| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
Mevalonic acid
Mevalonic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Mevalonic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Mevalonic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Mevalonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ogunwobi OO and Beales IL | Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. | 2008 | Am. J. Gastroenterol. | pmid:18371146 |
| Kimura T et al. | Induction of scavenger receptor class B type I is critical for simvastatin enhancement of high-density lipoprotein-induced anti-inflammatory actions in endothelial cells. | 2008 | J. Immunol. | pmid:18981156 |
| Kotti T et al. | Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18685105 |
| Saito E et al. | 7-ketocholesterol, a major oxysterol, promotes pi-induced vascular calcification in cultured smooth muscle cells. | 2008 | J. Atheroscler. Thromb. | pmid:18603819 |
| Grigore L et al. | Combination therapy in cholesterol reduction: focus on ezetimibe and statins. | 2008 | Vasc Health Risk Manag | pmid:18561502 |
| Sharyo S et al. | Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway. | 2008 | Kidney Int. | pmid:18509318 |
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| Tekle M et al. | Investigation of coenzyme Q biosynthesis in human fibroblast and HepG2 cells. | 2008 | J. Biochem. Biophys. Methods | pmid:17916383 |
| Cornish J et al. | Modulation of osteoclastogenesis by fatty acids. | 2008 | Endocrinology | pmid:18617622 |
| Okada K et al. | Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. | 2008 | Plant Cell Physiol. | pmid:18303110 |
| Lüdke SM et al. | Stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 2008 | J. Lipid Res. | pmid:18669481 |
| Carrasco MP et al. | Hexadecylphosphocholine interferes with the intracellular transport of cholesterol in HepG2 cells. | 2008 | FEBS J. | pmid:18312412 |
| Winiarska M et al. | Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. | 2008 | PLoS Med. | pmid:18366248 |
| Oliveira KA et al. | Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction. | 2008 | J. Bioenerg. Biomembr. | pmid:18679777 |
| Chana RS et al. | Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis. | 2008 | Am. J. Nephrol. | pmid:18535368 |
| Sapir-Mir M et al. | Peroxisomal localization of Arabidopsis isopentenyl diphosphate isomerases suggests that part of the plant isoprenoid mevalonic acid pathway is compartmentalized to peroxisomes. | 2008 | Plant Physiol. | pmid:18988695 |
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| Acharjee S and Welty FK | Atorvastatin and cardiovascular risk in the elderly--patient considerations. | 2008 | Clin Interv Aging | pmid:18686752 |
| Journe F et al. | Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. | 2008 | Breast Cancer Res. Treat. | pmid:17333335 |
| Sando T et al. | Cloning and characterization of mevalonate pathway genes in a natural rubber producing plant, Hevea brasiliensis. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18685207 |
| Laezza C et al. | The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway. | 2008 | Endocr. Relat. Cancer | pmid:18676619 |
| Bate C et al. | Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells. | 2008 | BMC Biol. | pmid:18789130 |
| Kistowska M et al. | Dysregulation of the host mevalonate pathway during early bacterial infection activates human TCR gamma delta cells. | 2008 | Eur. J. Immunol. | pmid:18624305 |
| Matsuda T et al. | Simvastatin inhibits catecholamine secretion and synthesis induced by acetylcholine via blocking Na+ and Ca2+ influx in bovine adrenal medullary cells. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18593956 |
| Habara K et al. | Pitavastatin up-regulates the induction of iNOS through enhanced stabilization of its mRNA in pro-inflammatory cytokine-stimulated hepatocytes. | 2008 | Nitric Oxide | pmid:17936042 |
| Fried LF | Effects of HMG-CoA reductase inhibitors (statins) on progression of kidney disease. | 2008 | Kidney Int. | pmid:18528321 |
| Skorupinska-Tudek K et al. | Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. | 2008 | J. Biol. Chem. | pmid:18502754 |
