| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Metz SA et al. | Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins. | 1993 | Biochem. J. | pmid:8216234 |
| Dahl NK et al. | Abnormal regulation of low density lipoprotein-sensitive events in a cholesterol transport mutant. | 1993 | J. Biol. Chem. | pmid:8349588 |
| Schwartz CC et al. | Cholesterol kinetics in subjects with bile fistula. Positive relationship between size of the bile acid precursor pool and bile acid synthetic rate. | 1993 | J. Clin. Invest. | pmid:8450070 |
| Jones MP et al. | Cholesterol 7 alpha-hydroxylase: evidence for transcriptional regulation by cholesterol or metabolic products of cholesterol in the rat. | 1993 | J. Lipid Res. | pmid:8354954 |
| Rilling HC et al. | Differential prenylation of proteins as a function of mevalonate concentration in CHO cells. | 1993 | Arch. Biochem. Biophys. | pmid:8460935 |
| Seo S et al. | Effect of sterol biosynthesis inhibitor, SSF-109, on cholesterol synthesis in isolated rat hepatocytes. | 1993 | Steroids | pmid:8484187 |
| De Cuyper I et al. | Determination of changes in serum lathosterol during treatment with simvastatin to evaluate the role of lathosterol as a parameter for whole body cholesterol synthesis. | 1993 | Clin. Chim. Acta | pmid:8306452 |
| McCaskill D and Croteau R | Procedures for the isolation and quantification of the intermediates of the mevalonic acid pathway. | 1993 | Anal. Biochem. | pmid:8297005 |
| Parker RA et al. | Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1993 | J. Biol. Chem. | pmid:8388388 |
| Mellon SH and Deschepper CF | Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain. | 1993 | Brain Res. | pmid:8111631 |
| Komori A et al. | Canventol inhibits tumor promotion in CD-1 mouse skin through inhibition of tumor necrosis factor alpha release and of protein isoprenylation. | 1993 | Cancer Res. | pmid:8339247 |
| Cox AD et al. | The carboxyl-terminal CXXX sequence of Gi alpha, but not Rab5 or Rab11, supports Ras processing and transforming activity. | 1993 | J. Biol. Chem. | pmid:8505289 |
| Rohmer M et al. | Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. | 1993 | Biochem. J. | pmid:8240251 |
| Giroux LM et al. | Simvastatin inhibits the oxidation of low-density lipoproteins by activated human monocyte-derived macrophages. | 1993 | Biochim. Biophys. Acta | pmid:8380338 |
| Bernini F et al. | Requirement for mevalonate in acetylated LDL induction of cholesterol esterification in macrophages. | 1993 | Atherosclerosis | pmid:8141843 |
| Arellano R and Grinstein S | Role of isoprenylation in intracellular pH regulation of granulocytes. | 1993 | FEBS Lett. | pmid:8405466 |
| Randall SK et al. | Protein isoprenylation in suspension-cultured tobacco cells. | 1993 | Plant Cell | pmid:8485402 |
| Miura S et al. | Inhibition of protein prenylation by patulin. | 1993 | FEBS Lett. | pmid:8436232 |
| Silber JR et al. | The effect of mevalonic acid deprivation on enzymes of DNA replication in cells emerging from quiescence. | 1992 | Biochem. J. | pmid:1281982 |
| Larsson O and Wejde J | Dolichol delays G1-arrest for one cell cycle in human fibroblasts subjected to depletion of serum or mevalonate. | 1992 | J. Cell. Sci. | pmid:1487489 |
| Roitelman J and Simoni RD | Distinct sterol and nonsterol signals for the regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase. | 1992 | J. Biol. Chem. | pmid:1460026 |
| Kim CM et al. | cDNA cloning of MEV, a mutant protein that facilitates cellular uptake of mevalonate, and identification of the point mutation responsible for its gain of function. | 1992 | J. Biol. Chem. | pmid:1429658 |
| Overmeyer JH and Maltese WA | Isoprenoid requirement for intracellular transport and processing of murine leukemia virus envelope protein. | 1992 | J. Biol. Chem. | pmid:1429616 |
| Adamson P et al. | Post-translational modifications of p21rho proteins. | 1992 | J. Biol. Chem. | pmid:1400319 |
| Mikulski SM et al. | Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines. | 1992 | Br. J. Cancer | pmid:1503903 |
