| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lin Y et al. | Differences in propionate-induced inhibition of cholesterol and triacylglycerol synthesis between human and rat hepatocytes in primary culture. | 1995 | Br. J. Nutr. | pmid:7547837 |
| Ortiz MB et al. | Mevalonate dependency of the early cell cycle mitogenic response to epidermal growth factor and prostaglandin F2 alpha in Swiss mouse 3T3 cells. | 1995 | J. Cell. Physiol. | pmid:7814446 |
| Doerner KC et al. | Regulation of cholesterol 7 alpha-hydroxylase expression by sterols in primary rat hepatocyte cultures. | 1995 | J. Lipid Res. | pmid:7665995 |
| Latruffe N et al. | Stimulation of protein kinase C activity by compactin in vascular smooth muscle cells. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7503722 |
| Yu SG et al. | Geraniol, an inhibitor of mevalonate biosynthesis, suppresses the growth of hepatomas and melanomas transplanted to rats and mice. | 1995 | J. Nutr. | pmid:7472655 |
| Corsini A et al. | Pathogenesis of atherosclerosis and the role of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. | 1995 | Am. J. Cardiol. | pmid:7604791 |
| Guyton JR et al. | Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants. | 1995 | Atherosclerosis | pmid:8770318 |
| Aspbury RA et al. | Lipid modification of signal-transducing polypeptides in the free-living nematode Caenorhabditis elegans. | 1995 | Biochem. Soc. Trans. | pmid:7758740 |
| Sekler MS and Simoni RD | Mutation in the lumenal part of the membrane domain of HMG-CoA reductase alters its regulated degradation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7818519 |
| Luján HD et al. | Isoprenylation of proteins in the protozoan Giardia lamblia. | 1995 | Mol. Biochem. Parasitol. | pmid:8538683 |
| Weber C et al. | Lovastatin induces differentiation of Mono Mac 6 cells. | 1995 | Cell Biochem. Funct. | pmid:8565148 |
| Ishikawa S et al. | Simvastatin inhibits the cellular signaling and proliferative action of arginine vasopressin in cultured rat glomerular mesangial cells. | 1995 | Endocrinology | pmid:7720643 |
| Cummings MH and Watts GF | Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in cholesteryl ester storage disease. | 1995 | Clin. Chem. | pmid:7813057 |
| Ranganathan G and Mukkada AJ | Ubiquinone biosynthesis in Leishmania major promastigotes. | 1995 | Int. J. Parasitol. | pmid:7601585 |
| Andersson M et al. | Age-dependent modifications in the metabolism of mevalonate pathway lipids in rat brain. | 1995 | Mech. Ageing Dev. | pmid:8789251 |
| Straka MS and Panini SR | Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate. | 1995 | Arch. Biochem. Biophys. | pmid:7872789 |
| Re EB et al. | Co-expression of native and introduced genes reveals cryptic regulation of HMG CoA reductase expression in Arabidopsis. | 1995 | Plant J. | pmid:7773308 |
| Schedin S et al. | Changes in the levels of dolichol and dolichyl phosphate in a murine model of Niemann-Pick's type C disease. | 1995 | J. Neurochem. | pmid:7616223 |
| Cox AD | Mutation and analysis of prenylation signal sequences. | 1995 | Meth. Enzymol. | pmid:7651143 |
| Cuthbert JA and Lipsky PE | Suppression of the proliferation of Ras-transformed cells by fluoromevalonate, an inhibitor of mevalonate metabolism. | 1995 | Cancer Res. | pmid:7712482 |
| Herold G et al. | Influence of cholesterol supply on cell growth and differentiation in cultured enterocytes (CaCo-2). | 1995 | Digestion | pmid:7895934 |
| Masters BA et al. | In vitro myotoxicity of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, pravastatin, lovastatin, and simvastatin, using neonatal rat skeletal myocytes. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7878672 |
| Crick DC et al. | Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7794274 |
| Inglese J | Prenylation-dependent targeting of G-protein-coupled receptor kinases. | 1995 | Meth. Enzymol. | pmid:7651147 |
