| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hughes PE and Tove SB | Synthesis of alpha-tocopherolquinone by the rat and its reduction by mitochondria. | 1980 | J. Biol. Chem. | pmid:7391070 |
| Chang TY and Limanek JS | Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamster ovary cells. | 1980 | J. Biol. Chem. | pmid:6105157 |
| Erickson SK et al. | Rat liver acyl-coenzyme A:cholesterol acyltransferase: its regulation in vivo and some of its properties in vitro. | 1980 | J. Lipid Res. | pmid:7441061 |
| Bard M and Downing JF | Genetic and biochemical aspects of yeast sterol regulation involving 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1981 | J. Gen. Microbiol. | pmid:7033470 |
| Douglass TS et al. | The biosynthesis, absorption, and origin of cholesterol and plant sterols in the Florida land crab. | 1981 | J. Lipid Res. | pmid:7276755 |
| Feingold KR et al. | The effect of decreased plasma cholesterol concentration on circulatinga mevalonate metabolism in rats. | 1981 | J. Lipid Res. | pmid:7276756 |
| Hoffman PC et al. | Effect of oxygenated sterol compounds on human bone marrow granulocytic progenitor cells. | 1981 | Blood | pmid:7448408 |
| Schroepfer GJ | Sterol biosynthesis. | 1981 | Annu. Rev. Biochem. | pmid:7023367 |
| DeBold CR and Elwood JC | Mevalonic acid analogs as inhibitors of cholesterol biosynthesis. | 1981 | J Pharm Sci | pmid:6101142 |
| Middleton B et al. | The control of sterol synthesis during development of rabbit mammary gland. | 1981 | J. Biol. Chem. | pmid:7014559 |
| Swift IE and Milborrow BV | Stereochemistry of beta-, gamma-, and epsilon-ring formation in bacterial C50. | 1981 | J. Biol. Chem. | pmid:7028738 |
| Brunengraber H et al. | Urinary clearance and metabolism of mevalonate by the isolataed perfused rat kidney. | 1981 | J. Lipid Res. | pmid:7276751 |
| Ryan J et al. | Isolation and characterization of cells resistant to ML236B (compactin) with increased levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1981 | J. Biol. Chem. | pmid:7240242 |
| Hagler WM et al. | Biosynthesis of radiolabeled T-2 toxin by Fusarium tricinctum. | 1981 | Appl. Environ. Microbiol. | pmid:7235702 |
| Stange EF et al. | Influence of dietary cholesterol, saturated and unsaturated lipid on 3-hydroxy-3-methylglutaryl CoA reductase activity in rabbit intestine and liver. | 1981 | J. Lipid Res. | pmid:7217785 |
| Baker FC and Schooley DA | Biosynthesis of 3-hydroxy-3-methylglutaryl-CoA, 3-hydroxy-3-ethylglutaryl-CoA, mevalonate and homomevalonate by insect corpus allatum and mammalian hepatic tissues. | 1981 | Biochim. Biophys. Acta | pmid:6166327 |
| Swift IE and Milborrow BV | Stereochemistry of allene biosynthesis and the formation of the acetylenic carotenoid diadinoxanthin and peridinin (C37) from neoxanthin. | 1981 | Biochem. J. | pmid:7337715 |
| Ott DB and Lachance PA | Biochemical controls of liver cholesterol biosynthesis. | 1981 | Am. J. Clin. Nutr. | pmid:6170219 |
| Henze K et al. | The effect of hydrocortisone on cholesterol metabolism of cultured human skin fibroblasts. | 1981 | Biochim. Biophys. Acta | pmid:6118180 |
| Fears R | The contribution of the cholesterol biosynthetic pathway to intermediary metabolism and cell function. | 1981 | Biochem. J. | pmid:7039614 |
| Mitchell ED and Avigan J | Control of phosphorylation and decarboxylation of mevalonic acid and its metabolites in cultured human fibroblasts and in rat liver in vivo. | 1981 | J. Biol. Chem. | pmid:6263908 |
| Florén CH and Nilsson A | Effects of hypothyroidism and cholesterol feeding on the clearance of chylomicron remnants in vivo and by rat hepatocyte monolayers. | 1981 | Eur. J. Clin. Invest. | pmid:6783423 |
| Stange EF et al. | Regulation of 3-hydroxy-3-methylglutaryl-CoA reductase by endogenous sterol synthesis in cultured intestinal mucosa. | 1981 | Biochim. Biophys. Acta | pmid:7225401 |
| Humphries GM | Difference in the ability of compactin and oxidized cholesterol, both known inhibitors of cholesterol biosynthesis, to suppress in vitro immune responses. | 1981 | Cancer Res. | pmid:7260948 |
| Pullinger CR and Gibbons GF | Effects of oleate and compactin on the metabolism and secretion of cholesterol and cholesteryl ester by rat hepatocytes. | 1982 | Biochim. Biophys. Acta | pmid:6960928 |