| Peter M et al. | Isoprenylation of rab proteins on structurally distinct cysteine motifs. | 1992 | J. Cell. Sci. | pmid:1429897 |
| Newman CM et al. | Post-translational processing of Schizosaccharomyces pombe YPT proteins. | 1992 | J. Biol. Chem. | pmid:1597466 |
| Graber SG et al. | Expression of functional G protein beta gamma dimers of defined subunit composition using a baculovirus expression system. | 1992 | J. Biol. Chem. | pmid:1618813 |
| Schafer BL et al. | Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria. | 1992 | J. Biol. Chem. | pmid:1377680 |
| Pronin AN and Gautam N | Interaction between G-protein beta and gamma subunit types is selective. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631113 |
| Khosravi-Far R et al. | Protein prenylation: key to ras function and cancer intervention? | 1992 | Cell Growth Differ. | pmid:1419908 |
| Havel CM and Watson JA | Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute, basal mevalonate synthesis rate determination. | 1992 | Arch. Biochem. Biophys. | pmid:1567218 |
| Kinsella BT and Maltese WA | rab GTP-binding proteins with three different carboxyl-terminal cysteine motifs are modified in vivo by 20-carbon isoprenoids. | 1992 | J. Biol. Chem. | pmid:1740442 |
| Bradfute DL et al. | Squalene synthase-deficient mutant of Chinese hamster ovary cells. | 1992 | J. Biol. Chem. | pmid:1526971 |
| Giannakouros T et al. | Protein prenylation in Schizosaccharomyces pombe. | 1992 | FEBS Lett. | pmid:1551414 |
| Inglese J et al. | Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase. | 1992 | J. Biol. Chem. | pmid:1730692 |
| Manzi P et al. | Seasonal commitment of HMGCoA reductase activity to vitellogenin production. | 1992 | Biosci. Rep. | pmid:1391685 |
| Schulz S et al. | Mechanisms of cell growth inhibition and cell cycle arrest in human colonic adenocarcinoma cells by dehydroepiandrosterone: role of isoprenoid biosynthesis. | 1992 | Cancer Res. | pmid:1531325 |
| Bell FP et al. | L-carnitine administration and withdrawal affect plasma and hepatic carnitine concentrations, plasma lipid and lipoprotein composition, and in vitro hepatic lipogenesis from labeled mevalonate and oleate in normal rabbits. | 1992 | J. Nutr. | pmid:1552371 |
| Bejarano ER and Cerdá-Olmedo E | Independence of the carotene and sterol pathways of Phycomyces. | 1992 | FEBS Lett. | pmid:1633878 |
| Sawamura M et al. | Liver mevalonate 5-pyrophosphate decarboxylase is responsible for reduced serum cholesterol in stroke-prone spontaneously hypertensive rat. | 1992 | J. Biol. Chem. | pmid:1556116 |
| Stone BG and Evans CD | Evidence for a common biliary cholesterol and VLDL cholesterol precursor pool in rat liver. | 1992 | J. Lipid Res. | pmid:1464750 |
| Lutz RJ et al. | Feedback inhibition of polyisoprenyl pyrophosphate synthesis from mevalonate in vitro. Implications for protein prenylation. | 1992 | J. Biol. Chem. | pmid:1569056 |
| Meigs TE and Simoni RD | Regulated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in permeabilized cells. | 1992 | J. Biol. Chem. | pmid:1618856 |
| Sinensky M and Lutz RJ | The prenylation of proteins. | 1992 | Bioessays | pmid:1546978 |
| Anant JS and Fung BK | In vivo farnesylation of rat rhodopsin kinase. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1550556 |
| Kasim SE et al. | Mechanisms of triglyceride-lowering effect of an HMG-CoA reductase inhibitor in a hypertriglyceridemic animal model, the Zucker obese rat. | 1992 | J. Lipid Res. | pmid:1552226 |
| Buchwald H | Cholesterol inhibition, cancer, and chemotherapy. | 1992 | Lancet | pmid:1349377 |
| Fenton RG et al. | Regulation of intracellular actin polymerization by prenylated cellular proteins. | 1992 | J. Cell Biol. | pmid:1560030 |
| Khosravi-Far R et al. | Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct. | 1992 | J. Biol. Chem. | pmid:1332953 |
| van Heusden GP et al. | Increased cholesterol synthesis in Chinese hamster ovary cells deficient in peroxisomes. | 1992 | Biochim. Biophys. Acta | pmid:1606178 |
