| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperlipoproteinemia Type IV | D006953 | 6 associated lipids |
| Leukodystrophy, Globoid Cell | D007965 | 6 associated lipids |
| Plaque, Atherosclerotic | D058226 | 7 associated lipids |
| Abetalipoproteinemia | D000012 | 7 associated lipids |
| Cholecystitis | D002764 | 8 associated lipids |
| Sciatic Neuropathy | D020426 | 13 associated lipids |
| Carotid Stenosis | D016893 | 15 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Leukemia, Myeloid, Acute | D015470 | 19 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
Lysophosphatidylcholine
Lysophosphatidylcholine is a lipid of Glycerophospholipids (GP) class. Lysophosphatidylcholine is associated with abnormalities such as Ischemia, Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver and Atherosclerosis. The involved functions are known as Inflammation, antagonists, Signal Transduction, Signal Pathways and Saturated. Lysophosphatidylcholine often locates in Body tissue, Head, integral to membrane, Membrane and Extracellular. The associated genes with Lysophosphatidylcholine are RHOA gene, Homologous Gene, GPR4 gene, GPR68 gene and TRPV2 gene. The related lipids are Nonesterified Fatty Acids, lysophosphatidylethanolamine, Lysophosphatidylcholines, Phosphatidylserines and 25-hydroxycholesterol. The related experimental models are Knock-out and Disease model.
Cross Reference
Introduction
To understand associated biological information of Lysophosphatidylcholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lysophosphatidylcholine?
Lysophosphatidylcholine is suspected in Atherosclerosis, Ischemia, Septicemia, Obesity, Exanthema, hypercholesterolemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lysophosphatidylcholine
PubChem Associated disorders and diseases
What pathways are associated with Lysophosphatidylcholine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lysophosphatidylcholine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Lysophosphatidylcholine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Lysophosphatidylcholine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Lysophosphatidylcholine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Lysophosphatidylcholine?
Knock-out
Knock-out are used in the study 'Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice.' (Parks BW et al., 2005) and Knock-out are used in the study 'Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A2.' (Fisher AB et al., 2005).
Disease model
Disease model are used in the study 'Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy.' (Thiele JR et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Lysophosphatidylcholine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang J et al. | Plasma lipidomic signatures of spontaneous obese rhesus monkeys. | 2019 | Lipids Health Dis | pmid:30621707 |
| Semba RD et al. | Serum lipids in adults with late age-related macular degeneration: a case-control study. | 2019 | Lipids Health Dis | pmid:30621701 |
| Gayral M et al. | The Spatiotemporal Deposition of Lysophosphatidylcholine Within Starch Granules of Maize Endosperm and its Relationships to the Expression of Genes Involved in Endoplasmic Reticulum-Amyloplast Lipid Trafficking and Galactolipid Synthesis. | 2019 | Plant Cell Physiol. | pmid:30295886 |
| Baradaran S et al. | Hesperetin reduces myelin damage and ameliorates glial activation in lysolecithin-induced focal demyelination model of rat optic chiasm. | 2018 | Life Sci. | pmid:30056861 |
| Liu H et al. | Study on a dSPE-LC-MS/MS method for lysophosphatidylcholines and underivatized neurotransmitters in rat brain tissues. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:30125781 |
| Narayanan V et al. | Impairment of frequency-specific responses associated with altered electrical activity patterns in auditory thalamus following focal and general demyelination. | 2018 | Exp. Neurol. | pmid:30048715 |
| Natarajan A et al. | Liquid chromatography-tandem mass spectrometry method for estimation of a panel of lysophosphatidylcholines in dried blood spots for screening of X-linked adrenoleukodystrophy. | 2018 | Clin. Chim. Acta | pmid:30018013 |
| Pleguezuelos-Villa M et al. | A novel ultradeformable liposomes of Naringin for anti-inflammatory therapy. | 2018 | Colloids Surf B Biointerfaces | pmid:29216513 |
| Chen J et al. | Resveratrol alleviates lysophosphatidylcholine-induced damage and inflammation in vascular endothelial cells. | 2018 | Mol Med Rep | pmid:29257345 |
| Drzazga A et al. | 2-OMe-lysophosphatidylcholine analogues are GPR119 ligands and activate insulin secretion from βTC-3 pancreatic cells: Evaluation of structure-dependent biological activity. | 2018 | Biochim. Biophys. Acta | pmid:29079451 |