol. | pmid:11015307 |
pmid:11035257 | ||||
Smit A and Mushegian A | Biosynthesis of isoprenoids via mevalonate in Archaea: the lost pathway. | 2000 | Genome Res. | pmid:11042147 |
pmid:11053993 | ||||
pmid:11058703 |