| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:8025334 | ||||
| Giron MD et al. | Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8022795 |
| Correll CC et al. | Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1994 | J. Biol. Chem. | pmid:8021239 |
| Gebhardt R et al. | Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells. | 1994 | Biochim. Biophys. Acta | pmid:8011681 |
| Hiser L et al. | ERG10 from Saccharomyces cerevisiae encodes acetoacetyl-CoA thiolase. | 1994 | J. Biol. Chem. | pmid:7989303 |
| Sinensky M et al. | Expression of prelamin A but not mature lamin A confers sensitivity of DNA biosynthesis to lovastatin on F9 teratocarcinoma cells. | 1994 | J. Cell. Sci. | pmid:7983180 |
| Mallat A et al. | Effect of simvastatin, an inhibitor of hydroxy-methylglutaryl coenzyme A reductase, on the growth of human Ito cells. | 1994 | Hepatology | pmid:7982659 |
| Hrab RV et al. | Prevention of fluvastatin-induced toxicity, mortality, and cardiac myopathy in pregnant rats by mevalonic acid supplementation. | 1994 | Teratology | pmid:7974251 |
| Ortiz JA et al. | Transfection of the ketogenic mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase cDNA into Mev-1 cells corrects their auxotrophy for mevalonate. | 1994 | J. Biol. Chem. | pmid:7961793 |
| Russell-Jones DL et al. | The effect of growth hormone replacement on serum lipids, lipoproteins, apolipoproteins and cholesterol precursors in adult growth hormone deficient patients. | 1994 | Clin. Endocrinol. (Oxf) | pmid:7955441 |
| Dimster-Denk D et al. | Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiae. | 1994 | Mol. Biol. Cell | pmid:7949422 |
| pmid:7935024 | ||||
| pmid:7926659 | ||||
| Ness GC et al. | Effect of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7 alpha hydroxylase. | 1994 | Arch. Biochem. Biophys. | pmid:7911291 |
| Camp LA and Hofmann SL | Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras. | 1993 | J. Biol. Chem. | pmid:7901201 |
| Johnson KA et al. | In vivo formation of 25-hydroxycholesterol from endogenous cholesterol after a single meal, dietary cholesterol challenge. | 1994 | J. Lipid Res. | pmid:7897321 |
| Herold G et al. | Influence of cholesterol supply on cell growth and differentiation in cultured enterocytes (CaCo-2). | 1995 | Digestion | pmid:7895934 |
| Pérez-Sala D et al. | Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease. | 1995 | J. Biol. Chem. | pmid:7890761 |
| Chiloeches A et al. | Effects of lovastatin on adenylyl cyclase activity and G proteins in GH4C1 cells. | 1995 | FEBS Lett. | pmid:7890038 |
| Munro E et al. | Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis. | 1994 | Eur. J. Clin. Invest. | pmid:7890015 |
| Masters BA et al. | In vitro myotoxicity of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, pravastatin, lovastatin, and simvastatin, using neonatal rat skeletal myocytes. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7878672 |
| pmid:7876919 | ||||
| Straka MS and Panini SR | Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate. | 1995 | Arch. Biochem. Biophys. | pmid:7872789 |
| Pfohl M et al. | Acute and chronic effects on cholesterol biosynthesis of LDL-apheresis with or without concomitant HMG-CoA reductase inhibitor therapy. | 1994 | J. Lipid Res. | pmid:7868973 |
| pmid:7851471 | ||||
| Soma MR et al. | In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin. | 1995 | Cancer Res. | pmid:7834630 |
| Shipton CA et al. | Isoprenylation of plant proteins in vivo. Isoprenylated proteins are abundant in the mitochondria and nuclei of spinach. | 1995 | J. Biol. Chem. | pmid:7822281 |
| Sekler MS and Simoni RD | Mutation in the lumenal part of the membrane domain of HMG-CoA reductase alters its regulated degradation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7818519 |
| Ortiz MB et al. | Mevalonate dependency of the early cell cycle mitogenic response to epidermal growth factor and prostaglandin F2 alpha in Swiss mouse 3T3 cells. | 1995 | J. Cell. Physiol. | pmid:7814446 |
| Cummings MH and Watts GF | Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in cholesteryl ester storage disease. | 1995 | Clin. Chem. | pmid:7813057 |
| Thelin A et al. | Effect of squalestatin 1 on the biosynthesis of the mevalonate pathway lipids. | 1994 | Biochim. Biophys. Acta | pmid:7811707 |
| Sagami H et al. | A novel type of protein modification by isoprenoid-derived materials. Diphytanylglycerylated proteins in Halobacteria. | 1995 | J. Biol. Chem. | pmid:7797461 |
| Schootemeijer A et al. | Relation between membrane fluidity and signal transduction in the human megakaryoblastic cell line MEG-01. | 1995 | Biochim. Biophys. Acta | pmid:7794941 |