| Reimann FM et al. | Regulation of cholesterol metabolism and low-density lipoprotein binding in human intestinal Caco-2 cells. | 1992 | Digestion | pmid:1639221 |
| Bokoch GM and Prossnitz V | Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells. | 1992 | J. Clin. Invest. | pmid:1310693 |
| Sunazuka T et al. | Synthesis of 1233A analogs and their inhibitory activity against hydroxymethylglutaryl coenzyme A synthase. | 1992 | J. Antibiot. | pmid:1355474 |
| Harada-Shiba M et al. | Siblings with normal LDL receptor activity and severe hypercholesterolemia. | 1992 | Arterioscler. Thromb. | pmid:1525122 |
| Henry A et al. | Fibric acid derivatives: effects on the synthesis of isoprenoid lipids in cultured human lymphocytes. | 1992 | Biochim. Biophys. Acta | pmid:1643103 |
| Qin W et al. | Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytes. | 1992 | Biochim. Biophys. Acta | pmid:1627634 |
| Dahl NK et al. | Isolation and characterization of Chinese hamster ovary cells defective in the intracellular metabolism of low density lipoprotein-derived cholesterol. | 1992 | J. Biol. Chem. | pmid:1537866 |
| Cenedella RJ et al. | Cholesterylene, a newly recognized tissue lipid, found at high levels in the cornea. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1510688 |
| Chun KT and Simoni RD | The role of the membrane domain in the regulated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1992 | J. Biol. Chem. | pmid:1740463 |
| Casey WM et al. | Regulation of partitioned sterol biosynthesis in Saccharomyces cerevisiae. | 1992 | J. Bacteriol. | pmid:1429452 |
| Pandak WM et al. | Bile acid synthesis. VI. Regulation of cholesterol 7 alpha-hydroxylase by taurocholate and mevalonate. | 1992 | J. Lipid Res. | pmid:1619360 |
| Boyle PJ et al. | Role of GH in regulating nocturnal rates of lipolysis and plasma mevalonate levels in normal and diabetic humans. | 1992 | Am. J. Physiol. | pmid:1636694 |
| Jones PJ et al. | Correspondence between plasma mevalonic acid levels and deuterium uptake in measuring human cholesterol synthesis. | 1992 | Eur. J. Clin. Invest. | pmid:1459177 |
| Ellsworth JL et al. | Evidence for sterol-independent regulation of low-density lipoprotein receptor activity in Hep-G2 cells. | 1991 | Biochem. J. | pmid:1930137 |
| Epstein WW et al. | Quantitation of prenylcysteines by a selective cleavage reaction. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1946384 |
| Löw P et al. | The mevalonate pathway in the bloodstream form of Trypanosoma brucei. Identification of dolichols containing 11 and 12 isoprene residues. | 1991 | J. Biol. Chem. | pmid:1918042 |
| Henry A et al. | Dolichol biosynthesis in human malignant cells. | 1991 | Biochem. J. | pmid:1654890 |
| Roitelman J et al. | Involvement of calcium in the mevalonate-accelerated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase. | 1991 | J. Biol. Chem. | pmid:1908464 |
| Mizuno T et al. | A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1907371 |
| Scoppola A et al. | Quantitation of plasma mevalonic acid using gas chromatography-electron capture mass spectrometry. | 1991 | J. Lipid Res. | pmid:1940620 |
| Faust JR and Dice JF | Evidence for isopentenyladenine modification on a cell cycle-regulated protein. | 1991 | J. Biol. Chem. | pmid:2033083 |
| Jakóbisiak M et al. | Cell cycle-specific effects of lovastatin. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1673788 |
| Kitten GT and Nigg EA | The CaaX motif is required for isoprenylation, carboxyl methylation, and nuclear membrane association of lamin B2. | 1991 | J. Cell Biol. | pmid:2007618 |
| Fujiyama A et al. | S-farnesylation and methyl esterification of C-terminal domain of yeast RAS2 protein prior to fatty acid acylation. | 1991 | J. Biol. Chem. | pmid:1917931 |
| Keung WM | Human liver alcohol dehydrogenases catalyze the oxidation of the intermediary alcohols of the shunt pathway of mevalonate metabolism. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1993065 |
