Mevalonic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
Authors | Title | Published | Journal | PubMed Link |
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Yang J et al. | Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. | 2012 | PLoS ONE | pmid:22558074 |
Thurnher M et al. | Novel aspects of mevalonate pathway inhibitors as antitumor agents. | 2012 | Clin. Cancer Res. | pmid:22529099 |
Hong SY et al. | Isoprene hydrocarbons production upon heterologous transformation of Saccharomyces cerevisiae. | 2012 | J. Appl. Microbiol. | pmid:22519412 |
Iwata A et al. | Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells. | 2012 | Clin. Exp. Immunol. | pmid:22471285 |
Shimane M et al. | Mevalonate-dependent enzymatic synthesis of amorphadiene driven by an ATP-regeneration system using polyphosphate kinase. | 2012 | Biosci. Biotechnol. Biochem. | pmid:22878192 |
Fu X et al. | Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits. | 2012 | J. Exp. Bot. | pmid:21994170 |
Garjani A et al. | Ambivalent effects of atorvastatin on angiogenesis, epidermal cell proliferation and tumorgenesis in animal models. | 2012 | Iran. Biomed. J. | pmid:22801278 |
Ginestier C et al. | p53 and cancer stem cells: the mevalonate connexion. | 2012 | Cell Cycle | pmid:22751434 |
Paintlia AS et al. | Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis. | 2012 | Am. J. Pathol. | pmid:22796435 |
Fatima T et al. | Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. | 2012 | PLoS ONE | pmid:22558083 |
Barta ML et al. | Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. | 2012 | Biochemistry | pmid:22734632 |
Yokota K et al. | Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners. | 2011 Jan-Feb | Clin. Exp. Rheumatol. | pmid:21345291 |
Singh NK et al. | 12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation. | 2011 | Blood | pmid:21841162 |
Ma SM et al. | Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases. | 2011 | Metab. Eng. | pmid:21810477 |
Yu F et al. | Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis. | 2011 | Cell. Mol. Life Sci. | pmid:20730551 |
Luo H et al. | Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. | 2011 | BMC Genomics | pmid:22369100 |
Youn YN et al. | Impact of High-Dose Statin Pretreatment in Patients with Stable Angina during Off-Pump Coronary Artery Bypass. | 2011 | Korean J Thorac Cardiovasc Surg | pmid:22263153 |
Odom AR | Five questions about non-mevalonate isoprenoid biosynthesis. | 2011 | PLoS Pathog. | pmid:22216001 |
Rauthan M and Pilon M | The mevalonate pathway in C. elegans. | 2011 | Lipids Health Dis | pmid:22204706 |
Emma F et al. | Renal mitochondrial cytopathies. | 2011 | Int J Nephrol | pmid:21811680 |
Ageenko NV et al. | Expression of Pigment Cell-Specific Genes in the Ontogenesis of the Sea Urchin Strongylocentrotus intermedius. | 2011 | Evid Based Complement Alternat Med | pmid:21804858 |
Cheng G et al. | Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. | 2011 | Cancer Biol. Ther. | pmid:21799303 |
Peng LF et al. | Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. | 2011 | J. Infect. Dis. | pmid:21791663 |
Bajgain P et al. | Transcriptome characterization and polymorphism detection between subspecies of big sagebrush (Artemisia tridentata). | 2011 | BMC Genomics | pmid:21767398 |
Scheller EL et al. | Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production. | 2011 | J. Cell. Biochem. | pmid:21751240 |
Song JX et al. | Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway. | 2011 | J. Cardiovasc. Pharmacol. | pmid:21052011 |
Zhang B et al. | A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. | 2011 | Biochemistry | pmid:21438569 |
Kim RH et al. | Bisphosphonates induce senescence in normal human oral keratinocytes. | 2011 | J. Dent. Res. | pmid:21427353 |
Kyathanahalli CN and Kowluru A | A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGEâ‚‚. | 2011 | Biochem. Pharmacol. | pmid:21406184 |
Zhao Y et al. | Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita. | 2011 | J. Invest. Dermatol. | pmid:21390048 |
Blankier S et al. | The role of atorvastatin in regulating the immune response leading to vascular damage in a model of Kawasaki disease. | 2011 | Clin. Exp. Immunol. | pmid:21361911 |
Ghavami S et al. | Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. | 2011 | PLoS ONE | pmid:21304979 |
Ignea C et al. | Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. | 2011 | Microb. Cell Fact. | pmid:21276210 |
Tuckow AP et al. | Simvastatin represses protein synthesis in the muscle-derived Câ‚‚Câ‚â‚‚ cell line with a concomitant reduction in eukaryotic initiation factor 2B expression. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:21224482 |
Sawai S and Saito K | Triterpenoid biosynthesis and engineering in plants. | 2011 | Front Plant Sci | pmid:22639586 |
Nishikawa Y et al. | Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages. | 2011 | J. Vet. Med. Sci. | pmid:21187676 |
Li YY et al. | Zoledronic acid induces cell-cycle prolongation in murine lung cancer cells by perturbing cyclin and Ras expression. | 2011 | Anticancer Drugs | pmid:20926944 |
Liu Q et al. | Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana. | 2011 | PLoS ONE | pmid:21858047 |
Jouneau S et al. | Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. | 2011 | PLoS ONE | pmid:21826199 |
Llacuna L et al. | Targeting cholesterol at different levels in the mevalonate pathway protects fatty liver against ischemia-reperfusion injury. | 2011 | J. Hepatol. | pmid:21145825 |
Hamada M et al. | Antithrombotic properties of pravastatin reducing intra-thrombus fibrin deposition under high shear blood flow conditions. | 2011 | Thromb. Haemost. | pmid:21136018 |
Hao Q et al. | Synthesis and anti-hypercholesterolemic evaluations of calcium salts of 4-substituted quinoline-based mevalonic acid. | 2011 | Chem Biol Drug Des | pmid:21791012 |
Castella B et al. | Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells. | 2011 | J. Immunol. | pmid:21753152 |
Okada K | The biosynthesis of isoprenoids and the mechanisms regulating it in plants. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21737944 |
Kindt E et al. | The validation of a simple LC/MS/MS method for determining the level of mevalonic acid in human plasma. | 2011 | Biomed. Chromatogr. | pmid:21110384 |
Jang HJ et al. | Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. | 2011 | Microb. Cell Fact. | pmid:21801353 |
Leichner GS et al. | Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. | 2011 | J. Biol. Chem. | pmid:21778231 |
Simkin AJ et al. | Peroxisomal localisation of the final steps of the mevalonic acid pathway in planta. | 2011 | Planta | pmid:21655959 |
Kaneko M et al. | Effect of farnesol on mevalonate pathway of Staphylococcus aureus. | 2011 | J. Antibiot. | pmid:21772307 |
Yanae M et al. | Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. | 2011 | J. Exp. Clin. Cancer Res. | pmid:21831290 |