Mevalonic acid

Mevalonic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 10134 references associated with Mevalonic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Mevalonic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Mevalonic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Per page 10 20 50 | Total 25

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All references with Mevalonic acid

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Per page 10 20 50 100 | Total 2899
Authors Title Published Journal PubMed Link
Ahmad N and Siddiqi M Bacterial metabolism of 3-hydroxy-3-methylglutaric acid. 1973 J. Bacteriol. pmid:4717513
pmid:4713154
Bojesen E et al. Sterol biosynthesis in vitro of rat renal inner medulla. 1973 Biochim. Biophys. Acta pmid:4713153
Sodhi HS et al. Separate pools for endogenous and exogenous cholesterol in rat intestines. 1973 Mar-Apr Atherosclerosis pmid:4709120
Hellstrom KH et al. Studies of the in vivo metabolism of mevalonic acid in the normal rat. 1973 J. Clin. Invest. pmid:4703220
pmid:4700204
Edwards PA Effect of adrenalectomy and hypophysectomy on the circadian rhythm of -hydroxy- -methylglutaryl coenzyme A reductase activity in rat liver. 1973 J. Biol. Chem. pmid:4697401
Sodhi HS et al. Hypocholesterolemic agents and mobilization of tissue cholesterol in man. 1973 Jan-Feb Atherosclerosis pmid:4696743
Miettinen TA Mode of action of a new hypocholesteraemic drug (DH-581) in familial hypercholesteraemia. 1972 Mar-Apr Atherosclerosis pmid:4666121
pmid:4663657
Gregory KW et al. Diurnal variations in rat liver 3-hydroxy-3-methylglutaryl-Coenzyme A reductase activity in relation to feeding. 1972 Biochem. J. pmid:4656802
Atkin SD et al. The isolation of 2,3-oxidosqualene from the liver of rats treated with 1-dodecylimidazole, a novel hypocholesterolaemic agent. 1972 Biochem. J. pmid:4655417
Malhotra HC and Nes WR The conversion of mevalonate to 24-methylenecycloartanol by a cell-free enzyme preparation from nonphotosynthetic tissue. 1972 J. Biol. Chem. pmid:4651646
Ahmed AA et al. Effect of milk constituents on hepatic cholesterol-genesis. 1979 Atherosclerosis pmid:465119
Tabacik C et al. Cholesterogenesis induction in human lymphocytes by sterols efflux or phytohemagglutinin stimulation : cellular division as the requirement for efficient cholesterol biosynthesis in lymphocytes. 1979 Biochem. Biophys. Res. Commun. pmid:465064
Wiley MH et al. Conversion of mevalonolactone to its open-chain salt by a serum enzyme. 1979 Biochem. Biophys. Res. Commun. pmid:465057
Prottey C et al. Lipid synthesis in rat skin. 1972 Br. J. Dermatol. pmid:4648803
Richards JB and Hemming FW Dolichols, ubiquinones, geranylgeraniol and farnesol as the major metabolites of mevalonate in Phytophthora cactorum. 1972 Biochem. J. pmid:4643705
Milborrow BV Stereochemical aspects of the formation of double bonds in abscisic acid. 1972 Biochem. J. pmid:4643698
Mak KM and Trier JS Radioautographic and chemical evidence for (5- 3 H)mevalonate incorporation into cholesterol by rat villous absorptive cells. 1972 Biochim. Biophys. Acta pmid:4642214
Cuzzopoli M et al. Effect of nephrectomy and cholesterol feeding on the metabolism of intravenously administered DL-mevalonate in the rat. 1972 Metab. Clin. Exp. pmid:4641957
White LW Feedback regulation of cholesterol biosynthesis: studies with cholestyramine. 1972 Circ. Res. pmid:4641786
Goldfarb S and Pitot HC Stimulatory effect of dietary lipid and cholestyramine on hepatic HMG CoA reductase. 1972 J. Lipid Res. pmid:4641420
