| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
Total
3
1-Palmitoyl-sn-glycero-3-phosphocholine
1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.
Cross Reference
Introduction
To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine
PubChem Associated disorders and diseases
What pathways are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 1-Palmitoyl-sn-glycero-3-phosphocholine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Günther-Ausborn S and Stegmann T | How lysophosphatidylcholine inhibits cell-cell fusion mediated by the envelope glycoprotein of human immunodeficiency virus. | 1997 | Virology | pmid:9281499 |
| Morito T et al. | Biphasic regulation of Fc-receptor mediated phagocytosis of rabbit alveolar macrophages by surfactant phospholipids. | 2000 | Tohoku J. Exp. Med. | pmid:10750736 |
| Long NP et al. | Development and assessment of a lysophospholipid-based deep learning model to discriminate geographical origins of white rice. | 2017 | Sci Rep | pmid:28819110 |
| Nagy-Szakal D et al. | Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. | 2018 | Sci Rep | pmid:29968805 |
| Mishig-Ochir T et al. | Cellular Membrane Composition Requirement by Antimicrobial and Anticancer Peptide GA-K4. | 2017 | Protein Pept. Lett. | pmid:27993125 |
| Sugasini D and Subbaiah PV | Rate of acyl migration in lysophosphatidylcholine (LPC) is dependent upon the nature of the acyl group. Greater stability of sn-2 docosahexaenoyl LPC compared to the more saturated LPC species. | 2017 | PLoS ONE | pmid:29117232 |
| Rich GT et al. | Towards an Understanding of the Low Bioavailability of Quercetin: A Study of Its Interaction with Intestinal Lipids. | 2017 | Nutrients | pmid:28165426 |
| Woo HK et al. | Nanostructure-initiator mass spectrometry: a protocol for preparing and applying NIMS surfaces for high-sensitivity mass analysis. | 2008 | Nat Protoc | pmid:18714302 |
| Chen WL et al. | Alterations in rat pulmonary phosphatidylcholines after chronic exposure to ambient fine particulate matter. | 2014 | Mol Biosyst | pmid:25236678 |
| Sonoki K et al. | Atherogenic role of lysophosphatidylcholine in low-density lipoprotein modified by phospholipase A2 and in diabetic patients: protection by nitric oxide donor. | 2003 | Metab. Clin. Exp. | pmid:12647268 |
| Sellner PA and Phillips AR | Phospholipid synthesis by chick retinal microsomes: fatty acid preference and effect of fatty acid binding protein. | 1991 | Lipids | pmid:2051885 |
| Nakagawa Y and Waku K | Synthesis of the dipalmitoyl species of diacyl glycerophosphocholine by rabbit alveolar macrophages. | 1986 | Lipids | pmid:3515098 |
| Neumüller W et al. | Enzymatic acylation of ether and ester lysophospholipids in rat liver microsomes. | 1987 | Lipids | pmid:3444370 |
| Yang Y et al. | Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. | 2014 | Lipids | pmid:24777581 |
| Cao LC et al. | Mitochondrial dysfunction is a primary event in renal cell oxalate toxicity. | 2004 | Kidney Int. | pmid:15496160 |
| Hara A et al. | Protective effects of dilazep and its derivative K-7259 on the haemolysis induced by amphiphiles in rat erythrocytes. | 1997 | J. Pharm. Pharmacol. | pmid:9379361 |
| Dannenberg AJ and Zakim D | Dietary lipid regulates the amount and functional state of UDP-glucuronosyltransferase in rat liver. | 1992 | J. Nutr. | pmid:1640253 |
| Sargent CA et al. | Effects of endogenous and exogenous lysophosphatidylcholine in isolated perfused rat hearts. | 1993 | J. Mol. Cell. Cardiol. | pmid:8263961 |
| Pulinilkunnil T et al. | Palmitoyl lysophosphatidylcholine mediated mobilization of LPL to the coronary luminal surface requires PKC activation. | 2004 | J. Mol. Cell. Cardiol. | pmid:15522270 |
| Delacroix H et al. | Freeze-fracture electron microscope study of lipid systems. The cubic phase of space group Pm3n. | 1993 | J. Mol. Biol. | pmid:8429561 |
| Chen Q and Nilsson A | Interconversion of alpha-linolenic acid in rat intestinal mucosa: studies in vivo and in isolated villus and crypt cells. | 1994 | J. Lipid Res. | pmid:7911819 |
| Wilson HM et al. | Structural basis of the phospholipid acyltransferase enzyme substrate specificity: a computer modeling study of the phospholipid acceptor molecule. | 1995 | J. Lipid Res. | pmid:7775855 |
| Matsubara T et al. | TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. | 2012 | J. Lipid Res. | pmid:23034213 |
| Takahashi H et al. | Metabolomics reveal 1-palmitoyl lysophosphatidylcholine production by peroxisome proliferator-activated receptor α. | 2015 | J. Lipid Res. | pmid:25510248 |
