| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Insulinoma | D007340 | 28 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetic Retinopathy | D003930 | 39 associated lipids |
| Pulmonary Edema | D011654 | 23 associated lipids |
| Peritonitis | D010538 | 38 associated lipids |
| Proteinuria | D011507 | 30 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
Lysophosphatidylcholine
Lysophosphatidylcholine is a lipid of Glycerophospholipids (GP) class. Lysophosphatidylcholine is associated with abnormalities such as Ischemia, Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver and Atherosclerosis. The involved functions are known as Inflammation, antagonists, Signal Transduction, Signal Pathways and Saturated. Lysophosphatidylcholine often locates in Body tissue, Head, integral to membrane, Membrane and Extracellular. The associated genes with Lysophosphatidylcholine are RHOA gene, Homologous Gene, GPR4 gene, GPR68 gene and TRPV2 gene. The related lipids are Nonesterified Fatty Acids, lysophosphatidylethanolamine, Lysophosphatidylcholines, Phosphatidylserines and 25-hydroxycholesterol. The related experimental models are Knock-out and Disease model.
Cross Reference
Introduction
To understand associated biological information of Lysophosphatidylcholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lysophosphatidylcholine?
Lysophosphatidylcholine is suspected in Atherosclerosis, Ischemia, Septicemia, Obesity, Exanthema, hypercholesterolemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lysophosphatidylcholine
PubChem Associated disorders and diseases
What pathways are associated with Lysophosphatidylcholine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lysophosphatidylcholine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Lysophosphatidylcholine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Lysophosphatidylcholine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Lysophosphatidylcholine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Lysophosphatidylcholine?
Knock-out
Knock-out are used in the study 'Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice.' (Parks BW et al., 2005) and Knock-out are used in the study 'Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A2.' (Fisher AB et al., 2005).
Disease model
Disease model are used in the study 'Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy.' (Thiele JR et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Lysophosphatidylcholine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Mengesha AE and Bummer PM | Simple chromatographic method for simultaneous analyses of phosphatidylcholine, lysophosphatidylcholine, and free fatty acids. | 2010 | AAPS PharmSciTech | pmid:20585908 |
| Goda T and Miyahara Y | Calcium-independent binding of human C-reactive protein to lysophosphatidylcholine in supported planar phospholipid monolayers. | 2017 | Acta Biomater | pmid:27815167 |
| Ryborg AK et al. | Intracutaneous injection of lysophosphatidylcholine induces skin inflammation and accumulation of leukocytes. | Acta Derm. Venereol. | pmid:11028854 | |
| Ryborg AK et al. | Lysophosphatidylcholine induces keratinocyte differentiation and upregulation of AP-1- and NF-kappaB DNA-binding activity. | 2004 | Acta Derm. Venereol. | pmid:15844632 |
| Fouchier F et al. | Intralysosomal hydrolysis of thyroglobulin. I. Modulation by lysosomal membrane permeability and exogenous factors. | 1983 | Acta Endocrinol. | pmid:6858548 |
| Larsson-Cohn U et al. | Effects of combined and low-dose gestagen oral contraceptives on plasma lipids; including individual phospholipids. | 1970 | Acta Endocrinol. | pmid:4194179 |
| Garfin SR et al. | Effect of lysolecithin on bovine erythrocyte osmotic fragility. | 1969 | Acta Haematol. | pmid:4982579 |
| Svanborg A and Vikrot O | Plasma lipids during the menstrual cycle. | 1967 | Acta Med Scand | pmid:6066627 |
| Svanborg A and Vikrot O | Plasma cholesterol esterification and lysolecithin production in vitro during pregnancy hyperlipemia. | 1965 | Acta Med Scand | pmid:5850342 |
| Böttiger LE | Serum total phospholipids, lecithin and lysolecithin--normal values in various age groups. | 1973 Jan-Feb | Acta Med Scand | pmid:4705086 |
| Böttiger LE | Erythrocyte sedimentation rate and plasma lipids. | 1973 Jan-Feb | Acta Med Scand | pmid:4705087 |
| Hallberg L et al. | Individual plasma phospholipids in women. A comparison of menstruating and menopausal 48-year-old women. | 1967 | Acta Med Scand | pmid:6017807 |
| Brody S et al. | The effect of some ovulation inhibitors on the lipid metabolism. Preliminary report. | 1966 | Acta Med Scand | pmid:5908686 |
| VIKROT O | QUANTITATIVE DETERMINATION OF PLASMA PHOSPHOLIPIDS IN PREGNANT AND NON-PREGNANT WOMEN, WITH SPECIAL REFERENCE TO LYSOLECITHIN. | 1964 | Acta Med Scand | pmid:14149649 |
| Svanborg A and Vikrot O | Plasma lipids in recurrent jaundice of pregnancy. | 1967 | Acta Med Scand | pmid:6017002 |
| Wallentin L et al. | Studies on plasma lipid and phospholipid composition in pernicious anemia before and after specific treatment. | 1977 | Acta Med Scand | pmid:848351 |
| Vikrot O | Plasma lipids, including individual phospholipids, in pregnant rats. | 1965 | Acta Med Scand | pmid:5892655 |
