1-Palmitoyl-sn-glycero-3-phosphocholine

1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.

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Introduction

To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

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What functions are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1-Palmitoyl-sn-glycero-3-phosphocholine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 1-Palmitoyl-sn-glycero-3-phosphocholine

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Authors Title Published Journal PubMed Link
pmid:
Vesterqvist O et al. Quantitation of lysophosphatidylcholine molecular species in rat cardiac tissue. 1992 Anal. Biochem. pmid:1514697
Wykle RL et al. Biosynthesis of pulmonary surfactant: comparison of 1-palmitoyl-sn-glycero-3-phosphocholine and palmitate as precursors of dipalmitoyl-sn-glycero-3-phosphocholine in adenoma alveolar type II cells. 1980 Arch. Biochem. Biophys. pmid:6892673
Weiher B and Komnick H Digestion of phosphatidylcholines, absorption, and esterification of lipolytic products by Aeshna cyanea larvae as studied in vivo and in vitro. 1997 Arch. Insect Biochem. Physiol. pmid:9366012
Iwase M et al. Lysophosphatidylcholine contents in plasma LDL in patients with type 2 diabetes mellitus: relation with lipoprotein-associated phospholipase A2 and effects of simvastatin treatment. 2008 Atherosclerosis pmid:17350631
Sun GY et al. Inhibition of acyl-CoA hydrolase activity in liver microsomes by lyso-phospholipids. 1980 Biochem. Biophys. Res. Commun. pmid:6104963
Metz SA Metabolism of lysophospholipids in intact rat islets. The insulin secretagogue p-hydroxymercuribenzoic acid impairs lysophosphatidylcholine catabolism and permits its accumulation. 1987 Biochem. J. pmid:3297039
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Henshaw JB et al. Definition of the specific roles of lysolecithin and palmitic acid in altering the susceptibility of dipalmitoylphosphatidylcholine bilayers to phospholipase A2. 1998 Biochemistry pmid:9692961
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Palmgren MG et al. Effect of detergents on the H(+)-ATPase activity of inside-out and right-side-out plant plasma membrane vesicles. 1990 Biochim. Biophys. Acta pmid:2154256
Brentel I et al. Phase equilibria of the ternary system 1-palmitoyl-sn-glycero-3-phosphocholine/oleic acid/water studied by NMR. 1987 Biochim. Biophys. Acta pmid:3663679
Mitchell NJ et al. Branched phospholipids render lipid vesicles more susceptible to membrane-active peptides. 2016 Biochim. Biophys. Acta pmid:26514602
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Therrien A et al. Chemical and physical requirements for lipid extraction by bovine binder of sperm BSP1. 2013 Biochim. Biophys. Acta pmid:22960042