| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Banthorpe DV et al. | Biosynthesis of geraniol and nerol and beta-D-glucosides in Pelargonium graveolens and Rosa dilecta. | 1972 | Biochem. J. | pmid:4348258 |
| Heintz R et al. | Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4344813 |
| pmid:4343214 | ||||
| Sharma RK et al. | Steroidogenesis in isolated adrenal cells of rat. 3. Morphological and biochemical correlation of cholesterol and cholesterol ester content in ACTH and N6-2'-O-dibutyryl-adenosine-3',5'-monophosphate activated adrenal cells. | 1972 | Endocrinology | pmid:4340613 |
| Aiyar AS and Olson RE | Enhancement of ubiquinone-9 biosynthesis in rat-liver slices by exogenous mevalonate. | 1972 | Eur. J. Biochem. | pmid:4340277 |
| Williams CD and Avigan J | In vitro effects of serum proteins and lipids on lipid synthesis in human skin fibroblasts and leukocytes grown in culture. | 1972 | Biochim. Biophys. Acta | pmid:4338876 |
| Stone KJ and Strominger JL | Inhibition of sterol biosynthesis by bacitracin. | 1972 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4338587 |
| Momose K and Rudney H | 3-Polyprenyl-4-hydroxybenzoate synthesis in the inner membrane of mitochondria from p-hydroxybenzoate and isopentenylpyrophosphate. A demonstration of isoprenoid synthesis in rat liver mitochondria. | 1972 | J. Biol. Chem. | pmid:4338233 |
| Slakey LL et al. | The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene. | 1972 | J. Biol. Chem. | pmid:4337504 |
| Green TR and Baisted DJ | Development of the squalene-synthesizing system during early stages of pea seed germination. | 1971 | Biochem. J. | pmid:4335540 |
| Skilleter DN and Kekwick RG | The enzymes forming isopentenyl pyrophosphate from 5-phosphomevalonate (mevalonate 5-phosphate) in the latex of Hevea brasiliensis. | 1971 | Biochem. J. | pmid:4333851 |
| Logan DM | Thermal and pH stability of 2 -isopentenyl pyrophosphate. | 1972 | J. Lipid Res. | pmid:4333821 |
| Bloxham DP and Akhtar M | Studies on the control of cholesterol biosynthesis: the adenosine 3':5'-cyclic monophosphate-dependent accumulation of a steroid carboxylic acid. | 1971 | Biochem. J. | pmid:4331371 |
| Fall RR and West CA | Purification and properties of kaurene synthetase from Fusarium moniliforme. | 1971 | J. Biol. Chem. | pmid:4331199 |
| Goodwin TW | Biosynthesis of carotenoids and plant triterpenes. | 1971 | Biochem. J. | pmid:4331177 |
| Goldfarb S and Pitot HC | The regulation of beta-hydroxy-beta-methylglutaryl coenzyme A reductase in Morris hepatomas 5123C, 7800, and 9618A. | 1971 | Cancer Res. | pmid:4330433 |
| Siperstein MD | Cholesterol and cancer. | 1970 | Trans. Am. Clin. Climatol. Assoc. | pmid:4330034 |
| Kandutsch AA and Hancock RL | Regulation of the rate of sterol synthesis and the level of beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity in mouse liver and hepatomas. | 1971 | Cancer Res. | pmid:4328734 |
| Maragoudakis ME | On the mode of action of lipid-lowering agents. VI. Inhibition of lipogenesis in rat mammary gland cell culture. | 1971 | J. Biol. Chem. | pmid:4327196 |
| Grossi-Paoletti E et al. | Lipids in brain tumors. | 1971 | J. Neurosurg. | pmid:4323146 |
| Flint AP | The activity and kinetic properties of mevalonate kinase in superovulated rat ovary. | 1970 | Biochem. J. | pmid:4321929 |
| Bensch WR and Rodwell VW | Purification and properties of 3-hydroxy-3-methylglutaryl coenzyme A reductase from Pseudomonas. | 1970 | J. Biol. Chem. | pmid:4321764 |
