| MeSH term | MeSH ID | Detail |
|---|---|---|
| Sneddon Syndrome | D018860 | 1 associated lipids |
| Activated Protein C Resistance | D020016 | 1 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Chondrodysplasia Punctata, Rhizomelic | D018902 | 4 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Merino-Montero S et al. | Effects of lactose permease of Escherichia coli on the anisotropy and electrostatic surface potential of liposomes. | 2006 | Biophys. Chem. | pmid:16242835 |
| Jumpsen JA et al. | Fatty acids in blood and intestine following docosahexaenoic acid supplementation in adults with cystic fibrosis. | 2006 | J. Cyst. Fibros. | pmid:16507353 |
| Kaliszewski P et al. | Enhanced levels of Pis1p (phosphatidylinositol synthase) improve the growth of Saccharomyces cerevisiae cells deficient in Rsp5 ubiquitin ligase. | 2006 | Biochem. J. | pmid:16363994 |
| Wichmann O et al. | A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms. | 2006 | Angew. Chem. Int. Ed. Engl. | pmid:16323228 |
| Bourre JM et al. | Fatty acid alterations in liver peroxisomes from n-3-deficient mice. | 2006 | Ann. Nutr. Metab. | pmid:16407648 |
| Lins L et al. | "De novo" design of peptides with specific lipid-binding properties. | 2006 | Biophys. J. | pmid:16275638 |
| Song H et al. | Coordinated alteration of hepatic gene expression in fatty acid and triglyceride synthesis in LCAT-null mice is associated with altered PUFA metabolism. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16105858 |
| Jin JK et al. | Phospholipase D1 is up-regulated in the mitochondrial fraction from the brains of Alzheimer's disease patients. | 2006 | Neurosci. Lett. | pmid:16973278 |
| Hicks AM et al. | Unique molecular signatures of glycerophospholipid species in different rat tissues analyzed by tandem mass spectrometry. | 2006 | Biochim. Biophys. Acta | pmid:16860597 |
| Tseng M et al. | Amycolatopsis taiwanensis sp. nov., from soil. | 2006 | Int. J. Syst. Evol. Microbiol. | pmid:16902013 |
| Tsuda T et al. | Effect of phosphatidylcholine, phosphatidylethanolamine and lysophosphatidylcholine on the protein C/protein S anticoagulation system. | 2006 | Blood Coagul. Fibrinolysis | pmid:16905948 |
| Tsuda T et al. | Effect of phosphatidylcholine, phosphatidylethanolamine and lysophosphatidylcholine on the activated factor X-prothrombin system. | 2006 | Blood Coagul. Fibrinolysis | pmid:16905950 |
| Gardiner C et al. | Detection of acquired resistance to activated protein C associated with antiphospholipid antibodies using a novel clotting assay. | 2006 | Blood Coagul. Fibrinolysis | pmid:16905952 |
| Welsh D et al. | Differential temperature acclimatization responses in the membrane phospholipids of Posthodiplostomum minimum and its second intermediate host, Lepomis macrochirus. | 2006 | J. Parasitol. | pmid:16995394 |
| Besson N et al. | Selective incorporation of docosahexaenoic acid into lysobisphosphatidic acid in cultured THP-1 macrophages. | 2006 | Lipids | pmid:17707985 |
| Bonner PJ and Shimkets LJ | Phospholipid directed motility of surface-motile bacteria. | 2006 | Mol. Microbiol. | pmid:16925549 |
| Matsumoto K et al. | Lipid domains in bacterial membranes. | 2006 | Mol. Microbiol. | pmid:16925550 |
| Bonner PJ et al. | FibA and PilA act cooperatively during fruiting body formation of Myxococcus xanthus. | 2006 | Mol. Microbiol. | pmid:16925559 |
| Sokol DK et al. | Obsessive-compulsive disorder and central nervous system autoimmunity. | 2006 | Br J Psychiatry | pmid:16880498 |
| Tosch W et al. | Molecular species of phosphatidylethanolamine from continuous cultures of Saccharomyces pastorianus syn. carlsbergensis strains. | 2006 | Yeast | pmid:16491465 |
| Arnt L et al. | Membrane activity of biomimetic facially amphiphilic antibiotics. | 2006 | J Phys Chem B | pmid:16494408 |
| Bakken AM et al. | Glycerophospholipid molecular species in platelets and brain tissues - are platelets a good model for neurons? | 2006 | Platelets | pmid:17074725 |
| Mima J et al. | Specific membrane binding of the carboxypeptidase Y inhibitor I(C), a phosphatidylethanolamine-binding protein family member. | 2006 | FEBS J. | pmid:17076703 |
| Li LO et al. | Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes. | 2006 | J. Biol. Chem. | pmid:17028193 |