| Arebalo RE et al. | In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: immunotitration of the enzyme after short-term mevalonate or cholesterol feeding. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6948302 |
| Schwartz CC et al. | Central role of high density lipoprotein in plasma free cholesterol metabolism. | 1982 | J. Clin. Invest. | pmid:6953075 |
| Parker TS et al. | Mevalonic acid in human plasma: relationship of concentration and circadian rhythm to cholesterol synthesis rates in man. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6953446 |
| Poznansky MJ and Czekanski S | Cholesterol movement between human skin fibroblasts and phosphatidylcholine vesicles. | 1982 | Biochim. Biophys. Acta | pmid:7059600 |
| Brady PS et al. | Evidence for an underestimation of the shunt pathway of mevalonate metabolism in slices of livers and kidneys from fasted rats and rats in diabetic ketosis. | 1982 | J. Lipid Res. | pmid:6819335 |
| Cohen DC et al. | Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in vascular endothelial cells. Separate sterol and non-sterol components. | 1982 | J. Biol. Chem. | pmid:7107647 |
| Wong TK and Lennarz WJ | The site of biosynthesis and intracellular deposition of dolichol in rat liver. | 1982 | J. Biol. Chem. | pmid:7076684 |
| Kopito RR et al. | Metabolism of plasma mevalonate in rats and humans. | 1982 | J. Lipid Res. | pmid:7097123 |
| Golper TA and Swartz SH | Impaired renal mevalonate metabolism in nephrotic syndrome: a stimulus for increased hepatic cholesterogenesis independent of GFR and hypoalbuminemia. | 1982 | Metab. Clin. Exp. | pmid:7078427 |
| Larson RA et al. | Neutrophils are required for the DNA synthetic response of human lymphocytes to mevalonic acid: evidence suggesting that a nonsterol product of mevalonate is involved. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6953445 |
| Schnitzer-Polokoff R et al. | Isolation and characterization of a mammalian cell mutant defective in 3-hydroxy-3-methylglutaryl coenzyme A synthase. | 1982 | J. Biol. Chem. | pmid:6118375 |
| Nes WD et al. | Metabolism of mevalonic acid to long chain fatty alcohols in an insect. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7181890 |
| Greenwood DR and Rees HH | Mechanism of hydroxylation at C-22 during the biosynthesis of ecdysteroids in the locust Schistocerca gregaria. | 1982 | Biochem. J. | pmid:7165737 |
| Kleist H et al. | Metabolism in the hypothermically perfused kidney: utilization of mevalonate in the human and in the dog kidney. | 1982 | Eur Surg Res | pmid:7117329 |
| Schwartz CC et al. | Multicompartmental analysis of cholesterol metabolism in man. Quantitative kinetic evaluation of precursor sources and turnover of high density lipoprotein cholesterol esters. | 1982 | J. Clin. Invest. | pmid:7119117 |
| Angelin B et al. | Hepatic cholesterol metabolism in obesity: activity of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1982 | J. Lipid Res. | pmid:7119574 |
| Kling D and Gamble W | Cholesterol biosynthesis in polychlorinated biphenyl-treated rats. | 1982 | Environ. Res. | pmid:6802634 |
| Brady PS et al. | The tracing of the pathway of mevalonate's metabolism to other than sterols. | 1982 | J. Biol. Chem. | pmid:6809755 |
| Ekström T et al. | Biosynthesis of dolichol and dolichylphosphate in rat hepatocytes in vivo. | 1982 | FEBS Lett. | pmid:7160467 |
| Sinensky M et al. | Analysis of regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in a somatic cell mutant auxotrophic for mevalonate. | 1982 | J. Biol. Chem. | pmid:7085625 |
| Masuda A et al. | Chinese hamster cell mutant resistant to ML236B (Compactin) is defective in endocytosis of low-density lipo-protein. | 1982 | Mol. Cell. Biol. | pmid:7162516 |
| Pratt HP | Preimplantation mouse embryos synthesize membrane sterols. | 1982 | Dev. Biol. | pmid:7054002 |
| Lovati MR et al. | Cholesterol and bile-acid metabolism in normal and cholesterol-fed rabbits after partial ileal bypass. | 1982 | Exp. Mol. Pathol. | pmid:7140933 |
| Perkins SL et al. | Linkage of the isoprenoid biosynthetic pathway with induction of DNA synthesis in mouse lymphocytes. Effects of compactin on mitogen-induced lymphocytes in serum-free medium. | 1982 | Biochim. Biophys. Acta | pmid:6279167 |
