| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Morrone D et al. | Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19777230 |
| Fukunaga M et al. | Mast cell death induced by 24(S),25-epoxycholesterol. | 2010 | Exp. Cell Res. | pmid:20854813 |
| Honour JW | Steroid assays in paediatric endocrinology. | 2010 | J Clin Res Pediatr Endocrinol | pmid:21274330 |
| Head BP et al. | Loss of caveolin-1 accelerates neurodegeneration and aging. | 2010 | PLoS ONE | pmid:21203469 |
| Zheng Z et al. | Improvement of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial reactive oxygen species pathway mediated by peroxisome proliferator-activated receptor gamma coactivator 1alpha. | 2010 | Diabetes | pmid:20566666 |
| Liu Q et al. | Dynamics of lamin-A processing following precursor accumulation. | 2010 | PLoS ONE | pmid:20526372 |
| Aoyama T et al. | Pharmacokinetic/pharmacodynamic modeling and simulation of rosuvastatin using an extension of the indirect response model by incorporating a circadian rhythm. | 2010 | Biol. Pharm. Bull. | pmid:20522984 |
| Jameson JM et al. | A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes. | 2010 | Cell. Immunol. | pmid:20483407 |
| Hughes M et al. | Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP. | 2010 | J. Neurochem. | pmid:20477946 |
| Targett-Adams P et al. | Lipid metabolism and HCV infection. | 2010 | Viruses | pmid:21994676 |
| Snoeren TA et al. | The herbivore-induced plant volatile methyl salicylate negatively affects attraction of the parasitoid Diadegma semiclausum. | 2010 | J. Chem. Ecol. | pmid:20407809 |
| Lefurgy ST et al. | Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae. | 2010 | J. Biol. Chem. | pmid:20404339 |
| Clendening JW et al. | Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma. | 2010 | Blood | pmid:20360469 |
| Delang L et al. | Antiviral therapy for hepatitis C virus: beyond the standard of care. | 2010 | Viruses | pmid:21994657 |
| Yang Z et al. | Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. | 2010 | Int. J. Cancer | pmid:19626588 |
| De Leo L et al. | Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches. | 2010 | Pharmacol. Res. | pmid:20206266 |
| Tisch D and Schmoll M | Light regulation of metabolic pathways in fungi. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19915832 |
| Coscia M et al. | Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. | 2010 | J. Cell. Mol. Med. | pmid:19818098 |
| Kojima Y et al. | Pitavastatin decreases the expression of endothelial lipase both in vitro and in vivo. | 2010 | Cardiovasc. Res. | pmid:20045866 |
| Kones R | Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective. | 2010 | Drug Des Devel Ther | pmid:21267417 |
| Hooff GP et al. | Isoprenoids, small GTPases and Alzheimer's disease. | 2010 | Biochim. Biophys. Acta | pmid:20382260 |
| Mitrofan LM et al. | Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells. | 2010 | J. Biol. Chem. | pmid:19875454 |
| Rossi J et al. | Laminar shear stress prevents simvastatin-induced adhesion molecule expression in cytokine activated endothelial cells. | 2010 | Eur. J. Pharmacol. | pmid:20863785 |
| Kaneda T et al. | Statins inhibited erythropoietin-induced proliferation of rat vascular smooth muscle cells. | 2010 | Eur. J. Pharmacol. | pmid:20851116 |
| Kassan M et al. | In vitro antioxidant activity of pravastatin provides vascular protection. | 2010 | Eur. J. Pharmacol. | pmid:20044990 |
| Kocsis GF et al. | Expression of genes related to oxidative/nitrosative stress in mouse hearts: effect of preconditioning and cholesterol diet. | 2010 | Med. Sci. Monit. | pmid:20037483 |
| Endo A | A historical perspective on the discovery of statins. | 2010 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:20467214 |
| Clendening JW et al. | Dysregulation of the mevalonate pathway promotes transformation. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20696928 |
| Rico J et al. | Enhanced production of a plant monoterpene by overexpression of the 3-hydroxy-3-methylglutaryl coenzyme A reductase catalytic domain in Saccharomyces cerevisiae. | 2010 | Appl. Environ. Microbiol. | pmid:20675444 |
| Okamura E et al. | Unprecedented acetoacetyl-coenzyme A synthesizing enzyme of the thiolase superfamily involved in the mevalonate pathway. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20534558 |
| Chen CC et al. | Effect of pravastatin on ventricular arrhythmias in infarcted rats: role of connexin43. | 2010 | J. Appl. Physiol. | pmid:20466804 |