| Kikuchi A et al. | Purification and properties of Rab3A. | 1995 | Meth. Enzymol. | pmid:8583939 |
| Schootemeijer A et al. | Relation between membrane fluidity and signal transduction in the human megakaryoblastic cell line MEG-01. | 1995 | Biochim. Biophys. Acta | pmid:7794941 |
| Cummings MH et al. | Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in obesity: a stable isotope study. | 1995 | Clin. Sci. | pmid:7720348 |
| Dalton MB et al. | The farnesyl protein transferase inhibitor BZA-5B blocks farnesylation of nuclear lamins and p21ras but does not affect their function or localization. | 1995 | Cancer Res. | pmid:7614464 |
| Roullet JB et al. | Mevalonate availability affects human and rat resistance vessel function. | 1995 | J. Clin. Invest. | pmid:7615793 |
| Sagami H et al. | A novel type of protein modification by isoprenoid-derived materials. Diphytanylglycerylated proteins in Halobacteria. | 1995 | J. Biol. Chem. | pmid:7797461 |
| Pérez-Sala D et al. | Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease. | 1995 | J. Biol. Chem. | pmid:7890761 |
| Chiloeches A et al. | Effects of lovastatin on adenylyl cyclase activity and G proteins in GH4C1 cells. | 1995 | FEBS Lett. | pmid:7890038 |
| Soma MR et al. | In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin. | 1995 | Cancer Res. | pmid:7834630 |
| Shipton CA et al. | Isoprenylation of plant proteins in vivo. Isoprenylated proteins are abundant in the mitochondria and nuclei of spinach. | 1995 | J. Biol. Chem. | pmid:7822281 |
| Dimster-Denk D et al. | Control of RAS mRNA level by the mevalonate pathway. | 1995 | Mol. Biol. Cell | pmid:7749195 |
| Rogler G et al. | Effects of fluvastatin on growth of porcine and human vascular smooth muscle cells in vitro. | 1995 | Am. J. Cardiol. | pmid:7604784 |
| Kwiterovich PO and Motevalli M | Inhibition of protein tyrosine kinase alters the effect of serum basic protein I on triacylglycerols and cholesterol differently in normal and hyperapoB fibroblasts. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7627714 |
| Schroeder WA and Johnson EA | Singlet oxygen and peroxyl radicals regulate carotenoid biosynthesis in Phaffia rhodozyma. | 1995 | J. Biol. Chem. | pmid:7629161 |
| Bernini F et al. | HMG-CoA reductase inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7670949 |
| Viganõ T et al. | Mevalonate pathway and isoprenoids regulate human bronchial myocyte proliferation. | 1995 | Eur. J. Pharmacol. | pmid:8566171 |
| Parmryd I et al. | Identification of spinach farnesyl protein transferase. Dithiothreitol as an acceptor in vitro. | 1995 | Eur. J. Biochem. | pmid:8575428 |
| Feillet C et al. | Comparative effects of simvastatin and pravastatin on cholesterol synthesis in patients with primary hypercholesterolemia. | 1995 | Atherosclerosis | pmid:8770319 |
| Corsini A et al. | Pharmacology of competitive inhibitors of HMG-CoA reductase. | 1995 | Pharmacol. Res. | pmid:7784310 |
| Thelin A et al. | Effect of squalestatin 1 on the biosynthesis of the mevalonate pathway lipids. | 1994 | Biochim. Biophys. Acta | pmid:7811707 |
| Correll CC and Edwards PA | Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo and in vitro. | 1994 | J. Biol. Chem. | pmid:8276863 |
| Munro E et al. | Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis. | 1994 | Eur. J. Clin. Invest. | pmid:7890015 |
| Aberg F et al. | Effects of clofibrate, phthalates and probucol on ubiquinone levels. | 1994 | Chem. Biol. Interact. | pmid:8194121 |
| Pfohl M et al. | Acute and chronic effects on cholesterol biosynthesis of LDL-apheresis with or without concomitant HMG-CoA reductase inhibitor therapy. | 1994 | J. Lipid Res. | pmid:7868973 |
| Kelleher JK et al. | Isotopomer spectral analysis of cholesterol synthesis: applications in human hepatoma cells. | 1994 | Am. J. Physiol. | pmid:8166258 |
| Kawata S et al. | Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2). | 1994 | Br. J. Cancer | pmid:8198962 |