| Tilvis R et al. | Metabolism of squalene in human fat cells. Demonstration of a two-pool system. | 1982 | J. Biol. Chem. | pmid:7107606 |
| Schmidt RA et al. | A study of the Influence of mevalonic acid and its metabolites on the morphology of swiss 3T3 cells. | 1982 | J. Cell Biol. | pmid:7142283 |
| Sablé-Amplis R and Sicart R | Evidence for negative feedback control of cholesterogenesis from mevalonate in liver: absence in the intestine of guinea pigs fed a 0.5% cholesterol diet. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7181883 |
| Volpe JJ and Obert KA | Interrelationships of ubiquinone and sterol syntheses in cultured cells of neural origin. | 1982 | J. Neurochem. | pmid:7062041 |
| Wilson WK et al. | Determination of the enantiomeric purity of mevalonolactone via NMR using a chiral lanthanide shift reagent. | 1982 | J. Lipid Res. | pmid:7097129 |
| Ranganathan S et al. | Effect of pantethine on the biosynthesis of cholesterol in human skin fibroblasts. | 1982 | Atherosclerosis | pmid:7150392 |
| Maxwell RE et al. | Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats. | 1983 | Atherosclerosis | pmid:6579963 |
| Simpkins C | Thyroid hormone in biological rhythms. | 1983 | Med. Hypotheses | pmid:6318057 |
| Davis RA et al. | Bile acid synthesis by cultured hepatocytes. Inhibition by mevinolin, but not by bile acids. | 1983 | J. Biol. Chem. | pmid:6550600 |
| Suckling KE et al. | In vivo modulation of rat liver acyl-coenzyme A:cholesterol acyltransferase by phosphorylation and substrate supply. | 1983 | FEBS Lett. | pmid:6873300 |
| Surani MA et al. | Mevalonate reverses the developmental arrest of preimplantation mouse embryos by Compactin, an inhibitor of HMG Co A reductase. | 1983 | J Embryol Exp Morphol | pmid:6886611 |
| Fliesler SJ and Schroepfer GJ | Metabolism of mevalonic acid in cell-free homogenates of bovine retinas. Formation of novel isoprenoid acids. | 1983 | J. Biol. Chem. | pmid:6654904 |
| Wilton DC | The effect of cholesterol on ubiquinone and tetrahymanol biosynthesis in Tetrahymena pyriformis. | 1983 | Biochem. J. | pmid:6418144 |
| Takii Y et al. | Arrest of 3T3 cells in G1 phase by low density lipoprotein. | 1983 | Cell Struct. Funct. | pmid:6671216 |
| Sprott GD et al. | Isolation and chemical composition of the cytoplasmic membrane of the archaebacterium Methanospirillum hungatei. | 1983 | J. Biol. Chem. | pmid:6833242 |
| Goodwin TW | Developments in carotenoid biochemistry over 40 years. The third Morton lecture. | 1983 | Biochem. Soc. Trans. | pmid:6642057 |
| Colannino NM and Lipke H | Increased deposition of cholesterol in brain after electroconvulsive seizure. | 1983 | Epilepsia | pmid:6617590 |
| Larson RA et al. | Neutrophil-assisted DNA synthesis by human lymphocytes in response to mevalonic acid; enhancement by cytochalasin B. | 1983 | Cell. Immunol. | pmid:6640672 |
| Krieger M | The use of amphotericin B to detect inhibitors of cellular cholesterol biosynthesis. | 1983 | Anal. Biochem. | pmid:6559041 |
| Quesney-Huneeus V et al. | The dual role of mevalonate in the cell cycle. | 1983 | J. Biol. Chem. | pmid:6848509 |
| Brady PS et al. | Effects of estrogen and testosterone on the metabolism of mevalonate by the shunt pathway. | 1983 | J. Lipid Res. | pmid:6415196 |
| Gavigan SJ and Knight BL | The effects of low-density lipoprotein and cholesterol on acyl-coenzyme A: cholesterol acyltransferase activity in membranes from cultured human fibroblasts. | 1983 | Biochem. J. | pmid:6651782 |
| Yachnin S et al. | Increased cholesterol biosynthesis in leukemic cells from patients with hairy cell leukemia. | 1983 | Blood | pmid:6600213 |
| Melnykovych G and Clowes KK | Suppression of glucocorticoid-induced elevation of alkaline phosphatase in C-4-1 cells by inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and reversal of the suppression by mevalonate. | 1983 | Biochim. Biophys. Acta | pmid:6830849 |
| Edwards PA et al. | Mevalonolactone inhibits the rate of synthesis and enhances the rate of degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in rat hepatocytes. | 1983 | J. Biol. Chem. | pmid:6863245 |
| Hoffman PC et al. | Cholesterol and mevalonic acid are independent requirements for the in vitro proliferation of human bone marrow granulocyte progenitor cells: studies using ML-236B. | 1983 | Blood | pmid:6831033 |