| Hammond RK and White DC | Inhibition of vitamin K2 and carotenoid synthesis in Staphylococcus aureus by diphenylamine. | 1970 | J. Bacteriol. | pmid:4319835 |
| Gough DP and Hemming FW | The characterization and stereochemistry of biosynthesis of dolichols in rat liver. | 1970 | Biochem. J. | pmid:4319540 |
| Heinstein PF et al. | Biosynthesis of gossypol. Incorporation of mevalonate-2-14C and isoprenyl pyrophosphates. | 1970 | J. Biol. Chem. | pmid:4318479 |
| Smith PF and Smith MR | Cholesterol inhibition of isopentenyl pyrophosphate delta3, delta2-isomerase in Mycoplasma laidlawii. | 1970 | J. Bacteriol. | pmid:4316364 |
| Gough DP and Hemming FW | The stereochemistry of betulaprenol biosynthesis. | 1970 | Biochem. J. | pmid:4315982 |
| pmid:4309789 | ||||
| Buggy MJ et al. | Stereochemistry of phytoene biosynthesis by isolated chloroplasts. | 1969 | Biochem. J. | pmid:4309532 |
| Rudney H | The biosynthesis of terpenoid quinones. | 1969 | Biochem. J. | pmid:4308944 |
| Schweppe JS and Jungmann RA | Hormones and cholesterol ester metabolism. | 1969 | J Am Geriatr Soc | pmid:4308733 |
| Noddle RC and Robinson DR | Biosynthesis of abscisic acid: incorporation of radioactivity from [2-14C]mevalonic acid by intact fruit. | 1969 | Biochem. J. | pmid:4308332 |
| pmid:4307824 | ||||
| Kelley MT et al. | Biosynthesis of squalene and cholesterol by cell-free extracts of adult rat brain. | 1969 | J. Lipid Res. | pmid:4305711 |
| pmid:4303098 | ||||
| Dorsey JK and Porter JW | The inhibition of mevalonic kinase by geranyl and farnesyl pyrophosphates. | 1968 | J. Biol. Chem. | pmid:4300840 |
| pmid:4300693 | ||||
| pmid:4297772 | ||||
| Rees HH et al. | Studies in phytosterol biosynthesis. Mechanism of biosynthesis of cycloartenol. | 1968 | Biochem. J. | pmid:4297048 |
| pmid:4296960 | ||||
| Elwood JC and Morris HP | Lack of adaptation in lipogenesis by hepatoma 9121. | 1968 | J. Lipid Res. | pmid:4296416 |
| pmid:4295982 | ||||
| Stone KJ and Hemming FW | The stereochemistry of hexahydroprenol, ubiquinone and ergosterol biosynthesis in the mycelium of Aspergillus fumigatus Fresenius. | 1967 | Biochem. J. | pmid:4292001 |
| pmid:4291952 | ||||
| Gaylor JL et al. | Preparation and properties of a cell-free system from rat skin that catalyzes sterol biosynthesis. | 1966 | J. Lipid Res. | pmid:4290536 |
| Nightingale MS et al. | Testicular sterols. VI. Incorporation of mevalonate into squalene and sterols by cell-free preparations of testicular tissue. | 1967 | J. Biol. Chem. | pmid:4290213 |
| Siddiqi MA and Rodwell VW | Bacterial metabolism of mevalonic acid. | 1967 | J. Bacteriol. | pmid:4289807 |
| Henrikson CV and Smith PF | Conversion of mevalonic acid to gamma, gamma-dimethylallyl pyrophosphate by Mycoplasma. | 1966 | J. Bacteriol. | pmid:4288495 |
| Cornforth JW et al. | Studies on the biosynthesis of cholesterol. XX. Steric course of decarboxylation of 5-pyrophosphomevalonate and of the carbon to carbon bond formation in the biosynthesis of farnesyl pyrophosphate. | 1966 | J. Biol. Chem. | pmid:4288360 |
| pmid:4287665 | ||||
| Stone KJ and Hemming FW | The incorporation of [2-14C, 4R-3H1] mevalonate and [2-14C, 4S-3H1] mevalonate into squalene, ubiquinone and ergosterol of Aspergillus fumigatus Fresenius. | 1965 | Biochem. J. | pmid:4284430 |
| Niemiro R and Fumagalli R | Studies on the inhibitory mechanism of some hypocholesterolemic agents on 7-dehydrocholesterol delta-7-bond reductase activity. | 1965 | Biochim. Biophys. Acta | pmid:4284414 |