| Kume H et al. | Serum ethanolamine and hepatocyte proliferation in perinatal and partially hepatectomized rats. | 2006 | Life Sci. | pmid:16872638 |
| Salas JJ et al. | Phospholipid molecular profiles in the seed kernel from different sunflower (Helianthus annuus) mutants. | 2006 | Lipids | pmid:17120935 |
| Moon TC et al. | Ochnaflavone, naturally occurring biflavonoid, inhibits phospholipase A2 dependent phosphatidylethanolamine degradation in a CCl4-induced rat liver microsome. | 2006 | Biol. Pharm. Bull. | pmid:17142963 |
| Yoon SJ et al. | Interaction of N-linked glycans, having multivalent GlcNAc termini, with GM3 ganglioside. | 2006 | Glycoconj. J. | pmid:17115280 |
| Pernet F et al. | Comparison of three solid-phase extraction methods for fatty acid analysis of lipid fractions in tissues of marine bivalves. | 2006 | J Chromatogr A | pmid:17097094 |
| Tanaka A et al. | Peroxisome division is impaired in a CHO cell mutant with an inactivating point-mutation in dynamin-like protein 1 gene. | 2006 | Exp. Cell Res. | pmid:16529741 |
| Dabholkar RD et al. | Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. | 2006 | Int J Pharm | pmid:16616818 |
| Mizushima N | [Methods for monitoring macroautophagy]. | 2006 | Tanpakushitsu Kakusan Koso | pmid:16922435 |
| Mudgil P et al. | Adsorption of lysozyme to phospholipid and meibomian lipid monolayer films. | 2006 | Colloids Surf B Biointerfaces | pmid:16530395 |
| Hirche F et al. | Effect of dietary methionine on plasma and liver cholesterol concentrations in rats and expression of hepatic genes involved in cholesterol metabolism. | 2006 | Br. J. Nutr. | pmid:16611377 |
| Kume H and Sasaki H | Ethanolamine modulates DNA synthesis through epidermal growth factor receptor in rat primary hepatocytes. | 2006 Jan-Feb | In Vitro Cell. Dev. Biol. Anim. | pmid:16618207 |
| Sawant RM et al. | "SMART" drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers. | 2006 Jul-Aug | Bioconjug. Chem. | pmid:16848401 |
| Dubielecka PM et al. | Mitoxantrone changes spectrin-aminophospholipid interactions. | 2006 May-Jun | Mol. Membr. Biol. | pmid:16785207 |
| Mizugishi K et al. | Maternal disturbance in activated sphingolipid metabolism causes pregnancy loss in mice. | 2007 | J. Clin. Invest. | pmid:17885683 |
| Sanmarco M et al. | Antigenic profile, prevalence, and clinical significance of antiphospholipid antibodies in women referred for in vitro fertilization. | 2007 | Ann. N. Y. Acad. Sci. | pmid:17894010 |
| Riekhof WR et al. | Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. | 2007 | J. Biol. Chem. | pmid:17951629 |
| Lelliott CJ et al. | Hepatic PGC-1beta overexpression induces combined hyperlipidemia and modulates the response to PPARalpha activation. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17932310 |
| Hayashi A et al. | Heat deterioration of phospholipids. V. A new rearrangement reaction of sugars and phosphatidylethanolamine. | 2007 | J Oleo Sci | pmid:17898492 |
| Devlin AM et al. | Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabolism in mice with hyperhomocysteinemia. | 2007 | J. Biol. Chem. | pmid:17971455 |
| Nebauer R et al. | The phosphatidylethanolamine level of yeast mitochondria is affected by the mitochondrial components Oxa1p and Yme1p. | 2007 | FEBS J. | pmid:17976194 |
| Saito K et al. | Transbilayer phospholipid flipping regulates Cdc42p signaling during polarized cell growth via Rga GTPase-activating proteins. | 2007 | Dev. Cell | pmid:17981141 |
| Rizzo AM et al. | Antioxidant metabolism in Xenopus laevis embryos is affected by stratospheric balloon flight. | 2007 | Cell Biol. Int. | pmid:17336552 |
| Wen Z and Kim HY | Inhibition of phosphatidylserine biosynthesis in developing rat brain by maternal exposure to ethanol. | 2007 | J. Neurosci. Res. | pmid:17387686 |
| Song Y et al. | Rapid ambient mass spectrometric profiling of intact, untreated bacteria using desorption electrospray ionization. | 2007 | Chem. Commun. (Camb.) | pmid:17279261 |
| Sato T et al. | Poly(ethylene glycol)-conjugated phospholipids in aqueous micellar solutions: hydration, static structure, and interparticle interactions. | 2007 | J Phys Chem B | pmid:17286354 |
| Li D et al. | Seasonal variations of lipid content and composition in Perna viridis. | 2007 | Lipids | pmid:17576610 |