| Zhang X et al. | Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. | 2008 | J. Immunol. | pmid:18453621 |
| Aprigliano I et al. | Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells. | 2008 | Liver Int. | pmid:18339080 |
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| Glynn SA et al. | The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. | 2008 | BMC Cancer | pmid:18199328 |
| Galichet A et al. | Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. | 2008 | Plant Physiol. | pmid:18184738 |
| Kodaman PH and Duleba AJ | Statins in the treatment of polycystic ovary syndrome. | 2008 | Semin. Reprod. Med. | pmid:18181091 |
| Wilson GJ et al. | Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review. | 2008 | Nutr Metab (Lond) | pmid:18173841 |
| Mathew B and Biju R | Neuroprotective effects of garlic a review. | 2008 | Libyan J Med | pmid:21499478 |
| Yoshida T et al. | Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. | 2008 | Anal Chem Insights | pmid:19609389 |
| Saito A et al. | Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells. | 2008 | Melanoma Res. | pmid:18337644 |
| Baba TT et al. | Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway. | 2008 | J. Muscle Res. Cell. Motil. | pmid:18792797 |
| Habeos IG et al. | Simvastatin activates Keap1/Nrf2 signaling in rat liver. | 2008 | J. Mol. Med. | pmid:18787804 |
| Osman L et al. | Atorvastatin accelerates extracellular nucleotide degradation in human endothelial cells. | 2008 | Mol. Cell. Biochem. | pmid:18158588 |
| Martin-Ventura JL et al. | LDL induces parathyroid hormone-related protein expression in vascular smooth muscle cells: Modulation by simvastatin. | 2008 | Atherosclerosis | pmid:18378243 |
| Baldi A and Dixit VK | Yield enhancement strategies for artemisinin production by suspension cultures of Artemisia annua. | 2008 | Bioresour. Technol. | pmid:17804216 |
| Park SY et al. | Inhibitory effect of simvastatin on the TNF-alpha- and angiotensin II-induced monocyte adhesion to endothelial cells is mediated through the suppression of geranylgeranyl isoprenoid-dependent ROS generation. | 2008 | Arch. Pharm. Res. | pmid:18365690 |
| Begley M et al. | Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection. | 2008 | Infect. Immun. | pmid:18765739 |
| Zhuge B et al. | Bioconversion of lovastatin to a novel statin by Amycolatopsis sp. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18368405 |
| Kaliszewski P et al. | Rsp5p ubiquitin ligase and the transcriptional activators Spt23p and Mga2p are involved in co-regulation of biosynthesis of end products of the mevalonate pathway and triacylglycerol in yeast Saccharomyces cerevisiae. | 2008 | Biochim. Biophys. Acta | pmid:18771750 |
| Voynova NE et al. | Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. | 2008 | Arch. Biochem. Biophys. | pmid:18823933 |
| Pscheidt B and Glieder A | Yeast cell factories for fine chemical and API production. | 2008 | Microb. Cell Fact. | pmid:18684335 |
| Schwartz YSh et al. | Cholesterol-induced stimulation of postinflammatory liver fibrosis. | 2008 | Bull. Exp. Biol. Med. | pmid:19110552 |
| Liang YJ et al. | Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products. | 2008 | Cardiology | pmid:18057884 |
| Yu F et al. | Isolation and functional characterization of a beta-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith. | 2008 | FEBS Lett. | pmid:18242187 |
| Lazzerini PE et al. | Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients. | 2007 Sep-Oct | Clin. Exp. Rheumatol. | pmid:18078616 |
| Yoon SH et al. | Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. | 2007 May-Jun | Biotechnol. Prog. | pmid:17500531 |
| Matsunaga S et al. | Incadronate induces cell detachment and apoptosis in prostatic PC-3 cells. | 2007 Mar-Apr | Anticancer Res. | pmid:17465222 |
| Bock O et al. | Common musculoskeletal adverse effects of oral treatment with once weekly alendronate and risedronate in patients with osteoporosis and ways for their prevention. | 2007 Apr-Jun | J Musculoskelet Neuronal Interact | pmid:17627083 |
