| MeSH term | MeSH ID | Detail |
|---|---|---|
| Activated Protein C Resistance | D020016 | 1 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Sneddon Syndrome | D018860 | 1 associated lipids |
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Chondrodysplasia Punctata, Rhizomelic | D018902 | 4 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| MATCHES JR et al. | PHOSPHOLIPIDS IN VEGETATIVE CELLS AND SPORES OF BACILLUS POLYMYXA. | 1964 | J. Bacteriol. | pmid:14102851 |
| HUSTON CK et al. | LIPIDS OF SARCINA LUTEA. 3. COMPOSITION OF THE COMPLEX LIPIDS. | 1965 | J. Bacteriol. | pmid:14273659 |
| ANSELL GB and SPANNER S | THE MAGNESIUM-ION-DEPENDENT CLEAVAGE OF THE VINYL ETHER LINKAGE OF BRAIN ETHANOLAMINE PLASMALOGEN. | 1965 | Biochem. J. | pmid:14342238 |
| TAYLOR JF and HODGSON E | THE ORIGIN OF PHOSPHOLIPID ETHANOLAMINE IN THE BLOWFLY, PHORMIA REGINA (MEIG.). | 1965 | J. Insect Physiol. | pmid:14330760 |
| MOORE JH and WILLIAMS DL | STUDIES ON THE COMPOSITION AND STRUCTURE OF THE PHOSPHATIDYLCHOLINE, PHOSPHATIDYLETHANOLAMINE AND TRIGLYCERIDE ISOLATED FROM RABBIT LIVER. | 1965 | Biochim. Biophys. Acta | pmid:14290822 |
| REHBINDER D and GREENBERG DM | STUDIES ON THE METHYLATION OF ETHANOLAMINE PHOSPHATIDES BY LIVER PREPARATIONS. | 1965 | Arch. Biochem. Biophys. | pmid:14281933 |
| ROOTS BI and JOHNSTON PV | LIPIDS OF ISOLATED NEURONS. | 1965 | Biochem. J. | pmid:14342249 |
| Marinetti GV | Arrangement of phosphatidylserine and phosphatidylethanolamine in the erythrocyte membrane. | 1977 | Biochim. Biophys. Acta | pmid:16250335 |
| Pietsch A and Lorenz RL | Rapid separation of the major phospholipid classes on a single aminopropyl cartridge. | 1993 | Lipids | pmid:27483556 |
| Xu Z et al. | Synthesis and characterization of oligomaltose-grafted lipids with application to liposomes. | 2002 | J Colloid Interface Sci | pmid:16290762 |
| Sehayek E et al. | Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol. | 2003 | J. Lipid Res. | pmid:12810817 |
| Prades J et al. | Effects of unsaturated fatty acids and triacylglycerols on phosphatidylethanolamine membrane structure. | 2003 | J. Lipid Res. | pmid:12810821 |
| Noga AA and Vance DE | Insights into the requirement of phosphatidylcholine synthesis for liver function in mice. | 2003 | J. Lipid Res. | pmid:12837848 |
| Casals E et al. | Physical stability of liposomes bearing hemostatic activity. | 2003 | Chem. Phys. Lipids | pmid:14499472 |
| Zhang W et al. | Separation and purification of phosphatidylcholine and phosphatidylethanolamine from soybean degummed oil residues by using solvent extraction and column chromatography. | 2003 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:14643513 |
| Dura M et al. | Kinetics of cardiac RyR channel gating studied at high temporal resolution. | 2003 | Physiol Res | pmid:14535832 |
| Adibhatla RM et al. | Phospholipase A2, hydroxyl radicals, and lipid peroxidation in transient cerebral ischemia. | 2003 | Antioxid. Redox Signal. | pmid:14580322 |
| Alvis SJ et al. | Interactions of anionic phospholipids and phosphatidylethanolamine with the potassium channel KcsA. | 2003 | Biophys. J. | pmid:14645072 |
| Kim KH et al. | Membrane properties induced by anionic phospholipids and phosphatidylethanolamine are critical for the membrane binding and catalytic activity of human cytochrome P450 3A4. | 2003 | Biochemistry | pmid:14690448 |
| Avrahami D and Shai Y | Bestowing antifungal and antibacterial activities by lipophilic acid conjugation to D,L-amino acid-containing antimicrobial peptides: a plausible mode of action. | 2003 | Biochemistry | pmid:14674771 |