| Norman KL and Sarnow P | Modulation of hepatitis C virus RNA abundance and the isoprenoid biosynthesis pathway by microRNA miR-122 involves distinct mechanisms. | 2010 | J. Virol. | pmid:19846523 |
| Hooff GP et al. | Modulation of cholesterol, farnesylpyrophosphate, and geranylgeranylpyrophosphate in neuroblastoma SH-SY5Y-APP695 cells: impact on amyloid beta-protein production. | 2010 | Mol. Neurobiol. | pmid:20405344 |
| Jiang XS et al. | Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency. | 2010 | Mol. Cell Proteomics | pmid:20305089 |
| Woo IS et al. | Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells. | 2010 | Neurosci. Lett. | pmid:20298756 |
| Asadollahi MA et al. | Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae. | 2010 | Biotechnol. Bioeng. | pmid:20091767 |
| Lee SK et al. | Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20043868 |
| Huang M et al. | Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03. | 2010 | Plant Physiol. | pmid:20463089 |
| Rydgren T and Sandler S | The protective effect of simvastatin against low dose streptozotocin induced type 1 diabetes in mice is independent of inhibition of HMG-CoA reductase. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19150339 |
| Yoon HE and Yang CW | Established and newly proposed mechanisms of chronic cyclosporine nephropathy. | 2009 | Korean J. Intern. Med. | pmid:19543484 |
| Jauhiainen M et al. | Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19665949 |
| Anthony JR et al. | Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene. | 2009 | Metab. Eng. | pmid:18775787 |
| Lorenzen W et al. | Isoprenoids are essential for fruiting body formation in Myxococcus xanthus. | 2009 | J. Bacteriol. | pmid:19617362 |
| Zhao S et al. | Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones. | 2009 | Bioorg. Med. Chem. | pmid:19879766 |
| Domoki F et al. | Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons. | 2009 | Am. J. Physiol., Cell Physiol. | pmid:18971391 |
| Xu Q et al. | Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant. | 2009 | BMC Genomics | pmid:19922663 |
| Rothwell C et al. | Cholesterol biosynthesis modulation regulates dengue viral replication. | 2009 | Virology | pmid:19419745 |
| Ledezma E et al. | Potentiated cytotoxic effects of statins and ajoene in murine melanoma cells. | 2009 | Melanoma Res. | pmid:19276863 |
| Maeda T and Horiuchi N | Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation. | 2009 | J. Biochem. | pmid:19254925 |
| Dje N'Guessan P et al. | Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. | 2009 | Arterioscler. Thromb. Vasc. Biol. | pmid:19122173 |
| Iriti M and Faoro F | Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. | 2009 | Int J Mol Sci | pmid:20111684 |
| Jawaid S et al. | Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). | 2009 | PLoS ONE | pmid:20011597 |
| Raemer PC et al. | Statins inhibit NK-cell cytotoxicity by interfering with LFA-1-mediated conjugate formation. | 2009 | Eur. J. Immunol. | pmid:19424968 |
| Chang PK et al. | Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae. | 2009 | Toxins (Basel) | pmid:22069533 |
| Kirmizis D and Chatzidimitriou D | Pleiotropic vasoprotective effects of statins: the chicken or the egg? | 2009 | Drug Des Devel Ther | pmid:19920934 |
| Eldor R and Raz I | American Diabetes Association indications for statins in diabetes: is there evidence? | 2009 | Diabetes Care | pmid:19875586 |
| Massonnet B et al. | Pharmacological inhibitors of the mevalonate pathway activate pro-IL-1 processing and IL-1 release by human monocytes. | 2009 | Eur. Cytokine Netw. | pmid:19825520 |
| Wang W et al. | Global characterization of Artemisia annua glandular trichome transcriptome using 454 pyrosequencing. | 2009 | BMC Genomics | pmid:19818120 |
| Brahmachari S et al. | Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses. | 2009 | J. Immunol. | pmid:19812204 |
| de Souza W and Rodrigues JC | Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. | 2009 | Interdiscip Perspect Infect Dis | pmid:19680554 |
| Zeki AA et al. | Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond. | 2009 | Am. J. Respir. Crit. Care Med. | pmid:19608720 |
| Minichsdorfer C and Hohenegger M | Autocrine amplification loop in statin-induced apoptosis of human melanoma cells. | 2009 | Br. J. Pharmacol. | pmid:19563533 |
| Perttilä J et al. | OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism. | 2009 | J. Mol. Med. | pmid:19554302 |