Edgren B and Hellström K Lipid biosynthesis from DL (2- 14 C) mevalonic acid in intact mice and rabbits. 1972 Acta Physiol. Scand. pmid:4640173
Jedlicki E et al. Stereospecificity of isopentenylpyrophosphate isomerase and prenyl transferase from pinus and citrus. 1972 Arch. Biochem. Biophys. pmid:4635785
Thorne KJ and Barker DC The occurrence of bactoprenol in the mesosome and plasma membranes of Lactobacillus casei and Lactobacillus plantarum. 1972 J. Gen. Microbiol. pmid:4625239
Lehner ND et al. Effects of insulin deficiency, hypothyroidism, and hypertension on cholesterol metabolism in the squirrel monkey. 1972 Exp. Mol. Pathol. pmid:4622478
Hatanaka H et al. Accumulation of a sterol intermediate during reaction in the presence of homocysteine with cell-free extract of yeast. 1974 Biochem. Biophys. Res. Commun. pmid:4608604
Kabara JJ A critical review of brain cholesterol metabolism. 1973 Prog. Brain Res. pmid:4608424
Madhosingh C et al. Inhibition of yeast hydroxymethylglutaryl-CoA reductase by a rat liver mitochondrial preparation. 1974 FEBS Lett. pmid:4607673
pmid:4598335
Cornforth JW et al. Substrate stereochemistry of 3-hydroxy-3-methylglutaryl-coenzyme A synthase. 1974 Eur. J. Biochem. pmid:4597848
Higgins MJ and Kekwick RG An investigation into the role of malonyl-coenzyme A in isoprenoid biosynthesis. 1973 Biochem. J. pmid:4579226
Shimizu I et al. Mevalonate synthesis in the mitochondria of yeast. 1973 Biochim. Biophys. Acta pmid:4569545
Nomura S et al. Inhibition of sterol and fatty acid biosyntheses by cerulenin in cell-free systems of yeast. 1972 J. Antibiot. pmid:4568013
pmid:4557431
Trumpower BL et al. Studies on ubiquinone. The isolation and identification of 5-demethoxyubiquinone-9 as an intermediate in biosynthesis of ubiquinone-9 in the rat. 1972 J. Biol. Chem. pmid:4553441
Salen G and Polito A Biosynthesis of 5 -cholestan-3 -ol in cerebrotendinous xanthomatosis. 1972 J. Clin. Invest. pmid:4550120
Ness GC et al. Stimulation of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity in hypophysectomized rats by L-triiodothyronine. 1973 Proc. Natl. Acad. Sci. U.S.A. pmid:4521209
Mitropoulos KA et al. Cholesterol precursor pools for the synthesis of cholic and chemodeoxycholic acids in rats. 1974 J. Biol. Chem. pmid:4472769
Overton KH and Roberts FM Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata. 1974 Biochem. J. pmid:4468823
Calandra S et al. Cholesterol synthesis in isolated rat hepatocytes. In vitro effect os sterols and bile acids. 1979 Exp. Mol. Pathol. pmid:446695
Beedle AS et al. Some properties and a suggested reclassification of mevaldate reductase. 1974 Biochem. J. pmid:4463942
Shapiro DJ et al. Micro assay for 3-hydroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts. 1974 Biochim. Biophys. Acta pmid:4441486
Ramsey RB et al. The effect of non-ionic detergents and phospholipase A on enzymes involved in adult rat brain sterol biosynthesis from (2-14C)-mevalonic acid in vitro. 1974 Biochem. Biophys. Res. Commun. pmid:4441393
Olson RJ et al. Alterations in cholesterol and fatty acid biosynthesis in rat liver homogenates by aryloxy acids. 1974 Biochem. J. pmid:4441387
Smith AG and Goad LJ Sterol biosynthesis by the sea urchin Echinus esculentus. 1974 Biochem. J. pmid:4441383
Brown MS and Goldstein JL Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol. 1974 J. Biol. Chem. pmid:4436312
