MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
Arteriosclerosis | D001161 | 86 associated lipids |
Hyperlipidemias | D006949 | 73 associated lipids |
1-octadecanoyl-sn-glycero-3-phosphocholine is a lipid of Glycerophospholipids (GP) class. 1-octadecanoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Septicemia. The involved functions are known as Phosphorylation, MAP kinase activity, Phagocytosis, protein serine/threonine kinase activity and Uptake. The associated genes with 1-octadecanoyl-sn-glycero-3-phosphocholine are FPR1 gene and OLR1 gene. The related lipids are Lysophosphatidylcholines.
To understand associated biological information of 1-octadecanoyl-sn-glycero-3-phosphocholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
1-octadecanoyl-sn-glycero-3-phosphocholine is suspected in Septicemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 1-octadecanoyl-sn-glycero-3-phosphocholine
MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
Arteriosclerosis | D001161 | 86 associated lipids |
Hyperlipidemias | D006949 | 73 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Quan H et al. | Stearoyl lysophosphatidylcholine enhances the phagocytic ability of macrophages through the AMP-activated protein kinase/p38 mitogen activated protein kinase pathway. | 2016 | Int. Immunopharmacol. | pmid:27517519 |
Yang Y et al. | Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. | 2014 | Lipids | pmid:24777581 |
Zhang X et al. | Towards an understanding of the release behavior of temperature-sensitive liposomes: a possible explanation of the "pseudoequilibrium" release behavior at the phase transition temperature. | 2013 | J Liposome Res | pmid:23510297 |
Jung JH et al. | Inactivation of HDAC3 and STAT3 is critically involved in 1-stearoyl-sn-glycero-3-phosphocholine-induced apoptosis in chronic myelogenous leukemia K562 cells. | 2013 | Cell Biochem. Biophys. | pmid:23729004 |
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Tang D et al. | Quercetin prevents LPS-induced high-mobility group box 1 release and proinflammatory function. | 2009 | Am. J. Respir. Cell Mol. Biol. | pmid:19265175 |
Soga T et al. | Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15607732 |
Chen G et al. | Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis. | 2005 | J. Lipid Res. | pmid:15687351 |
Sonoki K et al. | Atherogenic role of lysophosphatidylcholine in low-density lipoprotein modified by phospholipase A2 and in diabetic patients: protection by nitric oxide donor. | 2003 | Metab. Clin. Exp. | pmid:12647268 |
Mansfield PJ et al. | Regulation of polymorphonuclear leukocyte degranulation and oxidant production by ceramide through inhibition of phospholipase D. | 2002 | Blood | pmid:11830497 |
Asai Y et al. | Characterization of the physicochemical properties of the micelles of platelet-activating factor (C18:0). | 2000 | Drug Dev Ind Pharm | pmid:10826115 |
Shi AH et al. | Lysophosphatidylcholine molecular species in low density lipoprotein of type 2 diabetes. | 1999 | Horm. Metab. Res. | pmid:10333086 |
Shi A et al. | Lysophosphatidylcholine molecular species in low density lipoprotein and high density lipoprotein in alloxan-induced diabetic rats: effect of probucol. | 1999 | Exp. Clin. Endocrinol. Diabetes | pmid:10543409 |
Günther-Ausborn S and Stegmann T | How lysophosphatidylcholine inhibits cell-cell fusion mediated by the envelope glycoprotein of human immunodeficiency virus. | 1997 | Virology | pmid:9281499 |
Vesterqvist O et al. | Quantitation of lysophosphatidylcholine molecular species in rat cardiac tissue. | 1992 | Anal. Biochem. | pmid:1514697 |
Zakim D et al. | Phospholipids and UDP-glucuronosyltransferase. Structure/function relationships. | 1988 | J. Biol. Chem. | pmid:3128536 |
Hui SW and Huang CH | X-ray diffraction evidence for fully interdigitated bilayers of 1-stearoyllysophosphatidylcholine. | 1986 | Biochemistry | pmid:3964679 |
Berdel WE et al. | Alkyl-lysophospholipids lack influence on the occurrence of radiation-induced lymphomas and AKR-leukemia. | 1983 | Cancer Lett. | pmid:6686802 |
Berdel WE et al. | Early tumor and leukemia response to alkyllysophospholipids in a phase I study. | 1982 | Cancer | pmid:7127246 |
Wu W et al. | Lamellar--micellar transition of 1-stearoyllysophosphatidylcholine assemblies in excess water. | 1982 | Biochemistry | pmid:7150539 |
King MT et al. | Failure to detect mutagenic effects of anti-tumor alkyl-lysophospholipids. | 1981 | Cancer Lett. | pmid:6790162 |
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