MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.
To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine
MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Six DA and Dennis EA | Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity. | 2003 | J. Biol. Chem. | pmid:12672805 |
Bartucci R et al. | Spin-label electron spin resonance studies of micellar dispersions of PEGs-PEs polymer-lipids. | 2003 | Chem. Phys. Lipids | pmid:12818737 |
Wang J et al. | Potential mechanisms for the enhancement of HERG K+ channel function by phospholipid metabolites. | 2004 | Br. J. Pharmacol. | pmid:14744814 |
Haque ME and Lentz BR | Roles of curvature and hydrophobic interstice energy in fusion: studies of lipid perturbant effects. | 2004 | Biochemistry | pmid:15035621 |
Vesterqvist O et al. | Quantitation of lysophosphatidylcholine molecular species in rat cardiac tissue. | 1992 | Anal. Biochem. | pmid:1514697 |
Rüstow B et al. | Studies on the formation of dipalmitoyl species of phosphatidylcholine and phosphatidylethanolamine in pulmonary type II cells. | 1992 | Biochem. J. | pmid:1546960 |
Cao LC et al. | Mitochondrial dysfunction is a primary event in renal cell oxalate toxicity. | 2004 | Kidney Int. | pmid:15496160 |
Pulinilkunnil T et al. | Palmitoyl lysophosphatidylcholine mediated mobilization of LPL to the coronary luminal surface requires PKC activation. | 2004 | J. Mol. Cell. Cardiol. | pmid:15522270 |
Traïkia M et al. | Impact of exogenous lysolipids on sensitive and multidrug resistant K562 cells: 1H NMR studies. | 2005 | Chem. Biol. Interact. | pmid:15698580 |
Januszewski AS et al. | Chemical modification of proteins during peroxidation of phospholipids. | 2005 | J. Lipid Res. | pmid:15805546 |