| Montoya CJ et al. | Antiretroviral effect of lovastatin on HIV-1-infected individuals without highly active antiretroviral therapy (The LIVE study): a phase-II randomized clinical trial. | 2009 | Trials | pmid:19538732 |
| Li J et al. | Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells. | 2009 | J. Immunol. | pmid:19494338 |
| Suzuki M et al. | Complete blockage of the mevalonate pathway results in male gametophyte lethality. | 2009 | J. Exp. Bot. | pmid:19363204 |
| Balibar CJ et al. | The mevalonate pathway of Staphylococcus aureus. | 2009 | J. Bacteriol. | pmid:19028897 |
| Khan MA et al. | Statins impair CD1d-mediated antigen presentation through the inhibition of prenylation. | 2009 | J. Immunol. | pmid:19342651 |
| Alvarez Y et al. | Cyclooxygenase-2 induced by zymosan in human monocyte-derived dendritic cells shows high stability, and its expression is enhanced by atorvastatin. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19318593 |
| Niessen J et al. | Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin. | 2009 | Drug Metab. Dispos. | pmid:19237515 |
| Lachmann HJ and Hawkins PN | Developments in the scientific and clinical understanding of autoinflammatory disorders. | 2009 | Arthritis Res. Ther. | pmid:19232070 |
| Kim WY et al. | Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation. | 2009 | J. Neurochem. | pmid:19209406 |
| Zeiser R et al. | Regulation of different inflammatory diseases by impacting the mevalonate pathway. | 2009 | Immunology | pmid:19191903 |
| Yeger-Lotem E et al. | Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity. | 2009 | Nat. Genet. | pmid:19234470 |
| Knight LA et al. | Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay. | 2009 | BMC Cancer | pmid:19175937 |
| Deshpande G et al. | Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration. | 2009 | PLoS Genet. | pmid:19132091 |
| Mansouri H et al. | Effects of gibberellic acid on primary terpenoids and delta-tetrahydrocannabinol in Cannabis sativa at flowering stage. | 2009 | J Integr Plant Biol | pmid:19522814 |
| Monzack EL et al. | Efficacy of simvastatin treatment of valvular interstitial cells varies with the extracellular environment. | 2009 | Arterioscler. Thromb. Vasc. Biol. | pmid:19023089 |
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| Olson AL et al. | Substrate induced structural and dynamics changes in human phosphomevalonate kinase and implications for mechanism. | 2009 | Proteins | pmid:18798562 |
| Sillero MA et al. | Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts. | 2009 | Biochem. Pharmacol. | pmid:19414000 |
| Dueber JE et al. | Synthetic protein scaffolds provide modular control over metabolic flux. | 2009 | Nat. Biotechnol. | pmid:19648908 |
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| Tsuruta H et al. | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. | 2009 | PLoS ONE | pmid:19221601 |
| Fujimoto M et al. | Fluvastatin inhibits mast cell degranulation without changing the cytoplasmic Ca2+ level. | 2009 | Eur. J. Pharmacol. | pmid:19059394 |
| Sun X et al. | Identified biosynthetic pathway of aspergiolide A and a novel strategy to increase its production in a marine-derived fungus Aspergillus glaucus by feeding of biosynthetic precursors and inhibitors simultaneously. | 2009 | Bioresour. Technol. | pmid:19386490 |
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| Kroll J et al. | Establishment of a novel anabolism-based addiction system with an artificially introduced mevalonate pathway: complete stabilization of plasmids as universal application in white biotechnology. | 2009 | Metab. Eng. | pmid:19558962 |
| Alagna F et al. | Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development. | 2009 | BMC Genomics | pmid:19709400 |
| Wali VB et al. | Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment. | 2009 | Lipids | pmid:19777282 |
| Grigore L et al. | Combination therapy in cholesterol reduction: focus on ezetimibe and statins. | 2008 | Vasc Health Risk Manag | pmid:18561502 |
| Sharyo S et al. | Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway. | 2008 | Kidney Int. | pmid:18509318 |
| Okada K et al. | Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. | 2008 | Plant Cell Physiol. | pmid:18303110 |
| Matsuda T et al. | Simvastatin inhibits catecholamine secretion and synthesis induced by acetylcholine via blocking Na+ and Ca2+ influx in bovine adrenal medullary cells. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18593956 |
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