| Dugan RE et al. | Regulation of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A reductase by the interplay of hormones. | 1974 | Arch. Biochem. Biophys. | pmid:4275665 |
| Bhavnani BR and Short RV | Formation of steroids by the pregnant mare. IV. Metabolism of 14 C-mevalonic acid and 3 H-dehydroisoandrosterone injected into the fetal circulation. | 1973 | Endocrinology | pmid:4266621 |
| Ono T and Imai Y | Effects of steroid hormones on synthesis of cholesterol in vitro. | 1971 | J. Biochem. | pmid:4254538 |
| Thorne KJ and Barker DC | Bactoprenol, ATPase and acetate activating enzymes of a vesicular fraction from Lactobacillus casei. | 1969 | Eur. J. Biochem. | pmid:4244061 |
| van Leusden HA and Villee CA | Formation of estrogens by hydatidiform moles in vitro. | 1966 | J. Clin. Endocrinol. Metab. | pmid:4224151 |
| Tamm C | Transformation of organic compounds by microbial enzymes. | 1974 | FEBS Lett. | pmid:4214719 |
| pmid:4212301 | ||||
| pmid:4212109 | ||||
| Thorne KJ et al. | An investigation by autoradiography and electron microscopy of the localization of prenols in Lactobacillus casei. | 1974 | J. Gen. Microbiol. | pmid:4207873 |
| Bortz WM | On the control of cholesterol synthesis. | 1973 | Metab. Clin. Exp. | pmid:4206254 |
| Shechter I and West CA | Biosynthesis of gibberellins. IV. Biosynthesis of cyclic diterpenes from trans-geranylgeranyl pyrophosphate. | 1969 | J. Biol. Chem. | pmid:4183095 |
| Gianelly AA and Terner C | Inhibition of cholesterol biosynthesis by dehydroepiandrosterone in lactating mammary gland. | 1968 | Endocrinology | pmid:4177463 |
| Steinberg D et al. | Studies on the metabolic error in Refsum's disease. | 1967 | J. Clin. Invest. | pmid:4164676 |
| pmid:4158442 | ||||
| Muscio F et al. | Prequalene pyrophosphate. A normal intermediate in squalene biosynthesis. | 1974 | J. Biol. Chem. | pmid:4152099 |
| Hulcher FH and Oleson WH | Simplified spectrophotometric assay for microsomal 3-hydroxy-3-methylglutaryl CoA reductase by measurement of coenzyme A. | 1973 | J. Lipid Res. | pmid:4147523 |
| Brown MS et al. | 3-Hydroxy-3-methylglutaryl coenzyme A reductase. Solubilization and purification of a cold-sensitive microsomal enzyme. | 1973 | J. Biol. Chem. | pmid:4146267 |
| Beedle AS et al. | Studies on the biosynthesis of tetrahymanol in Tetrahymena pyriformis. The mechanism of inhibition by cholesterol. | 1974 | Biochem. J. | pmid:4140721 |
| Kawaguchi A et al. | Subcellular distribution of sesterterpene- and sterol-biosynthesizing activities in Cochliobolus heterostrophus. | 1973 | Biochim. Biophys. Acta | pmid:4120185 |
| Holmlund CE | On the mechanism of growth inhibition of Tetrahymena pyriformis by steroids. | 1971 | Biochim. Biophys. Acta | pmid:4108656 |
| pmid:4108155 | ||||
| Rilling HC | The mechanism of the condensation reactions of cholesterol biosynthesis. Fourth Morton lecture. | 1985 | Biochem. Soc. Trans. | pmid:4092833 |
| Patel DD and Knight BL | The effect of mevalonate on 3-hydroxy-3-methylglutaryl-CoA reductase activity and the absolute rate of cholesterol biosynthesis in human monocyte-derived macrophages. | 1985 | Eur. J. Biochem. | pmid:4065145 |
| Steen G et al. | Isoprenoid biosynthesis in multiple sclerosis. | 1985 | Acta Neurol. Scand. | pmid:4061053 |
| Stone BG et al. | Regulation of rat biliary cholesterol secretion by agents that alter intrahepatic cholesterol metabolism. Evidence for a distinct biliary precursor pool. | 1985 | J. Clin. Invest. | pmid:4056052 |
| Saucier SE et al. | Identification of regulatory oxysterols, 24(S),25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts. | 1985 | J. Biol. Chem. | pmid:4055791 |
