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Biosynthesis of various sterols, sterol esters, and squalene from [14C]mevalonate by normal swine intima and media in vitro: a comparative study. |
1976 |
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1976 |
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The effect of insulin and glucose on sterol synthesis in cultured rat arterial smooth muscle cells. |
1977 |
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Isolation and partial characterization of a cholesterol-requiring mutant of Chinese hamster ovary cells. |
1977 |
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Measurement of daily cholesterol synthesis rates in man by assay of the fractional conversion of mevalonic acid to cholesterol. |
1977 |
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1978 |
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Evidence from cell-free systems for differences in the sterol biosynthetic pathway of Rhizoctonia solani and Phytophthora cinnamomi. |
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1978 |
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Formation of steroids by the pregnant mare. VI. Metabolism of [14C]farnesyl pyrophosphate and [3H]dehydroepiandrosterone injected into the fetus. |
1978 |
Endocrinology |
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The effect of dietary fat supplements on cholesterol metabolism in ruminants. |
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Copper deficiency and cholesterol metabolism in the rat. |
1978 |
Atherosclerosis |
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On the stereospecificity of microsomal "26"-hydroxylation in bile acid biosynthesis. |
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Abnormal liver cholesteryl ester storage in a strain of golden hamsters. Possible model for studies on cholesterol metabolism. |
1978 |
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Effects of saturated and unsaturated fats given with and without dietary cholesterol on hepatic cholesterol synthesis and hepatic lipid metabolism. |
1978 |
Biochim. Biophys. Acta |
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Impairment of dolichyl saccharide synthesis and dolichol-mediated glycoprotein assembly in the aortic smooth muscle cell in culture by inhibitors of cholesterol biosynthesis. |
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On the mechanism for the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, of cholesterol 7alpha-hydroxylase and of acyl-coenzyme A:cholesterol acyltransferase by free cholesterol. |
1978 |
Biochim. Biophys. Acta |
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Compactin inhibits cholesterol synthesis in lymphocytes and intestinal mucosa from patients with familial hypercholesterolaemia. |
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High affinity Concanavalin A binding to sterol-depleted L cells. |
1979 |
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Unexpectedly low incorporation of isotopic acetate into lipids of Ehrlich ascites tumor cells cultured in lipid-poor medium. |
1979 |
Oncology |
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Effect of diosgenin on lipid metabolism in rats. |
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The metabolism of esterified cholesterol in rabbit plasma low density lipoproteins. |
1979 |
Biochim. Biophys. Acta |
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Selective labelling of two phases of axonal transport of cholesterol in the chick optic system. |
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Cholesterol synthesis in isolated rat hepatocytes. In vitro effect os sterols and bile acids. |
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1979 |
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Essential role for mevalonate synthesis in DNA replication. |
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Effect of milk constituents on hepatic cholesterol-genesis. |
1979 |
Atherosclerosis |
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Cholesterogenesis induction in human lymphocytes by sterols efflux or phytohemagglutinin stimulation : cellular division as the requirement for efficient cholesterol biosynthesis in lymphocytes. |
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Conversion of mevalonolactone to its open-chain salt by a serum enzyme. |
1979 |
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Regulation of sterol biosynthesis and lysis of cultured hepatoma cells: inhibition of lanosterol demethylation by hydroxysterols. |
1979 |
Biochem. Biophys. Res. Commun. |
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Inhibition of rat liver mevalonate pyrophosphate decarboxylase and mevalonate phosphate kinase by phenyl and phenolic compounds. |
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Determination of mevalonate in blood plasma in man and rat. Mevalonate "tolerance" tests in man. |
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Potent immunosuppression by oxidized cholesterol. |
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In vitro exchanges of esterified cholesterol between serum lipoprotein fractions: studies of humans and rabbits. |
1979 |
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Isolation of 4 alpha-methyl-5 alpha-ergosta-8,24(28)-dien-3 beta-ol from ester fractions of nutritionally deprived Neurospora crassa. |
1979 |
Steroids |
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Inhibition of human lymphocyte E-rosette formation by oxygenated sterols. |
1979 |
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The biosynthesis of ubiquinone in isolated rat heart cells. |
1979 |
