| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
Total
3
1-Palmitoyl-sn-glycero-3-phosphocholine
1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.
Cross Reference
Introduction
To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine
PubChem Associated disorders and diseases
What pathways are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 1-Palmitoyl-sn-glycero-3-phosphocholine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Vesterqvist O et al. | Quantitation of lysophosphatidylcholine molecular species in rat cardiac tissue. | 1992 | Anal. Biochem. | pmid:1514697 |
| Wykle RL et al. | Biosynthesis of pulmonary surfactant: comparison of 1-palmitoyl-sn-glycero-3-phosphocholine and palmitate as precursors of dipalmitoyl-sn-glycero-3-phosphocholine in adenoma alveolar type II cells. | 1980 | Arch. Biochem. Biophys. | pmid:6892673 |
| Weiher B and Komnick H | Digestion of phosphatidylcholines, absorption, and esterification of lipolytic products by Aeshna cyanea larvae as studied in vivo and in vitro. | 1997 | Arch. Insect Biochem. Physiol. | pmid:9366012 |
| Iwase M et al. | Lysophosphatidylcholine contents in plasma LDL in patients with type 2 diabetes mellitus: relation with lipoprotein-associated phospholipase A2 and effects of simvastatin treatment. | 2008 | Atherosclerosis | pmid:17350631 |
| Sun GY et al. | Inhibition of acyl-CoA hydrolase activity in liver microsomes by lyso-phospholipids. | 1980 | Biochem. Biophys. Res. Commun. | pmid:6104963 |
| Metz SA | Metabolism of lysophospholipids in intact rat islets. The insulin secretagogue p-hydroxymercuribenzoic acid impairs lysophosphatidylcholine catabolism and permits its accumulation. | 1987 | Biochem. J. | pmid:3297039 |
| Okajima F et al. | Stimulatory and inhibitory actions of lysophosphatidylcholine, depending on its fatty acid residue, on the phospholipase C/Ca2+ system in HL-60 leukaemia cells. | 1998 | Biochem. J. | pmid:9820828 |
| Rüstow B et al. | Studies on the formation of dipalmitoyl species of phosphatidylcholine and phosphatidylethanolamine in pulmonary type II cells. | 1992 | Biochem. J. | pmid:1546960 |
| Catania VA et al. | Gender-related differences in the amount and functional state of rat liver UDP-glucuronosyltransferase. | 1995 | Biochem. Pharmacol. | pmid:7646557 |
| Wu H et al. | A slight asymmetry in the transbilayer distribution of lysophosphatidylcholine alters the surface properties and poly(ethylene glycol)-mediated fusion of dipalmitoylphosphatidylcholine large unilamellar vesicles. | 1996 | Biochemistry | pmid:8823198 |
| Alonso A et al. | Lipids favoring inverted phase enhance the ability of aerolysin to permeabilize liposome bilayers. | 2000 | Biochemistry | pmid:11087349 |
| Henshaw JB et al. | Definition of the specific roles of lysolecithin and palmitic acid in altering the susceptibility of dipalmitoylphosphatidylcholine bilayers to phospholipase A2. | 1998 | Biochemistry | pmid:9692961 |
| Haque ME and Lentz BR | Roles of curvature and hydrophobic interstice energy in fusion: studies of lipid perturbant effects. | 2004 | Biochemistry | pmid:15035621 |
| Ninio E et al. | Biosynthesis of platelet-activating factor (PAF-acether). V. Enhancement of acetyltransferase activity in murine peritoneal cells by calcium ionophore A23187. | 1983 | Biochim. Biophys. Acta | pmid:6405792 |
| Davidsen J et al. | Synergistic permeability enhancing effect of lysophospholipids and fatty acids on lipid membranes. | 2002 | Biochim. Biophys. Acta | pmid:12101020 |
| Wong PT et al. | Hydrogen bonding between anhydrous cholesterol and phosphatidylcholines: an infrared spectroscopic study. | 1989 | Biochim. Biophys. Acta | pmid:2923897 |
| Palmgren MG et al. | Effect of detergents on the H(+)-ATPase activity of inside-out and right-side-out plant plasma membrane vesicles. | 1990 | Biochim. Biophys. Acta | pmid:2154256 |
| Brentel I et al. | Phase equilibria of the ternary system 1-palmitoyl-sn-glycero-3-phosphocholine/oleic acid/water studied by NMR. | 1987 | Biochim. Biophys. Acta | pmid:3663679 |
| Killian JA et al. | Mixtures of gramicidin and lysophosphatidylcholine form lamellar structures. | 1983 | Biochim. Biophys. Acta | pmid:6187360 |
| Funkhouser JD et al. | Acylation of 1-palmitoyl-lysophosphatidylglycerol in a alveolar type II cells from rat lung. | 1981 | Biochim. Biophys. Acta | pmid:6895328 |
| Bador H et al. | Effects of 1-palmitoyl-sn-glycero-3-phosphorylcholine on the properties of a solubilized sialyltransferase activity from mouse liver. | 1982 | Biochim. Biophys. Acta | pmid:7126592 |
| van Heusden GP et al. | Selective utilization of palmitoyl lysophosphatidylcholine in this synthesis of disaturated phosphatidylcholine in rat lung: a combined in vitro and in vivo approach. | 1981 | Biochim. Biophys. Acta | pmid:7236698 |