| Vikrot O et al. | Influence of nicotinic acid on individual plasma phospholipids in hypercholesterolemic subjects. | 1971 Jul-Aug | Acta Med Scand | pmid:5099122 |
| Berlin R et al. | Lysolecithin as a factor influencing erythrocyte sedimentation rate. | 1973 | Acta Med Scand | pmid:4757216 |
| Berlin R et al. | Lipid changes after incubation of normal plasma. | 1969 | Acta Med Scand | pmid:5808642 |
| Berlin R et al. | Increased lecithinase activity after heparin administration. | 1969 | Acta Med Scand | pmid:5808643 |
| Berlin R et al. | Acute myocardial infarction and plasma phospholipid levels. | 1969 | Acta Med Scand | pmid:5808644 |
| Gjone E and Norum KR | Familial serum cholesterol ester deficiency. Clinical study of a patient with a new syndrome. | 1968 Jan-Feb | Acta Med Scand | pmid:5669813 |
| Yegin A et al. | Secretory phospholipase A2 and phospholipids in neural membranes in an experimental epilepsy model. | 2002 | Acta Neurol. Scand. | pmid:12371918 |
| Ammitzboll T et al. | Lysolecithin fusion of cells from multiple sclerosis patients with Vero cells. | 1976 | Acta Neurol. Scand. | pmid:131466 |
| Kunze D et al. | Acylation of lysophosphatidylcholine and glycerolphosphate and fatty acid pattern in phosphatidylcholine and -ethanolamine in microsomes of normal and dystrophic human muscle. | 1986 | Acta Neurol. Scand. | pmid:3705921 |
| Münzel EJ et al. | Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age. | 2014 | Acta Neuropathol Commun | pmid:25022486 |
| Lindback T et al. | Phospholipids in amniotic fluid. I. Relationship of phospholipid concentrations to gestation, maternal disease and fetal outcome. | 1974 | Acta Obstet Gynecol Scand | pmid:4210584 |
| Sandvik O and Hoyem T | Inhibitory effect of lysolecithin on bacterial growth. | 1969 | Acta Pathol Microbiol Scand | pmid:4985022 |
| Mehrishi JN et al. | Changes in the electrophoretic mobility of BP8 ascites tumour cells after treatment with lysolecithin. | 1968 | Acta Pathol Microbiol Scand | pmid:5700275 |
| Nygren B et al. | Phospholipase A-production in Staphylococcus aureus. | 1966 | Acta Pathol Microbiol Scand | pmid:5959847 |
| Soltesz LV and MÃ¥rdh PA | The lytic effect of lysolecithin on acholeplasmas and mycoplasmas. | 1977 | Acta Pathol Microbiol Scand B | pmid:899794 |
| MÃ¥rdh PA and Taylor-Robinson D | The susceptibility of aerobic and anaerobic bacteria, L-phase variants, candida, protozoa and viruses to lysolecithin. | 1974 | Acta Pathol Microbiol Scand B Microbiol Immunol | pmid:4376328 |
| Qin ZX et al. | Effects of lysophosphatidylcholine on beta-amyloid-induced neuronal apoptosis. | 2009 | Acta Pharmacol. Sin. | pmid:19343059 |
| Li Z et al. | Inhibitory effects of cariporide on LPC-induced expression of ICAM-1 and adhesion of monocytes to smooth muscle cells in vitro. | 2006 | Acta Pharmacol. Sin. | pmid:17007739 |
| Deng HF and Xiong Y | Effect of pravastatin on impaired endothelium-dependent relaxation induced by lysophosphatidylcholine in rat aorta. | 2005 | Acta Pharmacol. Sin. | pmid:15659120 |
| Lee EH et al. | Structure-activity relationship of lysophosphatidylcholines in HL-60 human leukemia cells. | 2004 | Acta Pharmacol. Sin. | pmid:15525477 |
| Im DS | Two ligands for a GPCR, proton vs lysolipid. | 2005 | Acta Pharmacol. Sin. | pmid:16297340 |
| Im YJ et al. | Multiple actions of lysophosphatidylcholine in human Jurkat T cells. | 2006 | Acta Pharmacol. Sin. | pmid:16723088 |
| Zhang L et al. | Inhibitory effects of Ginkgo biloba extract on vascular endothelial growth factor in rat aortic endothelial cells. | 2002 | Acta Pharmacol. Sin. | pmid:12370096 |
| Zhang L et al. | Effect of lysophosphatidylcholine on expression of vascular endothelial growth factor in ECV304 cells. | 2001 | Acta Pharmacol. Sin. | pmid:11742586 |
| Olaisson H et al. | Occurrence of phospholipase A2 and lysophospholipase in a gastric H,K-ATPase-containing membrane fraction, and the formation of lysophosphatidylcholine in stimulated pig parietal cells. | 1990 | Acta Physiol. Scand. | pmid:1964531 |
| Albuquerque EX and Thesleff S | Effects of phospholipase A and lysolecithin on some electrical properties of the muscle membrane. | Acta Physiol. Scand. | pmid:5655757 | |
| Eskelinen S and Mela M | Cation permeability and mechanical properties of the erythrocyte membrane under the influence of lysophosphatidylcholine (LPC) in isotonic and hypotonic media. | 1984 | Acta Physiol. Scand. | pmid:6524395 |
| Lagercrantz H | Lipids of the sympathetic nerve trunk vesicles. Comparison with adrenomedullary vesicles. | 1971 | Acta Physiol. Scand. | pmid:5098569 |
| Drzazga A et al. | Lysophosphatidylcholine and lysophosphatidylinosiol--novel promissing signaling molecules and their possible therapeutic activity. | 2014 Nov-Dec | Acta Pol Pharm | pmid:25745761 |
| Lima MS et al. | Triatoma infestans relies on salivary lysophosphatidylcholine to enhance Trypanosoma cruzi transmission. | 2018 | Acta Trop. | pmid:29107570 |
| Dousset V et al. | Lysolecithin-induced demyelination in primates: preliminary in vivo study with MR and magnetization transfer. | 1995 | AJNR Am J Neuroradiol | pmid:7726066 |
| Rosenson RS | Fenofibrate reduces lipoprotein associated phospholipase A2 mass and oxidative lipids in hypertriglyceridemic subjects with the metabolic syndrome. | 2008 | Am. Heart J. | pmid:18294485 |