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Cholesterol metabolism in diabetes: the effect of insulin on the kinetics of plasma squalene. |
1979 |
J. Clin. Endocrinol. Metab. |
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Synthesis of alpha-tocopherolquinone by the rat and its reduction by mitochondria. |
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Effects of vitamin A and ascorbic acid on in vitro cholesterol biosynthesis in the rat. |
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Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth. |
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Regulation of hamster adrenal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. |
1980 |
Endocrinology |
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Cholesterol synthesis in tissues of young and old Fisher 344 and Sprague-Dawley rats. |
1980 |
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Inhibition of human lymphocyte transformation by oxygenated sterol compounds. |
1980 |
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Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamster ovary cells. |
1980 |
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Differences in the characteristics of inhibition of lymphocyte stimulation by 25-hydroxycholesterol and by the immunoregulatory serum lipoprotein LDL-In. |
1980 |
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Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Morris hepatoma 7800 after intravenous injection of mevalonic acid. |
1980 |
Cancer Res. |
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Isopentenyladenine as a mediator of mevalonate-regulated DNA replication. |
1980 |
Proc. Natl. Acad. Sci. U.S.A. |
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Protection of cell viability and respiratory quinone levels by carotenoid in Micrococcus lysodeikticus (M. luteus). |
1980 |
J. Gen. Microbiol. |
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Cycloheximide inhibits sterol biosynthesis in cell-free preparations of rat liver. |
1980 |
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Vanadate inhibits mevalonate synthesis and activates NADH oxidation in microsomes. |
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Retention of the 4-pro-R hydrogen atom of mevalonate at C-2,2' of bacterioruberin in Halobacterium halobium. |
1980 |
Biochem. J. |
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Sterol metabolism and lymphocyte function: inhibition of endogenous sterol biosynthesis does not prevent mitogen-induced human T lymphocyte activation. |
1980 |
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Sex difference in human mevalonate metabolism. |
1980 |
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Somatic cell genetic analysis of regulation of expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. |
1980 |
Proc. Natl. Acad. Sci. U.S.A. |
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Mevalonate metabolism in pregnant rats. |
1980 |
Metab. Clin. Exp. |
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Resistance to streptolysin O in mammalian cells treated with oxygenated derivatives of cholesterol. Cholesterol content of resistant cells and recovery of streptolysin O sensitivity. |
1980 |
Biochim. Biophys. Acta |
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Biosynthesis of cholesterol and cholesterol precursors in platelets of female rats treated with oral contraceptives. |
1980 |
Biochim. Biophys. Acta |
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Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor. |
1980 |
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Elevated dolichol synthesis in mouse testes during spermatogenesis. |
1980 |
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Growth of amphotericin B-resistant hamster cell line requires exogenous cholesterol. |
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In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: enzyme phosphorylation as an early regulatory response after intragastric administration of mevalonolactone. |
1980 |
Proc. Natl. Acad. Sci. U.S.A. |
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Stereochemistry of the side chain oxidation of 5 beta-cholestane-3 alpha,7 alpha,12 alpha-triol in man. |
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Studies on the mechanisms of the rapid modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in intact liver by mevalonolactone and 25-hydroxycholesterol. |
1980 |
Biochim. Biophys. Acta |
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Regulation of cholesterol esterification and biosynthesis in monolayer cultures of normal adult rat hepatocytes. |
1980 |
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Conversion of [2-14C] mevalonate into cholesterol, lanosterol and squalene in copper-deficient rats. |
1980 |
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The role of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in the regulation of ubiquinone synthesis in human fibroblasts. |
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A deficiency of mixed function oxidase activities in the cholesterol biosynthetic pathway of human granulocytes. |
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Influence of thyroid hormone status on mevalonate metabolism in rats. |
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Secretion of very low density lipoproteins enriched in cholesteryl esters by cultured rat hepatocytes during simulation of intracellular cholesterol esterification. |
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Synthesis of delta 2-isopentenyl tRNA from mevalonate in cultured human fibroblasts. |
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