Barr RM and De Luca LM The in vivo incorporation of mannose, retinol and mevalonic acid into phospholipids of hamster liver. 1974 Biochem. Biophys. Res. Commun. pmid:4421270
Cohen BI et al. Effects of clofibrate on sterol metabolism in the rat. 1974 Biochim. Biophys. Acta pmid:4418670
Hasan N and Durr IF Induction of beta-galactosidase in Lactobacillus plantarum. 1974 J. Bacteriol. pmid:4418576
Jakoi L and Quarfordt SH The induction of hepatic cholesterol synthesis in the rat by lecithin mesophase infusions. 1974 J. Biol. Chem. pmid:4416309
Dietschy JM and Brown MS Effect of alterations of the specific activity of the intracellular acetyl CoA pool on apparent rates of hepatic cholesterogenesis. 1974 J. Lipid Res. pmid:4413018
Mitlin N and Hedin PA Biosynthesis of grandlure, the pheromone of the boll weevil, Anthonomus grandis, from acetate, mevalonate, and glucose. 1974 J. Insect Physiol. pmid:4412207
Beedle AS et al. The stereochemistry of the reduction of mevaldic acid-coenzyme A hemithioacetal by rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1972 FEBS Lett. pmid:4405222
Madyastha KM et al. Carboxyl group methylation of loganic acid by a cell-free enzyme preparation from Vinca rosea. 1972 Biochem. J. pmid:4404427
Walton MJ and Pennock JF Some studies on the biosynthesis of ubiguinone, isoprenoid alcohols, squalene and sterols by marine invertebrates. 1972 Biochem. J. pmid:4403925
Beedle AS et al. The stereochemistry of hydrogen transfer from NADPH catalysed by 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver. 1972 Eur. J. Biochem. pmid:4403574
Gaskin F and Clayton RB An interstrain difference in cholesterol synthesis in vitro in mice, dependent upon a difference in endogenous NADPH-generating capacity. 1972 J. Lipid Res. pmid:4400581
Gaskin F and Clayton RB Decreased availability of hepatic NADPH in stressed mice. 1972 Biochem. Biophys. Res. Commun. pmid:4400445
Dugan RE and Porter JW Stereospecificity of the transfer of hydrogen from reduced nicotinamide adenine dinucleotide phosphate in each of the two reductive steps catalyzed by beta-hydroxy-beta-methylglutaryl coenzyme A reductase. 1971 J. Biol. Chem. pmid:4398469
Moir NJ et al. Effect of cholestyramine on the terminal reactions of sterol biosynthesis. 1970 Arch. Biochem. Biophys. pmid:4395692
Hamprecht B and Lynen F [Procedure to determine 3-hydroxy-3-methylglutaryl coenzyme A reductase in rat liver]. 1970 Eur. J. Biochem. pmid:4394155
Durr IF and Habbal MZ Mevalonate metabolism in supernatant fractions of lysates of Lactobacillus plantarum. 1970 J. Bacteriol. pmid:4392896
Hepper CM and Audley BG Th biosynthesis of rubber from beta-hydroxy-beta-methylgluarylcoenzyme A in Hevea brasiliensis latex. 1969 Biochem. J. pmid:4390212
Kandutsch AA and Saucier SE Prevention of cyclic and triton-induced increases in hydroxymethylglutaryl coenzyme A reductase and sterol synthesis by puromycin. 1969 J. Biol. Chem. pmid:4389023
Cayen MN and Dvornik D Effect of diosgenin on lipid metabolism in rats. 1979 J. Lipid Res. pmid:438658
pmid:4385596
Dempsey ME Inhibition of lipid biosynthesis. 1968 Ann. N. Y. Acad. Sci. pmid:4385358
Charlton JM et al. Incorporation of 2-[14C]mevalonic acid into phytoene by isolated chloroplasts. 1967 Biochem. J. pmid:4383323
Dennis DT and West CA Biosynthesis of gibberellins. 3. The conversion of (-)-kaurene to (-)-kauren-19-oic acid in endosperm of Echinocystis macrocarpa Greene. 1967 J. Biol. Chem. pmid:4382094