| Schulz S et al. | Prenylated proteins and lymphocyte proliferation: inhibition by d-limonene related monoterpenes. | 1994 | Eur. J. Immunol. | pmid:8299679 |
| Grünler J et al. | Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins. | 1994 | Biochim. Biophys. Acta | pmid:8199197 |
| Lala A et al. | The effects of insulin on plasma mevalonate concentrations in man. | 1994 | Ann. Nutr. Metab. | pmid:7710260 |
| Gebhardt R et al. | Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells. | 1994 | Biochim. Biophys. Acta | pmid:8011681 |
| Russell-Jones DL et al. | The effect of growth hormone replacement on serum lipids, lipoproteins, apolipoproteins and cholesterol precursors in adult growth hormone deficient patients. | 1994 | Clin. Endocrinol. (Oxf) | pmid:7955441 |
| Johnson KA et al. | In vivo formation of 25-hydroxycholesterol from endogenous cholesterol after a single meal, dietary cholesterol challenge. | 1994 | J. Lipid Res. | pmid:7897321 |
| Giron MD et al. | Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8022795 |
| Ren Z and Gould MN | Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol. | 1994 | Cancer Lett. | pmid:8149348 |
| Florin-Christensen M et al. | Occurrence of specific sterols in Pneumocystis carinii. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8292026 |
| Appelkvist EL et al. | Regulation of coenzyme Q biosynthesis. | 1994 | Mol. Aspects Med. | pmid:7752843 |
| Carlberg M et al. | Mevalonate is essential for growth activation of human fibroblasts: evidence for a critical role of protein glycosylation in the prereplicative period. | 1994 | Exp. Cell Res. | pmid:8187830 |
| Hungund BL et al. | In vivo incorporation of [2-14C]mevalonic acid into rat brain complex glycolipids: characterization of glycosylsterols in mammalian brain. | 1994 | Chem. Phys. Lipids | pmid:8181105 |
| Ortiz JA et al. | Transfection of the ketogenic mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase cDNA into Mev-1 cells corrects their auxotrophy for mevalonate. | 1994 | J. Biol. Chem. | pmid:7961793 |
| Müller-Wieland D et al. | Melatonin inhibits LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8074686 |
| Hrab RV et al. | Prevention of fluvastatin-induced toxicity, mortality, and cardiac myopathy in pregnant rats by mevalonic acid supplementation. | 1994 | Teratology | pmid:7974251 |
| Sagami H et al. | Novel isoprenoid modified proteins in Halobacteria. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8093082 |
| Terkeltaub R et al. | Role of the mevalonate pathway of isoprenoid synthesis in IL-8 generation by activated monocytic cells. | 1994 | J. Leukoc. Biol. | pmid:8195701 |
| Ness GC et al. | Effect of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7 alpha hydroxylase. | 1994 | Arch. Biochem. Biophys. | pmid:7911291 |
| Sinensky M et al. | Expression of prelamin A but not mature lamin A confers sensitivity of DNA biosynthesis to lovastatin on F9 teratocarcinoma cells. | 1994 | J. Cell. Sci. | pmid:7983180 |
| Correll CC et al. | Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1994 | J. Biol. Chem. | pmid:8021239 |
| Mallat A et al. | Effect of simvastatin, an inhibitor of hydroxy-methylglutaryl coenzyme A reductase, on the growth of human Ito cells. | 1994 | Hepatology | pmid:7982659 |
| Hiser L et al. | ERG10 from Saccharomyces cerevisiae encodes acetoacetyl-CoA thiolase. | 1994 | J. Biol. Chem. | pmid:7989303 |
| Dimster-Denk D et al. | Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiae. | 1994 | Mol. Biol. Cell | pmid:7949422 |
| Wilde J and Eggerer H | Substrate and inhibitor specificity of mevalonate kinase determined with substrate analogues. | 1994 | Eur. J. Biochem. | pmid:8168534 |
| Hampton RY and Rine J | Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast. | 1994 | J. Cell Biol. | pmid:8163547 |
| Rahmatullah M and Robishaw JD | Direct interaction of the alpha and gamma subunits of the G proteins. Purification and analysis by limited proteolysis. | 1994 | J. Biol. Chem. | pmid:8106401 |