| Januszewski AS et al. | Chemical modification of proteins during peroxidation of phospholipids. | 2005 | J. Lipid Res. | pmid:15805546 |
| Silliman CC et al. | Partial characterization of lipids that develop during the routine storage of blood and prime the neutrophil NADPH oxidase. | 1994 | J. Lab. Clin. Med. | pmid:7964126 |
| Muñoz NM et al. | Transcellular secretion of group V phospholipase A2 from epithelium induces beta 2-integrin-mediated adhesion and synthesis of leukotriene C4 in eosinophils. | 2006 | J. Immunol. | pmid:16785555 |
| Silverman BA et al. | Effect of erythrocyte membrane modulation by lysolecithin on complement-mediated lysis. | 1984 | J. Immunol. | pmid:6690605 |
| Arbibe L et al. | Generation of lyso-phospholipids from surfactant in acute lung injury is mediated by type-II phospholipase A2 and inhibited by a direct surfactant protein A-phospholipase A2 protein interaction. | 1998 | J. Clin. Invest. | pmid:9739049 |
| Adachi J et al. | Detection of phosphatidylcholine oxidation products in rat heart using quadrupole time-of-flight mass spectrometry. | 2005 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:16055051 |
| Blondeau N et al. | A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures. | 2002 | J. Cereb. Blood Flow Metab. | pmid:12142567 |
| Zakim D et al. | Phospholipids and UDP-glucuronosyltransferase. Structure/function relationships. | 1988 | J. Biol. Chem. | pmid:3128536 |
| Chai YC et al. | Oxidized low density lipoprotein and lysophosphatidylcholine stimulate cell cycle entry in vascular smooth muscle cells. Evidence for release of fibroblast growth factor-2. | 1996 | J. Biol. Chem. | pmid:8663300 |
| Six DA and Dennis EA | Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity. | 2003 | J. Biol. Chem. | pmid:12672805 |
| Tamura A et al. | Quantitative studies on translocation and metabolic conversion of lysophosphatidylcholine incorporated into the membrane of intact human erythrocytes from the medium. | 1985 | J. Biochem. | pmid:3997795 |
| Grossmann G et al. | Experimental neonatal respiratory failure induced by lysophosphatidylcholine: effect of surfactant treatment. | 1999 | J. Appl. Physiol. | pmid:9931201 |
| Broniatowski M et al. | Grazing incidence diffraction and X-ray reflectivity studies of the interactions of inorganic mercury salts with membrane lipids in Langmuir monolayers at the air/water interface. | 2010 | J Phys Chem B | pmid:20604557 |
| Zhang H et al. | Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. | 2014 | J Ethnopharmacol | pmid:24709313 |
| Sánchez M et al. | Permeabilization of biological and artificial membranes by a bacterial dirhamnolipid produced by Pseudomonas aeruginosa. | 2010 | J Colloid Interface Sci | pmid:19837413 |
| Minami T et al. | Phospholipase A2 stimulates rat gastric epithelial cell line (RGM-1) migration. | 1997 | Inflamm. Res. | pmid:9098723 |
| Hung ND et al. | Prevention of 1-palmitoyl lysophosphatidylcholine-induced inflammation by polyunsaturated acyl lysophosphatidylcholine. | 2012 | Inflamm. Res. | pmid:22252240 |
| Angelico M et al. | Impaired hepatic handling and processing of lysophosphatidylcholine in rats with liver cirrhosis. | 1991 | Gastroenterology | pmid:2044911 |
| Alberghina M et al. | 1-Acyl-2-lysophosphatidylcholine transport across the blood-retina and blood-brain barrier. | 1994 | FEBS Lett. | pmid:8082761 |
| Nakai K et al. | Lipid peroxidation-induced VEGF expression in the skin of KKAy obese mice. | 2011 | Exp. Dermatol. | pmid:21355888 |
| Shi A et al. | Lysophosphatidylcholine molecular species in low density lipoprotein and high density lipoprotein in alloxan-induced diabetic rats: effect of probucol. | 1999 | Exp. Clin. Endocrinol. Diabetes | pmid:10543409 |
| Arvidson G et al. | Phase equilibria in four lysophosphatidylcholine/water systems. Exceptional behaviour of 1-palmitoyl-glycerophosphocholine. | 1985 | Eur. J. Biochem. | pmid:4054132 |
| Lux G et al. | Phospholipase A(2)-catalyzed acylation of lysophospholipids analyzed by experimental design. | 2014 | Enzyme Microb. Technol. | pmid:25152418 |
| Killian JA et al. | Induction of non-bilayer lipid structures by functional signal peptides. | 1990 | EMBO J. | pmid:2178926 |
| O'Hare MM et al. | Lyso-phosphatidylcholine and outcome of preterm babies with respiratory distress syndrome treated with surfactant. | 1997 | Early Hum. Dev. | pmid:9226120 |
| Ohkawa R et al. | Development of an enzymatic assay for sphingomyelin with rapid and automatable performances: Analysis in healthy subjects and coronary heart disease patients. | 2012 | Clin. Biochem. | pmid:22820437 |