| Baker RR and Chang HY | Phosphatidylcholine as a source of diacylglycerols in neuronal nuclei incubated in the presence of EGTA and CMP. | 1984 | Biochim. Biophys. Acta | pmid:6435679 |
| Wenk MR and Seelig J | Proton induced vesicle fusion and the isothermal lalpha-->HII phase transition of lipid bilayers: a 31P-NMR and titration calorimetry study. | 1998 | Biochim. Biophys. Acta | pmid:9675291 |
| Aranda FJ et al. | Capsaicin affects the structure and phase organization of phospholipid membranes. | 1995 | Biochim. Biophys. Acta | pmid:7696298 |
| Min J et al. | Lysophosphatidylcholine derived from deer antler extract suppresses hyphal transition in Candida albicans through MAP kinase pathway. | 2001 | Biochim. Biophys. Acta | pmid:11278174 |
| Husebye ES and Flatmark T | Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. | 1987 | Biochim. Biophys. Acta | pmid:3607074 |
| Lee YP et al. | Analysis of human lecithin-cholesterol acyltransferase activity by carboxyl-terminal truncation. | 1997 | Biochim. Biophys. Acta | pmid:9059515 |
| Siminovitch DJ et al. | High pressure infrared spectroscopy of lipid bilayers: new tests for interdigitation. | 1987 | Biochim. Biophys. Acta | pmid:3593709 |
| Mitchell NJ et al. | Branched phospholipids render lipid vesicles more susceptible to membrane-active peptides. | 2016 | Biochim. Biophys. Acta | pmid:26514602 |
| Naderi S et al. | Modulation of red blood cell sugar transport by lyso-lipid. | 1989 | Biochim. Biophys. Acta | pmid:2804103 |
| Therrien A et al. | Chemical and physical requirements for lipid extraction by bovine binder of sperm BSP1. | 2013 | Biochim. Biophys. Acta | pmid:22960042 |
| Bador H et al. | Temperature dependence of membranous and solubilized sialyltransferase activities in the presence of 1-palmitoyl-sn-glycero-3-phosphorylcholine and fatty acids. | 1984 | Biochimie | pmid:6743698 |
| Khodadad JK et al. | Remodeling the shape of the skeleton in the intact red cell. | 1996 | Biophys. J. | pmid:8789122 |
| Cherezov V et al. | Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase. | 2002 | Biophys. J. | pmid:12496106 |
| Hamed MM et al. | Behavior of amphipathic helices on analysis via matrix methods, with application to glucagon, secretin, and vasoactive intestinal peptide. | 1983 | Biopolymers | pmid:6850049 |
| Kühn T et al. | Higher plasma levels of lysophosphatidylcholine 18:0 are related to a lower risk of common cancers in a prospective metabolomics study. | 2016 | BMC Med | pmid:26817443 |
| Plane F et al. | Oxidative modification of low-density lipoproteins and the inhibition of relaxations mediated by endothelium-derived nitric oxide in rabbit aorta. | 1992 | Br. J. Pharmacol. | pmid:1596684 |
| Wang J et al. | Potential mechanisms for the enhancement of HERG K+ channel function by phospholipid metabolites. | 2004 | Br. J. Pharmacol. | pmid:14744814 |
| Yamamoto N and Naraparaju VR | Vitamin D3-binding protein as a precursor for macrophage activating factor in the inflammation-primed macrophage activation cascade in rats. | 1996 | Cell. Immunol. | pmid:8660814 |
| Sato A et al. | Synthetic biotinylated peptide compound, BP21, specifically recognizes lysophosphatidylcholine micelles. | 2012 | Chem Biol Drug Des | pmid:22591064 |
| Traïkia M et al. | Impact of exogenous lysolipids on sensitive and multidrug resistant K562 cells: 1H NMR studies. | 2005 | Chem. Biol. Interact. | pmid:15698580 |
| Jansson M et al. | Magnetic alignment and orientational order of dipalmitoylphosphatidylcholine bilayers containing palmitoyllysophosphatidylcholine. | 1990 | Chem. Phys. Lipids | pmid:2225236 |
| Teruel JA et al. | On the effect of lysophosphatidylcholine, platelet activating factor and other surfactants on calcium permeability in sarcoplasmic reticulum vesicles. | 1991 | Chem. Phys. Lipids | pmid:1790577 |
| Maloney KM and Grainger DW | Phase separated anionic domains in ternary mixed lipid monolayers at the air-water interface. | 1993 | Chem. Phys. Lipids | pmid:8348675 |
| Bartucci R et al. | Spin-label electron spin resonance studies of micellar dispersions of PEGs-PEs polymer-lipids. | 2003 | Chem. Phys. Lipids | pmid:12818737 |
| Heffern CT et al. | Thermodynamic and kinetic investigations of the release of oxidized phospholipids from lipid membranes and its effect on vascular integrity. | 2013 Oct-Nov | Chem. Phys. Lipids | pmid:23911706 |
| Fink KL and Gross RW | Modulation of canine myocardial sarcolemmal membrane fluidity by amphiphilic compounds. | 1984 | Circ. Res. | pmid:6091941 |
| Wang J et al. | Phospholipid metabolite 1-palmitoyl-lysophosphatidylcholine enhances human ether-a-go-go-related gene (HERG) K(+) channel function. | 2001 | Circulation | pmid:11723012 |