| Sanmarco M et al. | Antiphosphatidylethanolamine antibodies are associated with an increased odds ratio for thrombosis. A multicenter study with the participation of the European Forum on antiphospholipid antibodies. | 2007 | Thromb. Haemost. | pmid:17549297 |
| Tang N et al. | Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin. | 2007 | J. Natl. Cancer Inst. | pmid:17596572 |
| Epand RF et al. | Bacterial lipid composition and the antimicrobial efficacy of cationic steroid compounds (Ceragenins). | 2007 | Biochim. Biophys. Acta | pmid:17599802 |
| Murphy SC et al. | Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum. | 2007 | Blood | pmid:17526861 |
| Li Z et al. | A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis. | 2007 | Biochim. Biophys. Acta | pmid:17513168 |
| Li D et al. | Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells. | 2007 | J. Pharmacol. Sci. | pmid:17895587 |
| Nishida I | [Reverse genetic approaches for the significance of phospholipid metabolism at low temperatures]. | 2007 | Tanpakushitsu Kakusan Koso | pmid:17566349 |
| Park M et al. | Flavobacterium defluvii sp. nov., isolated from activated sludge. | 2007 | Int. J. Syst. Evol. Microbiol. | pmid:17267956 |
| Ji X et al. | [Measurement of components of the phospholipid of the surfactant in irrigating fluid from the nasopharynx of patients with chronic sinusitis]. | 2007 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:17438845 |
| Trcek J et al. | The highly tolerant acetic acid bacterium Gluconacetobacter europaeus adapts to the presence of acetic acid by changes in lipid composition, morphological properties and PQQ-dependent ADH expression. | 2007 | Extremophiles | pmid:17487444 |
| Hidalgo FJ et al. | Effect of tocopherols in the antioxidative activity of oxidized lipid-amine reaction products. | 2007 | J. Agric. Food Chem. | pmid:17488031 |
| Rolla R et al. | Antibodies against oxidized phospholipids in laboratory tests exploring lupus anti-coagulant activity. | 2007 | Clin. Exp. Immunol. | pmid:17488295 |
| Nebauer R et al. | Phosphatidylethanolamine, a limiting factor of autophagy in yeast strains bearing a defect in the carboxypeptidase Y pathway of vacuolar targeting. | 2007 | J. Biol. Chem. | pmid:17428789 |
| Nerlich A et al. | Deficiency in phosphatidylserine decarboxylase activity in the psd1 psd2 psd3 triple mutant of Arabidopsis affects phosphatidylethanolamine accumulation in mitochondria. | 2007 | Plant Physiol. | pmid:17449644 |
| Dolegowska B et al. | Effect of hemodialysis on the content of fatty acids in monolayers of erythrocyte membranes in patients with chronic renal failure. | 2007 | Ren Fail | pmid:17497467 |
| Miyamoto S and Tokuda H | Diverse effects of phospholipids on lipoprotein sorting and ATP hydrolysis by the ABC transporter LolCDE complex. | 2007 | Biochim. Biophys. Acta | pmid:17498646 |
| Wydro P and Hac-Wydro K | Thermodynamic description of the interactions between lipids in ternary Langmuir monolayers: the study of cholesterol distribution in membranes. | 2007 | J Phys Chem B | pmid:17315916 |
| Subramani S and Farré JC | A ubiquitin-like protein involved in membrane fusion. | 2007 | Cell | pmid:17632052 |
| Nakatogawa H et al. | Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion. | 2007 | Cell | pmid:17632063 |
| Róg T et al. | Glycolipid membranes through atomistic simulations: effect of glucose and galactose head groups on lipid bilayer properties. | 2007 | J Phys Chem B | pmid:17676793 |
| Laurinavicius S et al. | Transbilayer distribution of phospholipids in bacteriophage membranes. | 2007 | Biochim. Biophys. Acta | pmid:17658459 |
| Xiao Y et al. | PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid--mechanistic analysis of a familial Cowden disease-associated PTEN mutation. | 2007 | Cell. Signal. | pmid:17324556 |
| Ohe C et al. | Sum frequency generation spectroscopic studies on phase transitions of phospholipid monolayers containing poly(ethylene oxide) lipids at the air-water interface. | 2007 | J Phys Chem B | pmid:17266350 |
| Hwang TL et al. | Cisplatin encapsulated in phosphatidylethanolamine liposomes enhances the in vitro cytotoxicity and in vivo intratumor drug accumulation against melanomas. | 2007 | J. Dermatol. Sci. | pmid:17267180 |