| Crick DC et al. | Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7794274 |
| Corsini A et al. | Pharmacology of competitive inhibitors of HMG-CoA reductase. | 1995 | Pharmacol. Res. | pmid:7784310 |
| Re EB et al. | Co-expression of native and introduced genes reveals cryptic regulation of HMG CoA reductase expression in Arabidopsis. | 1995 | Plant J. | pmid:7773308 |
| Aspbury RA et al. | Lipid modification of signal-transducing polypeptides in the free-living nematode Caenorhabditis elegans. | 1995 | Biochem. Soc. Trans. | pmid:7758740 |
| Appelkvist EL et al. | Regulation of coenzyme Q biosynthesis. | 1994 | Mol. Aspects Med. | pmid:7752843 |
| Dimster-Denk D et al. | Control of RAS mRNA level by the mevalonate pathway. | 1995 | Mol. Biol. Cell | pmid:7749195 |
| Sasseville AM and Raymond Y | Lamin A precursor is localized to intranuclear foci. | 1995 | J. Cell. Sci. | pmid:7738105 |
| Massey LK et al. | Branched-chain amino acid catabolism in bacteria. | 1976 | Bacteriol Rev | pmid:773366 |
| Ishikawa S et al. | Simvastatin inhibits the cellular signaling and proliferative action of arginine vasopressin in cultured rat glomerular mesangial cells. | 1995 | Endocrinology | pmid:7720643 |
| Cummings MH et al. | Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in obesity: a stable isotope study. | 1995 | Clin. Sci. | pmid:7720348 |
| Cuthbert JA and Lipsky PE | Suppression of the proliferation of Ras-transformed cells by fluoromevalonate, an inhibitor of mevalonate metabolism. | 1995 | Cancer Res. | pmid:7712482 |
| Lala A et al. | The effects of insulin on plasma mevalonate concentrations in man. | 1994 | Ann. Nutr. Metab. | pmid:7710260 |
| pmid:7672316 | ||||
| Bernini F et al. | HMG-CoA reductase inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7670949 |
| Doerner KC et al. | Regulation of cholesterol 7 alpha-hydroxylase expression by sterols in primary rat hepatocyte cultures. | 1995 | J. Lipid Res. | pmid:7665995 |
| Inglese J | Prenylation-dependent targeting of G-protein-coupled receptor kinases. | 1995 | Meth. Enzymol. | pmid:7651147 |
| pmid:7651146 | ||||
| Cox AD | Mutation and analysis of prenylation signal sequences. | 1995 | Meth. Enzymol. | pmid:7651143 |
| Burton PM et al. | Azalanstat (RS-21607), a lanosterol 14 alpha-demethylase inhibitor with cholesterol-lowering activity. | 1995 | Biochem. Pharmacol. | pmid:7646560 |
| Crick DC et al. | Selective inhibition of cholesterol biosynthesis in brain cells by squalestatin 1. | 1995 | J. Neurochem. | pmid:7643114 |
| Meigs TE et al. | Farnesyl acetate, a derivative of an isoprenoid of the mevalonate pathway, inhibits DNA replication in hamster and human cells. | 1995 | Exp. Cell Res. | pmid:7641798 |
| Watts GF et al. | Direct correlation between cholesterol synthesis and hepatic secretion of apolipoprotein B-100 in normolipidemic subjects. | 1995 | Metab. Clin. Exp. | pmid:7637647 |
| Schroeder WA and Johnson EA | Singlet oxygen and peroxyl radicals regulate carotenoid biosynthesis in Phaffia rhodozyma. | 1995 | J. Biol. Chem. | pmid:7629161 |
| Kwiterovich PO and Motevalli M | Inhibition of protein tyrosine kinase alters the effect of serum basic protein I on triacylglycerols and cholesterol differently in normal and hyperapoB fibroblasts. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7627714 |
| Wiley MH et al. | Sex differences in the sterol and nonsterol metabolism of mevalonate. | 1979 | J. Biol. Chem. | pmid:762097 |
| Schedin S et al. | Changes in the levels of dolichol and dolichyl phosphate in a murine model of Niemann-Pick's type C disease. | 1995 | J. Neurochem. | pmid:7616223 |
| Roullet JB et al. | Mevalonate availability affects human and rat resistance vessel function. | 1995 | J. Clin. Invest. | pmid:7615793 |
| Dalton MB et al. | The farnesyl protein transferase inhibitor BZA-5B blocks farnesylation of nuclear lamins and p21ras but does not affect their function or localization. | 1995 | Cancer Res. | pmid:7614464 |
| Corsini A et al. | Pathogenesis of atherosclerosis and the role of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. | 1995 | Am. J. Cardiol. | pmid:7604791 |
| Rogler G et al. | Effects of fluvastatin on growth of porcine and human vascular smooth muscle cells in vitro. | 1995 | Am. J. Cardiol. | pmid:7604784 |
| Ranganathan G and Mukkada AJ | Ubiquinone biosynthesis in Leishmania major promastigotes. | 1995 | Int. J. Parasitol. | pmid:7601585 |
| pmid:7589240 | ||||