| Schulz S and Nyce JW | Inhibition of protein isoprenylation and p21ras membrane association by dehydroepiandrosterone in human colonic adenocarcinoma cells in vitro. | 1991 | Cancer Res. | pmid:1835900 |
| Kwong LK et al. | Intestinal and hepatic cholesterogenesis in hypercholesterolemic dyslipidemia of experimental diabetes in dogs. | 1991 | Diabetes | pmid:1756903 |
| Hashimoto F and Hayashi H | Identification of intermediates after inhibition of cholesterol synthesis by aminotriazole treatment in vivo. | 1991 | Biochim. Biophys. Acta | pmid:1954238 |
| Hidaka Y et al. | Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells. | 1991 | J. Biol. Chem. | pmid:1649182 |
| Ong KK et al. | Assay of 3-hydroxy-3-methylglutaryl CoA reductase activity using anionic-exchange column chromatography. | 1991 | Anal. Biochem. | pmid:1776669 |
| Ness GC et al. | Feedback regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol is not due to altered mRNA levels. | 1991 | J. Biol. Chem. | pmid:1869523 |
| Shimizu S et al. | Possible involvement of 3-hydroxymethylglutaryl-CoA reductase in determining the side-chain length of ubiquinone in rat heart. | 1991 | Arch. Biochem. Biophys. | pmid:1846516 |
| Braun PE et al. | Isoprenoid modification permits 2',3'-cyclic nucleotide 3'-phosphodiesterase to bind to membranes. | 1991 | J. Neurosci. Res. | pmid:1666129 |
| Sanford J et al. | Gamma-subunits of G proteins, but not their alpha- or beta-subunits, are polyisoprenylated. Studies on post-translational modifications using in vitro translation with rabbit reticulocyte lysates. | 1991 | J. Biol. Chem. | pmid:1903391 |
| Farnsworth CC et al. | C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1906176 |
| Lindemann CJ et al. | Determination of mevalonolactone in capsules by capillary gas-liquid chromatography. | 1991 | J Pharm Biomed Anal | pmid:1911983 |
| Kinsella BT et al. | Posttranslational modification of Ha-ras p21 by farnesyl versus geranylgeranyl isoprenoids is determined by the COOH-terminal amino acid. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1924354 |
| Elmberger PG et al. | Effects of pravastatin and cholestyramine on products of the mevalonate pathway in familial hypercholesterolemia. | 1991 | J. Lipid Res. | pmid:1940625 |
| Khosravi-Far R et al. | Isoprenoid modification of rab proteins terminating in CC or CXC motifs. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1648736 |
| Chakrabarti R and Engleman EG | Interrelationships between mevalonate metabolism and the mitogenic signaling pathway in T lymphocyte proliferation. | 1991 | J. Biol. Chem. | pmid:1712015 |
| Mayer RJ et al. | Effects of a novel lanosterol 14 alpha-demethylase inhibitor on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in Hep G2 cells. | 1991 | J. Biol. Chem. | pmid:1657912 |
| Thelin A et al. | Covalent binding of dolichyl phosphate to proteins in rat liver. | 1991 | Eur. J. Biochem. | pmid:1999193 |
| Deanin GG et al. | Role of isoprenoid metabolism in IgE receptor-mediated signal transduction. | 1991 | J. Immunol. | pmid:1827487 |
| Kreuzer J et al. | Chemotaxis of the monocyte cell line U937: dependence on cholesterol and early mevalonate pathway products. | 1991 | Atherosclerosis | pmid:1759991 |
| Cuthbert JA and Lipsky PE | Negative regulation of cell proliferation by mevalonate or one of the mevalonate phosphates. | 1991 | J. Biol. Chem. | pmid:1917936 |
| Ng LL and Davies JE | HMG CoA reductase inhibitors affect Na(+)-H+ antiport activity in human lymphoblasts. | 1991 | Am. J. Physiol. | pmid:1659206 |
| Sepp-Lorenzino L et al. | Cell-cycle-dependent, differential prenylation of proteins. | 1991 | Eur. J. Biochem. | pmid:1889420 |
| Shoff SM et al. | Concentration-dependent increase of murine P388 and B16 population doubling time by the acyclic monoterpene geraniol. | 1991 | Cancer Res. | pmid:1988098 |
| Vögeli U and Chappell J | Inhibition of a plant sesquiterpene cyclase by mevinolin. | 1991 | Arch. Biochem. Biophys. | pmid:1898013 |