| Buccoliero R et al. | Increased lung surfactant phosphatidylcholine in patients affected by lysosomal storage diseases. | 2007 | J. Inherit. Metab. Dis. | pmid:17994285 |
| Madeja Z et al. | New cationic polyprenyl derivative proposed as a lipofecting agent. | 2007 | Acta Biochim. Pol. | pmid:18066397 |
| Deng L et al. | Isolation and characterization of a mutant defective in utilization of exogenous phosphatidylethanolamine in Saccharomyces cerevisiae. | 2007 | J. Gen. Appl. Microbiol. | pmid:17878665 |
| Horie M et al. | Fluorometric immunoassay based on pH-sensitive dye-encapsulating liposomes and gramicidin channels. | 2007 | Anal. Biochem. | pmid:17718997 |
| Deng L et al. | Construction of a yeast strain with regulatable phospholipid synthesis for analysis of the uptake and metabolism of phosphatidylethanolamine with short acyl chains. | 2007 | Biosci. Biotechnol. Biochem. | pmid:17827694 |
| Li G et al. | New insights into the regulation of cardiolipin biosynthesis in yeast: implications for Barth syndrome. | 2007 | Biochim. Biophys. Acta | pmid:16904369 |
| Takenaka A et al. | Unsaturated phosphatidylethanolamine as effective synergist in combination with alpha-tocopherol. | 2007 | J Oleo Sci | pmid:17898457 |
| Goss R et al. | Lipid dependence of diadinoxanthin solubilization and de-epoxidation in artificial membrane systems resembling the lipid composition of the natural thylakoid membrane. | 2007 | Biochim. Biophys. Acta | pmid:16843433 |
| Dyall SC et al. | Dietary enrichment with omega-3 polyunsaturated fatty acids reverses age-related decreases in the GluR2 and NR2B glutamate receptor subunits in rat forebrain. | 2007 | Neurobiol. Aging | pmid:16500747 |
| Avila RL et al. | Myelin structure and composition in zebrafish. | 2007 | Neurochem. Res. | pmid:16951904 |
| Horibata Y and Hirabayashi Y | Identification and characterization of human ethanolaminephosphotransferase1. | 2007 | J. Lipid Res. | pmid:17132865 |
| Baronas ET et al. | Biomarkers to monitor drug-induced phospholipidosis. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17156806 |
| Lairion F and Disalvo EA | Effect of arbutin on the dipole potential and area per lipid of ester and ether phosphatidylcholine and phosphatidyl ethanolamine monolayers. | 2007 | Biochim. Biophys. Acta | pmid:17257579 |
| Zhu X et al. | Regulation of eosinophil adhesion by lysophosphatidylcholine via a non-store-operated Ca2+ channel. | 2007 | Am. J. Respir. Cell Mol. Biol. | pmid:17218614 |
| Stark B et al. | Association of vasoactive intestinal peptide with polymer-grafted liposomes: structural aspects for pulmonary delivery. | 2007 | Biochim. Biophys. Acta | pmid:17204237 |
| Grossfield A et al. | Convergence of molecular dynamics simulations of membrane proteins. | 2007 | Proteins | pmid:17243153 |
| Aranda FJ et al. | Thermodynamics of the interaction of a dirhamnolipid biosurfactant secreted by Pseudomonas aeruginosa with phospholipid membranes. | 2007 | Langmuir | pmid:17243729 |
| Matsushita M et al. | Structure of Atg5.Atg16, a complex essential for autophagy. | 2007 | J. Biol. Chem. | pmid:17192262 |
| Shao Y et al. | Stimulation of ATG12-ATG5 conjugation by ribonucleic acid. | 2007 Jan-Feb | Autophagy | pmid:16963840 |
| Kuma A et al. | LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization. | 2007 Jul-Aug | Autophagy | pmid:17387262 |
| Mysiakina IS and Funtikova NS | [Sporangiospore lipids of the mycelial fungus Mucor ramannianus incapable of dimorphic growth]. | 2007 Mar-Apr | Mikrobiologiia | pmid:17583213 |
| Mizushima N and Yoshimori T | How to interpret LC3 immunoblotting. | 2007 Nov-Dec | Autophagy | pmid:17611390 |
| Tereshina VM et al. | [Biochemical aspects of basidiospore maturation in Agaricus bisporus at various temperatures]. | 2007 Sep-Oct | Mikrobiologiia | pmid:18069322 |
| Vance JE | Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically related aminophospholipids. | 2008 | J. Lipid Res. | pmid:18204094 |
| Zhao M et al. | 99mTc-labeled duramycin as a novel phosphatidylethanolamine-binding molecular probe. | 2008 | J. Nucl. Med. | pmid:18632826 |
| Rostovtseva TK and Bezrukov SM | VDAC regulation: role of cytosolic proteins and mitochondrial lipids. | 2008 | J. Bioenerg. Biomembr. | pmid:18654841 |