| Field FJ and Mathur SN | Regulation of acyl CoA:cholesterol acyltransferase by 25-hydroxycholesterol in rabbit intestinal microsomes and absorptive cells. | 1983 | J. Lipid Res. | pmid:6631233 |
| Dull BJ et al. | The modulating effect of an inhibitor of cholesterolgenesis present in bovine milk upon the synthesis of cholesterol, dolichol and ubiquinone. | 1983 | Atherosclerosis | pmid:6661267 |
| Thompson JS et al. | Morphologic and biochemical changes in dogs after portacaval shunt plus bile fistula or ileal bypass: failure of bile fistula or ileal bypass to prevent hepatocyte atrophy. | 1983 Jul-Aug | Hepatology | pmid:6862371 |
| Aguilera JA et al. | Postnatal development of the sterol and nonsterol mevalonate metabolism in chick liver and kidneys. Effect of cholesterol feeding. | 1984 | Ann. Nutr. Metab. | pmid:6517527 |
| Beale JM et al. | Studies on the biosynthesis of terrecyclic acid A, an antitumor antibiotic from Aspergillus terreus. | 1984 | J. Antibiot. | pmid:6511664 |
| Gill JF et al. | Transport of mevalonate by Pseudomonas sp. strain M. | 1984 | J. Bacteriol. | pmid:6434521 |
| Schmidt RA et al. | Evidence for post-translational incorporation of a product of mevalonic acid into Swiss 3T3 cell proteins. | 1984 | J. Biol. Chem. | pmid:6565705 |
| Ekström TJ et al. | Metabolic labeling of dolichol and dolichyl phosphate in isolate hepatocytes. | 1984 | J. Biol. Chem. | pmid:6469972 |
| Kopito RR et al. | The shunt pathway of mevalonate metabolism in the isolated perfused rat kidney. | 1984 | J. Biol. Chem. | pmid:6706942 |
| Harwood HJ et al. | Measurement of human leukocyte microsomal HMG-CoA reductase activity. | 1984 | J. Lipid Res. | pmid:6491541 |
| Bergstrom JD et al. | The regulation of acetoacetyl-CoA synthetase activity by modulators of cholesterol synthesis in vivo and the utilization of acetoacetate for cholesterogenesis. | 1984 | J. Biol. Chem. | pmid:6501306 |
| Parker TS et al. | Plasma mevalonate as a measure of cholesterol synthesis in man. | 1984 | J. Clin. Invest. | pmid:6565710 |
| Javitt NB et al. | Rapid synthesis of 26-hydroxycholesterol from mevalonic acid in the Syrian hamster. | 1984 | Biochim. Biophys. Acta | pmid:6733127 |
| Boissonneault GA and Heiniger HJ | 25-Hydroxycholesterol-induced elevation in 45Ca uptake: correlation with depressed DNA synthesis. | 1984 | J. Cell. Physiol. | pmid:6430918 |
| Ryder NS et al. | Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans. | 1984 | Antimicrob. Agents Chemother. | pmid:6375557 |
| Nakanishi S et al. | Preparation of 14C-labeled and unlabeled sterol intermediates from yeast using metabolic inhibitors. | 1984 | J. Biochem. | pmid:6397465 |
| Fairbanks KP et al. | Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor. | 1984 | J. Biol. Chem. | pmid:6693424 |
| Servouse M et al. | Isolation and characterization of yeast mutants blocked in mevalonic acid formation. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6148937 |
| Deneris ES et al. | In vitro biosynthesis of isoprene from mevalonate utilizing a rat liver cytosolic fraction. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6487307 |
| Wade DP et al. | Independent regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and chylomicron remnant receptor activities in rat liver. | 1984 | Biochem. J. | pmid:6324750 |
| Capuzzi DM and Cevallos WH | Inhibition of hepatic cholesterol and triglyceride synthesis by guanabenz acetate. | 1984 | J. Cardiovasc. Pharmacol. | pmid:6084138 |
| Clarke CF et al. | Diurnal rhythm of rat liver mRNAs encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase. Correlation of functional and total mRNA levels with enzyme activity and protein. | 1984 | J. Biol. Chem. | pmid:6540773 |
| Randolph RK et al. | Cholesterol metabolism in pigeon aortic smooth muscle cells lacking a functional low density lipoprotein receptor pathway. | 1984 | J. Lipid Res. | pmid:6491537 |
| Aguilera JA et al. | Effect of dietary cholesterol on mevalonate metabolism by sterol and nonsterol pathways. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6477574 |
| Beg ZH et al. | In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase, reductase kinase, and reductase kinase kinase by mevalonolactone. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6594693 |