Lysophosphatidylcholine

Lysophosphatidylcholine is a lipid of Glycerophospholipids (GP) class. Lysophosphatidylcholine is associated with abnormalities such as Ischemia, Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver and Atherosclerosis. The involved functions are known as Inflammation, antagonists, Signal Transduction, Signal Pathways and Saturated. Lysophosphatidylcholine often locates in Body tissue, Head, integral to membrane, Membrane and Extracellular. The associated genes with Lysophosphatidylcholine are RHOA gene, Homologous Gene, GPR4 gene, GPR68 gene and TRPV2 gene. The related lipids are Nonesterified Fatty Acids, lysophosphatidylethanolamine, Lysophosphatidylcholines, Phosphatidylserines and 25-hydroxycholesterol. The related experimental models are Knock-out and Disease model.

Cross Reference

Introduction

To understand associated biological information of Lysophosphatidylcholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lysophosphatidylcholine?

Lysophosphatidylcholine is suspected in Atherosclerosis, Ischemia, Septicemia, Obesity, Exanthema, hypercholesterolemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lysophosphatidylcholine

MeSH term MeSH ID Detail
Arrhythmias, Cardiac D001145 42 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Insulinoma D007340 28 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Pulmonary Edema D011654 23 associated lipids
Peritonitis D010538 38 associated lipids
Proteinuria D011507 30 associated lipids
Arteriosclerosis D001161 86 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Lysophosphatidylcholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lysophosphatidylcholine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Lysophosphatidylcholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lysophosphatidylcholine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Lysophosphatidylcholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lysophosphatidylcholine?

Knock-out

Knock-out are used in the study 'Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice.' (Parks BW et al., 2005) and Knock-out are used in the study 'Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A2.' (Fisher AB et al., 2005).

Disease model

Disease model are used in the study 'Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy.' (Thiele JR et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Lysophosphatidylcholine

Download all related citations
Per page 10 20 50 100 | Total 3448
Authors Title Published Journal PubMed Link
Egelandsdal B et al. The denaturing action of lysophosphatidylcholine as studied by calorimetric and rheological techniques. Chem. Phys. Lipids pmid:2060066
Hawcroft DM and Martin PA Studies on age related changes in the lipids of mouse liver microsomes. Mech. Ageing Dev. pmid:4437211
Hou WY et al. Effect of inhibition of neuropathy target esterase in mouse nervous tissues in vitro on phosphatidylcholine and lysophosphatidylcholine homeostasis. Int. J. Toxicol. pmid:19620706
Killian JA and de Kruijff B The influence of proteins and peptides on the phase properties of lipids. Chem. Phys. Lipids pmid:2427235
Herrmann W et al. [The permeability of isolated phosphatides from normal and atherosclerotic human aortas]. Atherosclerosis pmid:4458690
Garçon DP et al. Removal from the membrane affects the interaction of rat osseous plate ecto-nucleosidetriphosphate diphosphohydrolase-1 with substrates and ions. J. Membr. Biol. pmid:18841405
Ryborg AK et al. Intracutaneous injection of lysophosphatidylcholine induces skin inflammation and accumulation of leukocytes. Acta Derm. Venereol. pmid:11028854
Besterman EM and Gillett MP Inhibition of platelet aggregation by lysolecithin. Atherosclerosis pmid:5135227
Moyon S et al. Efficient Remyelination Requires DNA Methylation. eNeuro pmid:28451635
Kim HY et al. Lysophospholipid profile in serum and liver by high-fat diet and tumor induction in obesity-resistant BALB/c mice. Nutrition pmid:25280424