MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.
To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine
MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid: | ||||
Shi A et al. | Lysophosphatidylcholine molecular species in low density lipoprotein and high density lipoprotein in alloxan-induced diabetic rats: effect of probucol. | 1999 | Exp. Clin. Endocrinol. Diabetes | pmid:10543409 |
Morito T et al. | Biphasic regulation of Fc-receptor mediated phagocytosis of rabbit alveolar macrophages by surfactant phospholipids. | 2000 | Tohoku J. Exp. Med. | pmid:10750736 |
Alonso A et al. | Lipids favoring inverted phase enhance the ability of aerolysin to permeabilize liposome bilayers. | 2000 | Biochemistry | pmid:11087349 |
Min J et al. | Lysophosphatidylcholine derived from deer antler extract suppresses hyphal transition in Candida albicans through MAP kinase pathway. | 2001 | Biochim. Biophys. Acta | pmid:11278174 |
Wang J et al. | Phospholipid metabolite 1-palmitoyl-lysophosphatidylcholine enhances human ether-a-go-go-related gene (HERG) K(+) channel function. | 2001 | Circulation | pmid:11723012 |
Davidsen J et al. | Synergistic permeability enhancing effect of lysophospholipids and fatty acids on lipid membranes. | 2002 | Biochim. Biophys. Acta | pmid:12101020 |
Blondeau N et al. | A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures. | 2002 | J. Cereb. Blood Flow Metab. | pmid:12142567 |
Cherezov V et al. | Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase. | 2002 | Biophys. J. | pmid:12496106 |
Sonoki K et al. | Atherogenic role of lysophosphatidylcholine in low-density lipoprotein modified by phospholipase A2 and in diabetic patients: protection by nitric oxide donor. | 2003 | Metab. Clin. Exp. | pmid:12647268 |