1-Palmitoyl-sn-glycero-3-phosphocholine

1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.

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Introduction

To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine

MeSH term MeSH ID Detail
Arrhythmias, Cardiac D001145 42 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Hemolysis D006461 131 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

Related references are published most in these journals:

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What functions are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 1-Palmitoyl-sn-glycero-3-phosphocholine

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Authors Title Published Journal PubMed Link
Blondeau N et al. A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures. 2002 J. Cereb. Blood Flow Metab. pmid:12142567
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Chai YC et al. Oxidized low density lipoprotein and lysophosphatidylcholine stimulate cell cycle entry in vascular smooth muscle cells. Evidence for release of fibroblast growth factor-2. 1996 J. Biol. Chem. pmid:8663300
Six DA and Dennis EA Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity. 2003 J. Biol. Chem. pmid:12672805
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Broniatowski M et al. Grazing incidence diffraction and X-ray reflectivity studies of the interactions of inorganic mercury salts with membrane lipids in Langmuir monolayers at the air/water interface. 2010 J Phys Chem B pmid:20604557
Zhang H et al. Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. 2014 J Ethnopharmacol pmid:24709313
Sánchez M et al. Permeabilization of biological and artificial membranes by a bacterial dirhamnolipid produced by Pseudomonas aeruginosa. 2010 J Colloid Interface Sci pmid:19837413
Hung ND et al. Prevention of 1-palmitoyl lysophosphatidylcholine-induced inflammation by polyunsaturated acyl lysophosphatidylcholine. 2012 Inflamm. Res. pmid:22252240