| Ng LL et al. | 3-Hydroxy-3-methyl glutaryl coenzyme A reductase inhibition modulates vasopressin-stimulated Ca2+ responses in rat A10 vascular smooth muscle cells. | 1994 | Circ. Res. | pmid:8293556 |
| Preisig-Müller R et al. | Heat shock enhances the amount of prenylated Dnaj protein at membranes of glyoxysomes. | 1994 | Eur. J. Biochem. | pmid:8307022 |
| Sinensky M et al. | The processing pathway of prelamin A. | 1994 | J. Cell. Sci. | pmid:8175923 |
| Mancini J et al. | Mevalonic aciduria in 3 siblings: a new recognizable metabolic encephalopathy. | 1993 May-Jun | Pediatr. Neurol. | pmid:8352861 |
| Roullet JB et al. | Mevalonate availability and cardiovascular functions. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8265617 |
| Li G and Stahl PD | Post-translational processing and membrane association of the two early endosome-associated rab GTP-binding proteins (rab4 and rab5). | 1993 | Arch. Biochem. Biophys. | pmid:8346922 |
| Hoang VQ et al. | The regulation of bile acid synthesis in cultured hamster hepatocytes. | 1993 | Biochem. Soc. Trans. | pmid:8224434 |
| Schwartz CC et al. | Cholesterol kinetics in subjects with bile fistula. Positive relationship between size of the bile acid precursor pool and bile acid synthetic rate. | 1993 | J. Clin. Invest. | pmid:8450070 |
| Hoffmann GF et al. | Clinical and biochemical phenotype in 11 patients with mevalonic aciduria. | 1993 | Pediatrics | pmid:8386351 |
| Foster JM et al. | Biosynthesis of isoprenoid compounds in Schistosoma mansoni. | 1993 | Mol. Biochem. Parasitol. | pmid:8264731 |
| Horbach S et al. | Isoprenoid biosynthesis in bacteria: two different pathways? | 1993 | FEMS Microbiol. Lett. | pmid:8405922 |
| Corsini A et al. | Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase. | 1993 | Atherosclerosis | pmid:8216498 |
| De Cuyper I et al. | Determination of changes in serum lathosterol during treatment with simvastatin to evaluate the role of lathosterol as a parameter for whole body cholesterol synthesis. | 1993 | Clin. Chim. Acta | pmid:8306452 |
| Doyle JW et al. | Effects of growth factors on cell cycle arrest in dolichyl phosphate-depleted cultures. | 1993 | J. Cell. Physiol. | pmid:8468363 |
| Keller RK and Vilsaint F | Regulation of isoprenoid metabolism in rat liver: near constant chain lengths of dolichyl phosphate and ubiquinone are maintained during greatly altered rates of cholesterogenesis. | 1993 | Biochim. Biophys. Acta | pmid:8399346 |
| Vlahcevic ZR et al. | Role of newly synthesized cholesterol or its metabolites on the regulation of bile acid biosynthesis after short-term biliary diversion in the rat. | 1993 | Hepatology | pmid:8359807 |
| Farrell FX et al. | Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated. | 1993 | Biochem. J. | pmid:8424780 |
| Kocarek TA et al. | Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes. | 1993 | Toxicol. Appl. Pharmacol. | pmid:8511800 |
| Hokland BM et al. | Cyclic AMP stimulates efflux of intracellular sterol from cholesterol-loaded cells. | 1993 | J. Biol. Chem. | pmid:7503979 |
| O'Donnell MP et al. | Lovastatin inhibits proliferation of rat mesangial cells. | 1993 | J. Clin. Invest. | pmid:8423236 |
| Davies JE and Ng LL | Simvastatin and intracellular pH regulation by the Na+/H+ antiport of SV40-virus-transformed human MRC5 fibroblasts. | 1993 | Clin. Sci. | pmid:8392920 |
| Miura S et al. | Inhibition of protein prenylation by patulin. | 1993 | FEBS Lett. | pmid:8436232 |
| Li G et al. | Blockade of mevalonate production by lovastatin attenuates bombesin and vasopressin potentiation of nutrient-induced insulin secretion in HIT-T15 cells. Probable involvement of small GTP-binding proteins. | 1993 | Biochem. J. | pmid:8424783 |
| Swiezewska E et al. | Biosynthesis of ubiquinone and plastoquinone in the endoplasmic reticulum-Golgi membranes of spinach leaves. | 1993 | J. Biol. Chem. | pmid:8419349 |