Lysophosphatidylcholine

Lysophosphatidylcholine is a lipid of Glycerophospholipids (GP) class. Lysophosphatidylcholine is associated with abnormalities such as Ischemia, Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver and Atherosclerosis. The involved functions are known as Inflammation, antagonists, Signal Transduction, Signal Pathways and Saturated. Lysophosphatidylcholine often locates in Body tissue, Head, integral to membrane, Membrane and Extracellular. The associated genes with Lysophosphatidylcholine are RHOA gene, Homologous Gene, GPR4 gene, GPR68 gene and TRPV2 gene. The related lipids are Nonesterified Fatty Acids, lysophosphatidylethanolamine, Lysophosphatidylcholines, Phosphatidylserines and 25-hydroxycholesterol. The related experimental models are Knock-out and Disease model.

Cross Reference

Introduction

To understand associated biological information of Lysophosphatidylcholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lysophosphatidylcholine?

Lysophosphatidylcholine is suspected in Atherosclerosis, Ischemia, Septicemia, Obesity, Exanthema, hypercholesterolemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lysophosphatidylcholine

MeSH term MeSH ID Detail
Arrhythmias, Cardiac D001145 42 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Insulinoma D007340 28 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Pulmonary Edema D011654 23 associated lipids
Peritonitis D010538 38 associated lipids
Proteinuria D011507 30 associated lipids
Arteriosclerosis D001161 86 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lysophosphatidylcholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lysophosphatidylcholine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lysophosphatidylcholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lysophosphatidylcholine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lysophosphatidylcholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lysophosphatidylcholine?

Knock-out

Knock-out are used in the study 'Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice.' (Parks BW et al., 2005) and Knock-out are used in the study 'Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A2.' (Fisher AB et al., 2005).

Disease model

Disease model are used in the study 'Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy.' (Thiele JR et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Lysophosphatidylcholine

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Per page 10 20 50 100 | Total 3448
Authors Title Published Journal PubMed Link
Wang J et al. Plasma lipidomic signatures of spontaneous obese rhesus monkeys. 2019 Lipids Health Dis pmid:30621707
Semba RD et al. Serum lipids in adults with late age-related macular degeneration: a case-control study. 2019 Lipids Health Dis pmid:30621701
Gayral M et al. The Spatiotemporal Deposition of Lysophosphatidylcholine Within Starch Granules of Maize Endosperm and its Relationships to the Expression of Genes Involved in Endoplasmic Reticulum-Amyloplast Lipid Trafficking and Galactolipid Synthesis. 2019 Plant Cell Physiol. pmid:30295886
Burton NO et al. Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response. 2018 Nat Commun pmid:30514845
Kuang A et al. Lipidomic Response to Coffee Consumption. 2018 Nutrients pmid:30513727
Fukushima K et al. Promotion of cell-invasive activity through the induction of LPA receptor-1 in pancreatic cancer cells. 2018 J. Recept. Signal Transduct. Res. pmid:30396320
Dorninger F et al. Alterations in the Plasma Levels of Specific Choline Phospholipids in Alzheimer's Disease Mimic Accelerated Aging. 2018 J. Alzheimers Dis. pmid:29480199
Habartová L et al. Chiroptical spectroscopy and metabolomics for blood-based sensing of pancreatic cancer. 2018 Chirality pmid:29473211
Matsuoka H et al. Neurotropin Accelerates the Differentiation of Schwann Cells and Remyelination in a Rat Lysophosphatidylcholine-Induced Demyelination Model. 2018 Int J Mol Sci pmid:29419802
Zhang M et al. UPLC/Q-TOF-MS-based metabolomics study of the anti-osteoporosis effects of Achyranthes bidentata polysaccharides in ovariectomized rats. 2018 Int. J. Biol. Macromol. pmid:29410058