MeSH term | MeSH ID | Detail |
---|---|---|
Coronary Disease | D003327 | 70 associated lipids |
Coronary Artery Disease | D003324 | 47 associated lipids |
Lysoplasmenylcholine is a lipid of Glycerophospholipids (GP) class. Lysoplasmenylcholine is associated with abnormalities such as Ischemia, Congenital Abnormality and Myocardial Ischemia. The involved functions are known as membrane activity, Action Potentials, Hypoxia, Energy Absorption and Cell Death. Lysoplasmenylcholine often locates in Myocardium, Membrane, Extracellular, Axon and Sarcolemma. The associated genes with Lysoplasmenylcholine are THOC4 gene, POLE gene, SFLL and CA1 gene. The related lipids are Plasmalogens, Phosphatidylserines, Lysophospholipids, plasmenylcholine and lysoplasmenylcholine.
To understand associated biological information of Lysoplasmenylcholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Lysoplasmenylcholine is suspected in Myocardial Ischemia, Ischemia, Congenital Abnormality and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Lysoplasmenylcholine
MeSH term | MeSH ID | Detail |
---|---|---|
Coronary Disease | D003327 | 70 associated lipids |
Coronary Artery Disease | D003324 | 47 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Jurkowitz MS et al. | Identification and characterization of alkenyl hydrolase (lysoplasmalogenase) in microsomes and identification of a plasmalogen-active phospholipase A2 in cytosol of small intestinal epithelium. | 1999 | Biochim. Biophys. Acta | pmid:10064898 |
Albert CJ et al. | Reactive chlorinating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: identification of 2-chlorohexadecanal. | 2001 | J. Biol. Chem. | pmid:11301330 |
Williams SD and Ford DA | Calcium-independent phospholipase A(2) mediates CREB phosphorylation and c-fos expression during ischemia. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11406482 |
Albert CJ et al. | Reactive brominating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: disparate utilization of sodium halides in the production of alpha-halo fatty aldehydes. | 2002 | J. Biol. Chem. | pmid:11836259 |
Liu SJ et al. | Alterations in Ca2+ cycling by lysoplasmenylcholine in adult rabbit ventricular myocytes. | 2003 | Am. J. Physiol., Cell Physiol. | pmid:12456398 |
Martinson BD et al. | Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells. | 2003 | J. Lipid Res. | pmid:12810819 |
HARTREE EF and MANN T | Crystalline lysoplasmalogen (lysophosphatidal choline): preparation from heart muscle and action on erythrocytes and spermatozoa. | 1960 | Biochem. J. | pmid:14400186 |
Davies NJ et al. | Lysoplasmenylethanolamine accumulation in ischemic/reperfused isolated fatty acid-perfused hearts. | 1992 | Circ. Res. | pmid:1576737 |
Meyer MC and McHowat J | Calcium-independent phospholipase A2-catalyzed plasmalogen hydrolysis in hypoxic human coronary artery endothelial cells. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:16943248 |