| Gayen AK and Peffley DM | The length of 5'-untranslated leader sequences influences distribution of 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in polysomes: effects of lovastatin, oxysterols, and mevalonate. | 1995 | Arch. Biochem. Biophys. | pmid:7574724 |
| Lin Y et al. | Differences in propionate-induced inhibition of cholesterol and triacylglycerol synthesis between human and rat hepatocytes in primary culture. | 1995 | Br. J. Nutr. | pmid:7547837 |
| Hokland BM et al. | Cyclic AMP stimulates efflux of intracellular sterol from cholesterol-loaded cells. | 1993 | J. Biol. Chem. | pmid:7503979 |
| Latruffe N et al. | Stimulation of protein kinase C activity by compactin in vascular smooth muscle cells. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7503722 |
| Yu SG et al. | Geraniol, an inhibitor of mevalonate biosynthesis, suppresses the growth of hepatomas and melanomas transplanted to rats and mice. | 1995 | J. Nutr. | pmid:7472655 |
| Drevon CA et al. | Secretion of very low density lipoproteins enriched in cholesteryl esters by cultured rat hepatocytes during simulation of intracellular cholesterol esterification. | 1980 | J. Lipid Res. | pmid:7462802 |
| Duncan JL and Buckingham L | Resistance to streptolysin O in mammalian cells treated with oxygenated derivatives of cholesterol. Cholesterol content of resistant cells and recovery of streptolysin O sensitivity. | 1980 | Biochim. Biophys. Acta | pmid:7459354 |
| Hoffman PC et al. | Effect of oxygenated sterol compounds on human bone marrow granulocytic progenitor cells. | 1981 | Blood | pmid:7448408 |
| Subbiah MT | Incorporation of 14C-mevalonate into biliary cholesterol and bile acids by perfused rat liver: effect of plasma and individual lipoproteins. | 1980 | Steroids | pmid:7444999 |
| Erickson SK et al. | Rat liver acyl-coenzyme A:cholesterol acyltransferase: its regulation in vivo and some of its properties in vitro. | 1980 | J. Lipid Res. | pmid:7441061 |
| George R and Goldfarb S | Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Morris hepatoma 7800 after intravenous injection of mevalonic acid. | 1980 | Cancer Res. | pmid:7438103 |
| Ciavatti M et al. | Biosynthesis of cholesterol and cholesterol precursors in platelets of female rats treated with oral contraceptives. | 1980 | Biochim. Biophys. Acta | pmid:7437455 |
| Kritchevsky D et al. | Cholesterol synthesis in tissues of young and old Fisher 344 and Sprague-Dawley rats. | 1980 | Exp. Gerontol. | pmid:7428858 |
| Feingold KR et al. | Influence of thyroid hormone status on mevalonate metabolism in rats. | 1980 | J. Clin. Invest. | pmid:7419712 |
| Erickson SK et al. | Studies on the mechanisms of the rapid modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in intact liver by mevalonolactone and 25-hydroxycholesterol. | 1980 | Biochim. Biophys. Acta | pmid:7417482 |
| Turner JA and Prebble JN | Protection of cell viability and respiratory quinone levels by carotenoid in Micrococcus lysodeikticus (M. luteus). | 1980 | J. Gen. Microbiol. | pmid:7411117 |
| Curtiss LK and Edgington TS | Differences in the characteristics of inhibition of lymphocyte stimulation by 25-hydroxycholesterol and by the immunoregulatory serum lipoprotein LDL-In. | 1980 | J. Immunol. | pmid:7410845 |
| Drevon CA et al. | Regulation of cholesterol esterification and biosynthesis in monolayer cultures of normal adult rat hepatocytes. | 1980 | J. Biol. Chem. | pmid:7410416 |
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| Swift IE and Milborrow BV | Retention of the 4-pro-R hydrogen atom of mevalonate at C-2,2' of bacterioruberin in Halobacterium halobium. | 1980 | Biochem. J. | pmid:7406867 |
| Feingold KR et al. | Sex difference in human mevalonate metabolism. | 1980 | J. Clin. Invest. | pmid:7400320 |
| Hughes PE and Tove SB | Synthesis of alpha-tocopherolquinone by the rat and its reduction by mitochondria. | 1980 | J. Biol. Chem. | pmid:7391070 |
| Faust JR et al. | Synthesis of delta 2-isopentenyl tRNA from mevalonate in cultured human fibroblasts. | 1980 | J. Biol. Chem. | pmid:7391033 |
| Elliott JG and Lachance PA | Effects of vitamin A and ascorbic acid on in vitro cholesterol biosynthesis in the rat. | 1980 | J. Nutr. | pmid:7381607 |
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| Shao MJ and Lei KY | Conversion of [2-14C] mevalonate into cholesterol, lanosterol and squalene in copper-deficient rats. | 1980 | J. Nutr. | pmid:7373433 |
| Raulston DL et al. | Cycloheximide inhibits sterol biosynthesis in cell-free preparations of rat liver. | 1980 | J. Biol. Chem. | pmid:7372603 |
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