| Watson JA et al. | Isoprenoid synthesis in isolated embryonic Drosophila cells. Sterol-independent regulatory signal molecule is distal to isopentenyl 1-pyrophosphates. | 1985 | J. Biol. Chem. | pmid:4055772 |
| Berger R et al. | Mevalonic aciduria: an inborn error of cholesterol biosynthesis? | 1985 | Clin. Chim. Acta | pmid:4053401 |
| Goad LJ et al. | Effect of the allylamine antifungal drug SF 86-327 on the growth and sterol synthesis of Leishmania mexicana mexicana promastigotes. | 1985 | Biochem. Pharmacol. | pmid:4052119 |
| Herscovitz H and Tietz A | The availability of different sources of cholesterol for bile acid synthesis by cultured chick embryo hepatocytes. | 1985 | Biochim. Biophys. Acta | pmid:4041475 |
| Ryder NS | Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent. | 1985 | Antimicrob. Agents Chemother. | pmid:4039119 |
| Okada K et al. | Effect of 4-(4'-chlorobenzyloxy)benzyl nicotinate (KCD-232) on cholesterol metabolism in rats. | 1985 | Biochem. Pharmacol. | pmid:4038342 |
| Goad LJ et al. | Sterols of ketoconazole-inhibited Leishmania mexicana mexicana promastigotes. | 1985 | Mol. Biochem. Parasitol. | pmid:4033689 |
| McNamara DJ et al. | Role of the kidneys in the metabolism of plasma mevalonate. Studies in humans and in rhesus monkeys. | 1985 | J. Clin. Invest. | pmid:4019781 |
| Peffley D and Sinensky M | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis by a non-sterol mevalonate-derived product in Mev-1 cells. Apparent translational control. | 1985 | J. Biol. Chem. | pmid:4019518 |
| Gill JF et al. | Mevalonate utilization in Pseudomonas sp. M. Purification and characterization of an inducible 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1985 | J. Biol. Chem. | pmid:4019479 |
| Deneris ES et al. | Acid-catalyzed formation of isoprene from a mevalonate-derived product using a rat liver cytosolic fraction. | 1985 | J. Biol. Chem. | pmid:3968076 |
| Vuoristo M and Miettinen TA | Enhanced synthesis of cholesterol and its precursors in jejunal mucosa in coeliac disease. | 1986 | Gut | pmid:3957109 |
| Pentchev PG et al. | The cholesterol storage disorder of the mutant BALB/c mouse. A primary genetic lesion closely linked to defective esterification of exogenously derived cholesterol and its relationship to human type C Niemann-Pick disease. | 1986 | J. Biol. Chem. | pmid:3949747 |
| pmid:3947101 | ||||
| Borgford TJ et al. | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and lipid metabolism in a concanavalin A-resistant Chinese hamster ovary cell line. | 1986 | Arch. Biochem. Biophys. | pmid:3947077 |
| pmid:3941316 | ||||
| Haro D et al. | Rat liver HMG CoA reductase, a glycoprotein of the endoplasmic reticulum, is in equilibrium between monomeric and dimeric forms. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3933506 |
| Wilton DC | The effect of excess mevalonic acid on ubiquinone and tetrahymanol biosynthesis in Tetrahymena pyriformis. | 1985 | Biochem. J. | pmid:3929773 |
| Gillies PJ and Lee KP | Effects of hexafluoroacetone on Leydig cell steroidogenesis and spermatogenesis in the rat. | 1985 | Exp. Mol. Pathol. | pmid:3922783 |
| pmid:3865612 | ||||
| Maltese WA and Sheridan KM | Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis. | 1985 | J. Cell. Physiol. | pmid:3851809 |
| Clarke CF et al. | Transcriptional regulation of the 3-hydroxy-3-methylglutaryl coenzyme A reductase gene in rat liver. | 1985 | J. Biol. Chem. | pmid:3850901 |