| Kuroda M et al. | Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus. | 2007 | J. Antimicrob. Chemother. | pmid:17242033 |
| Yoon SH et al. | Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17115209 |
| Ye J | Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus. | 2007 | PLoS Pathog. | pmid:17784784 |
| Tanaka T et al. | Lipophilic statins suppress cytotoxicity by freshly isolated natural killer cells through modulation of granule exocytosis. | 2007 | Int. Immunol. | pmid:17182966 |
| Saijonmaa O et al. | Atorvastatin inhibits angiotensin-converting enzyme induction in differentiating human macrophages. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17158648 |
| Nishimoto T et al. | Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17599378 |
| Honda A et al. | Highly sensitive assay of HMG-CoA reductase activity by LC-ESI-MS/MS. | 2007 | J. Lipid Res. | pmid:17272831 |
| Sarrabayrouse G et al. | Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells. | 2007 | Neoplasia | pmid:18084615 |
| Bretón MartÃnez JR et al. | Mevalonic aciduria: report of two cases. | 2007 | J. Inherit. Metab. Dis. | pmid:17578678 |
| Ben-Tal Cohen E et al. | Statins decrease TNF-alpha-induced osteoprotegerin production by endothelial cells and smooth muscle cells in vitro. | 2007 | Biochem. Pharmacol. | pmid:17070781 |
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| Haas D and Hoffmann GF | Mevalonate kinase deficiency and autoinflammatory disorders. | 2007 | N. Engl. J. Med. | pmid:17596600 |
| Maurer-Stroh S et al. | Towards complete sets of farnesylated and geranylgeranylated proteins. | 2007 | PLoS Comput. Biol. | pmid:17411337 |
| Llorente A et al. | Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells. | 2007 | Eur. J. Cell Biol. | pmid:17601634 |
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| Jahangir T and Sultana S | Perillyl Alcohol Protects Against Fe-NTA-Induced Nephrotoxicity and Early Tumor Promotional Events in Rat Experimental Model. | 2007 | Evid Based Complement Alternat Med | pmid:18227911 |
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| Hamadmad SN and Hohl RJ | Lovastatin suppresses erythropoietin receptor surface expression through dual inhibition of glycosylation and geranylgeranylation. | 2007 | Biochem. Pharmacol. | pmid:17586475 |
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| Ali F et al. | Statin-mediated cytoprotection of human vascular endothelial cells: a role for Kruppel-like factor 2-dependent induction of heme oxygenase-1. | 2007 | J. Thromb. Haemost. | pmid:17927807 |
| Arkwright PD et al. | Mevalonic aciduria cured by bone marrow transplantation. | 2007 | N. Engl. J. Med. | pmid:17898110 |
| Merrell MA et al. | Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells. | 2007 | Eur. J. Pharmacol. | pmid:17640631 |
| Zeiser R et al. | Preemptive HMG-CoA reductase inhibition provides graft-versus-host disease protection by Th-2 polarization while sparing graft-versus-leukemia activity. | 2007 | Blood | pmid:17827390 |
| Wong J et al. | Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol. | 2007 | Lipids Health Dis | pmid:17408498 |
| Hunter WN | The non-mevalonate pathway of isoprenoid precursor biosynthesis. | 2007 | J. Biol. Chem. | pmid:17442674 |
| Lopes AA et al. | Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae). | 2007 | Phytochemistry | pmid:17574633 |
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| Towler MJ and Weathers PJ | Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways. | 2007 | Plant Cell Rep. | pmid:17710406 |
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| Byres E et al. | Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity. | 2007 | J. Mol. Biol. | pmid:17583736 |
| Lee MH et al. | Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation. | 2007 | Stem Cells | pmid:17464088 |
| Kinjoh T et al. | Control of juvenile hormone biosynthesis in Bombyx mori: cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata. | 2007 | Insect Biochem. Mol. Biol. | pmid:17628279 |
| Takahashi HK et al. | Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction. | 2007 | Clin. Immunol. | pmid:17482516 |