Lysoplasmenylcholine

Lysoplasmenylcholine is a lipid of Glycerophospholipids (GP) class. Lysoplasmenylcholine is associated with abnormalities such as Ischemia, Congenital Abnormality and Myocardial Ischemia. The involved functions are known as membrane activity, Action Potentials, Hypoxia, Energy Absorption and Cell Death. Lysoplasmenylcholine often locates in Myocardium, Membrane, Extracellular, Axon and Sarcolemma. The associated genes with Lysoplasmenylcholine are THOC4 gene, POLE gene, SFLL and CA1 gene. The related lipids are Plasmalogens, Phosphatidylserines, Lysophospholipids, plasmenylcholine and lysoplasmenylcholine.

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Introduction

To understand associated biological information of Lysoplasmenylcholine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lysoplasmenylcholine?

Lysoplasmenylcholine is suspected in Myocardial Ischemia, Ischemia, Congenital Abnormality and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lysoplasmenylcholine

MeSH term MeSH ID Detail
Coronary Disease D003327 70 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Lysoplasmenylcholine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lysoplasmenylcholine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lysoplasmenylcholine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lysoplasmenylcholine?

Related references are published most in these journals:

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What genes are associated with Lysoplasmenylcholine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lysoplasmenylcholine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lysoplasmenylcholine

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Authors Title Published Journal PubMed Link
Kawasaki T et al. Analysis of platelet phospholipids by high performance liquid chromatography. II--Studies on hitherto unknown peak of phospholipid of human platelets. 1986 Thromb. Res. pmid:3715812
Bourdillon MT et al. Oxidation of Plasmalogen, Low-Density Lipoprotein and RAW 264.7 Cells by Photoactivatable Atomic Oxygen Precursors. 2014 Mar-Apr Photochem. Photobiol. pmid:27096146
Illig HK et al. On the phospholipid metabolism of glial cell primary cultures. III. Utilization of 1-alkenyl-glycerophosphoethanolamine (lysoplasmalogen). 1982 Neurochem. Res. pmid:7155277
Schonefeld M et al. Hypoxia-induced amphiphiles inhibit renal Na+, K(+)-ATPase. 1996 Kidney Int. pmid:8731093
Gunawan J and Debuch H Alkenylhydrolase: a microsomal enzyme activity in rat brain. 1985 J. Neurochem. pmid:3917489
Martinson BD et al. Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells. 2003 J. Lipid Res. pmid:12810819
Hanahan DJ et al. Novel route to preparation of high purity lysoplasmenylethanolamine. 1990 J. Lipid Res. pmid:2086708
Wolf RA and Gross RW Semi-synthetic approach for the preparation of homogeneous plasmenylethanolamine utilizing phospholipase D from Streptomyces chromofuscus. 1985 J. Lipid Res. pmid:4020302
Sedlis SP et al. Lysophosphatidylcholine accumulation in ischemic human myocardium. 1993 J. Lab. Clin. Med. pmid:8426072
Wu LC et al. Purification, identification, and cloning of lysoplasmalogenase, the enzyme that catalyzes hydrolysis of the vinyl ether bond of lysoplasmalogen. 2011 J. Biol. Chem. pmid:21515882
Albert CJ et al. Reactive brominating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: disparate utilization of sodium halides in the production of alpha-halo fatty aldehydes. 2002 J. Biol. Chem. pmid:11836259
Albert CJ et al. Reactive chlorinating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: identification of 2-chlorohexadecanal. 2001 J. Biol. Chem. pmid:11301330
Kramer RM and Deykin D Arachidonoyl transacylase in human platelets. Coenzyme A-independent transfer of arachidonate from phosphatidylcholine to lysoplasmenylethanolamine. 1983 J. Biol. Chem. pmid:6417134
Wolf RA and Gross RW Identification of neutral active phospholipase C which hydrolyzes choline glycerophospholipids and plasmalogen selective phospholipase A2 in canine myocardium. 1985 J. Biol. Chem. pmid:3997869
Illig HK et al. Phospholipid metabolism of glial cell primary cultures, IV. Metabolism of 1-alkenyl-sn-glycero-3-phosphoethanolamine between 1 and 20 hours incubation. 1982 Hoppe-Seyler's Z. Physiol. Chem. pmid:7129362
Gunawan J and Debuch H Liberation of free aldehyde from 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine (lysoplasmalogen) by rat liver microsomes. 1981 Hoppe-Seyler's Z. Physiol. Chem. pmid:7239443
Williams SD and Ford DA Activation of myocardial cAMP-dependent protein kinase by lysoplasmenylcholine. 1997 FEBS Lett. pmid:9450545
Nishimukai M et al. Lymphatic absorption of choline plasmalogen is much higher than that of ethanolamine plasmalogen in rats. 2011 Eur J Nutr pmid:21152926
Davies NJ et al. Lysoplasmenylethanolamine accumulation in ischemic/reperfused isolated fatty acid-perfused hearts. 1992 Circ. Res. pmid:1576737
Caldwell RA and Baumgarten CM Plasmalogen-derived lysolipid induces a depolarizing cation current in rabbit ventricular myocytes. 1998 Circ. Res. pmid:9734476