MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
1-Palmitoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-palmitoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Intrahepatic Cholestasis and Dysentery, Shigella dysenteriae. The involved functions are known as Homeostasis, Signal Transduction, Saturated, mRNA Expression and Synthesis. 1-palmitoyl-sn-glycero-3-phosphocholine often locates in Hepatic. The associated genes with 1-Palmitoyl-sn-glycero-3-phosphocholine are PPARA gene, TGFBR2 gene, SMAD3 gene and PLA2G6 gene. The related lipids are Fatty Acids, palmitoyl lysophosphatidylcholine, LYSO-PC and 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine.
To understand associated biological information of 1-Palmitoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1-Palmitoyl-sn-glycero-3-phosphocholine is suspected in Intrahepatic Cholestasis, Dysentery, Shigella dysenteriae and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 1-Palmitoyl-sn-glycero-3-phosphocholine
MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Heffern CT et al. | Thermodynamic and kinetic investigations of the release of oxidized phospholipids from lipid membranes and its effect on vascular integrity. | 2013 Oct-Nov | Chem. Phys. Lipids | pmid:23911706 |
Zhang H et al. | Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. | 2014 | J Ethnopharmacol | pmid:24709313 |
Yang Y et al. | Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. | 2014 | Lipids | pmid:24777581 |
Lux G et al. | Phospholipase A(2)-catalyzed acylation of lysophospholipids analyzed by experimental design. | 2014 | Enzyme Microb. Technol. | pmid:25152418 |
Chen WL et al. | Alterations in rat pulmonary phosphatidylcholines after chronic exposure to ambient fine particulate matter. | 2014 | Mol Biosyst | pmid:25236678 |
Takahashi H et al. | Metabolomics reveal 1-palmitoyl lysophosphatidylcholine production by peroxisome proliferator-activated receptor α. | 2015 | J. Lipid Res. | pmid:25510248 |
Mitchell NJ et al. | Branched phospholipids render lipid vesicles more susceptible to membrane-active peptides. | 2016 | Biochim. Biophys. Acta | pmid:26514602 |
Kühn T et al. | Higher plasma levels of lysophosphatidylcholine 18:0 are related to a lower risk of common cancers in a prospective metabolomics study. | 2016 | BMC Med | pmid:26817443 |
Mishig-Ochir T et al. | Cellular Membrane Composition Requirement by Antimicrobial and Anticancer Peptide GA-K4. | 2017 | Protein Pept. Lett. | pmid:27993125 |
Naderi S et al. | Modulation of red blood cell sugar transport by lyso-lipid. | 1989 | Biochim. Biophys. Acta | pmid:2804103 |