MeSH term | MeSH ID | Detail |
---|---|---|
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.
To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine
MeSH term | MeSH ID | Detail |
---|---|---|
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Blondeau N et al. | A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures. | 2002 | J. Cereb. Blood Flow Metab. | pmid:12142567 |
Zakim D et al. | Phospholipids and UDP-glucuronosyltransferase. Structure/function relationships. | 1988 | J. Biol. Chem. | pmid:3128536 |
Chai YC et al. | Oxidized low density lipoprotein and lysophosphatidylcholine stimulate cell cycle entry in vascular smooth muscle cells. Evidence for release of fibroblast growth factor-2. | 1996 | J. Biol. Chem. | pmid:8663300 |
Six DA and Dennis EA | Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity. | 2003 | J. Biol. Chem. | pmid:12672805 |
Tamura A et al. | Quantitative studies on translocation and metabolic conversion of lysophosphatidylcholine incorporated into the membrane of intact human erythrocytes from the medium. | 1985 | J. Biochem. | pmid:3997795 |
Grossmann G et al. | Experimental neonatal respiratory failure induced by lysophosphatidylcholine: effect of surfactant treatment. | 1999 | J. Appl. Physiol. | pmid:9931201 |
Broniatowski M et al. | Grazing incidence diffraction and X-ray reflectivity studies of the interactions of inorganic mercury salts with membrane lipids in Langmuir monolayers at the air/water interface. | 2010 | J Phys Chem B | pmid:20604557 |
Zhang H et al. | Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. | 2014 | J Ethnopharmacol | pmid:24709313 |
Sánchez M et al. | Permeabilization of biological and artificial membranes by a bacterial dirhamnolipid produced by Pseudomonas aeruginosa. | 2010 | J Colloid Interface Sci | pmid:19837413 |
Hung ND et al. | Prevention of 1-palmitoyl lysophosphatidylcholine-induced inflammation by polyunsaturated acyl lysophosphatidylcholine. | 2012 | Inflamm. Res. | pmid:22252240 |