Graebe JE Isoprenoid biosynthesis in a cell-free system from pea shoots. 1967 Science pmid:4381746
Linn TC The demonstration and solubilization of beta-hydroxy-beta-methylglutaryl coenzyme A reductase from rat liver microsomes. 1967 J. Biol. Chem. pmid:4381458
Caravaca J and May MD The isolation and properties of an active peroxidase from hepatocatalase. 1964 Biochem. Biophys. Res. Commun. pmid:4380864
Hsu RY et al. The purification and properties of the fatty acid synthetase of pigeon liver. 1965 J. Biol. Chem. pmid:4378857
Klauda HC and Zilversmit DB Influx of cholesterol into plasma in rabbits with fasting hyperbetalipoproteinemia. 1974 J. Lipid Res. pmid:4372287
Kirsten ES and Watson JA Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins. 1974 J. Biol. Chem. pmid:4371188
Brown MS et al. Properties of 3-hydroxy-3-methylglutaryl coenzyme A reductase solubilized from rat liver and hepatoma. 1974 J. Biol. Chem. pmid:4370978
Luskey KL et al. Stimulation of the synthesis of very low density lipoproteins in rooster liver by estradiol. 1974 J. Biol. Chem. pmid:4370392
Dempsey ME Regulation of steroid biosynthesis. 1974 Annu. Rev. Biochem. pmid:4369131
Goldstein JL and Brown MS Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia. 1974 J. Biol. Chem. pmid:4368448
pmid:4364768
Nepokroeff CM et al. Regulation of the diurnal rhythm of rat liver beta-hydroxy-beta-methylglutaryl coenzmye A reductase activity by insulin, glucagon, cyclic AMP and hydrocortisone. 1974 Arch. Biochem. Biophys. pmid:4364764
Imblum RL and Rodwell VW 3-Hydroxy-3-methylglutaryl CoA reductase and mevalonate kinase of Neurospora crassa. 1974 J. Lipid Res. pmid:4363966
Brown MS and Goldstein JL Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. 1974 Proc. Natl. Acad. Sci. U.S.A. pmid:4362634
Cayen MN Effect of dietary tomatine on cholesterol metabolism in the rat. 1971 J. Lipid Res. pmid:4362143
pmid:4361551
Bricker LA et al. Effects of dietary cholesterol on bile acid synthesis in liver and hepatomas. 1974 Cancer Res. pmid:4359874
Brown MS et al. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia. 1974 J. Biol. Chem. pmid:4359767
Barter PJ Origin of esterified cholesterol transported in the very low density lipoproteins of human plasma. 1974 J. Lipid Res. pmid:4359537
Hochberg RB et al. Cholesterol sulfate: some aspects of its biosynthesis and uptake by tissues from blood. 1974 Endocrinology pmid:4358029
pmid:4356818
Myant NB et al. Turnover of cholesteryl esters in plasma low-density and high-density lipoproteins in familial hyperbetalipoproteinaemia. 1973 Clin Sci Mol Med pmid:4356485
Derksen A and Cohen P Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro. 1973 J. Biol. Chem. pmid:4355579
Goldstein JL and Brown MS Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol. 1973 Proc. Natl. Acad. Sci. U.S.A. pmid:4355366
Grigor MR et al. Cholesterol metabolism in rats bearing Morris hepatoma 7777. 1973 Cancer Res. pmid:4352741
Slakey LL et al. Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. 1973 J. Lipid Res. pmid:4351784
Sodhi HS and Kudchodkar BJ Synthesis of cholesterol in hypercholesterolemia and its relationship to plasma trigylcerides. 1973 Metab. Clin. Exp. pmid:4351067
McIntyre N and Isselbacher KJ Role of the small intestine in cholesterol metabolism. 1973 Am. J. Clin. Nutr. pmid:4350610
Green TR and Baisted DJ Development of the activities of enzymes of the isoprenoid pathway during early stages of pea-seed germination. 1972 Biochem. J. pmid:4348263